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Burden of DNMs in children born conceived using ART

The dataset is composed by processed whole genome sequencing data generated from 53 children and their respective parents, forming 49 trios (mother, father and child) and 2 quartets (mother, father and two siblings). A total of 18 children were born after spontaneous conception (n = 18); 17 children were born after in vitro fertilization (IVF) and another 18 children were born after intracytoplasmic sperm injection combined with testicular sperm extraction (ICSI-TESE)

Request Access

The Newcastle University Male Infertility Genomics DAC requests that any person or group wishing to gain access to the genomic data related to this study must first sign the Data Access Policy before being allowed access the genomic data of these patients/parents.

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom the Newcastle University Male Infertility Genomics DAC grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: The Newcastle University Male Infertility Genomics DAC and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. Newcastle University Male Infertility Genomics DAC: Data access committee for the Male Infertility Genomics research group lead by Professor Joris Veltman at Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, United Kingdom. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines ( ) and the Toronto Statement ( This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) ( ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) ( ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify the Newcastle University Male Infertility Genomics DAC within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify the Newcastle University Male Infertility Genomics DAC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the Newcastle University Male Infertility Genomics DAC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. The Newcastle University Male Infertility Genomics DAC may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than the Newcastle University Male Infertility Genomics DAC. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of England and Wales and shall be subject to the exclusive jurisdiction of the English courts. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for the Newcastle University Male Infertility Genomics DAC Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY APPENDIX I – DATASET DETAILS Dataset reference (EGA Study ID and Dataset Details) EGA Study ID: EGAS00001005569 Dataset details: The dataset is composed by processed genome sequencing data generated from 53 children and their respective parents, forming 49 trios (mother, father and child) and 2 quartets (mother, father and two siblings). A total of 18 children were born after spontaneous conception (n = 18); 17 children were born after in vitro fertilization (IVF) and another 18 children were born after intracytoplasmic sperm