Dataset
RNAseq data from the study - Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML
| Dataset ID | Technology | Samples |
|---|---|---|
| EGAD00001005949 | Illumina HiSeq 2500 | 39 |
Dataset Description
This study assessed molecular determinants of response in a cohort of patients with AML that were treated with venetoclax in combination with either DNA methyltransferase inhibitors or low dose cytarabine. RNA sequencing was performed on 31 patients from three different response classes [10 Group A - Durable remission (n=10), Group B - Relapsed (n=10) and Group C - Refractory (n=11)]. Library preparation and sequencing was performed at the Australian Genome Research Facility, using the Truseq Stranded mRNA library kit. Technical and batch replicate samples are included. Gene count data are provided with the original publication. The use of the sequencing data is subject to a data transfer agreement and is restricted to ethically approved research into blood cell malignancies and cannot be used to assess germline variants.
Data Use Conditions
DS RS RUO IRB TS
See further information on Data Use Conditions
| Label | Code | Version | Modifier |
|---|---|---|---|
| disease specific research | DUO:0000007 | 2019-01-07 | HP:0004377 |
| research specific restrictions | DUO:0000012 | 2019-01-07 | |
| obsolete research use only | DUO:0000014 | 2019-01-07 | |
| ethics approval required | DUO:0000021 | 2019-01-07 | |
| time limit on use | DUO:0000025 | 2019-01-07 |
