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ScRNA-seq of PBMC and whole blood samples reveales a dysregulated myeloid cell compartment in severe COVID-19

In a dual-center, two-cohort study, we performed single-cell RNA-sequencing of whole blood and peripheral blood mononuclear cells to determine changes in immune cell composition and activation in mild vs. severe COVID-19 over time. This study provides detailed insights into the systemic immune response to SARS-CoV-2 infection and reveals profound alterations in the myeloid cell compartment associated with severe COVID-19.

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Data access policy for Schulte-Schrepping et al., 2020: Severe COVID-19 is marked by a dysregulated myeloid cell compartment

Access to data generated is made available by completing the data access agreement for review by the data access committee and will be granted exclusively to qualified investigators for appropriate use.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004571 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00004824525 fastq.gz 23.3 GB Report
EGAF00004824526 fastq.gz 1.1 GB Report
EGAF00004824527 fastq.gz 999.6 MB Report
EGAF00004824528 fastq.gz 540.4 MB Report
EGAF00004824529 fastq.gz 10.1 GB Report
EGAF00004824530 fastq.gz 24.0 GB Report
EGAF00004824531 fastq.gz 10.1 GB Report
EGAF00004824532 fastq.gz 9.9 GB Report
EGAF00004824533 fastq.gz 500.6 MB Report
EGAF00004824534 fastq.gz 23.9 GB Report
EGAF00004824535 fastq.gz 9.8 GB Report
EGAF00004824536 fastq.gz 1.1 GB Report
EGAF00004824537 fastq.gz 998.2 MB Report
EGAF00004824538 fastq.gz 501.8 MB Report
EGAF00004824539 fastq.gz 23.2 GB Report
EGAF00004824540 fastq.gz 542.0 MB Report
EGAF00004824541 fastq.gz 43.8 GB Report
EGAF00004824542 fastq.gz 17.7 GB Report
EGAF00004824543 fastq.gz 1.4 GB Report
EGAF00004824544 fastq.gz 41.6 GB Report
EGAF00004824545 fastq.gz 692.8 MB Report
EGAF00004824546 fastq.gz 18.7 GB Report
EGAF00004824547 fastq.gz 15.4 GB Report
EGAF00004824548 fastq.gz 718.7 MB Report
EGAF00004824549 fastq.gz 14.9 GB Report
EGAF00004824550 fastq.gz 758.4 MB Report
EGAF00004824551 fastq.gz 545.8 MB Report
EGAF00004824552 fastq.gz 572.6 MB Report
EGAF00004824553 fastq.gz 25.8 GB Report
EGAF00004824554 fastq.gz 24.9 GB Report
EGAF00004824555 fastq.gz 4.9 GB Report
EGAF00004824556 fastq.gz 4.7 GB Report
EGAF00004824557 fastq.gz 11.4 GB Report
EGAF00004824558 fastq.gz 5.1 GB Report
EGAF00004824559 fastq.gz 11.4 GB Report
EGAF00004824560 fastq.gz 4.9 GB Report
EGAF00004824561 fastq.gz 451.3 MB Report
EGAF00004824562 fastq.gz 226.4 MB Report
EGAF00004824563 fastq.gz 10.9 GB Report
EGAF00004824564 fastq.gz 421.7 MB Report
EGAF00004824565 fastq.gz 12.0 GB Report
EGAF00004824566 fastq.gz 212.1 MB Report
EGAF00004827389 csv 65.8 kB
EGAF00004827405 fastq.gz 412.1 MB Report
EGAF00004827406 fastq.gz 7.3 GB Report
EGAF00004827407 fastq.gz 12.7 GB Report
EGAF00004827408 fastq.gz 420.4 MB Report
EGAF00004827409 fastq.gz 511.6 MB Report
EGAF00004827410 fastq.gz 12.9 GB Report
EGAF00004827411 fastq.gz 501.0 MB Report
EGAF00004827412 fastq.gz 7.2 GB Report
EGAF00004827413 fastq.gz 5.1 GB Report
EGAF00004827414 fastq.gz 11.9 GB Report
EGAF00004827415 fastq.gz 5.3 GB Report
EGAF00004827416 fastq.gz 222.7 MB Report
EGAF00004827417 fastq.gz 12.5 GB Report
EGAF00004827418 fastq.gz 436.5 MB Report
EGAF00004827419 fastq.gz 30.9 GB Report
EGAF00004827420 fastq.gz 39.8 GB Report
EGAF00004827421 fastq.gz 33.5 GB Report
EGAF00004827422 fastq.gz 43.2 GB Report
EGAF00004827423 fastq.gz 35.0 GB Report
EGAF00004827424 fastq.gz 43.9 GB Report
EGAF00004827425 fastq.gz 36.5 GB Report
EGAF00004827426 fastq.gz 45.4 GB Report
EGAF00004827427 fastq.gz 31.6 GB Report
EGAF00004827428 fastq.gz 39.6 GB Report
EGAF00004827429 fastq.gz 36.8 GB Report
EGAF00004827430 fastq.gz 45.2 GB Report
EGAF00004827431 fastq.gz 23.7 GB Report
EGAF00004827432 fastq.gz 33.2 GB Report
EGAF00004827433 fastq.gz 12.9 GB Report
EGAF00004827434 fastq.gz 17.6 GB Report
EGAF00004829311 fastq.gz 37.1 GB Report
EGAF00004829312 fastq.gz 48.1 GB Report
EGAF00004829313 fastq.gz 39.8 GB Report
EGAF00004829314 fastq.gz 51.1 GB Report
EGAF00004829315 fastq.gz 35.0 GB Report
EGAF00004829316 fastq.gz 44.2 GB Report
EGAF00004829317 fastq.gz 31.7 GB Report
EGAF00004829318 fastq.gz 40.7 GB Report
EGAF00004829319 fastq.gz 18.2 GB Report
EGAF00004829320 fastq.gz 27.1 GB Report
EGAF00004829321 fastq.gz 31.1 GB Report
EGAF00004829322 fastq.gz 46.6 GB Report
EGAF00004829323 fastq.gz 18.3 GB Report
EGAF00004829324 fastq.gz 25.2 GB Report
EGAF00004829325 fastq.gz 11.5 GB Report
EGAF00004829326 fastq.gz 15.6 GB Report
EGAF00004829327 fastq.gz 41.4 GB Report
EGAF00004829328 fastq.gz 53.5 GB Report
EGAF00004829329 fastq.gz 40.3 GB Report
EGAF00004829330 fastq.gz 52.4 GB Report
EGAF00004829331 fastq.gz 31.4 GB Report
EGAF00004829332 fastq.gz 38.5 GB Report
EGAF00004829333 fastq.gz 34.2 GB Report
EGAF00004829334 fastq.gz 42.7 GB Report
97 Files (1.9 TB)