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Transcriptome analysis for intrahepatic cholangiocarcinoma

Intrahepatic cholangiocarcinomas (iCCs) are characterized by their rarity, difficulty in diagnosis, and overall poor prognosis. We performed comprehensive transcriptomic characterization of treatment-naive iCC. Whole transcriptome analyses identified two prognostic subtypes, concordant with previous reports.The findings could assist in patient stratification with iCCs and in developing rational therapeutic strategies.

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DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions.

Definitions Authorised Personnel: The individuals at the User Institution to whom NCC grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: NCC and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. NCC: National Cancer Center. The Institution of the principal investigator. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify NCC within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify NCC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify NCC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. NCC may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than NCC. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of England and Wales and shall be subject to the exclusive jurisdiction of the English courts.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006007 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005797081 fastq.gz 5.1 GB
EGAF00005797082 fastq.gz 5.5 GB
EGAF00005797083 fastq.gz 4.7 GB
EGAF00005797084 fastq.gz 4.8 GB
EGAF00005797085 fastq.gz 5.0 GB
EGAF00005797086 fastq.gz 5.3 GB
EGAF00005797087 fastq.gz 5.4 GB
EGAF00005797088 fastq.gz 5.5 GB
EGAF00005797089 fastq.gz 4.5 GB
EGAF00005797090 fastq.gz 4.7 GB
EGAF00005797091 fastq.gz 5.9 GB
EGAF00005797092 fastq.gz 6.3 GB
EGAF00005797093 fastq.gz 5.0 GB
EGAF00005797094 fastq.gz 5.2 GB
EGAF00005797095 fastq.gz 5.1 GB
EGAF00005797096 fastq.gz 5.2 GB
EGAF00005797097 fastq.gz 4.9 GB
EGAF00005797098 fastq.gz 5.0 GB
EGAF00005797099 fastq.gz 5.0 GB
EGAF00005797100 fastq.gz 5.0 GB
EGAF00005797101 fastq.gz 5.2 GB
EGAF00005797102 fastq.gz 5.3 GB
EGAF00005797103 fastq.gz 4.9 GB
EGAF00005797104 fastq.gz 5.1 GB
EGAF00005797105 fastq.gz 5.2 GB
EGAF00005797106 fastq.gz 5.5 GB
EGAF00005797107 fastq.gz 5.5 GB
EGAF00005797108 fastq.gz 5.6 GB
EGAF00005797109 fastq.gz 5.1 GB
EGAF00005797110 fastq.gz 5.1 GB
EGAF00005797111 fastq.gz 5.1 GB
EGAF00005797112 fastq.gz 5.2 GB
EGAF00005797113 fastq.gz 4.7 GB
EGAF00005797114 fastq.gz 4.8 GB
EGAF00005797115 fastq.gz 5.1 GB
EGAF00005797116 fastq.gz 5.2 GB
EGAF00005797117 fastq.gz 5.1 GB
EGAF00005797118 fastq.gz 5.6 GB
EGAF00005797119 fastq.gz 5.4 GB
EGAF00005797120 fastq.gz 5.6 GB
EGAF00005797121 fastq.gz 5.5 GB
EGAF00005797122 fastq.gz 5.9 GB
EGAF00005797123 fastq.gz 4.7 GB
EGAF00005797124 fastq.gz 5.0 GB
EGAF00005797125 fastq.gz 4.5 GB
EGAF00005797126 fastq.gz 4.8 GB
EGAF00005797127 fastq.gz 4.6 GB
EGAF00005797128 fastq.gz 4.7 GB
EGAF00005797129 fastq.gz 5.4 GB
EGAF00005797130 fastq.gz 5.5 GB
EGAF00005797131 fastq.gz 4.5 GB
EGAF00005797132 fastq.gz 4.6 GB
EGAF00005797133 fastq.gz 4.9 GB
EGAF00005797134 fastq.gz 4.9 GB
EGAF00005797135 fastq.gz 5.0 GB
EGAF00005797136 fastq.gz 5.2 GB
EGAF00005797137 fastq.gz 5.2 GB
EGAF00005797138 fastq.gz 5.3 GB
EGAF00005797139 fastq.gz 7.3 GB
EGAF00005797140 fastq.gz 7.8 GB
EGAF00005797141 fastq.gz 4.5 GB
EGAF00005797142 fastq.gz 4.6 GB
EGAF00005797143 fastq.gz 5.0 GB
EGAF00005797144 fastq.gz 5.2 GB
EGAF00005797145 fastq.gz 5.3 GB
EGAF00005797146 fastq.gz 5.5 GB
EGAF00005797147 fastq.gz 5.4 GB
EGAF00005797148 fastq.gz 5.5 GB
