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Chracterising cellur pathways underlying CD3/CD28 activation of human CD4+ cells

We devised an approach to disentangle the TCR and CD28 pathways upon stimulation in naive and memory primary human CD4+ T cells (Tcons) in response to defined stimulatory signals. Sorted Tcons were activated using a titration of anti-CD3 and anti-CD28 in combination as well as individually. As a control we cultured cells in the same conditions but without the stimuli. In total, we defined seven conditions from four individuals for sequencing. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/.

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Study ID Study Title Study Type
EGAS00001002438 Transcriptome Analysis
ID File Type Size Located in
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EGAF00004854242 cram 140.2 MB
EGAF00004854243 cram 141.4 MB
EGAF00004854244 cram 132.9 MB
EGAF00004854245 cram 148.7 MB
EGAF00004854246 cram 169.0 MB
EGAF00004854247 cram 149.7 MB
EGAF00004854248 cram 149.8 MB
EGAF00004854249 cram 155.6 MB
EGAF00004854250 cram 147.0 MB
EGAF00004854251 cram 141.0 MB
EGAF00004854252 cram 145.5 MB
EGAF00004854253 cram 155.4 MB
EGAF00004854254 cram 170.9 MB
EGAF00004854255 cram 158.0 MB
EGAF00004854256 cram 168.8 MB
EGAF00004854257 cram 144.8 MB
EGAF00004854258 cram 148.7 MB
EGAF00004854259 cram 145.8 MB
EGAF00004854260 cram 164.0 MB
EGAF00004854261 cram 132.7 MB
EGAF00004854262 cram 175.4 MB
EGAF00004854263 cram 144.2 MB
EGAF00004854264 cram 165.9 MB
EGAF00004854265 cram 168.6 MB
EGAF00004854266 cram 165.1 MB
EGAF00004854267 cram 148.4 MB
EGAF00004854268 cram 142.9 MB
EGAF00004854269 cram 141.1 MB
EGAF00004854270 cram 156.2 MB
EGAF00004854271 cram 166.5 MB
EGAF00004854272 cram 166.2 MB
EGAF00004854273 cram 172.0 MB
EGAF00004854274 cram 150.3 MB
EGAF00004854275 cram 149.5 MB
EGAF00004854276 cram 160.0 MB
EGAF00004854277 cram 156.6 MB
EGAF00004854278 cram 193.3 MB
EGAF00004854279 cram 143.8 MB
EGAF00004854280 cram 168.8 MB
EGAF00004854281 cram 168.8 MB
EGAF00004854282 cram 175.6 MB
EGAF00004854283 cram 141.8 MB
EGAF00004854284 cram 149.2 MB
EGAF00004854285 cram 156.3 MB
EGAF00004854286 cram 159.8 MB
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EGAF00004854289 cram 168.9 MB
EGAF00004854290 cram 164.8 MB
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EGAF00004854292 cram 164.2 MB
EGAF00004854293 cram 147.4 MB
EGAF00004854294 cram 152.7 MB
EGAF00004854295 cram 148.3 MB
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EGAF00004854297 cram 148.8 MB
EGAF00004854298 cram 140.4 MB
EGAF00004854299 cram 142.2 MB
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EGAF00004854303 cram 150.2 MB
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EGAF00004854307 cram 141.9 MB
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EGAF00004854311 cram 158.1 MB
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EGAF00004854316 cram 164.5 MB
EGAF00004854317 cram 133.2 MB
EGAF00004854318 cram 175.3 MB
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EGAF00004854320 cram 166.6 MB
EGAF00004854321 cram 168.8 MB
EGAF00004854322 cram 165.5 MB
EGAF00004854323 cram 149.1 MB
EGAF00004854324 cram 143.2 MB
EGAF00004854325 cram 141.6 MB
EGAF00004854326 cram 157.1 MB
EGAF00004854327 cram 166.3 MB
EGAF00004854328 cram 166.6 MB
EGAF00004854329 cram 172.2 MB
EGAF00004854330 cram 150.7 MB
EGAF00004854331 cram 149.7 MB
EGAF00004854332 cram 160.6 MB
EGAF00004854333 cram 157.3 MB
EGAF00004854334 cram 194.0 MB
EGAF00004854335 cram 144.4 MB
