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Baseline and progression dataset

RNAseq FASTq files from 44 pre-treatment (Ven-Obi or Clb-Obi) and 44 paired, post-treatment relapsed CD19+ B cells.

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Genentech Data Access Agreement for Academic Institutions

GENENTECH DATA ACCESS COMMITTEE DATA ACCESS AGREEMENT This Data Access Agreement (“Agreement”) between Genentech, Inc. (“Genentech”) and User andUser Institution (as defined below) governs the terms on which access will be granted to thegenotype data obtained from Genentech. In signing this Agreement, User and User Institution agree to be bound by the terms and conditions of access set out in this Agreement. For the sake of clarity, the terms of access set out in this Agreement shall govern activities conducted by the User and the User Institution (as defined below). User Institution and User are referred to within the Agreement as “You” and “Your” for convenience only. Definitions: gRED means Genentech Research and Early Development. Data means all and any human genetic data generated by gRED and requested by User through submission of an Application for Access to Genotype Data and obtained from Genentech under the terms of this Agreement. Data Subject means a person, who has been informed of the purpose for which the Data is held and has given his/her informed consent thereto. User means a researcher who has requested Data by submitting an Application for Access to Genotype Data to gRED and whose User Institution has previously completed this Data Access Agreement with respect to such Data and has received acknowledgement of its acceptance. Publications means, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User Institution means the organization at which the User is employed, affiliated or enrolled. Genentech Data Access Committee means members of the gRED organization that are responsible for making the data access decisions for the genotype data generated by gRED. Terms and Conditions: In signing this Agreement: 1. You agree to use the Data only for the advancement of medical research. 2. You agree not to use the data for the creation of products for sale or for any commercial purpose. 3. You agree to preserve, at all times, the confidentiality of Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy.DSC: Academic Data Access Agreement vMar2021 1 4. You agree not to attempt to link the Data provided under this Agreement to any other data source on the same samples or to link the Data to any person or otherwise identify any Data Subject from the Data. 5. You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others, except as necessary for data/safety monitoring or programmanagement. Should You wish to share the Data with a collaborator outside the same Institution, the third party must make a separate application for access to the Data. 6. You agree to use the Data for the approved purpose and project described in your Application for Access to Raw Exome Sequencing and/or RNA Sequencing Data; use of the Data for a new purpose or project will require a new application and approval. You agree to restrict your use of the Data to the analysis of somatic mutations and/or gene expression level only; use of these data to infer genotype is not permitted. 