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Next gen seq of eye cancers (2019-08-14)

Retinoblastoma (RB), the commonest eye cancer in children was the first cancer for which a genetic cause was identified: the Rb1 gene is a tumour suppressor gene that is mutated in RB. The Rb1 gene defect alone does not predict the clinical outcome. We propose to study other possible mechanisms: 1. Stepwise further mutations occur in RB, increasing its carcinogenesis. We will sequence the whole genome in RB tissue, and relate the different genes expressed to the treatments used. 2. Extracellular matric proteins contribute to a tumour permissive environment for RB to continue to grow. This includes Samll Leucine Rich Proteoglycans (SLRP), a family of 15 secreted extracellular matrix proteins involved in eye development. 3. Cancer stem cells (CSC), a subpopulation of treatment resistant cells, drive RB tumours, and whether these stem cells can be manipulated for new therapies. The aim of this study is to assist finding targeted diagnostic techniques and treatments for RB. . This dataset contains all the data available for this study on 2019-08-14.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001002309 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00001991214 cram 2.4 GB
EGAF00001991215 cram 2.5 GB
EGAF00001991216 cram 2.6 GB
EGAF00001991217 cram 2.0 GB
EGAF00001991218 cram 2.4 GB
EGAF00001991219 cram 2.3 GB
EGAF00001991220 cram 2.2 GB
EGAF00001991221 cram 2.7 GB
EGAF00001991222 cram 2.4 GB
EGAF00001991223 cram 2.4 GB
EGAF00001991224 cram 2.3 GB
EGAF00001991225 cram 2.4 GB
EGAF00001991226 cram 2.5 GB
EGAF00001991227 cram 2.6 GB
EGAF00001991228 cram 2.3 GB
EGAF00001991229 cram 2.6 GB
EGAF00001991230 cram 2.3 GB
EGAF00001991231 cram 2.5 GB
EGAF00001991232 cram 2.6 GB
EGAF00001991233 cram 2.0 GB
EGAF00001991234 cram 2.4 GB
EGAF00001991235 cram 2.2 GB
EGAF00001991236 cram 2.2 GB
EGAF00001991237 cram 2.6 GB
EGAF00001991238 cram 2.3 GB
EGAF00001991239 cram 2.3 GB
EGAF00001991240 cram 2.3 GB
EGAF00001991241 cram 2.4 GB
EGAF00001991242 cram 2.5 GB
EGAF00001991243 cram 2.5 GB
EGAF00001991244 cram 2.2 GB
EGAF00001991245 cram 2.5 GB
EGAF00001991246 cram 2.3 GB
EGAF00001991247 cram 2.5 GB
EGAF00001991248 cram 2.6 GB
EGAF00001991249 cram 2.0 GB
EGAF00001991250 cram 2.4 GB
EGAF00001991251 cram 2.2 GB
EGAF00001991252 cram 2.2 GB
EGAF00001991253 cram 2.7 GB
EGAF00001991254 cram 2.4 GB
EGAF00001991255 cram 2.3 GB
EGAF00001991256 cram 2.3 GB
EGAF00001991257 cram 2.4 GB
EGAF00001991258 cram 2.5 GB
EGAF00001991259 cram 2.5 GB
EGAF00001991260 cram 2.2 GB
EGAF00001991261 cram 2.5 GB
EGAF00001991262 cram 2.3 GB
