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Melanoma transcriptome profiling

This dataset includes transcriptome profiling of 68 early-passage metastatic melanoma cell lines. The data are provided as paired-end RNA seq fastq files.

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This dataset, "Multiomic profiling of early-passage melanoma cell lines" comprises sequencing-based data (transcriptome, miRnome, WES) from early-passage cell lines derived from distinct melanoma metastases. Use of the data is permissible upon valid request to the DAC for non-profit research purposes.

DATA ACCESS AGREEMENT This Data Access Agreement (“Agreement”), effective as of the ____ day of _________________, 20__ (“Effective Date”), is by and between The University of Texas M. D. Anderson Cancer Center, an institution of The University of Texas System and an agency of the State of Texas, with an address at 1515 Holcombe Boulevard, Houston, Texas 77030 (“Provider”), and _____________ (“Recipient”) on behalf of its investigator _____________ (“Recipient Investigator”) (collectively, the “Parties”; each, a “Party”). RECITALS Provider maintains the following de-identified data in the European Genome-phenome Archive (EGA) managed by the European Bioinformatics Institute (“Data”); Accession EGAS00001004536: Multiomic profiling of early-passage melanoma cell lines. This dataset contains sequencing data from early-passage cell lines derived from 68 distinct melanoma metastases. The dataset comprises files for paired-end RNA sequencing transcriptome profiling (n=68 samples; fastq), single-end small RNA sequencing microRNA profiling (n=61 samples; fastq), and whole exome sequencing (n=65 samples with paired normal peripheral blood mononuclear cells; bam) and associated metadata. Extended metadata and complete information regarding sample-normal pairings for multi-mapping associations are provided in the supplementary data of the accompanying manuscript. and Provider is willing to allow Recipient to access such Data from the EGA for the internal non-commercial research purposes of (“Purpose”); Use of the data is reserved for Non-Profit Institutions only and all findings must be made available to the public and available to the larger scientific community. Allowable Research Projects must be for cancer-related research. pursuant to the terms of this Agreement. In consideration of the mutual promises and covenants herein, and for other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the Parties agree as follows: 1. The Data will be used solely for the Research by Recipient Investigator and personnel under their immediate supervision at Recipient and may not be transferred to any other investigator or to any third party without prior written permission from Provider. The Material may not be used for any purpose other than the Research, including without limitation for any commercial purpose or for research in human subjects (including, without limitation, in diagnostic testing). 2. Neither Recipient nor Recipient Investigator shall disclose Data to any person or party other than the Recipient Investigator hereunder without Provider’s prior written consent. 3. The Data will be used in compliance with all applicable laws, regulations, and guidelines applicable to the Data, including without limitation any applicable export controls. 