ATAC-seq in hiPSC-derived neurons after BDNF and KCl stimulations

DAC for Chromatin accessibility changes in hiPSC-derived neurons after BDNF and KCl stimulations

## Data Controller Institution’s Legal Name: European Molecular Biology Laboratory (EMBL) Institutional Postal Address: Meyerhofstraße 1, 69117 Heidelberg Institutional E-mail Address: coo-office@embl.org Website of the Institution: https://www.embl.org/ ## Authorised Representative of the Data Controller Name: Matti Tiirakari Position: Chief Operating Officer Affiliation: European Molecular Biology Laboratory (EMBL) Institutional Postal Address: Meyerhofstraße 1, 69117 Heidelberg Institutional E-mail Address: coo-office@embl.org Definitions Data: Refers to the controlled access data (the Data). Under this Agreement, the Data is pseudonymised. Data Access/Transfer: Refers to an Institution’s right to request access to the Data and retrieve them from the Data Controller’s Institution upon approval of this DAA by the corresponding DAC within the Data Controller’s Institution. Data Handling: Refers to an Institution’s ability to analyse and manipulate the Data within its own computer network. Data Controller: Refers to the European Molecular Biology Laboratory, which is responsible for the generation of the Data and its pseudonymisation. Data Subject: Refers to any individual who is the source of any Data covered by this Agreement. Data Protection Legislation: Refers, in respect of EMBL, to its Internal Policy No. 68 on General Data Protection, while, in respect of the Data Recipient, to Regulation (EU) 2016/679 of the European Parliament and of the Council (GDPR) and/or any other applicable national data protection legislation. Data Recipient (‘You’): Refers to the Institution who requests Access to the Data through this Agreement. Authorised Personnel: The individual(s) at the Institution requesting Access to the Data. Research Project: The Project for which You have requested Access to the Data. Publications: Refers, without limitation, to any and all articles published in print journals, electronic journals, reviews, books, posters, and other written and verbal presentations of Research that have been accepted by peer review. Terms and Conditions 1. You, the Data Recipient, agree to only use the Data for the Purpose of the Project. 2. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. You undertake not to use or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 3. You agree not to attempt to identify Data Subjects. 4. You and your Authorised Personnel agree to take into consideration any usage restrictions (if any), stemming from consent, i.e. the appropriate lawful basis for processing the Data, as well as any usage restrictions stemming from any applicable internal policies of your Institution. 5. You agree that in handling this Data You will follow an up-to-date information technology (IT) policy that must include, at a minimum, the following items: a. Logging and auditing of Access to the Data and to the computer network; b. Password protection to computer network and/or strong data encryption; c. Virus and malware protection to computers on the computer network; d. Secure backup procedure; 6. You acknowledge that Access to the Data is granted for the duration of the Project described in Section I, as well as any new Project under the same research field or area. Any use of the Data for a Project of another research field or area will need to be approved under a new Agreement. 7. You recognize that nothing in this Agreement shall operate to transfer to You any intellectual property rights to the Data. 8. You agree not to make intellectual property claims on the Data and not to use intellectual property protection in ways that would prevent or block Access to, or use of, any element of the Data. 9. You can elect to perform further Research that would add intellectual and resource capital to the Data, and decide to obtain intellectual property rights on these downstream discoveries. In this case, You agree to implement licensing policies that will not obstruct further Research, following the Organisation for Economic Co-operation and Development Guidelines. 10. You agree that the Research Project 1) bears no legal responsibility for the accuracy or comprehensiveness of the Data; 2) accepts no liability for indirect, consequential, or incidental damages or losses arising from use of the Data; and 3) bears no responsibility for the further analysis or interpretation of these Data over and above that published by the Controller(s). 