EGAF00001991263 cram 2.5 GB
EGAF00001991264 cram 2.6 GB
EGAF00001991265 cram 2.0 GB
EGAF00001991266 cram 2.4 GB
EGAF00001991267 cram 2.2 GB
EGAF00001991268 cram 2.2 GB
EGAF00001991269 cram 2.7 GB
EGAF00001991270 cram 2.4 GB
EGAF00001991271 cram 2.3 GB
EGAF00001991272 cram 2.3 GB
EGAF00001991273 cram 2.4 GB
EGAF00001991274 cram 2.5 GB
EGAF00001991275 cram 2.5 GB
EGAF00001991276 cram 2.2 GB
EGAF00001991277 cram 2.5 GB
EGAF00001991278 cram 2.3 GB
EGAF00001991279 cram 2.5 GB
EGAF00001991280 cram 2.6 GB
EGAF00001991281 cram 2.0 GB
EGAF00001991282 cram 2.4 GB
EGAF00001991283 cram 2.2 GB
EGAF00001991284 cram 2.2 GB
EGAF00001991285 cram 2.7 GB
EGAF00001991286 cram 2.4 GB
EGAF00001991287 cram 2.3 GB
EGAF00001991288 cram 2.3 GB
EGAF00001991289 cram 2.4 GB
EGAF00001991290 cram 2.5 GB
EGAF00001991291 cram 2.5 GB
EGAF00001991292 cram 2.2 GB
EGAF00001991293 cram 2.5 GB
EGAF00001991294 cram 2.4 GB
EGAF00001991295 cram 2.5 GB
EGAF00001991296 cram 2.6 GB
EGAF00001991297 cram 2.0 GB
EGAF00001991298 cram 2.4 GB
EGAF00001991299 cram 2.3 GB
EGAF00001991300 cram 2.2 GB
EGAF00001991301 cram 2.7 GB
EGAF00001991302 cram 2.4 GB
EGAF00001991303 cram 2.4 GB
EGAF00001991304 cram 2.3 GB
EGAF00001991305 cram 2.4 GB
EGAF00001991306 cram 2.5 GB
EGAF00001991307 cram 2.6 GB
EGAF00001991308 cram 2.2 GB
EGAF00001991309 cram 2.5 GB
EGAF00001991310 cram 2.4 GB
EGAF00001991311 cram 2.6 GB
EGAF00001991312 cram 2.7 GB
EGAF00001991313 cram 2.1 GB
EGAF00001991314 cram 2.5 GB
EGAF00001991315 cram 2.3 GB
EGAF00001991316 cram 2.3 GB
EGAF00001991317 cram 2.8 GB
EGAF00001991318 cram 2.5 GB
EGAF00001991319 cram 2.4 GB
EGAF00001991320 cram 2.4 GB
EGAF00001991321 cram 2.5 GB
EGAF00001991322 cram 2.6 GB
EGAF00001991323 cram 2.7 GB
EGAF00001991324 cram 2.3 GB
EGAF00001991325 cram 2.6 GB
EGAF00001991326 cram 2.4 GB
EGAF00001991327 cram 2.5 GB
EGAF00001991328 cram 2.6 GB
EGAF00001991329 cram 2.0 GB
EGAF00001991330 cram 2.4 GB
EGAF00001991331 cram 2.2 GB
EGAF00001991332 cram 2.2 GB
EGAF00001991333 cram 2.7 GB
EGAF00001991334 cram 2.4 GB
EGAF00001991335 cram 2.3 GB
EGAF00001991336 cram 2.3 GB
EGAF00001991337 cram 2.4 GB
EGAF00001991338 cram 2.5 GB
EGAF00001991339 cram 2.5 GB
EGAF00001991340 cram 2.2 GB
EGAF00001991341 cram 2.5 GB
EGAF00001991342 cram 2.5 GB
EGAF00001991343 cram 2.6 GB
EGAF00001991344 cram 2.8 GB
EGAF00001991345 cram 2.1 GB
EGAF00001991346 cram 2.5 GB
EGAF00001991347 cram 2.4 GB
EGAF00001991348 cram 2.4 GB
EGAF00001991349 cram 2.9 GB
EGAF00001991350 cram 2.5 GB
EGAF00001991351 cram 2.5 GB
EGAF00001991352 cram 2.4 GB
EGAF00001991353 cram 2.6 GB
EGAF00001991354 cram 2.6 GB
EGAF00001991355 cram 2.7 GB
EGAF00001991356 cram 2.4 GB
