ScRNA-seq of PBMC and whole blood samples reveales a dysregulated myeloid cell compartment in severe COVID-19

Dataset ID Technology Samples
EGAD00001006550 Illumina NovaSeq 6000 141

Dataset Description

In a dual-center, two-cohort study, we performed single-cell RNA-sequencing of whole blood and peripheral blood mononuclear cells to determine changes in immune cell composition and activation in mild vs. severe COVID-19 over time. This study provides detailed insights into the systemic immune response to SARS-CoV-2 infection and reveals profound alterations in the myeloid cell compartment associated with severe COVID-19.

Who controls access to this dataset

For each dataset that requires controlled access, there is a corresponding Data Access Committee (DAC) who determine access permissions. Access to actual data files is not managed by the EGA. If you need to request access to this data set, please contact:

Data Access Commitee for Schulte-Schrepping et al., 2020: Severe COVID-19 is marked by a dysregulated myeloid cell compartment
Contact person: Joachim L. Schultze
Email: j [dot] schultze [at] uni-bonn [dot] de
More details: EGAC00001001684


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