Inherited CD28 deficiency in otherwise healthy patients with disseminated warts and giant horns
this dataset corresponds to 3 patient of HPV-driven warts single cell RNA data generated through the 10X genomics platform and aligned on GRCh38 reference using the cell ranger tools.
- 4 samples
- DAC: EGAC00001001835
- Technologies: Illumina NovaSeq 6000, NextSeq 550
This study presents the analysis of a patient with the HPV-2-driven “tree man” phenotype, and two of his distant relatives with unusually severe HPV4-driven warts. All three patients are homozygous for a private CD28 variant. The data available here are 10X Genomics 3' scRNA-seq data of the three patients.
Further information and request for resources and reagents should be directed to and will be fulfilled by the Lead Contact, Jean-Laurent Casanova (casanova@mail.rockefeller.edu)
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001004837 | Transcriptome Analysis |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.