About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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RNA-seq derived from metastatic Castration-Resistant Prostate Cancer

Patients with progressive, metastatic castration-resistant prostate cancer (mCRPC) underwent metastatic tumor biopsy. 118 total samples including 14 paired samples (baseline and later progression). Various organ sites including soft tissue & bone were present. Published in DOI: 10.1200/JCO.2017.77.6880 Journal of Clinical Oncology 36, no. 24 (August 20, 2018) 2492-2503.

Request Access

Data Access Committee for SU2C data

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom the SU2C/PCF West Coast Dream Team Project grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: The SU2C/PCF West Coast Dream Team Project and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify the SU2C/PCF West Coast Dream Team Project within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify the SU2C/PCF West Coast Dream Team Project prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the SU2C/PCF West Coast Dream Team Project as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. The SU2C/PCF West Coast Dream Team Project may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than the SU2C/PCF West Coast Dream Team Project. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of the United States of America the American courts. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for SU2C/PCF West Coast Dream Team Project Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY APPENDIX I – DATASET DETAILS Dataset reference (EGA Study ID and Dataset Details) RNA-seq analysis of metastatic prostate cancer solid tumor biopsies Name of project that created the dataset University of California, San Francisco; Stand-up 2 Cancer/Prostate Cancer Foundation West Coast Dream Team studying metastatic Castration Resistant Prostate Cancer Names of other data producers/collaborators Not Applicable Specific limitations on areas of research None Minimum protection measures required File access: Data can be held in unencrypted files on an institutional compute system, with Unix user group read/write access for one or more appropriate groups but not Unix world read/write access behind a secure firewall. Laptops holding these data should have password protected logins and screenlocks (set to lock after 5 min of inactivity). If held on USB keys or other portable hard drives, the data must be encrypted. APPENDIX II – PROJECT DETAILS (to be completed by the Requestor) Details of dataset requested i.e., EGA Study and Dataset Accession Number Brief abstract of the Project in which the Data will be used (500 words max) All Individuals who the User Institution to be named as registered users Name of Registered User Email Job Title Supervisor* All Individuals that should have an account created at the EGA Name of Registered User Email Job Title APPENDIX III – PUBLICATION POLICY The SU2C/PCF West Coast Dream Team Project intend to publish the results of their analysis of this dataset and do not consider its deposition into public databases to be the equivalent of such publications. The SU2C/PCF West Coast Dream Team Project anticipate that the dataset could be useful to other qualified researchers for a variety of purposes. However, some areas