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Targeted Myeloid DNA-Panelsequencing, DKFZ

Targeted myeloid DNA-Panelsequencing from purified bone marrow blasts of 104 treatment naive AML patients from the discovery cohort. For more details, we refere to Jayavelu, Wolf, Buettner et al. Libraries were prepared from 40 ng DNA using the QIASeq Human Myeloid Neoplasms Panel (Qiagen) according to the manufacturer’s protocol. Samples were tagged with the QIAseq 96-Unique Dual Index Set A for Illumina platforms (Qiagen) to yield unique combinations of i5 and i7 barcodes for each sample. Sample fragment size distribution and concentration was estimated using the Agilent High Sensitivity DNA kit on a 2100 Bioanalyzer (Agilent). Samples were pooled in an equimolar fashion, denatured, and diluted to 1.5 pM according to Illumina’s recommendations. The diluted library was sequenced on a NextSeq 500 benchtop sequencer (Illumina) using NextSeq High Output cartridges. Demultiplexing was performed using the BaseSpace cloud platform (Illumina).

Request Access

DAP for genomic sequencing data generated as part of the "AML proteogenomic landscape" paper.

In requesting access to and retrieving data from this repository: 1. You agree to use the Data only for the advancement of medical research, according to the consent obtained from sample donors. 2. You agree not to use the data or any part thereof for the creation of products for sale or for any commercial purpose. 3. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 4. You agree not to attempt to link the data provided under this agreement to other information or archive data available for the data sets provided, even if access to that data has been formally granted to you, or it is freely available without restriction, without specific permission being sought from the relevent access committees. 5. You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others, except as necessary for data/safety monitoring or programme management. Should You wish to share the Data with a collaborator outwith the same Institution, the third party must make a separate application for access to the Data. 6. You agree to use the data for the approved purpose and project described in your application; use of the data for a new purpose or project will require a new application and approval. 7. You accept that Data will be reissued from time to time, with suitable versioning. If the reissue is at the request of sample donors and/or other ethical scrutiny, You will destroy earlier versions of the Data. 9. You agree to acknowledge in any work based in whole or part on the Data, the published paper from which the Data derives, the version of the data, and the role of the authors and the relevant primary collectors and their funders. Suitable wording is provided upon request. 10. You accept that the authors, represented by the data accessing committee, the original data creators, depositors or copyright holders, or the funders of the Data or any part of the Data supplied: a) bear no legal responsibility for the accuracy or comprehensiveness of the Data; and b) accept no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason. 11. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted. 12. You recognise that nothing in this agreement shall operate to transfer to the User Institution any intellectual property rights relating to the Data. The User Institution has the right to develop intellectual property based on comparisons with their own data. 13. You accept that this agreement will terminate immediately upon any breach of this agreement by You and You will be required to destroy any Data held. 14. You accept that it may be necessary for the authors, represented by the data accessing committee, or its appointed agent to alter the terms of this agreement from time to time in order to address new concerns. In this event, the authors, represented by the data accessing committee, or its appointed agent will contact You to inform You of any changes and You agree that Your continued use of the Data shall be dependent on the parties entering into a new version of the Agreement. 15. You agree that you will submit a report to the Data Access Committee, if requested, on completion of the agreed purpose. The Data Access Committee agrees to treat the report and all information, data, results, and conclusions contained within such report as confidential information belonging to the User Institution. 16. You accept that the Data is protected by and subject to international laws, including but not limited to the “Gendiagnostikgesetzt”, the EU General Data Protection Regulation (GDPR), and that You are responsible for ensuring compliance with any such applicable law. The Consortium Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures in countries that have no national laws comparable to that which pertain in the EU. 17. This agreement shall be construed, interpreted and governed by the laws of the Federal Republic of Germany and the European Union and shall be subject to the non-exclusive jurisdiction of the german and european courts.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001005950 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00005784904 fastq.gz 18.4 MB Report
EGAF00005784905 fastq.gz 20.1 MB Report
EGAF00005784906 fastq.gz 453.9 MB Report
EGAF00005784907 fastq.gz 488.5 MB Report
EGAF00005784908 fastq.gz 588.6 MB Report
EGAF00005784909 fastq.gz 646.5 MB Report
EGAF00005784910 fastq.gz 886.0 MB Report
EGAF00005784911 fastq.gz 959.3 MB Report
EGAF00005784912 fastq.gz 269.9 MB Report
EGAF00005784913 fastq.gz 290.2 MB Report
EGAF00005784914 fastq.gz 934.7 MB Report
EGAF00005784915 fastq.gz 1.0 GB Report
EGAF00005784916 fastq.gz 242.9 MB Report
EGAF00005784917 fastq.gz 267.7 MB Report
EGAF00005784918 fastq.gz 254.5 MB Report
EGAF00005784919 fastq.gz 282.0 MB Report
EGAF00005784920 fastq.gz 505.5 MB Report
EGAF00005784921 fastq.gz 556.2 MB Report
EGAF00005784922 fastq.gz 679.3 MB Report
EGAF00005784923 fastq.gz 747.6 MB Report
EGAF00005784924 fastq.gz 450.1 MB Report
EGAF00005784925 fastq.gz 484.6 MB Report
EGAF00005784926 fastq.gz 413.8 MB Report
EGAF00005784927 fastq.gz 444.7 MB Report
EGAF00005784928 fastq.gz 27.9 MB Report
EGAF00005784929 fastq.gz 30.7 MB Report
EGAF00005784930 fastq.gz 586.1 MB Report
EGAF00005784931 fastq.gz 644.0 MB Report
EGAF00005784932 fastq.gz 168.3 MB Report
EGAF00005784933 fastq.gz 182.1 MB Report
EGAF00005784934 fastq.gz 729.4 MB Report
EGAF00005784935 fastq.gz 808.3 MB Report
EGAF00005784936 fastq.gz 286.7 MB Report
EGAF00005784937 fastq.gz 311.0 MB Report
EGAF00005784938 fastq.gz 728.4 MB Report
EGAF00005784939 fastq.gz 808.7 MB Report
EGAF00005784940 fastq.gz 945.7 MB Report
EGAF00005784941 fastq.gz 1.0 GB Report
EGAF00005784942 fastq.gz 619.3 MB Report
EGAF00005784943 fastq.gz 682.0 MB Report