injection combined with testicular sperm extraction (ICSI-TESE). Individuals included in this study were recruited from a couples attending the fertility clinics at the RadboundUMC, the Netherlands. Name of project that created the dataset Effect of paternal ageing on de novo mutations in ART children Names of other data owners Didi D. M. Braat – Department of Obstetrics and Gynaecology, Radboudumc, Nijmegen, the Netherlands Liliana Ramos – Department of Obstetrics and Gynaecology, Radboudumc, Nijmegen, the Netherlands Specific limitations on areas of research The dataset should only be used for purposes of genetic studies in the field of infertility and is not adequate for other areas of research unless an adequate rational is provided. Minimum protection measures required The identity and anonymity of the subjects must be ensured at all times and findings relating to the health and wellbeing of these individuals should not be divulged without obtaining previous consent from the affected individuals via the Newcastle University Male Infertility Genomics DAC. File access: Data can be held in unencrypted files on an institutional compute system, with Unix user group read/write access for one or more appropriate groups but not Unix world read/write access behind a secure firewall. Laptops holding these data should have password protected logins and screenlocks (set to lock after 5 min of inactivity). If held on USB keys or other portable hard drives, the data must be encrypted. APPENDIX II – PROJECT DETAILS (to be completed by the Requestor) Details of dataset requested i.e., EGA Study and Dataset Accession Number Brief abstract of the Project in which the Data will be used (500 words max) All Individuals who the User Institution to be named as registered users Name of Registered User Email Job Title Supervisor* All Individuals that should have an account created at the EGA Name of Registered User Email Job Title APPENDIX III – PUBLICATION POLICY The Newcastle University Male Infertility Genomics DAC intend to publish the results of their analysis of this dataset and do not consider its deposition into public databases to be the equivalent of such publications. The Newcastle University Male Infertility Genomics DAC anticipate that the dataset could be useful to other qualified researchers for a variety of purposes. However, some areas of work are subject to a publication moratorium. The publication moratorium covers any publications (including oral communications) that describe the use of the dataset. For research papers, submission for publication should not occur until 6 months after these data were first made available on the relevant hosting database, unless the Newcastle University Male Infertility Genomics DAC has provided written consent to earlier submission. In any publications based on these data, please describe how the data can be accessed, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers (e.g., EGAS00000000029), and acknowledge its use in a form agreed by the User Institution with the Newcastle University Male Infertility Genomics DAC.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001005569 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005480935 cram 63.5 GB
