Need Help?

CD19 CAR-T cells from non-Hodgkin's lymphoma patients

The samples across 17 NHL patient samples with the CD19 CAR-T treatments are sequenced in 10x genomics. Refer to the manuscript supplementary tables and "https://github.com/hwanglab/hwanglab_2021_tigitCarT" for the sequencing sample sheets, the patient clinical information, processed data, and source codes.

Request Access

Sequential single-cell transcriptional and protein marker profiling reveals TIGIT as a marker of CD19 CAR-T cell dysfunction in patients with non-Hodgkin’s lymphoma

1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify XXXXX within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify XXXXX prior to any significant changes to the protocol for the Project. 14. The User Institution will notify XXXXX as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. XXXXX may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than XXXXX. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001005356 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005309461 fastq.gz 2.4 GB
EGAF00005309462 fastq.gz 5.5 GB
EGAF00005309463 fastq.gz 88.3 MB
EGAF00005309464 fastq.gz 166.9 MB
EGAF00005309465 fastq.gz 2.7 GB
EGAF00005309466 fastq.gz 6.1 GB
EGAF00005309467 fastq.gz 1.3 GB
EGAF00005309468 fastq.gz 2.9 GB
EGAF00005309469 fastq.gz 18.5 GB
EGAF00005309470 fastq.gz 17.8 GB
EGAF00005309471 fastq.gz 17.8 GB
EGAF00005309472 fastq.gz 17.2 GB
EGAF00005309473 fastq.gz 14.1 GB
EGAF00005309474 fastq.gz 12.0 GB
EGAF00005309475 fastq.gz 17.6 GB
EGAF00005309476 fastq.gz 14.9 GB
EGAF00005309477 fastq.gz 17.8 GB
EGAF00005309478 fastq.gz 17.4 GB
EGAF00005309479 fastq.gz 289.3 MB
EGAF00005309480 fastq.gz 443.4 MB
EGAF00005309481 fastq.gz 18.6 GB
EGAF00005309482 fastq.gz 18.1 GB
EGAF00005309483 fastq.gz 186.9 MB
EGAF00005309484 fastq.gz 341.3 MB
EGAF00005309485 fastq.gz 95.0 MB
EGAF00005309486 fastq.gz 178.6 MB
EGAF00005309487 fastq.gz 504.9 MB
EGAF00005309488 fastq.gz 865.9 MB
EGAF00005309489 fastq.gz 15.6 GB
EGAF00005309490 fastq.gz 15.6 GB
EGAF00005309491 fastq.gz 18.1 GB
EGAF00005309492 fastq.gz 17.5 GB
EGAF00005309493 fastq.gz 68.3 MB
EGAF00005309494 fastq.gz 123.0 MB
EGAF00005309495 fastq.gz 417.5 MB
EGAF00005309496 fastq.gz 949.2 MB
EGAF00005309497 fastq.gz 2.3 GB
EGAF00005309498 fastq.gz 5.4 GB
EGAF00005309499 fastq.gz 2.0 GB
EGAF00005309500 fastq.gz 4.5 GB
EGAF00005309501 fastq.gz 24.7 GB
EGAF00005309502 fastq.gz 23.9 GB
EGAF00005309503 fastq.gz 17.9 GB
EGAF00005309504 fastq.gz 17.3 GB
EGAF00005309505 fastq.gz 89.6 MB
EGAF00005309506 fastq.gz 159.5 MB
EGAF00005309507 fastq.gz 1.7 GB
EGAF00005309508 fastq.gz 4.0 GB
EGAF00005309509 fastq.gz 1.7 GB
EGAF00005309510 fastq.gz 4.0 GB
EGAF00005309511 fastq.gz 1.5 GB
EGAF00005309512 fastq.gz 3.5 GB