EGAF00005797149 fastq.gz 4.3 GB
EGAF00005797150 fastq.gz 4.6 GB
EGAF00005797151 fastq.gz 6.3 GB
EGAF00005797152 fastq.gz 6.4 GB
EGAF00005797153 fastq.gz 4.9 GB
EGAF00005797154 fastq.gz 5.1 GB
EGAF00005797155 fastq.gz 4.6 GB
EGAF00005797156 fastq.gz 4.7 GB
EGAF00005797157 fastq.gz 5.4 GB
EGAF00005797158 fastq.gz 5.5 GB
EGAF00005797159 fastq.gz 4.8 GB
EGAF00005797160 fastq.gz 4.9 GB
EGAF00005797161 fastq.gz 4.3 GB
EGAF00005797162 fastq.gz 4.5 GB
EGAF00005797163 fastq.gz 5.2 GB
EGAF00005797164 fastq.gz 5.2 GB
EGAF00005797165 fastq.gz 4.4 GB
EGAF00005797166 fastq.gz 4.4 GB
EGAF00005797167 fastq.gz 5.7 GB
EGAF00005797168 fastq.gz 5.8 GB
EGAF00005797169 fastq.gz 4.9 GB
EGAF00005797170 fastq.gz 5.2 GB
EGAF00005797171 fastq.gz 4.9 GB
EGAF00005797172 fastq.gz 5.1 GB
EGAF00005797173 fastq.gz 5.7 GB
EGAF00005797174 fastq.gz 5.8 GB
EGAF00005797175 fastq.gz 5.6 GB
EGAF00005797176 fastq.gz 5.7 GB
EGAF00005797177 fastq.gz 5.0 GB
EGAF00005797178 fastq.gz 5.2 GB
EGAF00005797179 fastq.gz 4.3 GB
EGAF00005797180 fastq.gz 4.5 GB
EGAF00005797181 fastq.gz 5.8 GB
EGAF00005797182 fastq.gz 6.1 GB
EGAF00005797183 fastq.gz 5.4 GB
EGAF00005797184 fastq.gz 5.5 GB
EGAF00005797185 fastq.gz 5.0 GB
EGAF00005797186 fastq.gz 5.2 GB
EGAF00005797187 fastq.gz 4.9 GB
EGAF00005797188 fastq.gz 5.2 GB
EGAF00005797189 fastq.gz 5.0 GB
EGAF00005797190 fastq.gz 5.2 GB
EGAF00005797191 fastq.gz 5.1 GB
EGAF00005797192 fastq.gz 5.2 GB
EGAF00005797193 fastq.gz 4.5 GB
EGAF00005797194 fastq.gz 4.7 GB
EGAF00005797195 fastq.gz 4.8 GB
EGAF00005797196 fastq.gz 5.0 GB
EGAF00005797197 fastq.gz 5.3 GB
EGAF00005797198 fastq.gz 5.3 GB
EGAF00005797199 fastq.gz 5.2 GB
EGAF00005797200 fastq.gz 5.2 GB
EGAF00005797201 fastq.gz 4.8 GB
EGAF00005797202 fastq.gz 5.1 GB
EGAF00005797203 fastq.gz 5.6 GB
EGAF00005797204 fastq.gz 5.9 GB
EGAF00005797205 fastq.gz 4.8 GB
EGAF00005797206 fastq.gz 5.1 GB
EGAF00005797207 fastq.gz 6.0 GB
EGAF00005797208 fastq.gz 6.1 GB
EGAF00005797209 fastq.gz 4.6 GB
EGAF00005797210 fastq.gz 4.8 GB
EGAF00005797211 fastq.gz 5.1 GB
EGAF00005797212 fastq.gz 5.3 GB
EGAF00005797213 fastq.gz 5.5 GB
EGAF00005797214 fastq.gz 5.7 GB
EGAF00005797215 fastq.gz 4.4 GB
EGAF00005797216 fastq.gz 4.5 GB
EGAF00005797217 fastq.gz 5.0 GB
EGAF00005797218 fastq.gz 5.1 GB
EGAF00005797219 fastq.gz 5.2 GB
EGAF00005797220 fastq.gz 5.4 GB
EGAF00005797221 fastq.gz 5.2 GB
EGAF00005797222 fastq.gz 5.4 GB
EGAF00005797223 fastq.gz 5.4 GB
EGAF00005797224 fastq.gz 5.5 GB
EGAF00005797225 fastq.gz 5.8 GB
EGAF00005797226 fastq.gz 5.9 GB
EGAF00005797227 fastq.gz 4.9 GB
EGAF00005797228 fastq.gz 4.9 GB
EGAF00005797229 fastq.gz 4.9 GB
EGAF00005797230 fastq.gz 5.0 GB
EGAF00005797231 fastq.gz 5.3 GB
EGAF00005797232 fastq.gz 5.4 GB
EGAF00005797233 fastq.gz 5.3 GB
EGAF00005797234 fastq.gz 5.6 GB
EGAF00005797235 fastq.gz 4.7 GB
EGAF00005797236 fastq.gz 4.8 GB
EGAF00005797237 fastq.gz 5.1 GB
EGAF00005797238 fastq.gz 5.3 GB
EGAF00005797239 fastq.gz 4.7 GB
EGAF00005797240 fastq.gz 4.9 GB
EGAF00005797241 fastq.gz 5.7 GB
EGAF00005797242 fastq.gz 6.0 GB
EGAF00005797243 fastq.gz 5.0 GB
EGAF00005797244 fastq.gz 5.2 GB
EGAF00005797245 fastq.gz 5.1 GB
EGAF00005797246 fastq.gz 5.2 GB
EGAF00005797247 fastq.gz 4.6 GB
EGAF00005797248 fastq.gz 4.6 GB
EGAF00005797249 fastq.gz 5.3 GB
EGAF00005797250 fastq.gz 5.4 GB
EGAF00005797251 fastq.gz 5.2 GB
EGAF00005797252 fastq.gz 5.5 GB
EGAF00005797253 fastq.gz 5.5 GB
EGAF00005797254 fastq.gz 5.6 GB
EGAF00005797255 fastq.gz 4.3 GB
EGAF00005797256 fastq.gz 4.6 GB
EGAF00005797257 fastq.gz 5.7 GB
EGAF00005797258 fastq.gz 6.0 GB
EGAF00005797259 fastq.gz 6.1 GB
EGAF00005797260 fastq.gz 6.3 GB
EGAF00005797261 fastq.gz 4.7 GB
EGAF00005797262 fastq.gz 4.8 GB
182 Files (945.2 GB)