4. In any publication resulting from use of the Data, Recipient and Recipient Investigator shall acknowledge Associate Professor Scott E. Woodman (“Provider Investigator”) and Provider as the provider of the Data. 5. This Agreement shall be effective as of the Effective Date and shall remain effective until completion of the Research. Either Party may terminate this Agreement with or without cause upon thirty (30) days’ written notice to the other Party. Upon expiration or termination of this Agreement for any reason, Recipient shall destroy all Data received pursuant to this Agreement. 6. Any notice permitted or required as provided for herein shall be in writing and to the contact and address as noted below or as may be provided by either party to the other in writing from time to time.   Notice to Provider shall be to: Chief Legal Officer The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Blvd., Unit 1674 Houston, Texas 77030 Phone: 713-745-6633; Facsimile: 713-745-6029 With a copy to: The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Blvd., Unit 1676 Office of Research Administration Attn: AVP, Research Administration Houston, TX 77030 Phone: 713-792-3672; Facsimile: 713-792-7455 Notice to Recipient shall be to: __________________________ __________________________ __________________________ __________________________ __________________________ 7. In the event Protected Health Information (“PHI”), as defined by the federal Health Insurance Portability and Accountability Act of 1996 (“HIPAA”), as amended, is inadvertently created, accessed by, and/or disclosed to Recipient in connection with this Agreement, Recipient will immediately notify the Provider and will return to Provider or destroy such PHI, in accordance with the Provider’s instructions. Pending return or destruction of any PHI, Recipient shall maintain the confidentiality of all Data (including the PHI) and use appropriate safeguards to prevent access to, use, or disclosure of Data (including the PHI). 8. PROVIDER MAKES NO REPRESENTATION OR WARRANTY CONCERNING THE MATERIAL, INCLUDING WITHOUT LIMITATION, WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OR ANY OTHER WARRANTY, EXPRESS OR IMPLIED. 9. Recipient Investigator and Recipient accept all liability for any use of the Data and for any loss, claim, or damage which may arise from or in connection with this Agreement or the use, handling or storage of the Data and in no event shall Provider or Provider Investigator be liable for any such use, loss, claim or damage. 10. This Agreement is via the EGA mechanism.   [Insert Recipient Name Here] THE UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER By: By: Name: Name: Title: Title: Date: Date: Read and Understood: Read and Understood: Recipient Scientist: Provider Scientist: Name: Name: Title: Title: Date: Date:

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004536 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00004170762 fastq.gz 2.2 GB
EGAF00004170763 fastq.gz 2.4 GB
EGAF00004170764 fastq.gz 2.4 GB
EGAF00004170765 fastq.gz 2.6 GB
EGAF00004170766 fastq.gz 1.6 GB
EGAF00004170767 fastq.gz 1.7 GB
EGAF00004170768 fastq.gz 2.1 GB
EGAF00004170769 fastq.gz 2.2 GB
EGAF00004170770 fastq.gz 2.3 GB
EGAF00004170771 fastq.gz 2.5 GB
EGAF00004170772 fastq.gz 2.2 GB
EGAF00004170773 fastq.gz 2.3 GB
EGAF00004170774 fastq.gz 2.6 GB
EGAF00004170775 fastq.gz 2.8 GB
EGAF00004170776 fastq.gz 2.1 GB
EGAF00004170777 fastq.gz 2.3 GB
EGAF00004170778 fastq.gz 2.2 GB
EGAF00004170779 fastq.gz 2.4 GB
EGAF00004170780 fastq.gz 2.6 GB
EGAF00004170781 fastq.gz 2.8 GB
EGAF00004170782 fastq.gz 2.8 GB
EGAF00004170783 fastq.gz 3.1 GB
EGAF00004170784 fastq.gz 2.7 GB
EGAF00004170785 fastq.gz 2.9 GB
EGAF00004170786 fastq.gz 2.0 GB