of work are subject to a publication moratorium. The publication moratorium covers any publications (including oral communications) that describe the use of the dataset. For research papers, submission for publication should not occur until 3 months after these data were first made available on the relevant hosting database, unless the SU2C/PCF West Coast Dream Team Project has provided written consent to earlier submission. In any publications based on these data, please describe how the data can be accessed, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers (e.g., EGAS00000000029), and acknowledge its use in a form agreed by the User Institution with the SU2C/PCF West Coast Dream Team Project.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006369 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF00006219717 fastq.gz 5.0 GB Report
EGAF00006219718 fastq.gz 5.0 GB Report
EGAF00006219719 fastq.gz 4.6 GB Report
EGAF00006219720 fastq.gz 4.8 GB Report
EGAF00006219721 fastq.gz 7.1 GB Report
EGAF00006219722 fastq.gz 6.8 GB Report
EGAF00006219723 fastq.gz 4.7 GB Report
EGAF00006219724 fastq.gz 4.7 GB Report
EGAF00006219725 fastq.gz 4.7 GB Report
EGAF00006219726 fastq.gz 4.8 GB Report
EGAF00006219727 fastq.gz 5.9 GB Report
EGAF00006219728 fastq.gz 6.5 GB Report
EGAF00006219729 fastq.gz 4.7 GB Report
EGAF00006219730 fastq.gz 4.7 GB Report
EGAF00006219731 fastq.gz 4.3 GB Report
EGAF00006219732 fastq.gz 4.5 GB Report
EGAF00006219733 fastq.gz 4.3 GB Report
EGAF00006219734 fastq.gz 4.5 GB Report
EGAF00006219735 fastq.gz 8.0 GB Report
EGAF00006219736 fastq.gz 7.8 GB Report
EGAF00006219737 fastq.gz 5.0 GB Report
EGAF00006219738 fastq.gz 5.1 GB Report
EGAF00006219739 fastq.gz 4.2 GB Report
EGAF00006219740 fastq.gz 4.2 GB Report
EGAF00006219741 fastq.gz 8.1 GB Report
EGAF00006219742 fastq.gz 8.2 GB Report
EGAF00006219743 fastq.gz 3.9 GB Report
EGAF00006219744 fastq.gz 4.1 GB Report
EGAF00006219745 fastq.gz 5.4 GB Report
EGAF00006219746 fastq.gz 5.4 GB Report
EGAF00006219747 fastq.gz 3.4 GB Report
EGAF00006219748 fastq.gz 3.7 GB Report
EGAF00006219749 fastq.gz 4.0 GB Report
EGAF00006219750 fastq.gz 4.2 GB Report
EGAF00006219751 fastq.gz 4.7 GB Report
EGAF00006219752 fastq.gz 4.9 GB Report
EGAF00006219753 fastq.gz 5.9 GB Report
EGAF00006219754 fastq.gz 6.0 GB Report
EGAF00006219755 fastq.gz 5.8 GB Report
EGAF00006219756 fastq.gz 5.8 GB Report
EGAF00006219757 fastq.gz 2.5 GB Report
EGAF00006219758 fastq.gz 2.6 GB Report
EGAF00006219759 fastq.gz 4.4 GB Report
EGAF00006219760 fastq.gz 4.6 GB Report
EGAF00006219761 fastq.gz 3.1 GB Report
EGAF00006219762 fastq.gz 3.1 GB Report
EGAF00006219763 fastq.gz 5.8 GB Report
EGAF00006219764 fastq.gz 5.8 GB Report
EGAF00006219765 fastq.gz 4.0 GB Report
EGAF00006219766 fastq.gz 4.2 GB Report
EGAF00006219767 fastq.gz 4.8 GB Report
EGAF00006219768 fastq.gz 5.0 GB Report
EGAF00006219769 fastq.gz 5.5 GB Report
EGAF00006219770 fastq.gz 5.5 GB Report
EGAF00006219771 fastq.gz 5.2 GB Report
EGAF00006219772 fastq.gz 5.4 GB Report
EGAF00006219773 fastq.gz 3.7 GB Report
EGAF00006219774 fastq.gz 4.0 GB Report
EGAF00006219775 fastq.gz 3.3 GB Report
EGAF00006219776 fastq.gz 3.3 GB Report
EGAF00006219777 fastq.gz 6.1 GB Report
EGAF00006219778 fastq.gz 6.1 GB Report
EGAF00006219779 fastq.gz 4.8 GB Report
EGAF00006219780 fastq.gz 5.0 GB Report
EGAF00006219781 fastq.gz 3.9 GB Report