11. You agree to hold the Data Subject(s) and Data Controller(s) harmless and to defend and indemnify all these parties against all liabilities, demands, damages, expenses, and losses arising out of Your use for any Purpose of the Data. 12. You agree to a moratorium on publishing global analyses of the dataset until the Data Controller(s) have published their own global analysis or twelve (12) months, the maximum, have passed from the time the Data were deposited, whichever occurs first. You acknowledge that prompt publication or public disclosure of the results of the Research Project is encouraged. You also agree that by publishing Your global analyses of the Data, you will not disclose any results generated from the Data. 13. You agree to acknowledge the contribution of the Data Controller(s) in all oral and written presentations, disclosures, and Publications resulting from all analyses of the Data. 14. You agree to use the Data in Your laboratory. Any Authorised Personnel shall work under Your direct supervision. You agree to distribute a copy of these terms to the Authorised Personnel. 15. You may not transfer any information included in the Data to anyone unless specifically designated in the Research Project, or by prior specific or general written authorisation of the Data Controller(s) responsible for the generation of the original Data in each case. 16. You may not transfer the Data itself to anyone outside the Institution, unless the Controller(s) has (have) approved such transfer and its terms in writing. 17. Should You wish to share the Data with an external collaborator, the external collaborator must complete a separate Data Access Agreement. 18. You shall ensure that ‘all’ who have Access to the Data, namely You and Your Authorised Personnel, will be listed out, and are made aware and be bound by the terms of this Agreement. You remain solely and fully responsible for Your Authorised Personnel’s non-compliance with the provision of the Agreement and/or applicable laws. 19. In case of a breach of security resulting from ‘accidental’ use of Data by You and Your Authorised Personnel, which leads to disclosure of Data, then You must report this to Data Controller(s) within 72 hours maximum, and follow any relevant rule as provided by the applicable Data Protection Legislation. 20. In case of a ‘non-accidental or minor’ breach of this DAA by You, You will further be required to destroy any Data held. 21. You accept that this Agreement will terminate immediately upon ‘any’ breach by You, or its termination (see Section I). 22. You endeavour to settle any dispute with the Data Controller(s) amicably. If you are unable to reach an Agreement, you will meet and negotiate in good faith in an effort to resolve the issue. If the issue has not been resolved within a reasonable period (e.g. 30 calendar days), you are both entitled to submit it for resolution by an arbitration, in accordance with the following clauses. 23. The provisions of this Agreement shall be interpreted in accordance with their true meaning and effect. Without prejudice to the Data Controller’s status as an intergovernmental institution, reference shall be made to the substantive law of the Federal Republic of Germany, where: (a) A matter is not specifically covered by the agreement; or (b) A provision is ambiguous or unclear. Such reference shall be made exclusively for the matter or provision(s) concerned, and shall in no event apply to the other provisions of the agreement. In any event, nothing in this Agreement nor any document or activity under or in relation thereto shall be deemed or interpreted as a waiver, express or implied, of any privileges or immunities accorded to the Data Controller by its constituent documents or international law, or as the acceptance by the Data Controller of the jurisdiction of (i) the courts of any country, including in case of injunctive relief sought, or (ii) any national regulatory authority. All references to specific regulations, including, but not limited to, national laws, policies, ordinances, statutes, guidelines, ethics rules and regulations, codes of conduct and other rules and regulations, should only be understood as a reference, with regard to the Data Controller, to the extent that these regulations also apply to the Data Controller as an intergovernmental body and, in cases where the Data Controller has issued its own rules, as a reference to these rules instead. The rules of private international law and the United Nations Convention on Contracts for the International Sale of Goods shall not apply. 24. All disputes arising out of or in connection with this contract or its validity that cannot be resolved amicably by the parties shall be finally settled in accordance with the Arbitration Rules of the German Arbitration Institute (DIS) without recourse to the ordinary courts of law, including for injunctive relief. The award of the arbitration will be final and binding upon the parties concerned. The arbitral tribunal shall be comprised of three members. The seat of the arbitration shall be Heidelberg. The language of the arbitration shall be English.