Human T-bet governs innate and innate-like adaptive IFN-g immunity against mycobacteria.

We report a patient with mycobacterial disease due to inherited deficiency of the transcription factor T-bet. PBMCs from the patient and his heterozygous father were analyzed with scRNA-seq. these represent 2 single cell RNA samples generated using the 0xGenomics technology and being processed through cell ranger.

2 samples
DAC: EGAC00001001822
Technology: Illumina HiSeq 4000

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HMB DUO:0000006 (version: 2019-01-07)health or medical or biomedical researchThis data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry.

We report a patient with mycobacterial disease due to inherited deficiency of the transcription factor T-bet. PBMCs from the patient was analyzed with scRNA-seq.

Further information and request for resources and reagents should be directed to and will be fulfilled by the Lead Contact, Jean-Laurent Casanova (casanova@mail.rockefeller.edu)

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID	Study Title	Study Type
EGAS00001004504	Human T-bet governs innate and innate-like adaptive IFN-g immunity against mycobacteria.	Other

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ID	File Type	Size
EGAF00004859520	bam	71.2 GB
EGAF00004859521	bam	70.6 GB
2 Files (141.8 GB)