EGAF00006219782 fastq.gz 3.9 GB Report
EGAF00006219783 fastq.gz 4.1 GB Report
EGAF00006219784 fastq.gz 4.0 GB Report
EGAF00006219785 fastq.gz 5.7 GB Report
EGAF00006219786 fastq.gz 5.7 GB Report
EGAF00006219787 fastq.gz 4.0 GB Report
EGAF00006219788 fastq.gz 4.2 GB Report
EGAF00006219789 fastq.gz 4.3 GB Report
EGAF00006219790 fastq.gz 4.4 GB Report
EGAF00006219791 fastq.gz 4.9 GB Report
EGAF00006219792 fastq.gz 5.1 GB Report
EGAF00006219793 fastq.gz 4.6 GB Report
EGAF00006219794 fastq.gz 4.6 GB Report
EGAF00006219795 fastq.gz 4.7 GB Report
EGAF00006219796 fastq.gz 4.7 GB Report
EGAF00006219797 fastq.gz 4.8 GB Report
EGAF00006219798 fastq.gz 5.0 GB Report
EGAF00006219799 fastq.gz 3.7 GB Report
EGAF00006219800 fastq.gz 3.7 GB Report
EGAF00006219801 fastq.gz 4.6 GB Report
EGAF00006219802 fastq.gz 4.6 GB Report
EGAF00006219803 fastq.gz 6.0 GB Report
EGAF00006219804 fastq.gz 6.0 GB Report
EGAF00006219805 fastq.gz 5.1 GB Report
EGAF00006219806 fastq.gz 5.2 GB Report
EGAF00006219807 fastq.gz 5.3 GB Report
EGAF00006219808 fastq.gz 5.4 GB Report
EGAF00006219809 fastq.gz 4.4 GB Report
EGAF00006219810 fastq.gz 4.8 GB Report
EGAF00006219811 fastq.gz 4.7 GB Report
EGAF00006219812 fastq.gz 4.7 GB Report
EGAF00006219813 fastq.gz 4.4 GB Report
EGAF00006219814 fastq.gz 4.6 GB Report
EGAF00006219815 fastq.gz 4.3 GB Report
EGAF00006219816 fastq.gz 4.3 GB Report
EGAF00006219817 fastq.gz 8.9 GB Report
EGAF00006219818 fastq.gz 8.8 GB Report
EGAF00006219819 fastq.gz 4.6 GB Report
EGAF00006219820 fastq.gz 4.8 GB Report
EGAF00006219821 fastq.gz 4.0 GB Report
EGAF00006219822 fastq.gz 3.9 GB Report
EGAF00006219823 fastq.gz 3.8 GB Report
EGAF00006219824 fastq.gz 3.7 GB Report
EGAF00006219825 fastq.gz 6.0 GB Report
EGAF00006219826 fastq.gz 6.0 GB Report
EGAF00006219827 fastq.gz 6.3 GB Report
EGAF00006219828 fastq.gz 6.3 GB Report
EGAF00006219829 fastq.gz 7.3 GB Report
EGAF00006219830 fastq.gz 7.6 GB Report
EGAF00006219831 fastq.gz 2.9 GB Report
EGAF00006219832 fastq.gz 3.1 GB Report
EGAF00006219833 fastq.gz 4.9 GB Report
EGAF00006219834 fastq.gz 5.1 GB Report
EGAF00006219835 fastq.gz 4.5 GB Report
EGAF00006219836 fastq.gz 4.6 GB Report
EGAF00006219837 fastq.gz 4.8 GB Report
EGAF00006219838 fastq.gz 4.8 GB Report
EGAF00006219839 fastq.gz 2.8 GB Report
EGAF00006219840 fastq.gz 2.9 GB Report
EGAF00006219841 fastq.gz 3.1 GB Report
EGAF00006219842 fastq.gz 3.3 GB Report
EGAF00006219843 fastq.gz 3.2 GB Report
EGAF00006219844 fastq.gz 3.4 GB Report
EGAF00006219845 fastq.gz 4.1 GB Report
EGAF00006219846 fastq.gz 4.2 GB Report
EGAF00006219847 fastq.gz 3.7 GB Report
EGAF00006219848 fastq.gz 4.0 GB Report
EGAF00006219849 fastq.gz 4.1 GB Report
EGAF00006219850 fastq.gz 4.5 GB Report
EGAF00006219851 fastq.gz 3.2 GB Report
EGAF00006219852 fastq.gz 3.4 GB Report
EGAF00006219853 fastq.gz 5.2 GB Report
EGAF00006219854 fastq.gz 5.7 GB Report
EGAF00006219855 fastq.gz 4.3 GB Report
EGAF00006219856 fastq.gz 4.4 GB Report
EGAF00006219857 fastq.gz 7.5 GB Report
EGAF00006219858 fastq.gz 7.6 GB Report
EGAF00006219859 fastq.gz 4.5 GB Report
EGAF00006219860 fastq.gz 4.5 GB Report
EGAF00006219861 fastq.gz 2.7 GB Report
EGAF00006219862 fastq.gz 2.8 GB Report
EGAF00006219863 fastq.gz 3.2 GB Report
EGAF00006219864 fastq.gz 3.5 GB Report
EGAF00006219865 fastq.gz 3.0 GB Report
EGAF00006219866 fastq.gz 3.2 GB Report
EGAF00006219867 fastq.gz 7.1 GB Report
