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Latency and interval therapy affect the evolution in metastatic colorectal cancer

The cohort of 15 patients included ten patients with available tissue from the primary tumor and ≥1 metastatic site, four patients with pairs of metastases only, and one patient with an anastomotic recurrence five years after initial resection of the primary tumor

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Latency and interval therapy affect the evolution in metastatic colorectal cancer

Data availability and access Our data is available from the EGA sequence archives. Aligned sequence data (Bam files) is archived with the EGA. Access is available upon successful application to the DAC. Our EGA Study page reports datasets that can be obtained from the EGA following an application to the DAC. This list is accessible here: . Acknowledgment and citation Manuscripts, Posters and Presentations We ask that all use of data, be acknowledged as follows in the methods section of manuscripts, if possible, or elsewhere in the main text of the manuscript: This research used data available from the European Genome-phenome Archive of the European Bioinformatics Institute (accession numbers: study EGAS00001003646 and dataset(s) EGAD00...). Please also cite the source of the data in any manuscript based on its analysis, as follows: Hamid Nikbakht1,2, Selin Jessa1,2, Mahadeo A. Sukhai3, Madeleine Arseneault1,2, Tong Zhang3, Louis Letourneau2, Mariam Thomas3, Mathieu Bourgey2, Michael. H. A. Roehrl4,5, Robert Eveleigh 2, Eric X. Chen3, Monica Krzyzanowska3, Malcolm J. Moore3, Amanda Giesler3, Celeste Yu3, Philippe L. Bedard3, Suzanne Kamel-Reid3. Jacek Majewski1,2, Lilian L. Siu3, Yasser Riazalhosseini1,2, Donna M. Graham3. Latency and interval therapy affect the evolution in metastatic colorectal cancer. Scientific Reports Accessing the REACT aligned sequence data (controlled access data) To protect the interests of research participants, REACT datasets are only available to researchers after an application for access has been approved by a ‘Data Access Committee’. This data is called ‘controlled access’ data and approved researchers must agree to specific conditions for using it such as keeping it secure and only using it for approved purposes. Controlled access REACT datasets are archived at the EGA (the European Genome-phenome Archive). The REACT Data Access Committee will review requests for access to controlled access REACT data stored at the EGA. To apply for access to this controlled access data, please send an email to and to receive the Application for Access to REACT Controlled Data Form. You will be asked to provide the following details: * The principal applicant’s name, title, position, affiliation, email address, institutional website and mailing address. * The name, title, position, affiliation, email address and mailing address of the applicant’s institutional representative. * The name, title, position, affiliation, and email address of any personnel or students who need access to the data. * Any other information needed for unique authentication of the applicant, personnel and students. * A scientific abstract providing a brief (approx. 500-word) overview of the research to be carried out, including the proposed uses of the data requested. * A list of three publications authored or co-authored by the principal applicant which are relevant to the current project. * A lay summary describing the project to a general audience.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001003646 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002462674 bam 4.5 GB
EGAF00002462675 bam 12.3 GB
EGAF00002462676 bam 12.0 GB
EGAF00002462677 bam 10.2 GB
EGAF00002462678 bam 3.4 GB
EGAF00002462679 bam 9.8 GB
EGAF00002462680 bam 10.4 GB
EGAF00002462681 bam 11.9 GB
EGAF00002462682 bam 7.0 GB
EGAF00002462683 bam 11.7 GB
EGAF00002462684 bam 8.9 GB
EGAF00002462685 bam 8.9 GB
EGAF00002462686 bam 1.5 GB
EGAF00002462687 bam 8.1 GB
EGAF00002462688 bam 17.0 GB
EGAF00002462689 bam 7.7 GB
EGAF00002462690 bam 10.7 GB
EGAF00002462691 bam 13.6 GB
EGAF00002462692 bam 6.4 GB
EGAF00002462693 bam 3.1 GB
EGAF00002462694 bam 14.7 GB
EGAF00002462695 bam 11.6 GB
EGAF00002462696 bam 13.5 GB
EGAF00002462697 bam 14.7 GB
EGAF00002462698 bam 9.6 GB
EGAF00002462699 bam 15.5 GB
EGAF00002462700 bam 11.6 GB
EGAF00002462701 bam 15.4 GB
EGAF00002462702 bam 11.6 GB
EGAF00002462703 bam 2.0 GB
EGAF00002462704 bam 6.1 GB
EGAF00002462705 bam 9.4 GB
EGAF00002462706 bam 14.1 GB
EGAF00002462707 bam 11.1 GB
EGAF00002462708 bam 7.1 GB
EGAF00002462709 bam 11.6 GB
36 Files (358.8 GB)