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MutWP5: CRUK Mutographs of Cancer: Lung: PD37920 (Targeted) (2021-02-02)

Sequencing of LCM-derived microbiopsies from explanted lung from COPD patient. Goal to assess the mutational burden, spectrum, and clonal dynamics within the tissue. Deep sampling throughout multiple regions of the lung will determine whether there are differences in smoking-related mutation burden in different portions of the lung. Targeted sequencing will be conducted on samples to identify drivers of interest and clonality of the samples, well-performing samples will be sent for subsequent whole-genome sequencing. Results from this portion of the study will be compared to other individuals with smoking-related diseases (COPD, pulmonary fibrosis, lung cancer), and normal, non-smoking lungs. . This dataset contains all the data available for this study on 2021-02-02.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001003321 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002554561 cram 362.1 MB
EGAF00002554562 cram 397.8 MB
EGAF00002554563 cram 352.6 MB
EGAF00002554564 cram 416.0 MB
EGAF00002554565 cram 369.3 MB
EGAF00002554566 cram 360.8 MB
EGAF00002554567 cram 384.6 MB
EGAF00002554568 cram 367.2 MB
EGAF00002554569 cram 427.1 MB
EGAF00002554570 cram 533.6 MB
EGAF00002554571 cram 398.9 MB
EGAF00002554572 cram 373.9 MB
EGAF00002554573 cram 402.7 MB
EGAF00002554574 cram 464.2 MB
EGAF00002554575 cram 378.0 MB
EGAF00002554576 cram 393.5 MB
EGAF00002554577 cram 456.5 MB
EGAF00002554578 cram 367.3 MB
EGAF00002554579 cram 408.5 MB
EGAF00002554580 cram 433.4 MB
EGAF00002554581 cram 396.6 MB
EGAF00002554582 cram 427.7 MB
EGAF00002554583 cram 409.3 MB
EGAF00002554584 cram 426.7 MB
EGAF00002883976 cram 6.2 GB
EGAF00002883977 cram 5.8 GB
EGAF00002883978 cram 6.0 GB
EGAF00002883979 cram 6.3 GB
EGAF00002883980 cram 5.8 GB
EGAF00002883981 cram 6.2 GB
30 Files (46.0 GB)