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Paired RNA-Seq of 32 samples of chemo-naïve and post-chemotherapy PDAC tumors

Paired RNA-Seq of 32 samples of chemo-naïve and post-chemotherapy PDAC tumors (HIPO_015) to define the molecular and cellular impact of neoadjuvant chemotherapy. Transcriptome analysis combined with high resolution mapping of whole tissue sections identified GATA6 (Classical), KRT17 (Basal-like) and Cytochrome P450 3A (CYP3A) co-expressing cells that were preferentially enriched in post-CTX resected samples. The sequencing was done on HiSeq2000/HiSeq2500 using the Takara_SMARTer_Ultra_Low_Input_RNA_and_NEBNext_ChIP-Seq Kit.

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Data Transfer Agreement for the German Cancer Research Center

To request access to the dataset please start a Data Access Request via the EGA DAC Portal. You will receive a HIPO DACO Info Form by email to collect information about the request, which has to be filled completely and signed by your PI. Your request will be evaluated by the responsible Data Access Committee (DAC) and our Data protection department (and innovation management if required). As soon as a positive decision is made, you will be provided with a data transfer agreement (DTA). After the DTA has been fully signed, access to the requested data is granted. To ensure that the process can be completed as quickly as possible, please note the following points: 1. The request in the EGA portal must be made by the responsible PI. 2. The information in the EGA portal must match the information on the HIPO DACO Info Form. In particular, the email address and the requested data sets must match. It is also important that all requested data sets are also listed on the HIPO DACO Info Form. For-profit companies are charged a fee per request.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007143 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00008025603 fastq.gz 4.9 GB
EGAF00008025604 fastq.gz 5.1 GB
EGAF00008025605 fastq.gz 3.3 GB
EGAF00008025606 fastq.gz 3.5 GB
EGAF00008025607 fastq.gz 3.2 GB
EGAF00008025608 fastq.gz 3.4 GB
EGAF00008025609 fastq.gz 6.6 GB
EGAF00008025610 fastq.gz 6.8 GB
EGAF00008025611 fastq.gz 6.7 GB
EGAF00008025612 fastq.gz 7.0 GB
EGAF00008025613 fastq.gz 6.0 GB
EGAF00008025614 fastq.gz 6.1 GB
EGAF00008025615 fastq.gz 4.4 GB
EGAF00008025616 fastq.gz 4.6 GB
EGAF00008025617 fastq.gz 6.0 GB
EGAF00008025618 fastq.gz 5.6 GB
EGAF00008025619 fastq.gz 7.1 GB
EGAF00008025620 fastq.gz 7.5 GB
EGAF00008025621 fastq.gz 5.1 GB
EGAF00008025622 fastq.gz 5.3 GB
EGAF00008025623 fastq.gz 6.0 GB
EGAF00008025624 fastq.gz 6.2 GB
EGAF00008025625 fastq.gz 7.0 GB
EGAF00008025626 fastq.gz 7.3 GB
EGAF00008025627 fastq.gz 4.5 GB
EGAF00008025628 fastq.gz 4.7 GB
EGAF00008025629 fastq.gz 7.4 GB
EGAF00008025630 fastq.gz 7.8 GB
EGAF00008025631 fastq.gz 3.5 GB
EGAF00008025632 fastq.gz 3.6 GB
EGAF00008025633 fastq.gz 3.4 GB
EGAF00008025634 fastq.gz 3.6 GB
EGAF00008025635 fastq.gz 3.0 GB
EGAF00008025636 fastq.gz 3.1 GB
EGAF00008025637 fastq.gz 3.0 GB
EGAF00008025638 fastq.gz 3.1 GB
EGAF00008025639 fastq.gz 6.4 GB
EGAF00008025640 fastq.gz 6.7 GB
EGAF00008025641 fastq.gz 6.3 GB
EGAF00008025642 fastq.gz 6.6 GB
EGAF00008025643 fastq.gz 6.4 GB
EGAF00008025644 fastq.gz 6.7 GB
EGAF00008025645 fastq.gz 6.9 GB
EGAF00008025646 fastq.gz 7.1 GB
EGAF00008025647 fastq.gz 4.2 GB
EGAF00008025648 fastq.gz 4.4 GB
EGAF00008025649 fastq.gz 4.8 GB
EGAF00008025650 fastq.gz 5.0 GB
EGAF00008025651 fastq.gz 2.9 GB
EGAF00008025652 fastq.gz 3.0 GB
EGAF00008025653 fastq.gz 2.9 GB
EGAF00008025654 fastq.gz 3.0 GB
EGAF00008025655 fastq.gz 3.0 GB
EGAF00008025656 fastq.gz 3.1 GB
EGAF00008025657 fastq.gz 3.0 GB
EGAF00008025658 fastq.gz 3.1 GB
EGAF00008025659 fastq.gz 3.0 GB
EGAF00008025660 fastq.gz 3.1 GB
EGAF00008025661 fastq.gz 2.9 GB
EGAF00008025662 fastq.gz 3.1 GB
EGAF00008025663 fastq.gz 2.2 GB
EGAF00008025664 fastq.gz 2.4 GB
EGAF00008025665 fastq.gz 2.3 GB
EGAF00008025666 fastq.gz 2.4 GB
EGAF00008025667 fastq.gz 2.9 GB
EGAF00008025668 fastq.gz 3.0 GB
EGAF00008025669 fastq.gz 2.9 GB
EGAF00008025670 fastq.gz 3.0 GB
EGAF00008025671 fastq.gz 6.5 GB
EGAF00008025672 fastq.gz 5.7 GB
EGAF00008025673 fastq.gz 8.1 GB
EGAF00008025674 fastq.gz 7.5 GB
EGAF00008025675 fastq.gz 3.1 GB
EGAF00008025676 fastq.gz 3.3 GB
EGAF00008025677 fastq.gz 3.2 GB
EGAF00008025678 fastq.gz 3.3 GB
EGAF00008025679 fastq.gz 7.0 GB
EGAF00008025680 fastq.gz 7.2 GB
EGAF00008025681 fastq.gz 3.2 GB
EGAF00008025682 fastq.gz 3.3 GB
EGAF00008025683 fastq.gz 3.2 GB
EGAF00008025684 fastq.gz 3.4 GB
EGAF00008025685 fastq.gz 5.0 GB
EGAF00008025686 fastq.gz 5.2 GB
84 Files (392.3 GB)