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COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

To investigate the immune response and mechanisms associated with severe COVID-19, we performed single-cell RNA-seq on nasopharyngeal and bronchial samples from 19 clinically well-characterized patients with moderate or critical disease and from 5 healthy controls. We identified airway epithelial cell types and states vulnerable to SARS-CoV-2 infection. In COVID-19 patients, epithelial cells showed an average threefold increase in expression of the SARS-CoV-2 entry receptor ACE2, which correlated with interferon signals by immune cells. Compared with moderate cases, critical cases exhibited stronger interactions between epithelial and immune cells, as indicated by ligand–receptor expression profiles, and activated immune cells , including inflammatory macrophages expressing CCL2, CCL3, CCL20, CXCL1, CXCL3, CXCL10, IL8, IL1B and TNF . The transcriptional differences in critical cases compared with moderate cases likely contribute to clinical observations of heightened inflammatory tissue damage, lung injury and respiratory failure. Our data suggest that pharmacologic inhibition of the CCR1 and/or CCR5 pathways may suppress immune hyperactivation in critical COVID-19.

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Data Transfer Agreement of Human Genomic Data for Research Purposes (Charité)

Data Transfer Agreement between Charité - Universitätsmedizin Berlin Charitéplatz 1, 10117 Berlin Germany –hereinafter: „CHARITÉ“ – [INSERT INSTITUTION DETAILS full legal name and address] –hereinafter: „RECIPIENT“ – – individually referred to as “PARTY” and/or together referred to as “PARTIES” – Preamble This Data Transfer Agreement governs the terms on which access will be granted to the genotype data generated by CHARITÉ. 1.Definitions “Data” means all and any human genetic data obtained by the RECIPIENT from CHARITÉ. “Data Subject” means a person, to whom Data refers and who has been informed of the purposefor which the Data is held and has given her/his consent thereto. “Intellectual Property” means (i) patents, designs, trade marks and trade names (whetherregistered or unregistered), copyright and related rights, database rights, know-how andconfidential information; (ii) all other intellectual property rights and similar or equivalent rightsanywhere in the world which currently exist or are recognised in the future; and (iii) applications,extensions and renewals in relation to any such rights. “Publications” mean, without limitation, articles published in print journals, electronic journals,reviews, books, posters and other written and verbal presentation of research. “Registered User” means a researcher (or an individual conducting research under the supervision of a researcher) that is employed by the RECIPIENT and is bound by confidentiality and non-use obligations in respect of Data and who has signed this Agreement and has received acknowledgement of its acceptance. For the avoidance of doubt, “Registered User” may also include students, visiting academics, contractors, sub-contractors or independent consultants provided that any such individual is bound by confidentiality and non-use obligations no less onerous then those binding the RECIPIENT’s employees. 2.Obligations of the RECIPIENT 2.1 Confidentiality The RECIPIENT agrees to preserve, at all times, the confidentiality of Data pertaining to identifiable Data Subjects. In particular, the RECIPIENT undertakes not to use, or attempt to use the Data to deliberately compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 2.2 Data Protection 2.2.1 The RECIPIENT agrees to use the Data solely for the approved purpose and project described in the RECIPIENT’s application (Annex 1); use of the Data for a new purpose or project will require a new application and approval. 