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MutWP5: CRUK Mutographs of Cancer: Lung: PD38234 (Targeted) (2020-01-29)

Sequencing of LCM-derived microbiopsies from explanted lung from pulmonary fibrosis patient. Goal to assess the mutational burden, spectrum, and clonal dynamics within the tissue. Deep sampling throughout multiple regions of the lung will determine whether there are differences in smoking-related mutation burden in different portions of the lung. Targeted sequencing will be conducted on samples to identify drivers of interest and clonality of the samples, well-performing samples will be sent for subsequent whole-genome sequencing. Results from this portion of the study will be compared to other individuals with smoking-related diseases (COPD, pulmonary fibrosis, lung cancer), and normal, non-smoking lungs. . This dataset contains all the data available for this study on 2020-01-29.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001003325 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002555034 cram 364.2 MB
EGAF00002555035 cram 551.3 MB
EGAF00002555036 cram 595.2 MB
EGAF00002555037 cram 364.1 MB
EGAF00002555038 cram 545.6 MB
EGAF00002555039 cram 626.2 MB
EGAF00002555080 cram 323.7 MB
EGAF00002555081 cram 447.7 MB
EGAF00002555082 cram 528.1 MB
EGAF00002555083 cram 556.7 MB
EGAF00002555084 cram 393.6 MB
EGAF00002555085 cram 356.8 MB
EGAF00002555086 cram 578.8 MB
EGAF00002555087 cram 578.9 MB
EGAF00002555088 cram 592.9 MB
EGAF00002555089 cram 550.2 MB
EGAF00002555090 cram 419.9 MB
EGAF00002555091 cram 476.4 MB
EGAF00002555092 cram 372.4 MB
EGAF00002555093 cram 555.7 MB
EGAF00002555094 cram 424.7 MB
EGAF00002555095 cram 423.4 MB
EGAF00002555096 cram 384.5 MB
EGAF00002555097 cram 513.2 MB
EGAF00002555098 cram 425.2 MB
EGAF00002555099 cram 422.8 MB
EGAF00002555100 cram 463.3 MB
27 Files (12.8 GB)