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A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours

We generated a single-cell RNA-seq atlas capturing over 100,000 cells spanning all stages of the mouse cerebral development. By examining data from over 100 cerebral tumour samples, our study reveals that, despite the phenotypic/genotypic differences between the tumour types, they are all comprised of developmental sublineages that map most closely to embryonic or juvenile stages of development.

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Single-cell RNA sequencing data from supratentorial ependymoma tumours generated by MDT lab in Hospital for Sick Children.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006237 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006158611 bam 10.2 GB
EGAF00006158612 bam 30.7 GB
EGAF00006158613 bam 27.1 GB
EGAF00006158614 bam 23.2 GB
4 Files (91.2 GB)