Single-cell RNA-seq of patient-derived organoids across three generations

Single-cell RNA-seq of first-, second-, and third-generation patient-derived organoids. Obtained using the 10X Genomics single-cell 3' expression solution (v3 chemistry). First- and second-generation PDOs from one patient and first-, second-, and third-generation PDOs from three additional patients.

11 samples
DAC: EGAC00000000011
Technology: Illumina NovaSeq 6000

Access Policy1 Study Files

Metadata

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RU DUO:0000014 (version: 2019-01-07)research use onlyThis data use limitation indicates that use is limited to research purposes (e.g., does not include its use in clinical care).

BCCA (BCGSC) data policy

This document refers to the data set which has been submitted to the European Genome Archive (EGA) for the controlled access by legitimate academic institutions that have agreed to comply with the terms of a Data Access Agreement drafted by the British Columbia Cancer Agency Branch herein represented by the Technology Development Office of the Provincial Health Services Authority. There are a number of steps that a researcher must take to obtain access to this data and the process is overseen by the Technology Development Office - contact our general email address TDOadmin@phsa.ca

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID	Study Title	Study Type
EGAS00001005227	Single-cell landscapes of primary glioblastomas and matched organoids and cell lines reveal variable retention of inter- and intra-tumor heterogeneity	Other

ID	File Type	Size
EGAF00005742153	fastq.gz	4.0 GB
EGAF00005742154	fastq.gz	3.4 GB
EGAF00005742155	fastq.gz	3.8 GB
EGAF00005742156	fastq.gz	3.4 GB
EGAF00005742157	fastq.gz	3.5 GB
EGAF00005742158	fastq.gz	3.1 GB
EGAF00005742159	fastq.gz	3.9 GB
EGAF00005742160	fastq.gz	3.4 GB
EGAF00005742161	fastq.gz	4.0 GB
EGAF00005742162	fastq.gz	3.5 GB
EGAF00005742163	fastq.gz	3.9 GB
EGAF00005742164	fastq.gz	3.4 GB
EGAF00005742165	fastq.gz	3.9 GB
EGAF00005742166	fastq.gz	3.3 GB
EGAF00005742167	fastq.gz	3.8 GB
EGAF00005742168	fastq.gz	3.2 GB
EGAF00005742169	fastq.gz	3.4 GB
EGAF00005742170	fastq.gz	2.9 GB
EGAF00005742171	fastq.gz	3.6 GB
EGAF00005742172	fastq.gz	3.2 GB
EGAF00005742173	fastq.gz	3.7 GB
EGAF00005742174	fastq.gz	3.3 GB
EGAF00005742175	fastq.gz	3.8 GB
EGAF00005742176	fastq.gz	3.3 GB
EGAF00005742177	fastq.gz	3.6 GB
EGAF00005742178	fastq.gz	3.2 GB
EGAF00005742179	fastq.gz	3.3 GB
EGAF00005742180	fastq.gz	3.0 GB
EGAF00005742181	fastq.gz	3.7 GB
EGAF00005742182	fastq.gz	3.2 GB
EGAF00005742183	fastq.gz	3.8 GB
EGAF00005742184	fastq.gz	3.4 GB
EGAF00005742185	fastq.gz	3.7 GB
EGAF00005742186	fastq.gz	3.3 GB
EGAF00005742187	fastq.gz	3.6 GB
EGAF00005742188	fastq.gz	3.1 GB
EGAF00005742189	fastq.gz	3.6 GB
EGAF00005742190	fastq.gz	3.0 GB
EGAF00005742191	fastq.gz	3.2 GB
EGAF00005742192	fastq.gz	2.8 GB
EGAF00005742193	fastq.gz	3.4 GB
EGAF00005742194	fastq.gz	3.1 GB
EGAF00005742195	fastq.gz	3.6 GB
EGAF00005742196	fastq.gz	3.2 GB
EGAF00005742197	fastq.gz	3.9 GB
EGAF00005742198	fastq.gz	3.4 GB
EGAF00005742199	fastq.gz	3.7 GB
EGAF00005742200	fastq.gz	3.4 GB
EGAF00005742201	fastq.gz	3.4 GB
EGAF00005742202	fastq.gz	3.1 GB
EGAF00005742203	fastq.gz	3.8 GB
EGAF00005742204	fastq.gz	3.3 GB
EGAF00005742205	fastq.gz	3.9 GB
EGAF00005742206	fastq.gz	3.5 GB
EGAF00005742207	fastq.gz	3.8 GB
EGAF00005742208	fastq.gz	3.4 GB
EGAF00005742209	fastq.gz	3.7 GB
EGAF00005742210	fastq.gz	3.2 GB
EGAF00005742211	fastq.gz	3.7 GB
EGAF00005742212	fastq.gz	3.1 GB
EGAF00005742213	fastq.gz	3.3 GB
EGAF00005742214	fastq.gz	2.9 GB
EGAF00005742215	fastq.gz	3.5 GB
EGAF00005742216	fastq.gz	3.2 GB
EGAF00005742217	fastq.gz	3.7 GB
EGAF00005742218	fastq.gz	3.3 GB
EGAF00005742219	fastq.gz	3.6 GB
EGAF00005742220	fastq.gz	3.1 GB
EGAF00005742221	fastq.gz	3.5 GB
EGAF00005742222	fastq.gz	3.1 GB
EGAF00005742223	fastq.gz	3.2 GB
EGAF00005742224	fastq.gz	2.9 GB
EGAF00005742225	fastq.gz	3.6 GB
EGAF00005742226	fastq.gz	3.1 GB
EGAF00005742227	fastq.gz	3.6 GB
EGAF00005742228	fastq.gz	3.2 GB
EGAF00005742229	fastq.gz	3.5 GB
EGAF00005742230	fastq.gz	3.1 GB
EGAF00005742231	fastq.gz	3.5 GB
EGAF00005742232	fastq.gz	3.0 GB
EGAF00005742233	fastq.gz	3.4 GB
EGAF00005742234	fastq.gz	2.9 GB
EGAF00005742235	fastq.gz	3.1 GB
EGAF00005742236	fastq.gz	2.7 GB
EGAF00005742237	fastq.gz	3.3 GB
EGAF00005742238	fastq.gz	2.9 GB
EGAF00005742239	fastq.gz	3.4 GB
EGAF00005742240	fastq.gz	3.0 GB
88 Files (298.6 GB)