EGAF00005480936 cram 55.5 GB
EGAF00005480937 cram 12.6 GB
EGAF00005480938 cram 13.2 GB
EGAF00005480939 cram 53.6 GB
EGAF00005480940 cram 18.8 GB
EGAF00005480941 cram 17.1 GB
EGAF00005480942 cram 14.7 GB
EGAF00005480943 cram 12.5 GB
EGAF00005480944 cram 15.3 GB
EGAF00005480945 cram 15.3 GB
EGAF00005480946 cram 13.5 GB
EGAF00005480947 cram 13.7 GB
EGAF00005480948 cram 11.9 GB
EGAF00005480949 cram 10.6 GB
EGAF00005480950 cram 12.7 GB
EGAF00005480951 cram 12.5 GB
EGAF00005480952 cram 15.5 GB
EGAF00005480953 cram 50.9 GB
EGAF00005480954 cram 39.0 GB
EGAF00005480955 crai 1.2 MB
EGAF00005480956 crai 1.4 MB
EGAF00005480957 crai 1.3 MB
EGAF00005480958 crai 1.2 MB
EGAF00005480959 crai 1.2 MB
EGAF00005480960 crai 1.1 MB
EGAF00005480961 crai 1.4 MB
EGAF00005480962 crai 2.0 MB
EGAF00005480963 crai 1.3 MB
EGAF00005480964 crai 1.4 MB
EGAF00005480965 crai 1.3 MB
EGAF00005480966 crai 2.3 MB
EGAF00005480967 crai 1.2 MB
EGAF00005480968 crai 1.4 MB
EGAF00005480969 crai 1.1 MB
EGAF00005480970 crai 2.0 MB
EGAF00005480971 crai 1.5 MB
EGAF00005480972 crai 1.5 MB
EGAF00005480973 crai 2.0 MB
EGAF00005480974 crai 1.1 MB
EGAF00005480975 cram 59.4 GB
EGAF00005480976 cram 12.4 GB
EGAF00005480977 cram 12.7 GB
EGAF00005480978 cram 13.3 GB
EGAF00005480979 cram 16.2 GB
EGAF00005480980 cram 14.8 GB
EGAF00005480981 cram 18.2 GB
EGAF00005480982 cram 13.2 GB
EGAF00005480983 cram 15.4 GB
EGAF00005480984 cram 16.7 GB
EGAF00005480985 cram 18.3 GB
EGAF00005480986 cram 15.1 GB
EGAF00005480987 cram 11.6 GB
EGAF00005480988 cram 21.7 GB
EGAF00005480989 cram 14.2 GB
EGAF00005480990 cram 14.3 GB
EGAF00005480991 cram 15.3 GB
EGAF00005480992 cram 16.7 GB
EGAF00005480993 cram 12.5 GB
EGAF00005480994 cram 18.6 GB
EGAF00005480995 cram 12.1 GB
EGAF00005480996 cram 12.1 GB
EGAF00005480997 cram 16.1 GB
EGAF00005480998 cram 15.3 GB
EGAF00005480999 cram 12.7 GB
EGAF00005481000 cram 16.7 GB
EGAF00005481001 cram 16.8 GB
EGAF00005481002 cram 14.0 GB
EGAF00005481003 cram 13.9 GB
EGAF00005481004 cram 16.3 GB
EGAF00005481005 cram 18.4 GB
EGAF00005481006 cram 46.9 GB
EGAF00005481007 cram 51.1 GB
EGAF00005481008 cram 55.4 GB
EGAF00005481009 cram 15.4 GB
EGAF00005481010 cram 14.6 GB
EGAF00005481011 cram 13.9 GB
EGAF00005481012 cram 15.1 GB
EGAF00005481013 cram 10.4 GB
EGAF00005481014 cram 12.1 GB
EGAF00005481015 cram 17.7 GB
EGAF00005481016 cram 16.0 GB
EGAF00005481017 cram 13.6 GB
EGAF00005481018 cram 21.9 GB
EGAF00005481019 cram 22.2 GB
EGAF00005481020 cram 13.5 GB
EGAF00005481021 cram 14.8 GB
EGAF00005481024 crai 1.2 MB
EGAF00005481025 crai 1.6 MB
EGAF00005481026 crai 1.3 MB
EGAF00005481027 crai 2.3 MB
EGAF00005481028 crai 1.2 MB
EGAF00005481029 crai 1.1 MB
EGAF00005481030 crai 1.3 MB
EGAF00005481031 crai 1.4 MB
EGAF00005481032 crai 1.5 MB
