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Adult-type Granulosa Cell Tumour of the Ovary RNA Sequencing

We analyzed 34 AGCTs (19 primary and 15 recurrent) and the KGN cell line by RNA-Seq. Our cohort comprised of 3 AGCTs WT for FOXL2, 28 heterozygous and 3 homo/hemizygous for the pathogenic variant. Fresh-frozen AGCTs were selected from OVCARE’s Gynecological Tissue Bank in Vancouver, Canada for bulk RNA-seq. RNA was extracted from frozen tissue and sections adjacent to the scrolls submitted for RNA-seq were stained with hematoxylin and eosin (H&E) to evaluate tumour cell purity. Cases with >80% tumour cell purity were selected for sequencing with the majority of cases (29 of 34 patients) containing >90% tumour cells. Ribodepleted RNA libraries were constructed and paired-end sequencing (125 base pair reads) was performed.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001005414 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005331931 fastq.gz 4.3 GB
EGAF00005331932 fastq.gz 4.4 GB
EGAF00005331933 fastq.gz 4.8 GB
EGAF00005331934 fastq.gz 4.9 GB
EGAF00005331935 fastq.gz 6.3 GB
EGAF00005331936 fastq.gz 6.5 GB
EGAF00005331937 fastq.gz 6.3 GB
EGAF00005331938 fastq.gz 6.5 GB
EGAF00005331939 fastq.gz 6.4 GB
EGAF00005331940 fastq.gz 6.6 GB
EGAF00005331941 fastq.gz 5.0 GB
EGAF00005331942 fastq.gz 5.0 GB
EGAF00005331943 fastq.gz 5.4 GB
EGAF00005331944 fastq.gz 5.5 GB
EGAF00005331945 fastq.gz 4.4 GB
EGAF00005331946 fastq.gz 4.6 GB
EGAF00005331947 fastq.gz 4.0 GB
EGAF00005331948 fastq.gz 4.1 GB
EGAF00005331949 fastq.gz 5.8 GB
EGAF00005331950 fastq.gz 6.0 GB
EGAF00005331951 fastq.gz 5.1 GB
EGAF00005331952 fastq.gz 5.1 GB
EGAF00005331953 fastq.gz 6.1 GB
EGAF00005331954 fastq.gz 6.3 GB
EGAF00005331955 fastq.gz 5.3 GB
EGAF00005331956 fastq.gz 5.3 GB
EGAF00005331957 fastq.gz 5.0 GB
EGAF00005331958 fastq.gz 5.1 GB
EGAF00005331959 fastq.gz 4.3 GB
EGAF00005331960 fastq.gz 4.4 GB
EGAF00005331961 fastq.gz 4.7 GB
EGAF00005331962 fastq.gz 4.8 GB
EGAF00005331963 fastq.gz 5.1 GB
EGAF00005331964 fastq.gz 5.2 GB
EGAF00005331965 fastq.gz 4.8 GB
EGAF00005331966 fastq.gz 4.9 GB
EGAF00005331967 fastq.gz 4.7 GB
EGAF00005331968 fastq.gz 4.8 GB
EGAF00005331969 fastq.gz 5.3 GB
EGAF00005331970 fastq.gz 5.5 GB
EGAF00005331971 fastq.gz 5.0 GB
EGAF00005331972 fastq.gz 5.0 GB
EGAF00005331973 fastq.gz 5.0 GB
EGAF00005331974 fastq.gz 5.1 GB
EGAF00005331975 fastq.gz 5.3 GB
EGAF00005331976 fastq.gz 5.5 GB
EGAF00005331977 fastq.gz 5.7 GB
EGAF00005331978 fastq.gz 5.7 GB
EGAF00005331979 fastq.gz 5.4 GB
EGAF00005331980 fastq.gz 5.4 GB
EGAF00005331981 fastq.gz 6.2 GB
EGAF00005331982 fastq.gz 6.3 GB
EGAF00005331983 fastq.gz 5.4 GB
EGAF00005331984 fastq.gz 5.6 GB
EGAF00005331985 fastq.gz 6.4 GB
EGAF00005331986 fastq.gz 6.6 GB
EGAF00005331987 fastq.gz 6.1 GB
EGAF00005331988 fastq.gz 6.2 GB
EGAF00005331989 fastq.gz 4.3 GB
EGAF00005331990 fastq.gz 4.4 GB
EGAF00005331991 fastq.gz 5.3 GB
EGAF00005331992 fastq.gz 5.5 GB
EGAF00005331993 fastq.gz 4.9 GB
EGAF00005331994 fastq.gz 5.1 GB
EGAF00005331995 fastq.gz 5.5 GB
EGAF00005331996 fastq.gz 5.7 GB
EGAF00005331997 fastq.gz 4.8 GB
EGAF00005331998 fastq.gz 5.0 GB
EGAF00005331999 fastq.gz 4.7 GB
EGAF00005332000 fastq.gz 4.8 GB
70 Files (370.9 GB)