EGAF00005309513 fastq.gz 54.6 MB
EGAF00005309514 fastq.gz 98.2 MB
EGAF00005309515 fastq.gz 122.6 MB
EGAF00005309516 fastq.gz 223.0 MB
EGAF00005309517 fastq.gz 95.1 MB
EGAF00005309518 fastq.gz 176.5 MB
EGAF00005309519 fastq.gz 35.4 MB
EGAF00005309520 fastq.gz 38.6 MB
EGAF00005309521 fastq.gz 18.4 GB
EGAF00005309522 fastq.gz 17.9 GB
EGAF00005309523 fastq.gz 22.3 GB
EGAF00005309524 fastq.gz 21.3 GB
EGAF00005309525 fastq.gz 23.9 GB
EGAF00005309526 fastq.gz 22.9 GB
EGAF00005309527 fastq.gz 17.3 GB
EGAF00005309528 fastq.gz 16.9 GB
EGAF00005309529 fastq.gz 21.0 GB
EGAF00005309530 fastq.gz 20.5 GB
EGAF00005309531 fastq.gz 150.3 MB
EGAF00005309532 fastq.gz 277.9 MB
EGAF00005309533 fastq.gz 164.1 MB
EGAF00005309534 fastq.gz 307.8 MB
EGAF00005309535 fastq.gz 185.4 MB
EGAF00005309536 fastq.gz 339.6 MB
EGAF00005309537 fastq.gz 133.8 MB
EGAF00005309538 fastq.gz 249.3 MB
EGAF00005309539 fastq.gz 17.4 GB
EGAF00005309540 fastq.gz 17.2 GB
EGAF00005309541 fastq.gz 191.1 MB
EGAF00005309542 fastq.gz 423.9 MB
EGAF00005309543 fastq.gz 1.3 GB
EGAF00005309544 fastq.gz 3.0 GB
EGAF00005309545 fastq.gz 20.3 GB
EGAF00005309546 fastq.gz 19.9 GB
EGAF00005309547 fastq.gz 17.3 GB
EGAF00005309548 fastq.gz 16.9 GB
EGAF00005309549 fastq.gz 18.4 GB
EGAF00005309550 fastq.gz 17.8 GB
EGAF00005309551 fastq.gz 24.0 GB
EGAF00005309552 fastq.gz 22.8 GB
EGAF00005309553 fastq.gz 191.8 MB
EGAF00005309554 fastq.gz 432.0 MB
EGAF00005309555 fastq.gz 1.6 GB
EGAF00005309556 fastq.gz 3.6 GB
EGAF00005309557 fastq.gz 21.9 GB
EGAF00005309558 fastq.gz 20.9 GB
EGAF00005309559 fastq.gz 64.3 MB
EGAF00005309560 fastq.gz 115.9 MB
EGAF00005309561 fastq.gz 103.1 MB
EGAF00005309562 fastq.gz 186.1 MB
EGAF00005309563 fastq.gz 208.4 MB
EGAF00005309564 fastq.gz 382.7 MB
EGAF00005309565 fastq.gz 61.6 MB
EGAF00005309566 fastq.gz 113.5 MB
EGAF00005309567 fastq.gz 1.8 GB
EGAF00005309568 fastq.gz 3.5 GB
EGAF00005309569 fastq.gz 2.6 GB
EGAF00005309570 fastq.gz 6.0 GB
EGAF00005309571 fastq.gz 2.6 GB
EGAF00005309572 fastq.gz 5.9 GB
EGAF00005309573 fastq.gz 11.7 GB
EGAF00005309574 fastq.gz 21.6 GB
EGAF00005309575 fastq.gz 2.6 GB
EGAF00005309576 fastq.gz 6.0 GB
EGAF00005309577 fastq.gz 25.2 GB
EGAF00005309578 fastq.gz 22.3 GB
EGAF00005309579 fastq.gz 22.3 GB
EGAF00005309580 fastq.gz 19.7 GB
EGAF00005309581 fastq.gz 9.9 GB
EGAF00005309582 fastq.gz 8.6 GB
EGAF00005309583 fastq.gz 16.4 GB
EGAF00005309584 fastq.gz 15.1 GB
EGAF00005309585 fastq.gz 16.3 GB
EGAF00005309586 fastq.gz 15.9 GB
EGAF00005309587 fastq.gz 19.0 GB
EGAF00005309588 fastq.gz 17.6 GB
EGAF00005309589 fastq.gz 210.5 MB
EGAF00005309590 fastq.gz 390.2 MB
EGAF00005309591 fastq.gz 17.5 GB
EGAF00005309592 fastq.gz 17.4 GB
EGAF00005309593 fastq.gz 54.6 MB
EGAF00005309594 fastq.gz 100.9 MB
EGAF00005309595 fastq.gz 89.7 MB