EGAF00004170787 fastq.gz 2.1 GB
EGAF00004170788 fastq.gz 2.6 GB
EGAF00004170789 fastq.gz 2.8 GB
EGAF00004170790 fastq.gz 2.0 GB
EGAF00004170791 fastq.gz 2.2 GB
EGAF00004170792 fastq.gz 2.0 GB
EGAF00004170793 fastq.gz 2.1 GB
EGAF00004170794 fastq.gz 2.1 GB
EGAF00004170795 fastq.gz 2.3 GB
EGAF00004170796 fastq.gz 2.3 GB
EGAF00004170797 fastq.gz 2.5 GB
EGAF00004170798 fastq.gz 1.8 GB
EGAF00004170799 fastq.gz 2.0 GB
EGAF00004170800 fastq.gz 2.0 GB
EGAF00004170801 fastq.gz 2.2 GB
EGAF00004170802 fastq.gz 2.0 GB
EGAF00004170803 fastq.gz 2.2 GB
EGAF00004170804 fastq.gz 3.0 GB
EGAF00004170805 fastq.gz 3.2 GB
EGAF00004170806 fastq.gz 2.3 GB
EGAF00004170807 fastq.gz 2.6 GB
EGAF00004170808 fastq.gz 2.2 GB
EGAF00004170809 fastq.gz 2.3 GB
EGAF00004170810 fastq.gz 1.9 GB
EGAF00004170811 fastq.gz 2.1 GB
EGAF00004170812 fastq.gz 2.5 GB
EGAF00004170813 fastq.gz 2.7 GB
EGAF00004170814 fastq.gz 2.0 GB
EGAF00004170815 fastq.gz 2.1 GB
EGAF00004170816 fastq.gz 1.9 GB
EGAF00004170817 fastq.gz 2.0 GB
EGAF00004170818 fastq.gz 2.5 GB
EGAF00004170819 fastq.gz 2.7 GB
EGAF00004170820 fastq.gz 2.1 GB
EGAF00004170821 fastq.gz 2.2 GB
EGAF00004170822 fastq.gz 2.8 GB
EGAF00004170823 fastq.gz 3.1 GB
EGAF00004170824 fastq.gz 2.2 GB
EGAF00004170825 fastq.gz 2.3 GB
EGAF00004170826 fastq.gz 2.6 GB
EGAF00004170827 fastq.gz 2.8 GB
EGAF00004170828 fastq.gz 2.3 GB
EGAF00004170829 fastq.gz 2.5 GB
EGAF00004170830 fastq.gz 2.2 GB
EGAF00004170831 fastq.gz 2.4 GB
EGAF00004170832 fastq.gz 2.5 GB
EGAF00004170833 fastq.gz 2.7 GB
EGAF00004170834 fastq.gz 2.7 GB
EGAF00004170835 fastq.gz 2.9 GB
EGAF00004170836 fastq.gz 2.8 GB
EGAF00004170837 fastq.gz 3.0 GB
EGAF00004170838 fastq.gz 2.0 GB
EGAF00004170839 fastq.gz 2.1 GB
EGAF00004170840 fastq.gz 2.2 GB
EGAF00004170841 fastq.gz 2.5 GB
EGAF00004170842 fastq.gz 2.0 GB
EGAF00004170843 fastq.gz 2.3 GB
EGAF00004170844 fastq.gz 2.0 GB
EGAF00004170845 fastq.gz 2.2 GB
EGAF00004170846 fastq.gz 2.1 GB
EGAF00004170847 fastq.gz 2.3 GB
EGAF00004170848 fastq.gz 2.2 GB
EGAF00004170849 fastq.gz 2.4 GB
EGAF00004170850 fastq.gz 1.8 GB
EGAF00004170851 fastq.gz 2.1 GB
EGAF00004170852 fastq.gz 2.4 GB
EGAF00004170853 fastq.gz 2.8 GB
EGAF00004170854 fastq.gz 2.2 GB
EGAF00004170855 fastq.gz 2.4 GB
EGAF00004170856 fastq.gz 2.4 GB
EGAF00004170857 fastq.gz 2.6 GB
EGAF00004170858 fastq.gz 1.9 GB
EGAF00004170859 fastq.gz 2.1 GB
EGAF00004170860 fastq.gz 2.1 GB
EGAF00004170861 fastq.gz 2.3 GB
EGAF00004170862 fastq.gz 2.2 GB
EGAF00004170863 fastq.gz 2.4 GB
EGAF00004170864 fastq.gz 2.5 GB
EGAF00004170865 fastq.gz 2.7 GB
EGAF00004170866 fastq.gz 2.3 GB
EGAF00004170867 fastq.gz 2.6 GB
EGAF00004170868 fastq.gz 2.2 GB
EGAF00004170869 fastq.gz 2.4 GB
EGAF00004170870 fastq.gz 1.9 GB
EGAF00004170871 fastq.gz 2.1 GB
EGAF00004170872 fastq.gz 1.9 GB
EGAF00004170873 fastq.gz 2.2 GB
EGAF00004170874 fastq.gz 1.9 GB
EGAF00004170875 fastq.gz 2.1 GB
EGAF00004170876 fastq.gz 2.5 GB
EGAF00004170877 fastq.gz 2.8 GB
EGAF00004170878 fastq.gz 2.3 GB
EGAF00004170879 fastq.gz 2.6 GB
EGAF00004170880 fastq.gz 2.2 GB
EGAF00004170881 fastq.gz 2.4 GB
EGAF00004170882 fastq.gz 2.0 GB
EGAF00004170883 fastq.gz 2.2 GB
EGAF00004170884 fastq.gz 2.4 GB
EGAF00004170885 fastq.gz 2.7 GB
EGAF00004170886 fastq.gz 1.9 GB
EGAF00004170887 fastq.gz 2.1 GB
EGAF00004170888 fastq.gz 2.2 GB
EGAF00004170889 fastq.gz 2.3 GB
EGAF00004170890 fastq.gz 2.7 GB
EGAF00004170891 fastq.gz 3.0 GB
EGAF00004170892 fastq.gz 2.1 GB
EGAF00004170893 fastq.gz 2.2 GB
EGAF00004170894 fastq.gz 3.8 GB
EGAF00004170895 fastq.gz 4.3 GB
EGAF00004170896 fastq.gz 2.0 GB
EGAF00004170897 fastq.gz 2.2 GB
136 Files (320.7 GB)