EGAF00005481033 crai 1.3 MB
EGAF00005481034 crai 1.0 MB
EGAF00005481035 crai 1.2 MB
EGAF00005481036 crai 1.4 MB
EGAF00005481037 crai 1.1 MB
EGAF00005481038 crai 1.4 MB
EGAF00005481039 crai 1.5 MB
EGAF00005481040 crai 1.4 MB
EGAF00005481041 crai 1.1 MB
EGAF00005481042 crai 1.1 MB
EGAF00005481043 crai 1.0 MB
EGAF00005481044 crai 1.2 MB
EGAF00005481045 crai 1.3 MB
EGAF00005481046 crai 1.4 MB
EGAF00005481047 crai 1.1 MB
EGAF00005481048 crai 1.2 MB
EGAF00005481049 crai 1.2 MB
EGAF00005481050 crai 1.2 MB
EGAF00005481051 crai 1.4 MB
EGAF00005481052 crai 1.1 MB
EGAF00005481053 crai 1.2 MB
EGAF00005481054 crai 1.3 MB
EGAF00005481055 crai 1.3 MB
EGAF00005481056 crai 1.8 MB
EGAF00005481057 crai 1.1 MB
EGAF00005481058 crai 2.0 MB
EGAF00005481059 crai 1.1 MB
EGAF00005481060 crai 2.3 MB
EGAF00005481061 crai 1.1 MB
EGAF00005481062 crai 1.3 MB
EGAF00005481063 crai 994.7 kB
EGAF00005481064 crai 1.4 MB
EGAF00005481065 crai 2.1 MB
EGAF00005481066 crai 1.3 MB
EGAF00005481067 crai 1.1 MB
EGAF00005481068 crai 1.5 MB
EGAF00005481069 crai 1.2 MB
EGAF00005481070 crai 1.1 MB
EGAF00005481071 cram 13.5 GB
EGAF00005481072 cram 14.1 GB
EGAF00005481073 cram 52.1 GB
EGAF00005481074 cram 51.5 GB
EGAF00005481075 cram 65.0 GB
EGAF00005481076 cram 15.0 GB
EGAF00005481077 cram 14.5 GB
EGAF00005481078 cram 12.7 GB
EGAF00005481079 cram 18.0 GB
EGAF00005481080 cram 16.8 GB
EGAF00005481081 cram 12.1 GB
EGAF00005481082 cram 19.8 GB
EGAF00005481083 cram 23.7 GB
EGAF00005481084 cram 22.2 GB
EGAF00005481085 cram 124.8 GB
EGAF00005481086 cram 152.2 GB
EGAF00005481087 cram 139.9 GB
EGAF00005481088 cram 16.9 GB
EGAF00005481089 cram 21.6 GB
EGAF00005481090 cram 21.9 GB
EGAF00005481091 cram 15.0 GB
EGAF00005481092 cram 18.1 GB
EGAF00005481093 cram 23.5 GB
EGAF00005481094 cram 13.8 GB
EGAF00005481095 cram 16.8 GB
EGAF00005481096 cram 17.7 GB
EGAF00005481097 cram 15.6 GB
EGAF00005481098 cram 14.4 GB
EGAF00005481099 cram 17.0 GB
EGAF00005481100 cram 13.3 GB
EGAF00005481101 cram 12.7 GB
EGAF00005481102 cram 13.4 GB
EGAF00005481103 cram 44.9 GB
EGAF00005481104 cram 34.3 GB
EGAF00005481105 cram 28.7 GB
EGAF00005481106 cram 12.4 GB
EGAF00005481107 cram 9.3 GB
EGAF00005481108 cram 14.4 GB
EGAF00005481109 cram 17.2 GB
EGAF00005481110 cram 18.2 GB
EGAF00005481111 cram 19.5 GB
EGAF00005481112 cram 12.6 GB
EGAF00005481113 cram 19.5 GB
EGAF00005481114 cram 12.6 GB
EGAF00005481115 cram 18.0 GB
EGAF00005481116 cram 17.7 GB
EGAF00005481117 cram 15.1 GB
EGAF00005481118 cram 14.2 GB
EGAF00005481119 cram 27.3 GB
EGAF00005481120 cram 16.6 GB
EGAF00005481121 cram 21.4 GB
EGAF00005481122 cram 20.6 GB
EGAF00005481123 cram 21.7 GB
EGAF00005481124 cram 19.8 GB
EGAF00005481125 cram 24.2 GB
EGAF00005481126 cram 13.4 GB
EGAF00005481127 cram 14.7 GB
EGAF00005481128 cram 10.7 GB
EGAF00005481129 cram 17.6 GB
EGAF00005481130 cram 48.5 GB
EGAF00005481131 cram 51.6 GB
EGAF00005481132 cram 33.3 GB
EGAF00005481133 cram 17.9 GB
EGAF00005481134 cram 16.9 GB
EGAF00005481141 crai 1.4 MB
EGAF00005481142 crai 1.5 MB