2.2.2 Data shall not be used for commercial purposes (e.g. diagnostic services). 2.2.3 The RECIPIENT, and her/his Registered Users, shall comply with the obligations contained in the applicable German and EU data protection laws and regulations as amended from time to time. 2.2.4 The RECIPIENT agrees that before he gives any Registered User access to Data, he shall first show the Registered User a copy of this Agreement and shall inform the Registered User that he or she must comply with the obligations contained in this Agreement and sign up to the provisions of this Agreement in the form set out at the end of this Agreement (Annex 2). The RECIPIENT shall provide CHARITÉ with a copy of the Registered User’s acceptance form within ten days of the date of acceptance by the Registered User. 2.2.5 The RECIPIENT agrees not to transfer or disclose the Data, in whole or in part, or any identifiable material derived from the Data, to others, except Registered Users. Should the RECIPIENT wish to share the Data with a collaborator out of the same institution, the third party must make a separate application for access to the Data. 2.2.6 The RECIPIENT agrees that she/he, and her/his Registered Users, shall not analyse or make any use of the Data in such a way that has the potential to: (i)lead to the re-identification of any Data Subject; or (ii)compromise the anonymity of any Data Subject in any way. 2.2.7 CHARITÉ reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures in countries that have no national laws comparable to that pertaining in the European Economic Area (EEA). 2.3 Data Security 2.3.1 The RECIPIENT agrees that she/he shall take all reasonable security precautions to keep the Data safe, such precautions to be no less onerous than in the applicable German and EU data protection laws and regulations. 2.3.2 The RECIPIENT shall adhere to the principle of IT-Security as set forth in Annex 3 hereto. 3.Provisions of cooperation 3.1 Errors The RECIPIENT agrees to notify CHARITÉ of any errors detected in the Data without undue delay. 3.2 Reissue of data The RECIPIENT accepts that CHARITÉ will reissue Data from time to time, with suitable versioning. If Data is reissued at the request of the Data Subject and/or as he result of other ethical scrutiny, the RECIPIENT agrees to destroy all earlier versions of the Data without undue delay once he has received such information. 3.3 Intellectual property 3.3.1 The RECIPIENT recognises that nothing in this Agreement shall operate to transfer to the RECIPIENT any intellectual property rights in or relating to the Data. 3.3.2 The RECIPIENT does not have the right to sublicense the Data. The RECEPIENT shall inform CHARITÉ about any third party requests for the Data. 3.3.3 The RECIPIENT shall have the right to develop intellectual property based on comparison with their own data. 3.3.4 CHARITÉ has no knowledge of any conflicting property rights of third parties regarding the provided Data. If CHARITÉ learns of potential conflicting property rights of third parties, CHARITÉ shall inform the RECIPIENT; however, no liability can be assumed for this. 3.4 Publications 3.4.1 The RECIPIENT agrees to acknowledge in any RECIPIENT’s work based in whole or part on the Date, any provider publications which encompass and from which Data derive, the respective version of the Data obtained, and the role of CHARITÉ. The RECIPIENT is also entitled to release publications and, in doing so, agrees to acknowledge any of CHARITÉ’s work based in whole or part on the Data in its publication. 