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Induction Failure in Childhood and Young Adult T-cell Acute Lymphoblastic Leukemia

We carried out WGS and RNAseq on a cohort of 48 children and young adults with induction failure in T-cell Acute Lymphoblastic Leukemia (T-ALL) to identify genomic drivers of treatment resistance. The study includes WGS for 33 tumour/normal pairs and 15 tumour-only samples. In addition, there is RNAseq data for 37 cases.

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The data within this dataset will be made available to researchers from recognised academic institutions that wish to perform further research on related topics. Please contact the DAC for further information.

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. 1. The User Institution agrees to only use these Data for the purpose of the Project for which the User Institution has requested access, and only for Research Purposes. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 5. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006411 Cancer Genomics
ID File Type Size Located in
EGAF00006457824 cram 2.6 GB
EGAF00006457825 cram 2.3 GB
EGAF00006457826 cram 2.5 GB
EGAF00006457827 cram 2.5 GB
EGAF00006457828 cram 1.8 GB
EGAF00006457829 cram 1.6 GB
EGAF00006457830 cram 4.0 GB
EGAF00006457831 cram 2.7 GB
EGAF00006457832 cram 1.8 GB
EGAF00006457833 cram 1.7 GB
EGAF00006457834 cram 1.8 GB
EGAF00006457835 cram 1.9 GB
EGAF00006457836 cram 2.3 GB
EGAF00006457837 cram 4.8 GB
EGAF00006457838 cram 2.5 GB
EGAF00006457839 cram 1.3 GB
EGAF00006457840 cram 3.6 GB
EGAF00006457841 cram 1.6 GB
EGAF00006457842 cram 1.6 GB
EGAF00006457843 cram 1.5 GB
EGAF00006457844 cram 1.5 GB
EGAF00006457845 cram 3.5 GB
EGAF00006457846 cram 2.7 GB
EGAF00006457847 cram 3.1 GB
EGAF00006457848 cram 3.6 GB
EGAF00006457849 cram 4.4 GB
EGAF00006457850 cram 4.3 GB
EGAF00006457851 cram 3.1 GB
EGAF00006457852 cram 3.3 GB
EGAF00006457853 cram 3.4 GB
EGAF00006457854 cram 3.7 GB
EGAF00006457855 cram 3.7 GB
EGAF00006457856 cram 4.6 GB
EGAF00006457857 cram 3.0 GB
EGAF00006457858 cram 4.1 GB
EGAF00006457859 cram 5.1 GB
EGAF00006457860 cram 3.2 GB
EGAF00006457861 cram 108.3 GB
EGAF00006457862 cram 216.7 GB
EGAF00006457863 cram 102.2 GB
EGAF00006457864 cram 216.9 GB
EGAF00006457865 cram 121.7 GB
EGAF00006457866 cram 208.1 GB
EGAF00006457867 cram 105.6 GB
EGAF00006457868 cram 209.3 GB
EGAF00006457869 cram 106.9 GB
EGAF00006457870 cram 221.7 GB
EGAF00006457871 cram 101.5 GB
EGAF00006457872 cram 202.5 GB
EGAF00006457873 cram 120.0 GB
EGAF00006457874 cram 221.7 GB
EGAF00006457875 cram 59.4 GB
EGAF00006457876 cram 30.3 GB
EGAF00006457877 cram 52.0 GB
EGAF00006457878 cram 32.0 GB
EGAF00006457879 cram 50.5 GB
EGAF00006457880 cram 32.2 GB
EGAF00006457881 cram 52.3 GB
EGAF00006457882 cram 34.7 GB
EGAF00006457883 cram 65.1 GB
EGAF00006457884 cram 68.9 GB
EGAF00006457885 cram 50.8 GB
EGAF00006457886 cram 58.7 GB
EGAF00006457887 cram 56.6 GB
EGAF00006457888 cram 78.9 GB
EGAF00006457889 cram 61.1 GB
EGAF00006457890 cram 73.5 GB
EGAF00006457891 cram 30.7 GB
EGAF00006457892 cram 45.4 GB
EGAF00006457893 cram 41.0 GB
EGAF00006457894 cram 47.5 GB
EGAF00006457895 cram 39.8 GB
EGAF00006457896 cram 69.8 GB
EGAF00006457897 cram 62.0 GB
EGAF00006457898 cram 52.4 GB
EGAF00006457899 cram 54.8 GB
EGAF00006457900 cram 48.2 GB
EGAF00006457901 cram 38.3 GB
EGAF00006457902 cram 58.7 GB
EGAF00006457903 cram 54.2 GB
EGAF00006457904 cram 71.5 GB
EGAF00006457905 cram 69.5 GB
EGAF00006457906 cram 60.7 GB
EGAF00006457907 cram 48.2 GB
EGAF00006457908 cram 33.2 GB
EGAF00006457909 cram 32.4 GB
EGAF00006457910 cram 32.3 GB
EGAF00006457911 cram 37.3 GB
EGAF00006457912 cram 37.0 GB
EGAF00006457913 cram 40.5 GB
EGAF00006457914 cram 53.8 GB
EGAF00006457915 cram 27.3 GB
EGAF00006457916 cram 52.5 GB
EGAF00006457917 cram 64.3 GB
EGAF00006457918 cram 62.7 GB
EGAF00006457919 cram 49.4 GB
EGAF00006457920 cram 53.0 GB
EGAF00006457921 cram 67.1 GB
EGAF00006457922 cram 49.5 GB
EGAF00006457923 cram 50.5 GB
EGAF00006457924 cram 53.2 GB
EGAF00006457925 cram 49.8 GB
EGAF00006457926 cram 57.7 GB
EGAF00006457927 cram 45.6 GB
EGAF00006457928 cram 55.4 GB
EGAF00006457929 cram 58.4 GB
EGAF00006457930 cram 61.8 GB
EGAF00006457931 cram 27.8 GB
EGAF00006457932 cram 31.5 GB
EGAF00006457933 cram 35.2 GB
EGAF00006457934 cram 36.9 GB
EGAF00006457935 cram 34.5 GB
EGAF00006457936 cram 35.2 GB
EGAF00006457937 cram 34.8 GB
EGAF00006457938 cram 29.0 GB
EGAF00006457939 cram 36.9 GB
EGAF00006457940 cram 52.4 GB
EGAF00006457941 cram 53.5 GB
118 Files (5.7 TB)