bulkRNA

Bulk RNA-seq for cALL patient-derived PDX samples

74 samples
DAC: EGAC00001001579
Technology: NextSeq 500

Access Policy1 Study Files

Metadata

Request Access

HMB DUO:0000006 (version: 2019-01-07)health or medical or biomedical researchThis data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry.
PUB DUO:0000019 (version: 2019-01-07)publication requiredThis data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community.
US DUO:0000026 (version: 2019-01-07)user specific restrictionThis data use modifier indicates that use is limited to use by approved users.
PS DUO:0000027 (version: 2019-01-07)project specific restrictionThis data use modifier indicates that use is limited to use within an approved project.
IS DUO:0000028 (version: 2019-01-07)institution specific restrictionThis data use modifier indicates that use is limited to use within an approved institution.

The data within this dataset will be made available to researchers from recognised academic institutions that wish to perform further research on related topics.

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom Prof. Tariq Enver grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: Prof. Tariq Enver and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify Prof. Tariq Enver within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify Prof. Tariq Enver prior to any significant changes to the protocol for the Project. 14. The User Institution will notify Prof. Tariq Enver as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. Prof. Tariq Enver may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than Prof. Tariq Enver. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of England and Wales and shall be subject to the exclusive jurisdiction of the English courts.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID	Study Title	Study Type
EGAS00001004407	Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia	Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID	File Type	Size
EGAF00003681858	fastq.gz	1.9 GB
EGAF00003681859	fastq.gz	1.9 GB
EGAF00003681860	fastq.gz	1.1 GB
EGAF00003681861	fastq.gz	1.1 GB
EGAF00003681862	fastq.gz	967.8 MB
EGAF00003681863	fastq.gz	986.1 MB
EGAF00003681864	fastq.gz	1.8 GB
EGAF00003681865	fastq.gz	1.8 GB
EGAF00003681866	fastq.gz	1.4 GB
EGAF00003681867	fastq.gz	1.4 GB
EGAF00003681868	fastq.gz	1.3 GB
EGAF00003681869	fastq.gz	1.3 GB
EGAF00003681870	fastq.gz	1.7 GB
EGAF00003681871	fastq.gz	1.7 GB
EGAF00003681872	fastq.gz	1.6 GB
EGAF00003681873	fastq.gz	1.6 GB
EGAF00003681874	fastq.gz	1.8 GB
EGAF00003681875	fastq.gz	1.9 GB
EGAF00003681876	fastq.gz	713.2 MB
EGAF00003681877	fastq.gz	728.7 MB
EGAF00003681878	fastq.gz	1.9 GB
EGAF00003681879	fastq.gz	1.9 GB
EGAF00003681880	fastq.gz	1.3 GB
EGAF00003681881	fastq.gz	1.3 GB
EGAF00003681882	fastq.gz	973.6 MB
EGAF00003681883	fastq.gz	989.9 MB
EGAF00003681884	fastq.gz	1.4 GB
EGAF00003681885	fastq.gz	1.5 GB
EGAF00003681886	fastq.gz	980.6 MB
EGAF00003681887	fastq.gz	996.5 MB
EGAF00003681888	fastq.gz	1.6 GB
EGAF00003681889	fastq.gz	1.6 GB
EGAF00003681890	fastq.gz	1.3 GB
EGAF00003681891	fastq.gz	1.3 GB
EGAF00003681892	fastq.gz	1.7 GB
EGAF00003681893	fastq.gz	1.8 GB
EGAF00003681894	fastq.gz	1.1 GB
EGAF00003681895	fastq.gz	1.2 GB
EGAF00003681896	fastq.gz	941.3 MB
EGAF00003681897	fastq.gz	962.4 MB
EGAF00003681898	fastq.gz	1.8 GB
EGAF00003681899	fastq.gz	1.8 GB
EGAF00003681900	fastq.gz	1.8 GB