EGAF00004854336 cram 169.6 MB
EGAF00004854337 cram 169.7 MB
EGAF00004854338 cram 175.5 MB
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EGAF00004854340 cram 149.6 MB
EGAF00004854341 cram 157.4 MB
EGAF00004854342 cram 160.7 MB
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EGAF00004854344 cram 180.3 MB
EGAF00004854345 cram 169.1 MB
EGAF00004854346 cram 165.9 MB
EGAF00004854347 cram 144.0 MB
EGAF00004854348 cram 164.4 MB
EGAF00004854349 cram 147.8 MB
EGAF00004854350 cram 153.6 MB
EGAF00004854351 cram 148.8 MB
EGAF00004854352 cram 174.0 MB
EGAF00004854353 cram 148.9 MB
EGAF00004854354 cram 140.5 MB
EGAF00004854355 cram 142.2 MB
EGAF00004854356 cram 133.5 MB
EGAF00004854357 cram 149.1 MB
EGAF00004854358 cram 169.4 MB
EGAF00004854359 cram 149.9 MB
EGAF00004854360 cram 150.2 MB
EGAF00004854361 cram 156.0 MB
EGAF00004854362 cram 147.5 MB
EGAF00004854363 cram 141.6 MB
EGAF00004854364 cram 146.3 MB
EGAF00004854365 cram 155.8 MB
EGAF00004854366 cram 171.6 MB
EGAF00004854367 cram 158.4 MB
EGAF00004854368 cram 169.4 MB
EGAF00004854369 cram 145.0 MB
EGAF00004854370 cram 149.2 MB
EGAF00004854371 cram 146.5 MB
EGAF00004854372 cram 164.5 MB
EGAF00004854373 cram 133.3 MB
EGAF00004854374 cram 176.0 MB
EGAF00004854375 cram 144.9 MB
EGAF00004854376 cram 166.4 MB
EGAF00004854377 cram 169.3 MB
EGAF00004854378 cram 165.8 MB
EGAF00004854379 cram 148.9 MB
EGAF00004854380 cram 143.4 MB
EGAF00004854381 cram 141.7 MB
EGAF00004854382 cram 156.8 MB
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EGAF00004854385 cram 172.1 MB
EGAF00004854386 cram 150.6 MB
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EGAF00004854404 cram 164.6 MB
EGAF00004854405 cram 147.6 MB
EGAF00004854406 cram 153.3 MB
EGAF00004854407 cram 148.8 MB
EGAF00004854408 cram 174.1 MB
EGAF00004854409 cram 149.4 MB
EGAF00004854410 cram 140.8 MB
EGAF00004854411 cram 142.5 MB
EGAF00004854412 cram 134.0 MB
EGAF00004854413 cram 149.5 MB
EGAF00004854414 cram 169.8 MB
EGAF00004854415 cram 150.7 MB
EGAF00004854416 cram 150.5 MB
EGAF00004854417 cram 156.5 MB
EGAF00004854418 cram 147.8 MB
EGAF00004854419 cram 141.8 MB
EGAF00004854420 cram 146.8 MB
EGAF00004854421 cram 156.3 MB
EGAF00004854422 cram 172.1 MB
EGAF00004854423 cram 158.8 MB
EGAF00004854424 cram 169.9 MB
EGAF00004854425 cram 145.6 MB
EGAF00004854426 cram 149.9 MB
EGAF00004854427 cram 146.9 MB
EGAF00004854428 cram 165.1 MB
EGAF00004854429 cram 133.9 MB
EGAF00004854430 cram 176.9 MB
EGAF00004854431 cram 145.7 MB
EGAF00004854432 cram 166.8 MB
EGAF00004854433 cram 169.7 MB
EGAF00004854434 cram 166.4 MB
EGAF00004854435 cram 149.2 MB
EGAF00004854436 cram 143.9 MB
EGAF00004854437 cram 142.3 MB
EGAF00004854438 cram 156.6 MB
EGAF00004854439 cram 167.6 MB
EGAF00004854440 cram 167.1 MB
EGAF00004854441 cram 172.7 MB
EGAF00004854442 cram 151.1 MB
EGAF00004854443 cram 150.0 MB
EGAF00004854444 cram 160.7 MB
EGAF00004854445 cram 157.4 MB
EGAF00004854446 cram 193.9 MB
EGAF00004854447 cram 144.6 MB
EGAF00004854448 cram 169.5 MB
EGAF00004854449 cram 169.7 MB
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EGAF00004854451 cram 142.7 MB
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EGAF00004854453 cram 157.1 MB
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EGAF00004854507 cram 143.4 MB
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EGAF00004854511 cram 144.5 MB
EGAF00004854512 cram 181.2 MB
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EGAF00004854515 cram 146.2 MB
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1416 Files (288.3 GB)