Nuclease deficiencies alter plasma cell-free DNA methylation profiles (Mouse samples)

Dataset ID Technology Samples
EGAD00001007751 Illumina HiSeq 4000,NextSeq 500 36

Dataset Description

The dataset contains sequencing data in wildtype, Dnase1-deficient and Dnase1l3-deficient mice. We performed 2 x 75bp paired-end whole genome bisulfite sequencing of pooled plasma cell-free DNA (cfDNA) and buffy coat genomic DNA. The effects of DNASE1L3 or DNASE1 deficiency on cfDNA methylation was explored in plasma of mice deficient in these nucleases.

Who controls access to this dataset

For each dataset that requires controlled access, there is a corresponding Data Access Committee (DAC) who determine access permissions. Access to actual data files is not managed by the EGA. If you need to request access to this data set, please contact:

The Chinese University of Hong Kong (CUHK) Circulating Nucleic Acids Research Group (CNARG)
Contact person: Peiyong Jiang
Email: jiangpeiyong [at] cuhk [dot] edu [dot] hk
More details: EGAC00001000078


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