EGAF00003681901	fastq.gz	1.9 GB
EGAF00003681902	fastq.gz	1.5 GB
EGAF00003681903	fastq.gz	1.6 GB
EGAF00003681904	fastq.gz	698.2 MB
EGAF00003681905	fastq.gz	711.6 MB
EGAF00003681906	fastq.gz	1.2 GB
EGAF00003681907	fastq.gz	1.2 GB
EGAF00003681908	fastq.gz	1.5 GB
EGAF00003681909	fastq.gz	1.6 GB
EGAF00003681910	fastq.gz	1.6 GB
EGAF00003681911	fastq.gz	1.7 GB
EGAF00003681912	fastq.gz	1.8 GB
EGAF00003681913	fastq.gz	1.8 GB
EGAF00003681914	fastq.gz	1.6 GB
EGAF00003681915	fastq.gz	1.7 GB
EGAF00003681916	fastq.gz	1.3 GB
EGAF00003681917	fastq.gz	1.4 GB
EGAF00003681918	fastq.gz	1.3 GB
EGAF00003681919	fastq.gz	1.3 GB
EGAF00003681920	fastq.gz	1.2 GB
EGAF00003681921	fastq.gz	1.3 GB
EGAF00003681922	fastq.gz	836.6 MB
EGAF00003681923	fastq.gz	857.9 MB
EGAF00003681924	fastq.gz	1.2 GB
EGAF00003681925	fastq.gz	1.2 GB
EGAF00003681926	fastq.gz	1.4 GB
EGAF00003681927	fastq.gz	1.4 GB
EGAF00003681928	fastq.gz	883.5 MB
EGAF00003681929	fastq.gz	900.7 MB
EGAF00003681930	fastq.gz	869.4 MB
EGAF00003681931	fastq.gz	889.6 MB
EGAF00003681932	fastq.gz	1.9 GB
EGAF00003681933	fastq.gz	2.0 GB
EGAF00003681934	fastq.gz	1.7 GB
EGAF00003681935	fastq.gz	1.9 GB
EGAF00003681936	fastq.gz	1.0 GB
EGAF00003681937	fastq.gz	1.0 GB
EGAF00003681938	fastq.gz	2.1 GB
EGAF00003681939	fastq.gz	2.2 GB
EGAF00003681940	fastq.gz	1.2 GB
EGAF00003681941	fastq.gz	1.3 GB
EGAF00003681942	fastq.gz	1.3 GB
EGAF00003681943	fastq.gz	1.4 GB
EGAF00003681944	fastq.gz	1.4 GB
EGAF00003681945	fastq.gz	1.4 GB
EGAF00003681946	fastq.gz	1.2 GB
EGAF00003681947	fastq.gz	1.3 GB
EGAF00003681948	fastq.gz	1.2 GB
EGAF00003681949	fastq.gz	1.3 GB
EGAF00003681950	fastq.gz	1.4 GB
EGAF00003681951	fastq.gz	1.5 GB
EGAF00003681952	fastq.gz	1.7 GB
EGAF00003681953	fastq.gz	1.7 GB
EGAF00003681954	fastq.gz	1.6 GB
EGAF00003681955	fastq.gz	1.6 GB
EGAF00003681956	fastq.gz	1.4 GB
EGAF00003681957	fastq.gz	1.5 GB
EGAF00003681958	fastq.gz	1.3 GB
EGAF00003681959	fastq.gz	1.3 GB
EGAF00003681960	fastq.gz	1.4 GB
EGAF00003681961	fastq.gz	1.4 GB
EGAF00003681962	fastq.gz	1.9 GB
EGAF00003681963	fastq.gz	2.0 GB
EGAF00003681964	fastq.gz	537.5 MB
EGAF00003681965	fastq.gz	547.1 MB
EGAF00003681966	fastq.gz	1.2 GB
EGAF00003681967	fastq.gz	1.3 GB
EGAF00003681968	fastq.gz	1.4 GB
EGAF00003681969	fastq.gz	1.4 GB
EGAF00003681970	fastq.gz	1.0 GB
EGAF00003681971	fastq.gz	1.1 GB
EGAF00003681972	fastq.gz	1.6 GB
EGAF00003681973	fastq.gz	1.6 GB
EGAF00003681974	fastq.gz	1.8 GB
EGAF00003681975	fastq.gz	1.8 GB
EGAF00003681976	fastq.gz	1.2 GB
EGAF00003681977	fastq.gz	1.2 GB
EGAF00003681978	fastq.gz	1.5 GB
EGAF00003681979	fastq.gz	1.6 GB
EGAF00003681980	fastq.gz	1.5 GB
EGAF00003681981	fastq.gz	1.5 GB
EGAF00003681982	fastq.gz	1.4 GB
EGAF00003681983	fastq.gz	1.5 GB
EGAF00003681984	fastq.gz	1.7 GB
EGAF00003681985	fastq.gz	1.7 GB
EGAF00003681986	fastq.gz	768.3 MB
EGAF00003681987	fastq.gz	782.0 MB
EGAF00003681988	fastq.gz	1.1 GB
EGAF00003681989	fastq.gz	1.1 GB
EGAF00003681990	fastq.gz	1.0 GB
EGAF00003681991	fastq.gz	1.1 GB
EGAF00003681992	fastq.gz	1.1 GB
EGAF00003681993	fastq.gz	1.2 GB
EGAF00003681994	fastq.gz	1.5 GB
EGAF00003681995	fastq.gz	1.6 GB
EGAF00003681996	fastq.gz	788.1 MB
EGAF00003681997	fastq.gz	803.9 MB
EGAF00003681998	fastq.gz	1.2 GB
EGAF00003681999	fastq.gz	1.3 GB
EGAF00003682000	fastq.gz	1.4 GB
EGAF00003682001	fastq.gz	1.5 GB
EGAF00003682002	fastq.gz	938.2 MB
EGAF00003682003	fastq.gz	955.9 MB
EGAF00003682076	fastq.gz	1.0 GB
EGAF00003682077	fastq.gz	1.0 GB
148 Files (202.4 GB)