EGAF00001991357 cram 2.7 GB
EGAF00001991358 cram 2.5 GB
EGAF00001991359 cram 2.7 GB
EGAF00001991360 cram 2.8 GB
EGAF00001991361 cram 2.1 GB
EGAF00001991362 cram 2.5 GB
EGAF00001991363 cram 2.4 GB
EGAF00001991364 cram 2.4 GB
EGAF00001991365 cram 2.9 GB
EGAF00001991366 cram 2.5 GB
EGAF00001991367 cram 2.5 GB
EGAF00001991368 cram 2.4 GB
EGAF00001991369 cram 2.6 GB
EGAF00001991370 cram 2.7 GB
EGAF00001991371 cram 2.7 GB
EGAF00001991372 cram 2.4 GB
EGAF00001991373 cram 2.7 GB
EGAF00001991374 cram 2.5 GB
EGAF00001991375 cram 2.7 GB
EGAF00001991376 cram 2.8 GB
EGAF00001991377 cram 2.1 GB
EGAF00001991378 cram 2.5 GB
EGAF00001991379 cram 2.4 GB
EGAF00001991380 cram 2.4 GB
EGAF00001991381 cram 2.9 GB
EGAF00001991382 cram 2.5 GB
EGAF00001991383 cram 2.5 GB
EGAF00001991384 cram 2.4 GB
EGAF00001991385 cram 2.6 GB
EGAF00001991386 cram 2.6 GB
EGAF00001991387 cram 2.7 GB
EGAF00001991388 cram 2.4 GB
EGAF00001991389 cram 2.7 GB
EGAF00001991390 cram 2.5 GB
EGAF00001991391 cram 2.7 GB
EGAF00001991392 cram 2.8 GB
EGAF00001991393 cram 2.2 GB
EGAF00001991394 cram 2.6 GB
EGAF00001991395 cram 2.5 GB
EGAF00001991396 cram 2.4 GB
EGAF00001991397 cram 2.9 GB
EGAF00001991398 cram 2.6 GB
EGAF00001991399 cram 2.5 GB
EGAF00001991400 cram 2.5 GB
EGAF00001991401 cram 2.6 GB
EGAF00001991402 cram 2.7 GB
EGAF00001991403 cram 2.8 GB
EGAF00001991404 cram 2.4 GB
EGAF00001991405 cram 2.7 GB
EGAF00001991406 cram 2.5 GB
EGAF00001991407 cram 2.7 GB
EGAF00001991408 cram 2.8 GB
EGAF00001991409 cram 2.1 GB
EGAF00001991410 cram 2.5 GB
EGAF00001991411 cram 2.4 GB
EGAF00001991412 cram 2.4 GB
EGAF00001991413 cram 2.9 GB
EGAF00001991414 cram 2.5 GB
EGAF00001991415 cram 2.5 GB
EGAF00001991416 cram 2.4 GB
EGAF00001991417 cram 2.6 GB
EGAF00001991418 cram 2.6 GB
EGAF00001991419 cram 2.7 GB
EGAF00001991420 cram 2.4 GB
EGAF00001991421 cram 2.7 GB
EGAF00001991422 cram 2.5 GB
EGAF00001991423 cram 2.7 GB
EGAF00001991424 cram 2.8 GB
EGAF00001991425 cram 2.1 GB
EGAF00001991426 cram 2.5 GB
EGAF00001991427 cram 2.4 GB
EGAF00001991428 cram 2.4 GB
EGAF00001991429 cram 2.9 GB
EGAF00001991430 cram 2.5 GB
EGAF00001991431 cram 2.5 GB
EGAF00001991432 cram 2.4 GB
EGAF00001991433 cram 2.6 GB
EGAF00001991434 cram 2.6 GB
EGAF00001991435 cram 2.7 GB
EGAF00001991436 cram 2.4 GB
EGAF00001991437 cram 2.7 GB
EGAF00001991438 cram 2.5 GB
EGAF00001991439 cram 2.6 GB
EGAF00001991440 cram 2.8 GB
EGAF00001991441 cram 2.1 GB
EGAF00001991442 cram 2.5 GB
EGAF00001991443 cram 2.4 GB
EGAF00001991444 cram 2.4 GB
EGAF00001991445 cram 2.8 GB
EGAF00001991446 cram 2.5 GB
EGAF00001991447 cram 2.5 GB
EGAF00001991448 cram 2.4 GB
EGAF00001991449 cram 2.6 GB
EGAF00001991450 cram 2.6 GB
