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Single nuclei RNA-Seq from 5 regions of the human fetal brain

Data generated through single nuclei RNA sequencing on 5 regions of the brain (frontal cortex, ganglionic eminence, hippocampus, thalamus and cerebellum) from 3 fetuses (two of 14 and one of 15 post-conception weeks, all female). Tissue was acquired from the MRC-Wellcome Trust Human Developmental Biology Resource (HDBR) with ethical approval. snRNA-seq libraries were prepared from ∼10,000 nuclei from each sample using Chromium Single Cell 3ʹ (v3) reagents (10X Genomics). Quality control of libraries was performed using the Agilent 5200 Fragment Analyzer before sequencing on an Illumina NovaSeq 6000 to a depth of at least 865 million (median = 1.01 billion) read pairs per library. Raw sequencing data were converted into FASTQ files. For a full description of data generation, please see Cameron et al, Biological Psychiatry 2022, https://doi.org/10.1016/j.biopsych.2022.06.033.

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Access to data is available through application to the Cardiff University DPMCN Functional Genomics Data Access Committee (email: BrayN3@Cardiff.ac.uk).

Access to data is available through application to the Cardiff University DPMCN Functional Genomics Data Access Committee (email: BrayN3@Cardiff.ac.uk). Data access will be granted to Principal Investigators with an institutional affiliation, and where the proposed research is consistent with the data use limitations of the dataset (based on original informed consent from the donors). 

