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Adult-type Granulosa Cell Tumour of the Ovary RNA Sequencing

We analyzed 34 AGCTs (19 primary and 15 recurrent) and the KGN cell line by RNA-Seq. Our cohort comprised of 3 AGCTs WT for FOXL2, 28 heterozygous and 3 homo/hemizygous for the pathogenic variant. Fresh-frozen AGCTs were selected from OVCARE’s Gynecological Tissue Bank in Vancouver, Canada for bulk RNA-seq. RNA was extracted from frozen tissue and sections adjacent to the scrolls submitted for RNA-seq were stained with hematoxylin and eosin (H&E) to evaluate tumour cell purity. Cases with >80% tumour cell purity were selected for sequencing with the majority of cases (29 of 34 patients) containing >90% tumour cells. Ribodepleted RNA libraries were constructed and paired-end sequencing (125 base pair reads) was performed.

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DUO:0000007
version: 2019-01-07

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO:0023283

DUO:0000012
version: 2021-02-23

research specific restrictions

This data use modifier indicates that use is limited to studies of a certain research type.

DUO:0000019
version: 2019-01-07

publication required

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DUO:0000021
version: 2019-01-07

ethics approval required

This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.

DUO:0000025
version: 2021-02-23

time limit on use

This data use modifier indicates that use is approved for a specific number of months.

DUO:0000026
version: 2019-01-07

user specific restriction

This data use modifier indicates that use is limited to use by approved users.

DUO:0000027
version: 2019-01-07

project specific restriction

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DUO:0000028
version: 2019-01-07

institution specific restriction

This data use modifier indicates that use is limited to use within an approved institution.

DUO:0000046
version: 2021-02-23

non-commercial use only

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BC Cancer, part of the Provincial Health Services Authority - Data Access Policy

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001005414 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00005331931 fastq.gz 4.3 GB Report
EGAF00005331932 fastq.gz 4.4 GB Report
EGAF00005331933 fastq.gz 4.8 GB Report
EGAF00005331934 fastq.gz 4.9 GB Report
EGAF00005331935 fastq.gz 6.3 GB Report
EGAF00005331936 fastq.gz 6.5 GB Report
EGAF00005331937 fastq.gz 6.3 GB Report
EGAF00005331938 fastq.gz 6.5 GB Report
EGAF00005331939 fastq.gz 6.4 GB Report
EGAF00005331940 fastq.gz 6.6 GB Report
EGAF00005331941 fastq.gz 5.0 GB Report
EGAF00005331942 fastq.gz 5.0 GB Report
EGAF00005331943 fastq.gz 5.4 GB Report
EGAF00005331944 fastq.gz 5.5 GB Report
EGAF00005331945 fastq.gz 4.4 GB Report
EGAF00005331946 fastq.gz 4.6 GB Report
EGAF00005331947 fastq.gz 4.0 GB Report
EGAF00005331948 fastq.gz 4.1 GB Report
EGAF00005331949 fastq.gz 5.8 GB Report
EGAF00005331950 fastq.gz 6.0 GB Report
EGAF00005331951 fastq.gz 5.1 GB Report
EGAF00005331952 fastq.gz 5.1 GB Report
EGAF00005331953 fastq.gz 6.1 GB Report
EGAF00005331954 fastq.gz 6.3 GB Report
EGAF00005331955 fastq.gz 5.3 GB Report
EGAF00005331956 fastq.gz 5.3 GB Report
EGAF00005331957 fastq.gz 5.0 GB Report
EGAF00005331958 fastq.gz 5.1 GB Report
EGAF00005331959 fastq.gz 4.3 GB Report
EGAF00005331960 fastq.gz 4.4 GB Report
EGAF00005331961 fastq.gz 4.7 GB Report
EGAF00005331962 fastq.gz 4.8 GB Report
EGAF00005331963 fastq.gz 5.1 GB Report
EGAF00005331964 fastq.gz 5.2 GB Report
EGAF00005331965 fastq.gz 4.8 GB Report
EGAF00005331966 fastq.gz 4.9 GB Report
EGAF00005331967 fastq.gz 4.7 GB Report
EGAF00005331968 fastq.gz 4.8 GB Report
EGAF00005331969 fastq.gz 5.3 GB Report
EGAF00005331970 fastq.gz 5.5 GB Report
EGAF00005331971 fastq.gz 5.0 GB Report
EGAF00005331972 fastq.gz 5.0 GB Report
EGAF00005331973 fastq.gz 5.0 GB Report
EGAF00005331974 fastq.gz 5.1 GB Report
EGAF00005331975 fastq.gz 5.3 GB Report
EGAF00005331976 fastq.gz 5.5 GB Report
EGAF00005331977 fastq.gz 5.7 GB Report
EGAF00005331978 fastq.gz 5.7 GB Report
EGAF00005331979 fastq.gz 5.4 GB Report
EGAF00005331980 fastq.gz 5.4 GB Report
EGAF00005331981 fastq.gz 6.2 GB Report
EGAF00005331982 fastq.gz 6.3 GB Report
EGAF00005331983 fastq.gz 5.4 GB Report
EGAF00005331984 fastq.gz 5.6 GB Report
EGAF00005331985 fastq.gz 6.4 GB Report
EGAF00005331986 fastq.gz 6.6 GB Report
EGAF00005331987 fastq.gz 6.1 GB Report
EGAF00005331988 fastq.gz 6.2 GB Report
EGAF00005331989 fastq.gz 4.3 GB Report
EGAF00005331990 fastq.gz 4.4 GB Report
EGAF00005331991 fastq.gz 5.3 GB Report
EGAF00005331992 fastq.gz 5.5 GB Report
EGAF00005331993 fastq.gz 4.9 GB Report
EGAF00005331994 fastq.gz 5.1 GB Report
EGAF00005331995 fastq.gz 5.5 GB Report
EGAF00005331996 fastq.gz 5.7 GB Report
EGAF00005331997 fastq.gz 4.8 GB Report
EGAF00005331998 fastq.gz 5.0 GB Report
EGAF00005331999 fastq.gz 4.7 GB Report
EGAF00005332000 fastq.gz 4.8 GB Report
70 Files (370.9 GB)