EGAF00006219868 fastq.gz 7.1 GB Report
EGAF00006219869 fastq.gz 4.7 GB Report
EGAF00006219870 fastq.gz 4.6 GB Report
EGAF00006219871 fastq.gz 3.6 GB Report
EGAF00006219872 fastq.gz 3.6 GB Report
EGAF00006219873 fastq.gz 3.6 GB Report
EGAF00006219874 fastq.gz 3.6 GB Report
EGAF00006219875 fastq.gz 3.9 GB Report
EGAF00006219876 fastq.gz 4.2 GB Report
EGAF00006219877 fastq.gz 3.4 GB Report
EGAF00006219878 fastq.gz 3.7 GB Report
EGAF00006219879 fastq.gz 3.7 GB Report
EGAF00006219880 fastq.gz 4.0 GB Report
EGAF00006219881 fastq.gz 2.8 GB Report
EGAF00006219882 fastq.gz 3.0 GB Report
EGAF00006219883 fastq.gz 2.3 GB Report
EGAF00006219884 fastq.gz 2.6 GB Report
EGAF00006219885 fastq.gz 4.2 GB Report
EGAF00006219886 fastq.gz 4.2 GB Report
EGAF00006219887 fastq.gz 3.6 GB Report
EGAF00006219888 fastq.gz 3.7 GB Report
EGAF00006219889 fastq.gz 4.0 GB Report
EGAF00006219890 fastq.gz 4.2 GB Report
EGAF00006219891 fastq.gz 8.4 GB Report
EGAF00006219892 fastq.gz 8.7 GB Report
EGAF00006219893 fastq.gz 4.1 GB Report
EGAF00006219894 fastq.gz 4.4 GB Report
EGAF00006219895 fastq.gz 3.5 GB Report
EGAF00006219896 fastq.gz 3.9 GB Report
EGAF00006219897 fastq.gz 3.0 GB Report
EGAF00006219898 fastq.gz 3.3 GB Report
EGAF00006219899 fastq.gz 4.5 GB Report
EGAF00006219900 fastq.gz 4.8 GB Report
EGAF00006219901 fastq.gz 5.4 GB Report
EGAF00006219902 fastq.gz 5.9 GB Report
EGAF00006219903 fastq.gz 3.1 GB Report
EGAF00006219904 fastq.gz 3.5 GB Report
EGAF00006219905 fastq.gz 5.8 GB Report
EGAF00006219906 fastq.gz 6.2 GB Report
EGAF00006219907 fastq.gz 5.8 GB Report
EGAF00006219908 fastq.gz 6.2 GB Report
EGAF00006219909 fastq.gz 3.8 GB Report
EGAF00006219910 fastq.gz 4.1 GB Report
EGAF00006219911 fastq.gz 6.6 GB Report
EGAF00006219912 fastq.gz 6.8 GB Report
EGAF00006219913 fastq.gz 3.8 GB Report
EGAF00006219914 fastq.gz 4.1 GB Report
EGAF00006219915 fastq.gz 7.0 GB Report
EGAF00006219916 fastq.gz 7.5 GB Report
EGAF00006219917 fastq.gz 4.7 GB Report
EGAF00006219918 fastq.gz 4.8 GB Report
EGAF00006219919 fastq.gz 4.9 GB Report
EGAF00006219920 fastq.gz 5.0 GB Report
EGAF00006219921 fastq.gz 5.8 GB Report
EGAF00006219922 fastq.gz 6.0 GB Report
EGAF00006219923 fastq.gz 4.9 GB Report
EGAF00006219924 fastq.gz 5.2 GB Report
EGAF00006219925 fastq.gz 5.1 GB Report
EGAF00006219926 fastq.gz 5.6 GB Report
EGAF00006219927 fastq.gz 4.1 GB Report
EGAF00006219928 fastq.gz 4.4 GB Report
EGAF00006219929 fastq.gz 3.6 GB Report
EGAF00006219930 fastq.gz 3.9 GB Report
EGAF00006219931 fastq.gz 3.3 GB Report
EGAF00006219932 fastq.gz 3.7 GB Report
EGAF00006219933 fastq.gz 3.4 GB Report
EGAF00006219934 fastq.gz 3.5 GB Report
EGAF00006219935 fastq.gz 6.6 GB Report
EGAF00006219936 fastq.gz 6.8 GB Report
EGAF00006219937 fastq.gz 3.9 GB Report
EGAF00006219938 fastq.gz 4.1 GB Report
EGAF00006219939 fastq.gz 4.9 GB Report
EGAF00006219940 fastq.gz 5.4 GB Report
EGAF00006219941 fastq.gz 4.6 GB Report
EGAF00006219942 fastq.gz 5.0 GB Report
EGAF00006219943 fastq.gz 3.6 GB Report
EGAF00006219944 fastq.gz 3.8 GB Report
EGAF00006219945 fastq.gz 4.5 GB Report
EGAF00006219946 fastq.gz 4.7 GB Report
EGAF00006219947 fastq.gz 4.0 GB Report
EGAF00006219948 fastq.gz 4.2 GB Report
EGAF00006219949 fastq.gz 4.2 GB Report
EGAF00006219950 fastq.gz 4.3 GB Report
EGAF00006219951 fastq.gz 3.3 GB Report
EGAF00006219952 fastq.gz 3.5 GB Report
236 Files (1.1 TB)