7. You agree that publication of Your purpose, project, and results is restricted for a one (1) year period starting from the publication date of the Genentech publication referencing the Data deposit. You will be free to publish the results of the research using the Data for the approved purpose after the one (1) year period has expired. You will not publish the Data, but will refer to the original Data deposit by Genentech and agree to acknowledge in any such publication that the research makes use of Data generated by Genentech. 8. You accept that Genentech: (a) bears no legal responsibility for the accuracy or comprehensiveness of the Data; and (b) accepts no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason. 9. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted. 10. You recognize that nothing in this Agreement shall operate to transfer to the User Institution any intellectual property rights relating to the Data. 11. You agree that You will submit a report to the Genentech Data Access Committee, if requested, on completion of the approved purpose. The Genentech Data Access Committee agrees to treat the report and all information, data, results, and conclusions contained within such report as confidential information belonging to the User Institution. 12. (a) You agree to use the Data in accordance with all applicable laws, including but not limited to applicable data privacy laws. (b)The Genentech Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures. 13. This Agreement shall be effective as of the date of the last party to sign below (“Effective Date”) and shall terminate three (3) years after the Effective Date, unless terminated sooner pursuant to Section 14 below. Upon termination, You will be required to destroy any Data held. 14. You accept that this Agreement will terminate immediately upon any breach of this Agreement by You. Either party may terminate this Agreement upon thirty (30) days written notice for any reason. The following Sections of this Agreement shall survive its expiration or termination:DSC: Academic Data Access Agreement vMar2021 2 Sections 1 – 10, 12(a), and 14-17 15. Nothing herein shall create any association, partnership, joint venture, fiduciary duty or the relation of principal and agent between the parties hereto, it being understood that each party is acting as an independent contractor, and neither party shall have the authority to bind the other or the other’s representatives in any way. 16. Except as required by law or permitted under Section 7, neither party shall use or refer to this Agreement in the public media, or use the names or marks of the other party without express prior written permission. 17. This Agreement may be executed by the parties hereto in separate counterparts, each of which when so executed and delivered shall be deemed an original, but all such counterparts shall together constitute one and the same agreement. The parties agree that execution of this Agreement by exchanging facsimile, PDF, or e-Signature (as defined below) signatures shall have the same legal force and effect as the exchange of original signatures. Pursuant to this Agreement, e-Signatures shall mean a signature that consists of one or more letters, characters, numbers or other symbols in digital form incorporated in, attached to or associated with the electronic document, that (a) is unique to the person making the signature; (b) the