EGAF00005481143 crai 1.5 MB
EGAF00005481144 crai 1.8 MB
EGAF00005481145 crai 1.7 MB
EGAF00005481146 crai 1.9 MB
EGAF00005481147 crai 2.1 MB
EGAF00005481148 crai 1.6 MB
EGAF00005481149 crai 1.0 MB
EGAF00005481150 crai 1.3 MB
EGAF00005481151 crai 2.0 MB
EGAF00005481152 crai 1.1 MB
EGAF00005481153 crai 2.2 MB
EGAF00005481154 crai 1.4 MB
EGAF00005481155 crai 1.8 MB
EGAF00005481156 crai 1.3 MB
EGAF00005481157 crai 1.4 MB
EGAF00005481158 crai 1.3 MB
EGAF00005481159 crai 1.4 MB
EGAF00005481160 crai 1.6 MB
EGAF00005481161 crai 1.3 MB
EGAF00005481162 crai 1.4 MB
EGAF00005481163 crai 1.5 MB
EGAF00005481164 crai 1.3 MB
EGAF00005481165 crai 1.3 MB
EGAF00005481166 crai 1.3 MB
EGAF00005481167 crai 1.3 MB
EGAF00005481168 crai 1.9 MB
EGAF00005481169 crai 1.1 MB
EGAF00005481170 crai 1.5 MB
EGAF00005481171 crai 1.1 MB
EGAF00005481172 crai 1.4 MB
EGAF00005481173 crai 1.1 MB
EGAF00005481174 crai 1.5 MB
EGAF00005481175 crai 1.8 MB
EGAF00005481176 crai 1.7 MB
EGAF00005481177 crai 1.8 MB
EGAF00005481178 crai 1.3 MB
EGAF00005481179 crai 1.1 MB
EGAF00005481180 crai 3.5 MB
EGAF00005481181 crai 1.4 MB
EGAF00005481182 crai 1.5 MB
EGAF00005481183 crai 1.6 MB
EGAF00005481184 crai 1.5 MB
EGAF00005481185 crai 4.0 MB
EGAF00005481186 crai 4.3 MB
EGAF00005481187 crai 1.3 MB
EGAF00005481188 crai 1.5 MB
EGAF00005481189 crai 1.2 MB
EGAF00005481190 crai 1.5 MB
EGAF00005481191 crai 1.7 MB
EGAF00005481192 crai 1.0 MB
EGAF00005481193 crai 1.0 MB
EGAF00005481194 crai 1.1 MB
EGAF00005481195 crai 1.4 MB
EGAF00005481196 crai 1.5 MB
EGAF00005481197 crai 1.2 MB
EGAF00005481198 crai 1.8 MB
EGAF00005481199 crai 2.3 MB
EGAF00005481200 crai 1.2 MB
EGAF00005481201 crai 1.4 MB
EGAF00005481202 crai 2.0 MB
EGAF00005481203 crai 1.9 MB
EGAF00005481204 crai 1.2 MB
EGAF00005481211 cram 16.8 GB
EGAF00005481212 cram 14.3 GB
EGAF00005481213 cram 15.2 GB
EGAF00005481216 cram 10.5 GB
EGAF00005481219 cram 48.8 GB
EGAF00005481220 cram 46.8 GB
EGAF00005481221 cram 43.4 GB
EGAF00005481222 cram 15.0 GB
EGAF00005481223 cram 16.4 GB
EGAF00005481224 cram 9.7 GB
EGAF00005481225 cram 20.2 GB
EGAF00005481226 cram 14.7 GB
EGAF00005481227 cram 15.2 GB
EGAF00005481228 cram 43.5 GB
EGAF00005481229 cram 37.5 GB
EGAF00005481230 cram 45.8 GB
EGAF00005481231 cram 36.7 GB
EGAF00005481232 cram 10.7 GB
EGAF00005481233 cram 27.3 GB
EGAF00005481234 cram 24.0 GB
EGAF00005481235 cram 15.6 GB
EGAF00005481236 cram 31.5 GB
EGAF00005481237 cram 38.5 GB
EGAF00005481238 cram 58.2 GB
EGAF00005481239 cram 55.8 GB
EGAF00005481240 cram 59.1 GB
EGAF00005481241 cram 56.5 GB
EGAF00005481242 cram 54.3 GB
EGAF00005481243 cram 49.1 GB
EGAF00005481244 cram 53.5 GB
EGAF00005481245 cram 52.4 GB
EGAF00005481246 cram 57.3 GB
EGAF00005481247 cram 61.9 GB
EGAF00005481248 cram 56.2 GB
EGAF00005481249 cram 56.0 GB
EGAF00005481250 cram 67.3 GB
EGAF00005481251 cram 49.2 GB
EGAF00005481252 cram 55.0 GB
EGAF00005481253 cram 51.9 GB
EGAF00005481254 cram 55.5 GB
EGAF00005481255 cram 65.2 GB
EGAF00005481262 crai 1.2 MB
EGAF00005481263 crai 2.4 MB