EGAF00005309596 fastq.gz 162.5 MB
EGAF00005309597 fastq.gz 17.5 GB
EGAF00005309598 fastq.gz 17.5 GB
EGAF00005309599 fastq.gz 16.2 GB
EGAF00005309600 fastq.gz 15.5 GB
EGAF00005309601 fastq.gz 17.3 GB
EGAF00005309602 fastq.gz 16.8 GB
EGAF00005309603 fastq.gz 230.1 MB
EGAF00005309604 fastq.gz 422.1 MB
EGAF00005309605 fastq.gz 119.7 MB
EGAF00005309606 fastq.gz 224.6 MB
EGAF00005309607 fastq.gz 19.1 GB
EGAF00005309608 fastq.gz 16.0 GB
EGAF00005309609 fastq.gz 14.5 GB
EGAF00005309610 fastq.gz 12.3 GB
EGAF00005309611 fastq.gz 17.0 GB
EGAF00005309612 fastq.gz 16.7 GB
EGAF00005309613 fastq.gz 20.3 GB
EGAF00005309614 fastq.gz 19.5 GB
EGAF00005309615 fastq.gz 22.3 GB
EGAF00005309616 fastq.gz 21.9 GB
EGAF00005309617 fastq.gz 10.9 GB
EGAF00005309618 fastq.gz 10.5 GB
EGAF00005309619 fastq.gz 895.0 MB
EGAF00005309620 fastq.gz 1.9 GB
EGAF00005309621 fastq.gz 25.4 GB
EGAF00005309622 fastq.gz 22.4 GB
EGAF00005309623 fastq.gz 22.3 GB
EGAF00005309624 fastq.gz 20.9 GB
EGAF00005309625 fastq.gz 21.1 GB
EGAF00005309626 fastq.gz 19.8 GB
EGAF00005309627 fastq.gz 17.3 GB
EGAF00005309628 fastq.gz 16.3 GB
EGAF00005309629 fastq.gz 2.4 GB
EGAF00005309630 fastq.gz 5.6 GB
EGAF00005309631 fastq.gz 2.2 GB
EGAF00005309632 fastq.gz 5.1 GB
EGAF00005309633 fastq.gz 2.5 GB
EGAF00005309634 fastq.gz 5.8 GB
EGAF00005309635 fastq.gz 15.2 GB
EGAF00005309636 fastq.gz 37.7 GB
EGAF00005309637 fastq.gz 16.0 GB
EGAF00005309638 fastq.gz 15.8 GB
EGAF00005309639 fastq.gz 2.8 GB
EGAF00005309640 fastq.gz 5.4 GB
EGAF00005309641 fastq.gz 17.4 GB
EGAF00005309642 fastq.gz 17.0 GB
EGAF00005309643 fastq.gz 2.2 GB
EGAF00005309644 fastq.gz 5.0 GB
EGAF00005309645 fastq.gz 1.6 GB
EGAF00005309646 fastq.gz 3.9 GB
EGAF00005309647 fastq.gz 8.5 GB
EGAF00005309648 fastq.gz 6.3 GB
EGAF00005309649 fastq.gz 21.1 GB
EGAF00005309650 fastq.gz 19.5 GB
EGAF00005309651 fastq.gz 188.0 MB
EGAF00005309652 fastq.gz 354.5 MB
EGAF00005309653 fastq.gz 20.2 GB
EGAF00005309654 fastq.gz 18.8 GB
EGAF00005309655 fastq.gz 16.3 GB
EGAF00005309656 fastq.gz 15.3 GB
EGAF00005309657 fastq.gz 175.8 MB
EGAF00005309658 fastq.gz 317.4 MB
EGAF00005309659 fastq.gz 166.7 MB
EGAF00005309660 fastq.gz 315.2 MB
EGAF00005309661 fastq.gz 19.1 GB
EGAF00005309662 fastq.gz 18.7 GB
EGAF00005309663 fastq.gz 982.4 MB
EGAF00005309664 fastq.gz 2.1 GB
EGAF00005309665 fastq.gz 39.4 MB
EGAF00005309666 fastq.gz 86.3 MB
EGAF00005309667 fastq.gz 22.0 GB
EGAF00005309668 fastq.gz 21.6 GB
EGAF00005309669 fastq.gz 2.3 GB
EGAF00005309670 fastq.gz 5.4 GB
EGAF00005309671 fastq.gz 2.2 GB
EGAF00005309672 fastq.gz 5.2 GB
EGAF00005309673 fastq.gz 1.7 GB
EGAF00005309674 fastq.gz 4.0 GB
EGAF00005309675 fastq.gz 72.8 MB
EGAF00005309676 fastq.gz 137.1 MB
EGAF00005309677 fastq.gz 151.0 MB
EGAF00005309678 fastq.gz 283.7 MB
218 Files (2.0 TB)