EGAF00001991451 cram 2.7 GB
EGAF00001991452 cram 2.4 GB
EGAF00001991453 cram 2.6 GB
EGAF00001991454 cram 2.5 GB
EGAF00001991455 cram 2.6 GB
EGAF00001991456 cram 2.7 GB
EGAF00001991457 cram 2.1 GB
EGAF00001991458 cram 2.5 GB
EGAF00001991459 cram 2.4 GB
EGAF00001991460 cram 2.3 GB
EGAF00001991461 cram 2.8 GB
EGAF00001991462 cram 2.5 GB
EGAF00001991463 cram 2.5 GB
EGAF00001991464 cram 2.4 GB
EGAF00001991465 cram 2.6 GB
EGAF00001991466 cram 2.6 GB
EGAF00001991467 cram 2.7 GB
EGAF00001991468 cram 2.3 GB
EGAF00001991469 cram 2.6 GB
EGAF00002404800 cram 8.5 GB
EGAF00002404801 cram 5.7 GB
EGAF00002404802 cram 5.4 GB
EGAF00002404803 cram 5.8 GB
EGAF00002404804 cram 5.3 GB
EGAF00002404805 cram 5.5 GB
EGAF00002404806 cram 5.6 GB
EGAF00002404807 cram 5.8 GB
EGAF00002404808 cram 5.4 GB
EGAF00002404809 cram 5.8 GB
EGAF00002404810 cram 5.5 GB
EGAF00002404811 cram 5.6 GB
EGAF00002404812 cram 5.7 GB
EGAF00002404813 cram 5.4 GB
EGAF00002404814 cram 5.8 GB
EGAF00002404815 cram 5.3 GB
EGAF00002404816 cram 5.4 GB
EGAF00002404817 cram 5.7 GB
EGAF00002404818 cram 5.8 GB
EGAF00002404819 cram 5.3 GB
EGAF00002404820 cram 5.5 GB
EGAF00002404821 cram 5.7 GB
EGAF00002404822 cram 5.8 GB
EGAF00002404823 cram 5.5 GB
EGAF00002404824 cram 6.0 GB
EGAF00002404825 cram 5.4 GB
EGAF00002404826 cram 5.5 GB
EGAF00002404827 cram 5.5 GB
EGAF00002404828 cram 5.3 GB
EGAF00002404829 cram 5.8 GB
EGAF00002404830 cram 5.4 GB
EGAF00002404831 cram 5.2 GB
EGAF00002404832 cram 5.1 GB
EGAF00002404833 cram 5.0 GB
EGAF00002404834 cram 5.1 GB
EGAF00002404835 cram 5.5 GB
EGAF00002404836 cram 5.4 GB
EGAF00002404837 cram 6.0 GB
EGAF00002404838 cram 5.4 GB
EGAF00002404839 cram 5.4 GB
EGAF00002404840 cram 5.7 GB
EGAF00002404841 cram 6.4 GB
EGAF00002404842 cram 5.1 GB
EGAF00002404843 cram 5.5 GB
EGAF00002404844 cram 5.5 GB
EGAF00002404845 cram 6.2 GB
EGAF00002404846 cram 4.8 GB
EGAF00002404847 cram 5.6 GB
EGAF00002404848 cram 5.3 GB
EGAF00002404849 cram 5.7 GB
EGAF00002404850 cram 5.2 GB
EGAF00002404851 cram 5.5 GB
EGAF00002404852 cram 5.2 GB
EGAF00002404974 cram 9.1 GB
EGAF00002404975 cram 9.0 GB
EGAF00002404976 cram 8.4 GB
EGAF00002404977 cram 8.8 GB
EGAF00002404978 cram 8.9 GB
EGAF00002404979 cram 8.8 GB
EGAF00002404980 cram 8.1 GB
EGAF00002413670 cram 5.3 GB
EGAF00002413671 cram 5.4 GB
EGAF00002413672 cram 5.9 GB
EGAF00002413673 cram 5.3 GB
EGAF00002413674 cram 6.2 GB
EGAF00002413675 cram 5.9 GB
EGAF00002413676 cram 5.1 GB
EGAF00002413677 cram 5.4 GB
EGAF00002413678 cram 5.9 GB
EGAF00002413679 cram 5.2 GB
EGAF00002413680 cram 5.2 GB
EGAF00002413681 cram 5.6 GB
EGAF00002413682 cram 5.1 GB
EGAF00002413765 cram 5.7 GB
EGAF00002413766 cram 5.0 GB
EGAF00002413767 cram 6.2 GB