EGAF00005784944 fastq.gz 467.3 MB Report
EGAF00005784945 fastq.gz 513.2 MB Report
EGAF00005784946 fastq.gz 303.0 MB Report
EGAF00005784947 fastq.gz 335.6 MB Report
EGAF00005784948 fastq.gz 587.1 MB Report
EGAF00005784949 fastq.gz 632.8 MB Report
EGAF00005784950 fastq.gz 962.5 MB Report
EGAF00005784951 fastq.gz 1.1 GB Report
EGAF00005784952 fastq.gz 286.5 MB Report
EGAF00005784953 fastq.gz 310.1 MB Report
EGAF00005784954 fastq.gz 743.3 MB Report
EGAF00005784955 fastq.gz 821.4 MB Report
EGAF00005784956 fastq.gz 569.5 MB Report
EGAF00005784957 fastq.gz 628.8 MB Report
EGAF00005784958 fastq.gz 1.2 GB Report
EGAF00005784959 fastq.gz 1.3 GB Report
EGAF00005784960 fastq.gz 251.6 MB Report
EGAF00005784961 fastq.gz 277.7 MB Report
EGAF00005784962 fastq.gz 506.6 MB Report
EGAF00005784963 fastq.gz 525.3 MB Report
EGAF00005784964 fastq.gz 748.3 MB Report
EGAF00005784965 fastq.gz 822.7 MB Report
EGAF00005784966 fastq.gz 854.0 MB Report
EGAF00005784967 fastq.gz 48.3 MB
EGAF00005784968 fastq.gz 64.9 MB Report
EGAF00005784969 fastq.gz 70.9 MB Report
EGAF00005784970 fastq.gz 2.7 GB Report
EGAF00005784971 fastq.gz 2.9 GB Report
EGAF00005784972 fastq.gz 750.1 MB Report
EGAF00005784973 fastq.gz 828.4 MB Report
EGAF00005784974 fastq.gz 362.7 MB Report
EGAF00005784975 fastq.gz 399.7 MB Report
EGAF00005784976 fastq.gz 1.6 GB Report
EGAF00005784977 fastq.gz 1.8 GB Report
EGAF00005784978 fastq.gz 685.8 MB Report
EGAF00005784979 fastq.gz 712.6 MB Report
EGAF00005784980 fastq.gz 1.3 GB Report
EGAF00005784981 fastq.gz 1.4 GB Report
EGAF00005784982 fastq.gz 353.3 MB Report
EGAF00005784983 fastq.gz 380.5 MB Report
EGAF00005784984 fastq.gz 726.2 MB Report
EGAF00005784985 fastq.gz 797.6 MB Report
EGAF00005784986 fastq.gz 2.1 GB Report
EGAF00005784987 fastq.gz 2.3 GB Report
EGAF00005784988 fastq.gz 393.2 MB Report
EGAF00005784989 fastq.gz 424.8 MB Report
EGAF00005784990 fastq.gz 730.8 MB Report
EGAF00005784991 fastq.gz 801.7 MB Report
EGAF00005784992 fastq.gz 1.4 GB Report
EGAF00005784993 fastq.gz 1.4 GB Report
EGAF00005784994 fastq.gz 351.3 MB Report
EGAF00005784995 fastq.gz 378.3 MB Report
EGAF00005784996 fastq.gz 535.3 MB Report
EGAF00005784997 fastq.gz 556.8 MB Report
EGAF00005784998 fastq.gz 1.1 GB Report
EGAF00005784999 fastq.gz 1.1 GB Report
EGAF00005785000 fastq.gz 298.2 MB Report
EGAF00005785001 fastq.gz 309.5 MB Report
EGAF00005785002 fastq.gz 200.1 MB Report
EGAF00005785003 fastq.gz 216.0 MB Report
EGAF00005785004 fastq.gz 150.2 MB Report
EGAF00005785005 fastq.gz 165.6 MB Report
EGAF00005785006 fastq.gz 399.4 MB Report
EGAF00005785007 fastq.gz 440.7 MB Report
EGAF00005785008 fastq.gz 1.9 GB Report
EGAF00005785009 fastq.gz 2.0 GB Report
EGAF00005785010 fastq.gz 308.7 MB Report
EGAF00005785011 fastq.gz 320.0 MB Report
EGAF00005785012 fastq.gz 286.9 MB Report
EGAF00005785013 fastq.gz 297.4 MB Report
EGAF00005785014 fastq.gz 315.3 MB Report
EGAF00005785015 fastq.gz 347.2 MB Report
EGAF00005785016 fastq.gz 798.8 MB Report
EGAF00005785017 fastq.gz 880.6 MB Report
EGAF00005785018 fastq.gz 862.7 MB Report
EGAF00005785019 fastq.gz 895.6 MB Report
EGAF00005785020 fastq.gz 1.8 GB Report
EGAF00005785021 fastq.gz 1.8 GB Report
EGAF00005785022 fastq.gz 1.1 GB Report
EGAF00005785023 fastq.gz 1.2 GB Report
EGAF00005785024 fastq.gz 983.3 MB Report
EGAF00005785025 fastq.gz 1.1 GB Report
EGAF00005785026 fastq.gz 414.4 MB Report
EGAF00005785027 fastq.gz 429.8 MB Report
EGAF00005785028 fastq.gz 785.9 MB Report
EGAF00005785029 fastq.gz 866.6 MB Report