3.4.2 The RECIPIENT will also declare in any such work that CHARITÉ and its employees bear no responsibility for the further analysis or interpretation of the Data by the RECIPIENT. 3.5 Liability 3.5.1 The RECIPIENT accepts that CHARITÉ, the original data creators, depositors or copyright holders, or the funders of the Data or any part of the Data supplied: (i)bear no legal responsibility for the accuracy or comprehensiveness of the Data; and (ii)accept no liability for indirect, consequential, or incidental, damages or losses arisingfrom use of the Data, or from the unavailability of, or break in access to, the Data forwhatever reason, except for damages caused intentionally or by gross negligence. 3.5.2 Nothing in this Agreement limits or excludes either Party’s liability for (i) product liability claims, (ii) death or personal injury resulting from negligence or any fraud or (iii) or in case of breaches of so called “material contractual obligations (Kardinalpflichten)”. Material contractual obligations (Kardinalpflichten) are obligations which principally enable the fulfilment of the proper enforcement of the contract and on which the contractual partner can trust and is allowed to trust for compliance (iiii) for any sort of other liability which by law cannot be limited or excluded according to applicable law. 4.General provisions 4.1 Termination of Agreement 4.1.1 This Agreement shall expire automatically three years after its signature by both PARTIES. 4.1.2 This Agreement will terminate immediately upon any breach of the provisions of this Agreement by the RECIPIENT. 4.1.3 The RECIPIENT accepts that the changing ethical framework of human genetic research may lead to: (i)alteration to the provisions of this Agreement, in which case the RECIPIENT may accept such alterations or terminate this Agreement; or (ii) the withdrawal of this Agreement in extreme circumstances.4.1.4 The notification of either PARTY to terminate this Agreement shall be made in writing with 4 weeks’ notice. 4.1.5 In the event that this Agreement is expired or terminated in accordance with this Clause 4.1 the RECIPIENT shall destroy all Data at the direction of CHARITÉ. This shall not apply to the extent that Data is saved in automatic back-up systems for which destruction shall follow the regular process of such back-up system, however, such Data shall be eliminated within a period of 90 days after the date of termination. Upon request of CHARITÉ, the RECIPIENT will certify the destruction of the Data. 4.2 Applicable Law 4.2.1 This Agreement shall be governed, construed and interpreted in accordance with the substantive laws of Germany. This Agreement shall be in the English language and the English version of this Agreement shall be deemed the official and governing instrument, notwithstanding any translations thereof. 