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Fecal whole metagenomic shotgun sequencing data.

Human fecal WMS data from patients treated with combined anti-CTLA-4 and anti-PD-1 immunotherapy for advanced melanoma.

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Data access and use for 16S/WMS data.

DATA ACCESS AGREEMENT This Data Access Agreement (“Agreement”), effective as of the ____ day of _________________, 20__ (“Effective Date”), is by and between The University of Texas M. D. Anderson Cancer Center, an institution of The University of Texas System and an agency of the State of Texas, with an address at 1515 Holcombe Boulevard, Houston, Texas 77030 (“Provider”), and _____________ (“Recipient”) on behalf of its investigator _____________ (“Recipient Investigator”) (collectively, the “Parties”; each, a “Party”). RECITALS Provider maintains the following de-identified data in the European Genome-phenome Archive (EGA) managed by the European Bioinformatics Institute (“Data”); Accession EGAS00001004885: Gut microbiome sequencing in patients receiving combination immune checkpoint blockade. This dataset contains paired-end sequencing fastq files for 54 human fecal 16S rRNA gene sequencing samples and 46 human fecal whole metagenome shotgun sequencing samples and associated phenotype metadata. All samples were obtained from patients with advanced melanoma who were treated with combined anti-CTLA-4 and anti-PD-1 checkpoint blockade immunotherapy. and Provider is willing to allow Recipient to access such Data from the EGA for the internal non-commercial research purposes of (“Purpose”); Use of the data is reserved for Non-Profit Institutions only and all findings must be made available to the public and available to the larger scientific community. Allowable Research Projects must be for cancer-related research. pursuant to the terms of this Agreement. In consideration of the mutual promises and covenants herein, and for other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the Parties agree as follows: 1. The Data will be used solely for the Research by Recipient Investigator and personnel under his immediate supervision at Recipient and may not be transferred to any other investigator or to any third party without prior written permission from Provider. The Material may not be used for any purpose other than the Research, including without limitation for any commercial purpose or for research in human subjects (including, without limitation, in diagnostic testing). 2. Neither Recipient nor Recipient Investigator shall disclose Data to any person or party other than the Recipient Investigator hereunder without Provider’s prior written consent. 3. The Data will be used in compliance with all applicable laws, regulations, and guidelines applicable to the Data, including without limitation any applicable export controls. 4. In any publication resulting from use of the Data, Recipient and Recipient Investigator shall acknowledge ______________ (“Provider Investigator”) and Provider as the provider of the Data. 5. This Agreement shall be effective as of the Effective Date and shall remain effective until completion of the Research. Either Party may terminate this Agreement with or without cause upon thirty (30) days’ written notice to the other Party. Upon expiration or termination of this Agreement for any reason, Recipient shall destroy all Data received pursuant to this Agreement. 6. Any notice permitted or required as provided for herein shall be in writing and to the contact and address as noted below or as may be provided by either party to the other in writing from time to time.   Notice to Provider shall be to: Chief Legal Officer The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Blvd., Unit 1674 Houston, Texas 77030 Phone: 713-745-6633; Facsimile: 713-745-6029 With a copy to: The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Blvd., Unit 1676 Office of Research Administration Attn: AVP, Research Administration Houston, TX 77030 Phone: 713-792-3672; Facsimile: 713-792-7455 Notice to Recipient shall be to: __________________________ __________________________ __________________________ __________________________ __________________________ 7. In the event Protected Health Information (“PHI”), as defined by the federal Health Insurance Portability and Accountability Act of 1996 (“HIPAA”), as amended, is inadvertently created, accessed by, and/or disclosed to Recipient in connection with this Agreement, Recipient will immediately notify the Provider and will return to Provider or destroy such PHI, in accordance with the Provider’s instructions. Pending return or destruction of any PHI, Recipient shall maintain the confidentiality of all Data (including the PHI) and use appropriate safeguards to prevent access to, use, or disclosure of Data (including the PHI). 8. PROVIDER MAKES NO REPRESENTATION OR WARRANTY CONCERNING THE MATERIAL, INCLUDING WITHOUT LIMITATION, WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OR ANY OTHER WARRANTY, EXPRESS OR IMPLIED. 9. Recipient Investigator and Recipient accept all liability for any use of the Data and for any loss, claim, or damage which may arise from or in connection with this Agreement or the use, handling or storage of the Data and in no event shall Provider or Provider Investigator be liable for any such use, loss, claim or damage. 10. This Agreement is via EGA mechanism.   [Insert Recipient Name Here] THE UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER By: By: Name: Name: Title: Title: Date: Date: Read and Understood: Read and Understood: Recipient Scientist: Provider Scientist: Name: Name: Title: Title: Date: Date:

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004885 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00004939259 fastq.bz2 2.5 GB
EGAF00004939260 fastq.bz2 2.6 GB
EGAF00004939269 fastq.bz2 3.7 GB
EGAF00004939270 fastq.bz2 3.8 GB
EGAF00004939271 fastq.bz2 2.2 GB
EGAF00004939272 fastq.bz2 2.3 GB
EGAF00004939275 fastq.bz2 2.3 GB
EGAF00004939276 fastq.bz2 2.2 GB
EGAF00004939279 fastq.bz2 2.2 GB
EGAF00004939280 fastq.bz2 2.1 GB
EGAF00004939281 fastq.bz2 1.8 GB
EGAF00004939282 fastq.bz2 1.9 GB
EGAF00004939283 fastq.bz2 3.6 GB
EGAF00004939284 fastq.bz2 3.6 GB
EGAF00004939285 fastq.bz2 4.0 GB
EGAF00004939286 fastq.bz2 4.1 GB
EGAF00004939287 fastq.bz2 2.6 GB
EGAF00004939288 fastq.bz2 2.6 GB
EGAF00004939289 fastq.bz2 3.1 GB
EGAF00004939290 fastq.bz2 3.2 GB
EGAF00004939291 fastq.bz2 3.6 GB
EGAF00004939292 fastq.bz2 3.6 GB
EGAF00004939293 fastq.bz2 2.2 GB
EGAF00004939294 fastq.bz2 2.3 GB
EGAF00004939299 fastq.bz2 2.4 GB
EGAF00004939300 fastq.bz2 2.6 GB
EGAF00004939311 fastq.bz2 2.3 GB
EGAF00004939312 fastq.bz2 2.4 GB
EGAF00004939313 fastq.bz2 2.1 GB
EGAF00004939314 fastq.bz2 2.1 GB
EGAF00004939315 fastq.bz2 2.9 GB
EGAF00004939316 fastq.bz2 3.0 GB
EGAF00004939317 fastq.bz2 2.0 GB
EGAF00004939318 fastq.bz2 2.1 GB
EGAF00004939319 fastq.bz2 2.9 GB
EGAF00004939320 fastq.bz2 2.9 GB
EGAF00004939321 fastq.bz2 2.9 GB
EGAF00004939322 fastq.bz2 3.0 GB
EGAF00004939323 fastq.bz2 2.9 GB
EGAF00004939324 fastq.bz2 2.8 GB
EGAF00004939325 fastq.bz2 742.9 MB
EGAF00004939326 fastq.bz2 780.6 MB
EGAF00004939331 fastq.bz2 1.4 GB
EGAF00004939332 fastq.bz2 1.5 GB
EGAF00004939337 fastq.bz2 1.6 GB
EGAF00004939338 fastq.bz2 1.5 GB
EGAF00004939339 fastq.bz2 2.0 GB
EGAF00004939340 fastq.bz2 2.0 GB
EGAF00004939341 fastq.bz2 1.5 GB
EGAF00004939342 fastq.bz2 1.6 GB
EGAF00004939343 fastq.bz2 1.3 GB
EGAF00004939344 fastq.bz2 1.3 GB
EGAF00004939345 fastq.bz2 1.4 GB
EGAF00004939346 fastq.bz2 1.5 GB
EGAF00004939347 fastq.bz2 1.1 GB
EGAF00004939348 fastq.bz2 1.1 GB
EGAF00004939349 fastq.bz2 3.4 GB
EGAF00004939350 fastq.bz2 3.6 GB
EGAF00004939363 fastq.bz2 3.4 GB
EGAF00004939364 fastq.bz2 3.2 GB
EGAF00004939365 fastq.bz2 3.5 GB
EGAF00004939366 fastq.bz2 3.6 GB
EGAF00004939367 fastq.bz2 3.4 GB
EGAF00004939368 fastq.bz2 3.5 GB
EGAF00004939369 fastq.bz2 2.1 GB
EGAF00004939370 fastq.bz2 2.2 GB
EGAF00004939371 fastq.bz2 2.6 GB
EGAF00004939372 fastq.bz2 2.7 GB
EGAF00004939373 fastq.bz2 2.0 GB
EGAF00004939374 fastq.bz2 2.0 GB
EGAF00004939375 fastq.bz2 2.3 GB
EGAF00004939376 fastq.bz2 2.3 GB
EGAF00004939377 fastq.bz2 2.3 GB
EGAF00004939378 fastq.bz2 2.4 GB
EGAF00004939389 fastq.bz2 3.3 GB
EGAF00004939390 fastq.bz2 3.3 GB
EGAF00004939427 fastq.bz2 1.7 GB
EGAF00004939428 fastq.bz2 1.8 GB
EGAF00004939429 fastq.bz2 1.9 GB
EGAF00004939430 fastq.bz2 2.0 GB
EGAF00004939431 fastq.bz2 1.9 GB
EGAF00004939432 fastq.bz2 2.0 GB
EGAF00004939433 fastq.bz2 2.6 GB
EGAF00004939434 fastq.bz2 2.6 GB
EGAF00004939435 fastq.bz2 3.0 GB
EGAF00004939436 fastq.bz2 3.1 GB
EGAF00004939439 fastq.bz2 3.1 GB
EGAF00004939440 fastq.bz2 3.2 GB
EGAF00004939441 fastq.bz2 1.7 GB
EGAF00004939442 fastq.bz2 1.8 GB
EGAF00004939443 fastq.bz2 3.3 GB
EGAF00004939444 fastq.bz2 3.3 GB
92 Files (228.5 GB)