EGAF00005785030 fastq.gz 332.6 MB Report
EGAF00005785031 fastq.gz 362.1 MB Report
EGAF00005785032 fastq.gz 945.6 MB Report
EGAF00005785033 fastq.gz 1.0 GB Report
EGAF00005785034 fastq.gz 472.9 MB Report
EGAF00005785035 fastq.gz 492.5 MB Report
EGAF00005785036 fastq.gz 212.0 MB Report
EGAF00005785037 fastq.gz 233.0 MB Report
EGAF00005785038 fastq.gz 739.2 MB Report
EGAF00005785039 fastq.gz 812.5 MB Report
EGAF00005785040 fastq.gz 730.8 MB Report
EGAF00005785041 fastq.gz 800.7 MB Report
EGAF00005785042 fastq.gz 948.7 MB Report
EGAF00005785043 fastq.gz 1.0 GB Report
EGAF00005785044 fastq.gz 650.5 MB Report
EGAF00005785045 fastq.gz 704.8 MB Report
EGAF00005785046 fastq.gz 375.4 MB Report
EGAF00005785047 fastq.gz 413.5 MB Report
EGAF00005785048 fastq.gz 691.3 MB Report
EGAF00005785049 fastq.gz 760.0 MB Report
EGAF00005785050 fastq.gz 439.2 MB Report
EGAF00005785051 fastq.gz 462.9 MB Report
EGAF00005785052 fastq.gz 260.1 MB Report
EGAF00005785053 fastq.gz 270.1 MB Report
EGAF00005785054 fastq.gz 1.3 GB Report
EGAF00005785055 fastq.gz 1.4 GB Report
EGAF00005785056 fastq.gz 2.0 GB Report
EGAF00005785057 fastq.gz 2.2 GB Report
EGAF00005785058 fastq.gz 398.4 MB Report
EGAF00005785059 fastq.gz 429.2 MB Report
EGAF00005785060 fastq.gz 626.5 MB Report
EGAF00005785061 fastq.gz 678.1 MB Report
EGAF00005785062 fastq.gz 2.4 GB Report
EGAF00005785063 fastq.gz 2.7 GB Report
EGAF00005785064 fastq.gz 399.6 MB Report
EGAF00005785065 fastq.gz 431.0 MB Report
EGAF00005785066 fastq.gz 462.5 MB Report
EGAF00005785067 fastq.gz 479.9 MB Report
EGAF00005785068 fastq.gz 280.6 MB Report
EGAF00005785069 fastq.gz 291.0 MB Report
EGAF00005785070 fastq.gz 189.8 MB Report
EGAF00005785071 fastq.gz 204.5 MB Report
EGAF00005785072 fastq.gz 310.2 MB Report
EGAF00005785073 fastq.gz 335.0 MB Report
EGAF00005785074 fastq.gz 558.3 MB Report
EGAF00005785075 fastq.gz 616.5 MB Report
EGAF00005785076 fastq.gz 340.6 MB Report
EGAF00005785077 fastq.gz 367.1 MB Report
EGAF00005785078 fastq.gz 251.7 MB Report
EGAF00005785079 fastq.gz 276.9 MB Report
EGAF00005785080 fastq.gz 302.6 MB Report
EGAF00005785081 fastq.gz 314.5 MB Report
EGAF00005785082 fastq.gz 377.9 MB Report
EGAF00005785083 fastq.gz 417.6 MB Report
EGAF00005785084 fastq.gz 235.7 MB Report
EGAF00005785085 fastq.gz 254.7 MB Report
EGAF00005785086 fastq.gz 257.1 MB Report
EGAF00005785087 fastq.gz 289.2 MB Report
EGAF00005785088 fastq.gz 322.1 MB Report
EGAF00005785089 fastq.gz 349.4 MB Report
EGAF00005785090 fastq.gz 706.4 MB Report
EGAF00005785091 fastq.gz 779.2 MB Report
EGAF00005785092 fastq.gz 264.5 MB Report
EGAF00005785093 fastq.gz 274.5 MB Report
EGAF00005785094 fastq.gz 221.6 MB Report
EGAF00005785095 fastq.gz 245.0 MB Report
EGAF00005785096 fastq.gz 348.4 MB Report
EGAF00005785097 fastq.gz 382.3 MB Report
EGAF00005785098 fastq.gz 511.0 MB Report
EGAF00005785099 fastq.gz 562.7 MB Report
EGAF00005785100 fastq.gz 403.4 MB Report
EGAF00005785101 fastq.gz 441.2 MB Report
EGAF00005785102 fastq.gz 950.7 MB Report
EGAF00005785103 fastq.gz 1.0 GB Report
EGAF00005785104 fastq.gz 338.2 MB Report
EGAF00005785105 fastq.gz 351.8 MB Report
EGAF00005785106 fastq.gz 719.6 MB Report
EGAF00005785107 fastq.gz 794.0 MB Report
EGAF00005785108 fastq.gz 949.5 MB Report
EGAF00005785109 fastq.gz 1.0 GB Report
EGAF00005785110 fastq.gz 176.7 MB Report
EGAF00005785111 fastq.gz 193.9 MB Report
EGAF00005785112 xlsx 1.7 MB
EGAF00007020925 fastq.gz 942.9 MB Report
210 Files (138.4 GB)