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As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis

This dataset contains raw sequencing files associated with the paper "Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis" (https://doi.org/10.1038/s41590-023-01490-5). It is composed of two experiments, which are as follows: 1. Single-cell profiling of whole blood leukocytes: This experiment comprises sequencing files generated using the BD Rhapsody single-cell multi-omics profiling (RNA + protein) platform. This platform was used to profile the whole blood leukocyte population in a cohort of sepsis patients, cardiac surgery controls and healthy controls. There are 48 samples and four files per sample: two paired-end FASTQ files (R1 and R2) corresponding to the RNA-seq library, and two paired-end FASTQ files (R1 and R2) corresponding to the protein profiling (ADT-based AbSeq) library. 2. Single-cell profiling of circulating HSPCs: This experiment comprises sequencing files generated using the 10X single-cell multi-omics (RNA-seq + ATAC-seq) profiling platform. This platform was used to profile circulating HSPCs in a cohort of sepsis patients and healthy controls. There are 5 samples (or plexes), each of which consists of a pool of individuals for whom cells were multiplexed and sequenced as a single sample. There are four files per sample: two paired-end FASTQ files (R1 and R2) corresponding to the RNA-seq library, and two paired-end FASTQ files (R1 and R2) corresponding to the ATAC-seq library. Because these samples consists of multiplexed pools, index files are also provided. These can be used for sample deconvolution using the Cell Ranger pipeline. NOTE: Due to EGA's constrains in the number of files permitted per sample, index files (I1 and I2) for the HSPC data set are provided as a separate experiment named "FASTQ index files (I1 and I2) for deconvolution of 10X single-cell multiomics libraries".

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Data access policy associated with the publication "Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis" (https://doi.org/10.1038/s41590-023-01490-5).

Same as for https://ega-archive.org/dacs/EGAC01000000009

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006283 Transcriptome Analysis