EGAF00005481264 crai 1.7 MB
EGAF00005481265 crai 1.9 MB
EGAF00005481266 crai 2.0 MB
EGAF00005481267 crai 1.8 MB
EGAF00005481268 crai 2.1 MB
EGAF00005481269 crai 1.5 MB
EGAF00005481270 crai 2.3 MB
EGAF00005481271 crai 2.0 MB
EGAF00005481272 crai 1.8 MB
EGAF00005481273 crai 1.8 MB
EGAF00005481274 crai 1.1 MB
EGAF00005481275 crai 2.2 MB
EGAF00005481276 crai 2.3 MB
EGAF00005481277 crai 1.9 MB
EGAF00005481278 crai 1.9 MB
EGAF00005481279 crai 1.9 MB
EGAF00005481280 crai 2.0 MB
EGAF00005481281 crai 1.5 MB
EGAF00005481282 crai 2.6 MB
EGAF00005481283 crai 1.5 MB
EGAF00005481284 crai 930.9 kB
EGAF00005481285 crai 2.1 MB
EGAF00005481286 crai 1.9 MB
EGAF00005481287 crai 2.0 MB
EGAF00005481288 crai 2.0 MB
EGAF00005481289 crai 1.6 MB
EGAF00005481290 crai 1.1 MB
EGAF00005481291 crai 2.0 MB
EGAF00005481292 crai 1.4 MB
EGAF00005481293 crai 1.1 MB
EGAF00005481294 crai 2.1 MB
EGAF00005481295 crai 1.5 MB
EGAF00005481296 crai 2.4 MB
EGAF00005481297 crai 1.1 MB
EGAF00005481298 crai 1.6 MB
EGAF00005481299 crai 1.1 MB
EGAF00005481300 crai 1.8 MB
EGAF00005481301 crai 2.1 MB
EGAF00005481302 crai 1.7 MB
EGAF00005481303 cram 129.9 GB
EGAF00005481304 cram 155.7 GB
EGAF00005481305 cram 158.6 GB
EGAF00005481308 cram 48.5 GB
EGAF00005481309 cram 50.3 GB
EGAF00005481310 cram 50.1 GB
EGAF00005481311 cram 49.2 GB
EGAF00005481312 cram 48.9 GB
EGAF00005481313 cram 52.0 GB
EGAF00005481314 cram 41.5 GB
EGAF00005481315 cram 47.7 GB
EGAF00005481316 cram 40.1 GB
EGAF00005481317 cram 56.3 GB
EGAF00005481318 cram 50.7 GB
EGAF00005481319 cram 51.0 GB
EGAF00005481320 cram 53.4 GB
EGAF00005481321 cram 59.4 GB
EGAF00005481322 cram 58.3 GB
EGAF00005481343 cram 40.6 GB
EGAF00005481364 cram 38.7 GB
EGAF00005481385 cram 41.9 GB
EGAF00005481408 cram 48.8 GB
EGAF00005481419 cram 48.6 GB
EGAF00005481452 cram 57.1 GB
EGAF00005481473 cram 63.5 GB
EGAF00005481514 cram 36.8 GB
EGAF00005481523 cram 36.7 GB
EGAF00005481546 cram 51.9 GB
EGAF00005481567 cram 58.7 GB
EGAF00005481612 cram 56.4 GB
EGAF00005481629 cram 38.4 GB
EGAF00005481634 cram 38.3 GB
EGAF00005481651 cram 32.7 GB
EGAF00005481656 cram 46.0 GB
EGAF00005481661 cram 44.8 GB
EGAF00005481676 cram 31.3 GB
EGAF00005481689 cram 50.9 GB
EGAF00005481700 cram 41.4 GB
EGAF00005481719 cram 46.8 GB
EGAF00005481724 cram 50.8 GB
EGAF00005481727 cram 52.8 GB
EGAF00005481748 cram 44.8 GB
EGAF00005481749 cram 60.3 GB
EGAF00005481770 cram 65.5 GB
EGAF00005481771 cram 62.5 GB
EGAF00005481790 cram 48.2 GB
EGAF00005481795 cram 51.3 GB
EGAF00005481822 cram 46.1 GB
EGAF00005481835 cram 48.5 GB
EGAF00005481844 cram 33.8 GB
EGAF00005481859 cram 38.2 GB
EGAF00005481866 cram 39.0 GB
EGAF00005481881 cram 32.4 GB
EGAF00005481888 cram 39.1 GB
EGAF00005481893 cram 42.5 GB
EGAF00005481914 cram 14.6 GB
EGAF00005481937 cram 35.1 GB
EGAF00005481938 cram 37.8 GB
EGAF00005481959 cram 30.8 GB
EGAF00005481960 cram 41.0 GB
EGAF00005481977 cram 49.4 GB
EGAF00005481982 cram 40.2 GB
EGAF00005481987 cram 45.4 GB
EGAF00005482006 cram 48.7 GB
EGAF00005482009 cram 49.7 GB
