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Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma

Genomic analysis between pre-invasive and invasive components of malignant pulmonary nodule (MPN) facilitates the description of lung adenocarcinoma (LUAD) evolutionary patterns. We conduct an analysis of gene-panel sequencing on 53 T1 stage LUAD cases, which extend the understanding of evolutionary trajectories during invasiveness acquisition in early LUAD.

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This agreement governs the terms on which access will be granted to the genotype data generated by Nanjing Medical University Affiliated Jiangsu Cancer Hospital

DATA ACCESS AGREEMENT 1. You agree to use the Data only for the advancement of medical research, according to the consent obtained from sample donors. 2. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 3. You agree not to attempt to link the data provided under this agreement to other information or archive data available for the data sets provided, even if access to that data has been formally granted to you, or it is freely available without restriction, without specific permission being sought from the relevent access committees. 4. You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others, except as necessary for data/safety monitoring or programme management. Should You wish to share the Data with a collaborator out with the same Institution, the third party must make a separate application for access to the Data. 5. You agree to use the data for the approved purpose and project described in your application; use of the data for a new purpose or project will require a new application and approval. 6. You accept that Data will be reissued from time to time, with suitable versioning. If the reissue is at the request of sample donors and/or other ethical scrutiny, You will destroy earlier versions of the Data. 7. You accept that the Consortium, the original data creators, depositors or copyright holders, or the funders of the Data or any part of the Data supplied: a) bear no legal responsibility for the accuracy or comprehensiveness of the Data; and b) accept no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason. 8. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted. 9. You recognise that nothing in this agreement shall operate to transfer to the User Institution any intellectual property rights relating to the Data. The User Institution has the right to develop intellectual property based on comparisons with their own data. 10. You accept that this agreement will terminate immediately upon any breach of this agreement by You and You will be required to destroy any Data held. 11. You accept that it may be necessary for the Consortium or its appointed agent to alter the terms of this agreement from time to time in order to address new concerns. In this event, the Consortium or its appointed agent will contact You to inform You of any changes and You agree that Your continued use of the Data shall be dependent on the parties entering into a new version of the Agreement. 12. You agree that you will submit a report to the Consortium Data Access Committee, if requested, on completion of the agreed purpose. The Consortium Data Access Committee agrees to treat the report and all information, data, results, and conclusions contained within such report as confidential information belonging to the User Institution.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004754 Other
ID File Type Size Located in
EGAF00004724750 vcf 7.7 MB
EGAF00004724751 vcf 9.2 MB
EGAF00004724752 vcf 3.4 MB
EGAF00004724753 vcf 3.9 MB
EGAF00004724754 vcf 3.8 MB
EGAF00004724755 vcf 3.2 MB
EGAF00004724756 vcf 3.2 MB
EGAF00004724757 vcf 16.5 MB
EGAF00004724758 vcf 3.0 MB
EGAF00004724759 vcf 9.9 MB
EGAF00004724760 vcf 11.6 MB
EGAF00004724761 vcf 8.5 MB
EGAF00004724762 vcf 9.0 MB
EGAF00004724763 vcf 2.6 MB
EGAF00004724764 vcf 19.5 MB
EGAF00004724765 vcf 17.9 MB
EGAF00004724766 vcf 11.3 MB
EGAF00004724767 vcf 8.5 MB
EGAF00004724768 vcf 6.4 MB
EGAF00004724769 vcf 7.1 MB
EGAF00004724770 vcf 9.0 MB
EGAF00004724771 vcf 6.1 MB