4.2.2 The PARTIES agree to submit to the exclusive jurisdiction of the courts of Berlin, Germany, as regards any disputes, claims or matter arising under this Agreement. Annexes Annex 1 Application for Access to Genotype Data Annex 2 Declaration of commitment Annex 3 Data Security SIGNATURES for CHARITÉ ______________________ ______________________ Place, date, Anne Großkopff, Business Director Faculty for RECIPIENT ______________________ _____________________ Place, date, [Name ... ] Annex 1 Application for Access to Genotype Data Name of RECIPIENT and registered USERS, including affiliations and contact details. Enter the primary email correspondence email address you would like to use: [...] Please ensure that a full postal and email address is included for the RECIPIENT and each registered USER. [...] Title of Project (in less than 30 words) [...] Data Request [...] Research Question Please provide a clear description of the project and its specific aims in no more than 750 words. This should include specific details of what you plan to do with the data and include key references. [...] Feasibiliy Please describe fully your experience and expertise, and that of your collaborators, and how this will be applied to the proposed study. [...] Please send completed forms to: Charité - Universitätsmedizin Berlin BIH Digital Health Center Prof. Dr. Roland Eils Kapelle-Ufer 2 10117 Berlin Germany Email: Annex 2 Declaration of Commitment Please send signed form to: Charité - Universitätsmedizin Berlin BIH Digital Health Center Prof. Dr. Roland Eils Kapelle-Ufer 2 10117 Berlin Germany Email: I, __________________________________, declare that I will comply with the requirements of the Data Transfer Agreement as agreed upon between CHARITÉ and the RECIPIENT, including but not limited to the requirements of the applicable data protection regulations. With my signature I confirm the receipt of a copy of this agreement. ______________________ ______________________ [Place, date, name] Annex 3 Principle of IT-Security An appropriate level of data protection shall be ensured through appropriate technical and organisational measures: Guarantee of confidentiality Admission control No unauthorised access to data processing equipment, e.g: magnetic or chip cards, keys, electric door openers, plant security or gatekeepers, alarm systems, video systems Access control No unauthorized system use, e.g: (secure) passwords, automatic locking mechanisms, two-factor authentication, encryption of data carriers No unauthorized reading, copying, modification or removal within the system, e.g: authorization concepts and need-based access rights, logging of accesses Guarantee of integrity Transmission control No unauthorized reading, copying, modification or removal during electronic transmission or transport, e.g: encryption, Virtual Private Networks (VPN), electronic signature Input control Determination whether and by whom personal data have been entered, modified or removed from data processing systems, e.g: logging, document management Guarantee of the availability and resilience of the system Availability control Protection against accidental or deliberate destruction or loss, e.g: Backup strategy (online/offline; on-site/off-site), uninterruptible power supply (UPS), virus protection, firewall, reporting channels and emergency plans Rapid recoverability Procedures for regular review, assessment and evaluation Data protection management Incident response management Privacy friendly default settings The implementation shall take into account the state of the art, implementation costs and the nature, scale and purposes of the processing, as well as the varying degrees of probability and seriousness of the risk to the rights and freedoms of natural persons. The technical and organisational measures are subject to technical progress and further development.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004481 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00004150095 fastq.gz 13.2 GB
EGAF00004150096 fastq.gz 31.2 GB
EGAF00004150097 fastq.gz 5.9 GB
EGAF00004150098 fastq.gz 13.8 GB