EGAF00005482020 cram 46.0 GB
EGAF00005482031 cram 40.3 GB
EGAF00005482032 cram 28.9 GB
EGAF00005482037 cram 40.6 GB
EGAF00005482038 cram 52.9 GB
EGAF00005482053 cram 47.2 GB
EGAF00005482080 cram 55.9 GB
EGAF00005482101 cram 41.2 GB
EGAF00005482122 cram 47.9 GB
EGAF00005482123 cram 52.5 GB
EGAF00005482124 cram 43.2 GB
EGAF00005482125 cram 48.0 GB
EGAF00005482126 cram 49.7 GB
EGAF00005482127 cram 46.2 GB
EGAF00005482128 cram 50.1 GB
EGAF00005482129 cram 50.8 GB
EGAF00005482130 cram 14.1 GB
EGAF00005482131 cram 15.7 GB
EGAF00005482132 cram 22.9 GB
EGAF00005482133 cram 15.2 GB
EGAF00005482140 crai 2.0 MB
EGAF00005482141 crai 2.1 MB
EGAF00005482142 crai 1.7 MB
EGAF00005482143 crai 1.5 MB
EGAF00005482144 crai 2.0 MB
EGAF00005482145 crai 2.0 MB
EGAF00005482146 crai 1.2 MB
EGAF00005482147 crai 595.7 kB
EGAF00005482148 crai 1.9 MB
EGAF00005482149 crai 1.8 MB
EGAF00005482150 crai 2.3 MB
EGAF00005482151 crai 1.8 MB
EGAF00005482152 crai 1.5 MB
EGAF00005482153 crai 3.3 MB
EGAF00005482154 crai 2.2 MB
EGAF00005482155 crai 2.1 MB
EGAF00005482156 crai 1.7 MB
EGAF00005482157 crai 1.8 MB
EGAF00005482158 crai 1.6 MB
EGAF00005482159 crai 1.9 MB
EGAF00005482160 crai 1.8 MB
EGAF00005482161 crai 2.3 MB
EGAF00005482162 crai 1.7 MB
EGAF00005482163 crai 1.6 MB
EGAF00005482164 crai 1.7 MB
EGAF00005482165 crai 2.3 MB
EGAF00005482166 crai 1.6 MB
EGAF00005482167 crai 1.5 MB
EGAF00005482168 crai 2.0 MB
EGAF00005482169 crai 1.8 MB
EGAF00005482170 crai 1.8 MB
EGAF00005482171 crai 2.1 MB
EGAF00005482172 crai 1.3 MB
EGAF00005482173 crai 2.1 MB
EGAF00005482174 crai 1.8 MB
EGAF00005482175 crai 2.3 MB
EGAF00005482176 crai 1.2 MB
EGAF00005482177 crai 1.7 MB
EGAF00005482178 crai 1.8 MB
EGAF00005482179 crai 2.1 MB
EGAF00005482180 crai 1.6 MB
EGAF00005482181 crai 1.6 MB
EGAF00005482182 crai 4.3 MB
EGAF00005482183 crai 2.2 MB
EGAF00005482184 crai 1.5 MB
EGAF00005482185 crai 1.9 MB
EGAF00005482186 crai 1.2 MB
EGAF00005482187 crai 2.0 MB
EGAF00005482188 crai 1.6 MB
EGAF00005482189 crai 2.0 MB
EGAF00005482190 crai 2.0 MB
EGAF00005482191 crai 2.2 MB
EGAF00005482192 crai 1.6 MB
EGAF00005482193 crai 2.1 MB
EGAF00005482194 crai 2.1 MB
EGAF00005482195 crai 2.1 MB
EGAF00005482196 crai 1.7 MB
EGAF00005482197 crai 1.8 MB
EGAF00005482198 crai 1.7 MB
EGAF00005482199 crai 2.0 MB
EGAF00005482200 crai 2.4 MB
EGAF00005482201 crai 2.1 MB
EGAF00005482202 crai 2.0 MB
EGAF00005482203 crai 2.3 MB
EGAF00005482204 crai 1.8 MB
EGAF00005482205 crai 2.1 MB
EGAF00005482206 crai 2.1 MB
EGAF00005482207 crai 1.9 MB
EGAF00005482208 crai 2.3 MB
EGAF00005482209 crai 2.1 MB
EGAF00005482210 crai 1.5 MB
EGAF00005482211 crai 1.4 MB
EGAF00005482212 crai 4.0 MB
EGAF00005482213 crai 1.4 MB
EGAF00005482214 crai 2.1 MB
EGAF00005482215 crai 1.9 MB
EGAF00005482216 crai 2.0 MB
EGAF00005482217 crai 1.3 MB
EGAF00005482218 crai 1.4 MB
EGAF00005482219 crai 1.5 MB
EGAF00005482220 crai 1.5 MB
EGAF00005482221 crai 2.1 MB
EGAF00005482222 crai 2.1 MB
EGAF00005482223 crai 1.5 MB
EGAF00005482224 crai 2.4 MB
514 Files (8.8 TB)