EGAF00004724772 vcf 8.6 MB
EGAF00004724773 vcf 8.4 MB
EGAF00004724774 vcf 8.3 MB
EGAF00004724775 vcf 9.2 MB
EGAF00004724776 vcf 9.3 MB
EGAF00004724777 vcf 7.6 MB
EGAF00004724778 vcf 8.4 MB
EGAF00004724779 vcf 7.5 MB
EGAF00004724780 vcf 7.8 MB
EGAF00004724781 vcf 4.0 MB
EGAF00004724782 vcf 2.1 MB
EGAF00004724783 vcf 1.9 MB
EGAF00004724784 vcf 6.5 MB
EGAF00004724785 vcf 5.1 MB
EGAF00004724786 vcf 8.3 MB
EGAF00004724787 vcf 6.3 MB
EGAF00004724788 vcf 5.4 MB
EGAF00004724789 vcf 9.7 MB
EGAF00004724790 vcf 7.8 MB
EGAF00004724791 vcf 6.9 MB
EGAF00004724792 vcf 7.9 MB
EGAF00004724793 vcf 4.7 MB
EGAF00004724794 vcf 9.1 MB
EGAF00004724795 vcf 3.7 MB
EGAF00004724796 vcf 6.7 MB
EGAF00004724797 vcf 4.4 MB
EGAF00004724798 vcf 4.4 MB
EGAF00004724799 vcf 2.3 MB
EGAF00004724800 vcf 5.5 MB
EGAF00004724801 vcf 6.3 MB
EGAF00004724802 vcf 6.3 MB
EGAF00004724803 vcf 5.2 MB
EGAF00004724804 vcf 15.8 MB
EGAF00004724805 vcf 6.1 MB
EGAF00004724806 vcf 5.0 MB
EGAF00004724807 vcf 3.6 MB
EGAF00004724808 vcf 3.6 MB
EGAF00004724809 vcf 4.5 MB
EGAF00004724810 vcf 13.7 MB
EGAF00004724811 vcf 4.6 MB
EGAF00004724812 vcf 4.8 MB
EGAF00004724813 vcf 4.5 MB
EGAF00004724814 vcf 7.6 MB
EGAF00004724815 vcf 3.4 MB
EGAF00004724816 vcf 6.1 MB
EGAF00004724817 vcf 7.4 MB
EGAF00004724818 vcf 7.3 MB
EGAF00004724819 vcf 4.8 MB
EGAF00004724820 vcf 6.8 MB
EGAF00004724821 vcf 3.7 MB
EGAF00004724822 vcf 3.0 MB
EGAF00004724823 vcf 4.1 MB
EGAF00004724824 vcf 5.5 MB
EGAF00004724825 vcf 6.4 MB
EGAF00004724826 vcf 4.9 MB
EGAF00004724827 vcf 5.0 MB
EGAF00004724828 vcf 6.4 MB
EGAF00004724829 vcf 3.2 MB
EGAF00004724830 vcf 5.5 MB
EGAF00004724831 vcf 2.6 MB
EGAF00004724832 vcf 5.7 MB
EGAF00004724833 vcf 7.2 MB
EGAF00004724834 vcf 8.7 MB
EGAF00004724835 vcf 5.9 MB
EGAF00004724836 vcf 8.2 MB
EGAF00004724837 vcf 4.7 MB
EGAF00004724838 vcf 5.9 MB
EGAF00004724839 vcf 6.6 MB
EGAF00004724840 vcf 5.2 MB
EGAF00004724841 vcf 6.9 MB
EGAF00004724842 vcf 6.4 MB
EGAF00004724843 vcf 3.6 MB
EGAF00004724844 vcf 4.7 MB
EGAF00004724845 vcf 4.1 MB
EGAF00004724846 vcf 4.6 MB
EGAF00004724847 vcf 5.5 MB
EGAF00004724848 vcf 7.2 MB
EGAF00004724849 vcf 3.9 MB
EGAF00004724850 vcf 4.8 MB
EGAF00004724851 vcf 6.7 MB
EGAF00004724852 vcf 6.6 MB
EGAF00004724853 vcf 3.4 MB
EGAF00004724854 vcf 6.0 MB
EGAF00004724855 vcf 5.7 MB
EGAF00004724856 vcf 7.4 MB
EGAF00004724857 vcf 5.3 MB
EGAF00004724858 vcf 6.2 MB
EGAF00004724859 vcf 4.9 MB
EGAF00004724860 vcf 1.1 MB
EGAF00004724861 vcf 496.0 kB
EGAF00004724862 vcf 5.7 MB
EGAF00004724863 vcf 901.6 kB
EGAF00004724864 vcf 6.9 MB
EGAF00004724865 vcf 6.1 MB
EGAF00004724866 vcf 5.0 MB
EGAF00004724867 vcf 2.9 MB
EGAF00004724868 vcf 1.8 MB
EGAF00004724869 vcf 5.2 MB
EGAF00004724870 vcf 3.9 MB
EGAF00004724871 vcf 5.0 MB
EGAF00004724872 vcf 2.5 MB
EGAF00004724873 vcf 7.0 MB
EGAF00004724874 vcf 2.5 MB
EGAF00004724875 vcf 4.6 MB
EGAF00004724876 vcf 6.5 MB
EGAF00004724877 vcf 5.7 MB
EGAF00004724878 vcf 4.4 MB
EGAF00004724879 vcf 3.7 MB
EGAF00004724880 vcf 7.1 MB
EGAF00004724881 vcf 6.1 MB
EGAF00004724882 vcf 7.9 MB
EGAF00004724883 vcf 5.5 MB
EGAF00004724884 vcf 8.0 MB
EGAF00004724885 vcf 8.4 MB
EGAF00004724886 vcf 3.8 MB
EGAF00004724887 vcf 4.4 MB
EGAF00004724888 vcf 4.1 MB
EGAF00004724889 vcf 7.9 MB
EGAF00004724890 vcf 2.6 MB
EGAF00004724891 vcf 6.7 MB
EGAF00004724892 vcf 5.1 MB
EGAF00004724893 vcf 3.6 MB
EGAF00004724894 vcf 2.2 MB
EGAF00004724895 vcf 5.4 MB
EGAF00004724896 vcf 6.7 MB
EGAF00004724897 vcf 7.5 MB
EGAF00004724898 vcf 6.5 MB
EGAF00004724899 vcf 4.1 MB
EGAF00004724900 vcf 6.3 MB
EGAF00004724901 vcf 10.6 MB
EGAF00004724902 vcf 4.9 MB
EGAF00004724903 vcf 5.2 MB
EGAF00004724904 vcf 7.0 MB
EGAF00004724905 vcf 3.3 MB
EGAF00004724906 vcf 5.7 MB
EGAF00004724907 vcf 6.0 MB
EGAF00004724908 vcf 15.7 MB
EGAF00004724909 vcf 16.8 MB
EGAF00004724910 vcf 8.0 MB
EGAF00004724911 vcf 8.1 MB
EGAF00004724912 vcf 8.5 MB
EGAF00004724913 vcf 6.8 MB
EGAF00004724914 vcf 6.8 MB
EGAF00004724915 vcf 7.3 MB
EGAF00004724916 vcf 14.9 MB
EGAF00004724917 vcf 15.7 MB
EGAF00004724918 vcf 9.3 MB
EGAF00004724919 vcf 6.8 MB
EGAF00004724920 vcf 6.9 MB
EGAF00004724921 vcf 7.6 MB
EGAF00004724922 vcf 8.1 MB
EGAF00004724923 vcf 4.2 MB
174 Files (1.1 GB)