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006537 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006895731 fastq.gz 5.4 GB
EGAF00006895732 fastq.gz 12.3 GB
EGAF00006895733 fastq.gz 5.5 GB
EGAF00006895734 fastq.gz 12.5 GB
EGAF00006895735 fastq.gz 5.5 GB
EGAF00006895736 fastq.gz 12.5 GB
EGAF00006895737 fastq.gz 5.4 GB
EGAF00006895738 fastq.gz 12.4 GB
EGAF00006895739 fastq.gz 6.1 GB
EGAF00006895740 fastq.gz 13.0 GB
EGAF00006895741 fastq.gz 6.2 GB
EGAF00006895742 fastq.gz 13.3 GB
EGAF00006895743 fastq.gz 6.6 GB
EGAF00006895744 fastq.gz 14.0 GB
EGAF00006895745 fastq.gz 6.4 GB
EGAF00006895746 fastq.gz 13.7 GB
EGAF00006895747 fastq.gz 5.4 GB
EGAF00006895748 fastq.gz 12.2 GB
EGAF00006895749 fastq.gz 5.6 GB
EGAF00006895750 fastq.gz 12.5 GB
EGAF00006895751 fastq.gz 5.8 GB
EGAF00006895752 fastq.gz 13.0 GB
EGAF00006895753 fastq.gz 5.7 GB
EGAF00006895754 fastq.gz 12.8 GB
EGAF00006895755 fastq.gz 5.4 GB
EGAF00006895756 fastq.gz 12.3 GB
EGAF00006895757 fastq.gz 5.5 GB
EGAF00006895758 fastq.gz 12.5 GB
EGAF00006895759 fastq.gz 5.5 GB
EGAF00006895760 fastq.gz 12.5 GB
EGAF00006895761 fastq.gz 5.5 GB
EGAF00006895762 fastq.gz 12.4 GB
EGAF00006895763 fastq.gz 5.8 GB
EGAF00006895764 fastq.gz 12.8 GB
EGAF00006895765 fastq.gz 5.9 GB
EGAF00006895766 fastq.gz 13.0 GB
EGAF00006895767 fastq.gz 6.1 GB
EGAF00006895768 fastq.gz 13.5 GB
EGAF00006895769 fastq.gz 6.0 GB
EGAF00006895770 fastq.gz 13.2 GB
EGAF00006895771 fastq.gz 6.9 GB
EGAF00006895772 fastq.gz 15.8 GB
EGAF00006895773 fastq.gz 7.0 GB
EGAF00006895774 fastq.gz 16.1 GB
EGAF00006895775 fastq.gz 7.1 GB
EGAF00006895776 fastq.gz 16.2 GB
EGAF00006895777 fastq.gz 7.0 GB
EGAF00006895778 fastq.gz 16.0 GB
EGAF00006895779 fastq.gz 6.7 GB
EGAF00006895780 fastq.gz 15.5 GB
EGAF00006895781 fastq.gz 6.8 GB
EGAF00006895782 fastq.gz 15.8 GB
EGAF00006895783 fastq.gz 6.9 GB
EGAF00006895784 fastq.gz 15.8 GB
EGAF00006895785 fastq.gz 6.8 GB
EGAF00006895786 fastq.gz 15.7 GB
EGAF00006895787 fastq.gz 4.9 GB
EGAF00006895788 fastq.gz 11.1 GB
EGAF00006895789 fastq.gz 5.2 GB
EGAF00006895790 fastq.gz 11.6 GB
EGAF00006895791 fastq.gz 5.5 GB
EGAF00006895792 fastq.gz 12.2 GB
EGAF00006895793 fastq.gz 5.4 GB
EGAF00006895794 fastq.gz 12.0 GB
EGAF00006895795 fastq.gz 5.4 GB
EGAF00006895796 fastq.gz 12.2 GB
EGAF00006895797 fastq.gz 5.6 GB
EGAF00006895798 fastq.gz 12.5 GB
EGAF00006895799 fastq.gz 5.8 GB
EGAF00006895800 fastq.gz 13.0 GB
EGAF00006895801 fastq.gz 5.7 GB
EGAF00006895802 fastq.gz 12.8 GB
EGAF00006895803 fastq.gz 5.3 GB
EGAF00006895804 fastq.gz 12.1 GB
EGAF00006895805 fastq.gz 5.4 GB
EGAF00006895806 fastq.gz 12.3 GB
EGAF00006895807 fastq.gz 5.4 GB
EGAF00006895808 fastq.gz 12.3 GB
EGAF00006895809 fastq.gz 5.3 GB
EGAF00006895810 fastq.gz 12.2 GB
EGAF00006895811 fastq.gz 4.8 GB
EGAF00006895812 fastq.gz 10.9 GB
EGAF00006895813 fastq.gz 4.8 GB
EGAF00006895814 fastq.gz 11.1 GB
EGAF00006895815 fastq.gz 4.9 GB
EGAF00006895816 fastq.gz 11.1 GB
EGAF00006895817 fastq.gz 4.8 GB
EGAF00006895818 fastq.gz 11.0 GB
EGAF00006895819 fastq.gz 5.3 GB
EGAF00006895820 fastq.gz 11.7 GB
EGAF00006895821 fastq.gz 5.4 GB
EGAF00006895822 fastq.gz 12.0 GB
EGAF00006895823 fastq.gz 5.6 GB
EGAF00006895824 fastq.gz 12.4 GB
EGAF00006895825 fastq.gz 5.5 GB
EGAF00006895826 fastq.gz 12.2 GB
EGAF00006895827 fastq.gz 6.7 GB
EGAF00006895828 fastq.gz 15.4 GB
EGAF00006895829 fastq.gz 6.8 GB
EGAF00006895830 fastq.gz 15.7 GB
EGAF00006895831 fastq.gz 6.8 GB
EGAF00006895832 fastq.gz 15.6 GB
EGAF00006895833 fastq.gz 6.8 GB
EGAF00006895834 fastq.gz 15.5 GB
EGAF00006895835 fastq.gz 6.6 GB
EGAF00006895836 fastq.gz 15.0 GB
EGAF00006895837 fastq.gz 6.7 GB
EGAF00006895838 fastq.gz 15.3 GB
EGAF00006895839 fastq.gz 6.7 GB
EGAF00006895840 fastq.gz 15.3 GB
EGAF00006895841 fastq.gz 6.7 GB
EGAF00006895842 fastq.gz 15.2 GB
EGAF00006895843 fastq.gz 4.5 GB
EGAF00006895844 fastq.gz 10.3 GB
EGAF00006895845 fastq.gz 4.6 GB
EGAF00006895846 fastq.gz 10.5 GB
EGAF00006895847 fastq.gz 4.6 GB
EGAF00006895848 fastq.gz 10.5 GB
EGAF00006895849 fastq.gz 4.6 GB
EGAF00006895850 fastq.gz 10.4 GB
EGAF00006895851 fastq.gz 5.2 GB
EGAF00006895852 fastq.gz 12.0 GB
EGAF00006895853 fastq.gz 5.3 GB
EGAF00006895854 fastq.gz 12.2 GB
EGAF00006895855 fastq.gz 5.3 GB
EGAF00006895856 fastq.gz 12.2 GB
EGAF00006895857 fastq.gz 5.3 GB
EGAF00006895858 fastq.gz 12.1 GB
EGAF00006895859 fastq.gz 5.0 GB
EGAF00006895860 fastq.gz 11.4 GB
EGAF00006895861 fastq.gz 5.1 GB
EGAF00006895862 fastq.gz 11.6 GB
EGAF00006895863 fastq.gz 5.1 GB
EGAF00006895864 fastq.gz 11.6 GB
EGAF00006895865 fastq.gz 5.0 GB
EGAF00006895866 fastq.gz 11.5 GB
136 Files (1.3 TB)