EGAF00004150099 fastq.gz 6.8 GB
EGAF00004150100 fastq.gz 15.9 GB
EGAF00004150101 fastq.gz 10.1 GB
EGAF00004150102 fastq.gz 23.8 GB
EGAF00004150103 fastq.gz 3.3 GB
EGAF00004150104 fastq.gz 7.1 GB
EGAF00004150105 fastq.gz 6.8 GB
EGAF00004150106 fastq.gz 15.7 GB
EGAF00004150107 fastq.gz 9.9 GB
EGAF00004150108 fastq.gz 23.5 GB
EGAF00004150109 fastq.gz 7.1 GB
EGAF00004150110 fastq.gz 16.7 GB
EGAF00004150111 fastq.gz 6.5 GB
EGAF00004150112 fastq.gz 15.0 GB
EGAF00004150113 fastq.gz 7.7 GB
EGAF00004150114 fastq.gz 18.1 GB
EGAF00004150115 fastq.gz 10.8 GB
EGAF00004150116 fastq.gz 25.5 GB
EGAF00004150117 fastq.gz 6.5 GB
EGAF00004150118 fastq.gz 15.2 GB
EGAF00004150119 fastq.gz 8.7 GB
EGAF00004150120 fastq.gz 20.0 GB
EGAF00004150121 fastq.gz 10.1 GB
EGAF00004150122 fastq.gz 23.2 GB
EGAF00004150123 fastq.gz 3.8 GB
EGAF00004150124 fastq.gz 8.8 GB
EGAF00004150125 fastq.gz 4.2 GB
EGAF00004150126 fastq.gz 9.7 GB
EGAF00004150127 fastq.gz 2.7 GB
EGAF00004150128 fastq.gz 6.2 GB
EGAF00004150129 fastq.gz 3.7 GB
EGAF00004150130 fastq.gz 8.2 GB
EGAF00004150131 fastq.gz 3.3 GB
EGAF00004150132 fastq.gz 7.7 GB
EGAF00004150133 fastq.gz 3.6 GB
EGAF00004150134 fastq.gz 8.7 GB
EGAF00004150135 fastq.gz 4.1 GB
EGAF00004150136 fastq.gz 9.4 GB
EGAF00004150137 fastq.gz 3.9 GB
EGAF00004150138 fastq.gz 8.4 GB
EGAF00004150139 fastq.gz 7.5 GB
EGAF00004150140 fastq.gz 17.6 GB
EGAF00004150141 fastq.gz 6.5 GB
EGAF00004150142 fastq.gz 15.0 GB
EGAF00004150143 fastq.gz 7.6 GB
EGAF00004150144 fastq.gz 18.0 GB
EGAF00004150145 fastq.gz 4.7 GB
EGAF00004150146 fastq.gz 10.8 GB
EGAF00004150147 fastq.gz 4.6 GB
EGAF00004150148 fastq.gz 10.6 GB
EGAF00004150149 fastq.gz 5.0 GB
EGAF00004150150 fastq.gz 11.4 GB
EGAF00004150151 fastq.gz 4.5 GB
EGAF00004150152 fastq.gz 9.8 GB
EGAF00004150153 fastq.gz 3.7 GB
EGAF00004150154 fastq.gz 8.5 GB
EGAF00004150155 fastq.gz 4.4 GB
EGAF00004150156 fastq.gz 9.3 GB
EGAF00004150157 fastq.gz 4.7 GB
EGAF00004150158 fastq.gz 10.2 GB
EGAF00004150159 fastq.gz 3.6 GB
EGAF00004150160 fastq.gz 7.9 GB
EGAF00004150161 fastq.gz 3.9 GB
EGAF00004150162 fastq.gz 8.5 GB
EGAF00004150163 fastq.gz 4.6 GB
EGAF00004150164 fastq.gz 9.8 GB
EGAF00004150165 fastq.gz 4.3 GB
EGAF00004150166 fastq.gz 9.1 GB
EGAF00004150167 fastq.gz 12.9 GB
EGAF00004150168 fastq.gz 30.5 GB
EGAF00004150169 fastq.gz 5.9 GB
EGAF00004150170 fastq.gz 13.6 GB
EGAF00004150171 fastq.gz 6.7 GB
EGAF00004150172 fastq.gz 15.6 GB
EGAF00004150173 fastq.gz 10.0 GB
EGAF00004150174 fastq.gz 23.3 GB
EGAF00004150175 fastq.gz 3.3 GB
EGAF00004150176 fastq.gz 7.3 GB
EGAF00004150177 fastq.gz 6.6 GB
EGAF00004150178 fastq.gz 15.4 GB
EGAF00004150179 fastq.gz 9.8 GB
EGAF00004150180 fastq.gz 23.1 GB
EGAF00004150181 fastq.gz 7.0 GB
EGAF00004150182 fastq.gz 16.4 GB
EGAF00004150183 fastq.gz 6.4 GB
EGAF00004150184 fastq.gz 14.8 GB
EGAF00004150185 fastq.gz 7.7 GB
EGAF00004150186 fastq.gz 17.8 GB
EGAF00004150187 fastq.gz 10.6 GB
EGAF00004150188 fastq.gz 25.0 GB
EGAF00004150189 fastq.gz 6.4 GB
EGAF00004150190 fastq.gz 14.9 GB
EGAF00004150191 fastq.gz 8.6 GB
EGAF00004150192 fastq.gz 19.6 GB
EGAF00004150193 fastq.gz 9.9 GB
EGAF00004150194 fastq.gz 22.8 GB
EGAF00004150195 fastq.gz 4.0 GB
EGAF00004150196 fastq.gz 9.1 GB
EGAF00004150197 fastq.gz 4.1 GB
EGAF00004150198 fastq.gz 9.5 GB
EGAF00004150199 fastq.gz 2.8 GB
EGAF00004150200 fastq.gz 6.4 GB
EGAF00004150201 fastq.gz 3.9 GB
EGAF00004150202 fastq.gz 8.6 GB
EGAF00004150203 fastq.gz 3.5 GB
EGAF00004150204 fastq.gz 8.0 GB
EGAF00004150205 fastq.gz 3.8 GB
EGAF00004150206 fastq.gz 9.1 GB
EGAF00004150207 fastq.gz 4.2 GB
EGAF00004150208 fastq.gz 9.8 GB
EGAF00004150209 fastq.gz 4.0 GB
EGAF00004150210 fastq.gz 8.8 GB