technology or process used to make the signature is under the sole control of the person making the signature; (b) the technology or process can be used to identify the person using the technology or process; and (d) the electronic signature can be linked with an electronic document in such a way that it can be used to determine whether the electronic document has been changed since the electronic signature was incorporated in, attached to or associated with the electronic document. The written form shall be required to make changes to this clause as well. IN WITNESS WHEREOF, the parties have caused this Agreement to be executed by their respective duly authorized representatives as set forth below. Genentech, Inc. For and on behalf of User Institution: (Institutional or Administrative Authority) Signature: Signature: Print Name: Print Name: Title: Title: Date: Date: Read and acknowledged by User/Applicant: Signature: Print Name: Title: Date:DSC: Academic Data Access Agreement vMar2021 3

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006596 Other
ID File Type Size Located in
EGAF00007133940 fastq.gz 3.7 GB
EGAF00007133941 fastq.gz 3.7 GB
EGAF00007133942 fastq.gz 3.1 GB
EGAF00007133943 fastq.gz 3.2 GB
EGAF00007133944 fastq.gz 2.3 GB
EGAF00007133945 fastq.gz 2.4 GB
EGAF00007133946 fastq.gz 3.3 GB
EGAF00007133947 fastq.gz 3.4 GB
EGAF00007133948 fastq.gz 2.4 GB
EGAF00007133949 fastq.gz 2.4 GB
EGAF00007133954 fastq.gz 2.2 GB
EGAF00007133955 fastq.gz 2.1 GB
EGAF00007133968 fastq.gz 1.9 GB
EGAF00007133969 fastq.gz 1.9 GB
EGAF00007133974 fastq.gz 1.8 GB
EGAF00007133975 fastq.gz 1.9 GB
EGAF00007133990 fastq.gz 2.3 GB
EGAF00007133991 fastq.gz 2.3 GB
EGAF00007134002 fastq.gz 1.8 GB
EGAF00007134003 fastq.gz 1.9 GB
EGAF00007134008 fastq.gz 2.0 GB
EGAF00007134009 fastq.gz 2.0 GB
EGAF00007134024 fastq.gz 1.6 GB
EGAF00007134025 fastq.gz 1.7 GB
EGAF00007134028 fastq.gz 1.9 GB
EGAF00007134029 fastq.gz 1.9 GB
EGAF00007134048 fastq.gz 1.9 GB
EGAF00007134049 fastq.gz 1.9 GB
EGAF00007134060 fastq.gz 1.7 GB
EGAF00007134061 fastq.gz 1.7 GB
EGAF00007134070 fastq.gz 2.4 GB
EGAF00007134071 fastq.gz 2.5 GB
EGAF00007134078 fastq.gz 2.5 GB
EGAF00007134079 fastq.gz 2.6 GB
EGAF00007134080 fastq.gz 1.4 GB
EGAF00007134081 fastq.gz 1.5 GB
EGAF00007134082 fastq.gz 1.6 GB
EGAF00007134083 fastq.gz 1.7 GB
EGAF00007134088 fastq.gz 2.7 GB
EGAF00007134089 fastq.gz 2.7 GB
EGAF00007134096 fastq.gz 2.9 GB
EGAF00007134097 fastq.gz 3.0 GB
EGAF00007134114 fastq.gz 1.8 GB
EGAF00007134115 fastq.gz 1.8 GB
EGAF00007134126 fastq.gz 1.6 GB
EGAF00007134127 fastq.gz 1.7 GB
EGAF00007134128 fastq.gz 1.8 GB
EGAF00007134129 fastq.gz 1.9 GB
EGAF00007134134 fastq.gz 2.8 GB
EGAF00007134135 fastq.gz 2.8 GB
EGAF00007134146 fastq.gz 1.9 GB
EGAF00007134147 fastq.gz 1.9 GB
EGAF00007134188 fastq.gz 1.8 GB
EGAF00007134189 fastq.gz 1.9 GB
EGAF00007134200 fastq.gz 1.9 GB
EGAF00007134201 fastq.gz 1.9 GB
EGAF00007134208 fastq.gz 2.9 GB
EGAF00007134209 fastq.gz 2.9 GB
EGAF00007134236 fastq.gz 1.6 GB
EGAF00007134237 fastq.gz 1.7 GB
EGAF00007134246 fastq.gz 2.8 GB
EGAF00007134247 fastq.gz 2.8 GB
EGAF00007134254 fastq.gz 2.7 GB
EGAF00007134255 fastq.gz 2.8 GB
EGAF00007134256 fastq.gz 1.8 GB
EGAF00007134257 fastq.gz 1.9 GB
EGAF00007134266 fastq.gz 1.6 GB
EGAF00007134267 fastq.gz 1.7 GB
EGAF00007134314 fastq.gz 2.7 GB
EGAF00007134315 fastq.gz 2.7 GB
EGAF00007134336 fastq.gz 1.9 GB