EGAF00002413768 cram 4.9 GB
EGAF00002413769 cram 5.6 GB
EGAF00002413770 cram 5.8 GB
EGAF00002413771 cram 5.1 GB
EGAF00002413772 cram 6.1 GB
EGAF00002413773 cram 5.5 GB
EGAF00002413774 cram 5.8 GB
EGAF00002413775 cram 6.0 GB
EGAF00002413776 cram 12.0 GB
EGAF00002413777 cram 12.4 GB
EGAF00002413778 cram 12.9 GB
EGAF00002437194 cram 11.5 GB
EGAF00002437253 cram 11.9 GB
EGAF00002437254 cram 12.0 GB
EGAF00002437255 cram 11.8 GB
EGAF00002437256 cram 12.2 GB
EGAF00002437257 cram 12.3 GB
EGAF00002439986 cram 5.7 GB
EGAF00002439987 cram 6.0 GB
EGAF00002439988 cram 6.0 GB
EGAF00002439989 cram 6.6 GB
EGAF00002439990 cram 5.3 GB
EGAF00002439991 cram 6.5 GB
EGAF00002439992 cram 4.7 GB
EGAF00002439993 cram 5.5 GB
EGAF00002439994 cram 5.6 GB
EGAF00002439995 cram 5.1 GB
EGAF00002439996 cram 5.2 GB
EGAF00002439997 cram 5.8 GB
EGAF00002439998 cram 6.2 GB
EGAF00002439999 cram 5.8 GB
EGAF00002440000 cram 4.8 GB
EGAF00002440001 cram 5.1 GB
EGAF00002440002 cram 6.2 GB
EGAF00002440051 cram 9.0 GB
EGAF00002440052 cram 8.2 GB
EGAF00002440053 cram 9.4 GB
EGAF00002442073 cram 5.6 GB
EGAF00002442074 cram 5.0 GB
EGAF00002442075 cram 5.4 GB
EGAF00002442076 cram 6.0 GB
EGAF00002442077 cram 5.8 GB
EGAF00002442078 cram 5.8 GB
EGAF00002442079 cram 5.8 GB
EGAF00002442080 cram 6.3 GB
EGAF00002442081 cram 5.1 GB
EGAF00002442082 cram 4.6 GB
EGAF00002442083 cram 5.5 GB
EGAF00002442084 cram 5.3 GB
EGAF00002442085 cram 5.3 GB
EGAF00002442086 cram 5.5 GB
EGAF00002442087 cram 5.6 GB
EGAF00002442088 cram 5.9 GB
EGAF00002442089 cram 4.9 GB
EGAF00002442090 cram 5.1 GB
EGAF00002442091 cram 6.2 GB
EGAF00002442092 cram 5.2 GB
EGAF00002442093 cram 8.8 GB
EGAF00002442094 cram 8.5 GB
EGAF00002443988 cram 5.8 GB
EGAF00002443989 cram 5.3 GB
EGAF00002443990 cram 5.5 GB
EGAF00002443991 cram 6.1 GB
EGAF00002443992 cram 5.6 GB
EGAF00002443993 cram 4.6 GB
EGAF00002443994 cram 5.4 GB
EGAF00002443995 cram 6.4 GB
EGAF00002443996 cram 4.6 GB
EGAF00002443997 cram 4.8 GB
EGAF00002443998 cram 6.2 GB
EGAF00002443999 cram 8.6 GB
EGAF00002444000 cram 8.8 GB
EGAF00002446763 cram 5.7 GB
EGAF00002446764 cram 6.2 GB
EGAF00002446765 cram 6.3 GB
EGAF00002446766 cram 5.1 GB
EGAF00002446767 cram 5.7 GB
EGAF00002446768 cram 5.2 GB
EGAF00002446769 cram 6.5 GB
EGAF00002446770 cram 4.7 GB
EGAF00002446771 cram 5.6 GB
EGAF00002446772 cram 5.4 GB
EGAF00002446773 cram 5.8 GB
EGAF00002446774 cram 5.0 GB
EGAF00002446775 cram 5.4 GB
EGAF00002446776 cram 5.5 GB
EGAF00002446777 cram 5.5 GB
EGAF00002446778 cram 5.6 GB
EGAF00002446779 cram 5.8 GB
EGAF00002446780 cram 4.9 GB
EGAF00002446781 cram 5.6 GB
EGAF00002446782 cram 5.0 GB
EGAF00002446783 cram 9.1 GB
425 Files (1.7 TB)