EGAF00004150211 fastq.gz 7.3 GB
EGAF00004150212 fastq.gz 17.1 GB
EGAF00004150213 fastq.gz 6.3 GB
EGAF00004150214 fastq.gz 14.6 GB
EGAF00004150215 fastq.gz 7.4 GB
EGAF00004150216 fastq.gz 17.5 GB
EGAF00004150217 fastq.gz 4.7 GB
EGAF00004150218 fastq.gz 11.0 GB
EGAF00004150219 fastq.gz 4.6 GB
EGAF00004150220 fastq.gz 10.7 GB
EGAF00004150221 fastq.gz 5.1 GB
EGAF00004150222 fastq.gz 11.6 GB
EGAF00004150223 fastq.gz 4.5 GB
EGAF00004150224 fastq.gz 9.9 GB
EGAF00004150225 fastq.gz 3.8 GB
EGAF00004150226 fastq.gz 8.6 GB
EGAF00004150227 fastq.gz 4.5 GB
EGAF00004150228 fastq.gz 9.4 GB
EGAF00004150229 fastq.gz 4.8 GB
EGAF00004150230 fastq.gz 10.4 GB
EGAF00004150231 fastq.gz 3.6 GB
EGAF00004150232 fastq.gz 7.9 GB
EGAF00004150233 fastq.gz 4.0 GB
EGAF00004150234 fastq.gz 8.6 GB
EGAF00004150235 fastq.gz 4.6 GB
EGAF00004150236 fastq.gz 9.8 GB
EGAF00004150237 fastq.gz 4.3 GB
EGAF00004150238 fastq.gz 9.2 GB
EGAF00004150239 fastq.gz 5.7 GB
EGAF00004150240 fastq.gz 13.4 GB
EGAF00004150241 fastq.gz 6.6 GB
EGAF00004150242 fastq.gz 15.4 GB
EGAF00004150243 fastq.gz 3.3 GB
EGAF00004150244 fastq.gz 7.4 GB
EGAF00004150245 fastq.gz 6.5 GB
EGAF00004150246 fastq.gz 15.2 GB
EGAF00004150247 fastq.gz 6.8 GB
EGAF00004150248 fastq.gz 16.2 GB
EGAF00004150249 fastq.gz 6.3 GB
EGAF00004150250 fastq.gz 14.6 GB
EGAF00004150251 fastq.gz 7.5 GB
EGAF00004150252 fastq.gz 17.6 GB
EGAF00004150253 fastq.gz 6.3 GB
EGAF00004150254 fastq.gz 14.7 GB
EGAF00004150255 fastq.gz 4.1 GB
EGAF00004150256 fastq.gz 9.2 GB
EGAF00004150257 fastq.gz 2.9 GB
EGAF00004150258 fastq.gz 6.5 GB
EGAF00004150259 fastq.gz 4.0 GB
EGAF00004150260 fastq.gz 8.8 GB
EGAF00004150261 fastq.gz 3.5 GB
EGAF00004150262 fastq.gz 8.1 GB
EGAF00004150263 fastq.gz 3.9 GB
EGAF00004150264 fastq.gz 9.1 GB
EGAF00004150265 fastq.gz 4.2 GB
EGAF00004150266 fastq.gz 9.8 GB
EGAF00004150267 fastq.gz 4.1 GB
EGAF00004150268 fastq.gz 9.0 GB
EGAF00004150269 fastq.gz 4.8 GB
EGAF00004150270 fastq.gz 11.1 GB
EGAF00004150271 fastq.gz 4.7 GB
EGAF00004150272 fastq.gz 10.8 GB
EGAF00004150273 fastq.gz 5.1 GB
EGAF00004150274 fastq.gz 11.7 GB
EGAF00004150275 fastq.gz 4.6 GB
EGAF00004150276 fastq.gz 10.0 GB
EGAF00004150277 fastq.gz 3.8 GB
EGAF00004150278 fastq.gz 8.7 GB
EGAF00004150279 fastq.gz 4.8 GB
EGAF00004150280 fastq.gz 10.5 GB
EGAF00004150281 fastq.gz 5.8 GB
EGAF00004150282 fastq.gz 13.5 GB
EGAF00004150283 fastq.gz 6.7 GB
EGAF00004150284 fastq.gz 15.5 GB
EGAF00004150285 fastq.gz 3.3 GB
EGAF00004150286 fastq.gz 7.3 GB
EGAF00004150287 fastq.gz 6.6 GB
EGAF00004150288 fastq.gz 15.3 GB
EGAF00004150289 fastq.gz 6.9 GB
EGAF00004150290 fastq.gz 16.3 GB
EGAF00004150291 fastq.gz 6.4 GB
EGAF00004150292 fastq.gz 14.6 GB
EGAF00004150293 fastq.gz 7.6 GB
EGAF00004150294 fastq.gz 17.7 GB
EGAF00004150295 fastq.gz 6.4 GB
EGAF00004150296 fastq.gz 14.8 GB
EGAF00004150297 fastq.gz 4.0 GB
EGAF00004150298 fastq.gz 9.2 GB
EGAF00004150299 fastq.gz 2.9 GB
EGAF00004150300 fastq.gz 6.5 GB
EGAF00004150301 fastq.gz 4.0 GB
EGAF00004150302 fastq.gz 8.7 GB
EGAF00004150303 fastq.gz 3.5 GB
EGAF00004150304 fastq.gz 8.1 GB
EGAF00004150305 fastq.gz 3.9 GB
EGAF00004150306 fastq.gz 9.2 GB
EGAF00004150307 fastq.gz 4.2 GB
EGAF00004150308 fastq.gz 9.8 GB
EGAF00004150309 fastq.gz 4.1 GB
EGAF00004150310 fastq.gz 8.9 GB
EGAF00004150311 fastq.gz 4.7 GB
EGAF00004150312 fastq.gz 10.8 GB
EGAF00004150313 fastq.gz 4.6 GB
EGAF00004150314 fastq.gz 10.5 GB
EGAF00004150315 fastq.gz 5.0 GB
EGAF00004150316 fastq.gz 11.3 GB
EGAF00004150317 fastq.gz 4.6 GB
EGAF00004150318 fastq.gz 10.0 GB
EGAF00004150319 fastq.gz 3.8 GB
EGAF00004150320 fastq.gz 8.6 GB
EGAF00004150321 fastq.gz 4.8 GB
EGAF00004150322 fastq.gz 10.4 GB
228 Files (2.1 TB)