EGAF00007134337 fastq.gz 2.0 GB
EGAF00007134348 fastq.gz 2.5 GB
EGAF00007134349 fastq.gz 2.6 GB
EGAF00007134352 fastq.gz 2.5 GB
EGAF00007134353 fastq.gz 2.5 GB
EGAF00007134354 fastq.gz 1.8 GB
EGAF00007134355 fastq.gz 1.9 GB
EGAF00007134356 fastq.gz 1.6 GB
EGAF00007134357 fastq.gz 1.7 GB
EGAF00007134368 fastq.gz 1.7 GB
EGAF00007134369 fastq.gz 1.8 GB
EGAF00007134372 fastq.gz 2.7 GB
EGAF00007134373 fastq.gz 2.7 GB
EGAF00007134390 fastq.gz 2.2 GB
EGAF00007134391 fastq.gz 2.4 GB
EGAF00007134426 fastq.gz 3.6 GB
EGAF00007134427 fastq.gz 3.8 GB
EGAF00007134436 fastq.gz 2.8 GB
EGAF00007134437 fastq.gz 2.9 GB
EGAF00007134450 fastq.gz 1.6 GB
EGAF00007134451 fastq.gz 1.7 GB
EGAF00007134466 fastq.gz 1.8 GB
EGAF00007134467 fastq.gz 1.8 GB
EGAF00007134474 fastq.gz 1.9 GB
EGAF00007134475 fastq.gz 1.9 GB
EGAF00007134480 fastq.gz 3.0 GB
EGAF00007134481 fastq.gz 3.1 GB
EGAF00007134482 fastq.gz 3.0 GB
EGAF00007134483 fastq.gz 3.0 GB
EGAF00007134484 fastq.gz 2.5 GB
EGAF00007134485 fastq.gz 2.6 GB
EGAF00007134494 fastq.gz 2.7 GB
EGAF00007134495 fastq.gz 2.7 GB
EGAF00007134496 fastq.gz 1.8 GB
EGAF00007134497 fastq.gz 1.8 GB
EGAF00007134500 fastq.gz 1.8 GB
EGAF00007134501 fastq.gz 1.9 GB
EGAF00007134502 fastq.gz 2.1 GB
EGAF00007134503 fastq.gz 2.2 GB
EGAF00007134516 fastq.gz 2.7 GB
EGAF00007134517 fastq.gz 2.7 GB
EGAF00007134536 fastq.gz 2.6 GB
EGAF00007134537 fastq.gz 2.8 GB
EGAF00007134538 fastq.gz 2.6 GB
EGAF00007134539 fastq.gz 2.7 GB
EGAF00007134542 fastq.gz 1.7 GB
EGAF00007134543 fastq.gz 1.8 GB
EGAF00007134544 fastq.gz 1.7 GB
EGAF00007134545 fastq.gz 1.7 GB
EGAF00007134556 fastq.gz 3.0 GB
EGAF00007134557 fastq.gz 3.0 GB
EGAF00007134566 fastq.gz 2.5 GB
EGAF00007134567 fastq.gz 2.6 GB
EGAF00007134568 fastq.gz 1.7 GB
EGAF00007134569 fastq.gz 1.8 GB
EGAF00007134576 fastq.gz 1.7 GB
EGAF00007134577 fastq.gz 1.8 GB
EGAF00007134608 fastq.gz 1.7 GB
EGAF00007134609 fastq.gz 1.8 GB
EGAF00007134614 fastq.gz 2.7 GB
EGAF00007134615 fastq.gz 2.8 GB
EGAF00007134618 fastq.gz 2.7 GB
EGAF00007134619 fastq.gz 2.8 GB
EGAF00007134632 fastq.gz 1.9 GB
EGAF00007134633 fastq.gz 1.9 GB
EGAF00007134646 fastq.gz 2.6 GB
EGAF00007134647 fastq.gz 2.6 GB
EGAF00007134654 fastq.gz 1.7 GB
EGAF00007134655 fastq.gz 1.8 GB
EGAF00007134666 fastq.gz 1.9 GB
EGAF00007134667 fastq.gz 2.0 GB
EGAF00007134694 fastq.gz 2.6 GB
EGAF00007134695 fastq.gz 2.7 GB
EGAF00007134708 fastq.gz 2.6 GB
EGAF00007134709 fastq.gz 2.7 GB
EGAF00007134716 fastq.gz 1.7 GB
EGAF00007134717 fastq.gz 1.7 GB
EGAF00007134734 fastq.gz 1.9 GB
EGAF00007134735 fastq.gz 1.9 GB
EGAF00007134738 fastq.gz 2.0 GB
EGAF00007134739 fastq.gz 2.0 GB
EGAF00007134742 fastq.gz 1.9 GB
EGAF00007134743 fastq.gz 2.0 GB
EGAF00007134752 fastq.gz 1.9 GB
EGAF00007134753 fastq.gz 1.9 GB
EGAF00007134758 fastq.gz 2.5 GB
EGAF00007134759 fastq.gz 2.5 GB
EGAF00007134762 fastq.gz 2.4 GB
EGAF00007134763 fastq.gz 2.5 GB
EGAF00007134772 fastq.gz 2.0 GB
EGAF00007134773 fastq.gz 2.0 GB
EGAF00007134776 fastq.gz 1.8 GB
EGAF00007134777 fastq.gz 1.9 GB
EGAF00007134800 fastq.gz 1.6 GB
EGAF00007134801 fastq.gz 1.7 GB
EGAF00007134806 fastq.gz 1.8 GB
EGAF00007134807 fastq.gz 1.8 GB
EGAF00007134820 fastq.gz 2.9 GB
EGAF00007134821 fastq.gz 2.9 GB
EGAF00007134832 fastq.gz 2.8 GB
EGAF00007134833 fastq.gz 2.9 GB
EGAF00007134842 fastq.gz 1.9 GB
EGAF00007134843 fastq.gz 1.9 GB
EGAF00007134862 fastq.gz 2.6 GB
EGAF00007134863 fastq.gz 2.7 GB
176 Files (395.3 GB)