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF00008090673 fastq.gz 26.1 GB Report
EGAF00008090674 fastq.gz 27.6 GB Report
EGAF00008090675 fastq.gz 21.4 GB Report
EGAF00008090676 fastq.gz 22.5 GB Report
EGAF00008090677 fastq.gz 24.2 GB Report
EGAF00008090678 fastq.gz 25.5 GB Report
EGAF00008090679 fastq.gz 25.4 GB Report
EGAF00008090680 fastq.gz 26.3 GB Report
EGAF00008090681 fastq.gz 23.4 GB Report
EGAF00008090682 fastq.gz 24.2 GB Report
EGAF00008090683 fastq.gz 25.2 GB Report
EGAF00008090684 fastq.gz 26.1 GB Report
EGAF00008090685 fastq.gz 25.7 GB Report
EGAF00008090686 fastq.gz 27.0 GB Report
EGAF00008090687 fastq.gz 21.1 GB Report
EGAF00008090688 fastq.gz 22.0 GB Report
EGAF00008090689 fastq.gz 2.6 GB Report
EGAF00008090690 fastq.gz 2.6 GB Report
EGAF00008090691 fastq.gz 2.7 GB Report
EGAF00008090692 fastq.gz 2.8 GB Report
EGAF00008090693 fastq.gz 2.8 GB Report
EGAF00008090694 fastq.gz 2.8 GB Report
EGAF00008090695 fastq.gz 2.3 GB Report
EGAF00008090696 fastq.gz 2.3 GB Report
EGAF00008090697 fastq.gz 2.5 GB Report
EGAF00008090698 fastq.gz 2.5 GB Report
EGAF00008090699 fastq.gz 2.6 GB Report
EGAF00008090700 fastq.gz 2.7 GB Report
EGAF00008090701 fastq.gz 2.5 GB Report
EGAF00008090702 fastq.gz 2.5 GB Report
EGAF00008090703 fastq.gz 2.8 GB Report
EGAF00008090704 fastq.gz 2.8 GB Report
EGAF00008090705 fastq.gz 25.5 GB Report
EGAF00008090706 fastq.gz 27.0 GB Report
EGAF00008090707 fastq.gz 21.2 GB Report
EGAF00008090708 fastq.gz 22.3 GB Report
EGAF00008090709 fastq.gz 21.9 GB Report
EGAF00008090710 fastq.gz 22.6 GB Report
EGAF00008090711 fastq.gz 22.4 GB Report
EGAF00008090712 fastq.gz 23.5 GB Report
EGAF00008090713 fastq.gz 19.0 GB Report
EGAF00008090714 fastq.gz 20.3 GB Report
EGAF00008090715 fastq.gz 22.3 GB Report
EGAF00008090716 fastq.gz 23.6 GB Report
EGAF00008090717 fastq.gz 25.3 GB Report
EGAF00008090718 fastq.gz 26.5 GB Report
EGAF00008090719 fastq.gz 20.7 GB Report
EGAF00008090720 fastq.gz 21.5 GB Report
EGAF00008090721 fastq.gz 2.3 GB Report
EGAF00008090722 fastq.gz 2.3 GB Report
EGAF00008090723 fastq.gz 2.2 GB Report
EGAF00008090724 fastq.gz 2.2 GB Report
EGAF00008090725 fastq.gz 2.4 GB Report
EGAF00008090726 fastq.gz 2.4 GB Report
EGAF00008090727 fastq.gz 1.9 GB Report
EGAF00008090728 fastq.gz 1.9 GB Report
EGAF00008090729 fastq.gz 1.8 GB Report
EGAF00008090730 fastq.gz 1.8 GB Report
EGAF00008090731 fastq.gz 2.3 GB Report
EGAF00008090732 fastq.gz 2.3 GB Report
EGAF00008090733 fastq.gz 2.2 GB Report
EGAF00008090734 fastq.gz 2.2 GB Report
EGAF00008090735 fastq.gz 2.5 GB Report
EGAF00008090736 fastq.gz 2.5 GB Report
EGAF00008090737 fastq.gz 22.9 GB Report
EGAF00008090738 fastq.gz 24.2 GB Report
EGAF00008090739 fastq.gz 22.3 GB Report
EGAF00008090740 fastq.gz 23.6 GB Report
EGAF00008090741 fastq.gz 20.4 GB Report
EGAF00008090742 fastq.gz 21.7 GB Report
EGAF00008090743 fastq.gz 28.4 GB Report
EGAF00008090744 fastq.gz 29.5 GB Report
EGAF00008090745 fastq.gz 17.2 GB Report
EGAF00008090746 fastq.gz 18.4 GB Report
EGAF00008090747 fastq.gz 22.4 GB Report
EGAF00008090748 fastq.gz 23.8 GB Report
EGAF00008090749 fastq.gz 19.1 GB Report
EGAF00008090750 fastq.gz 20.6 GB Report
EGAF00008090751 fastq.gz 17.5 GB Report
EGAF00008090752 fastq.gz 18.6 GB Report
EGAF00008090753 fastq.gz 1.9 GB Report
EGAF00008090754 fastq.gz 1.9 GB Report
EGAF00008090755 fastq.gz 2.1 GB Report
EGAF00008090756 fastq.gz 2.2 GB Report
EGAF00008090757 fastq.gz 2.3 GB Report
EGAF00008090758 fastq.gz 2.3 GB Report
EGAF00008090759 fastq.gz 2.0 GB Report
EGAF00008090760 fastq.gz 2.0 GB Report
EGAF00008090761 fastq.gz 2.0 GB Report
EGAF00008090762 fastq.gz 2.1 GB Report
EGAF00008090763 fastq.gz 2.1 GB Report
EGAF00008090764 fastq.gz 2.1 GB Report
EGAF00008090765 fastq.gz 2.2 GB Report
EGAF00008090766 fastq.gz 2.2 GB Report
EGAF00008090767 fastq.gz 1.9 GB Report
EGAF00008090768 fastq.gz 1.9 GB Report
EGAF00008090769 fastq.gz 22.4 GB Report
EGAF00008090770 fastq.gz 23.6 GB Report
EGAF00008090771 fastq.gz 18.8 GB Report
EGAF00008090772 fastq.gz 19.9 GB Report
EGAF00008090773 fastq.gz 20.0 GB Report
EGAF00008090774 fastq.gz 21.1 GB Report
EGAF00008090775 fastq.gz 20.7 GB Report
EGAF00008090776 fastq.gz 21.8 GB Report
EGAF00008090777 fastq.gz 16.1 GB Report
EGAF00008090778 fastq.gz 17.5 GB Report
EGAF00008090779 fastq.gz 22.3 GB Report
EGAF00008090780 fastq.gz 23.9 GB Report
EGAF00008090781 fastq.gz 23.6 GB Report
EGAF00008090782 fastq.gz 24.8 GB Report
EGAF00008090783 fastq.gz 22.5 GB Report
EGAF00008090784 fastq.gz 23.2 GB Report
EGAF00008090785 fastq.gz 2.6 GB Report
EGAF00008090786 fastq.gz 2.7 GB Report
EGAF00008090787 fastq.gz 2.5 GB Report
EGAF00008090788 fastq.gz 2.5 GB Report
EGAF00008090789 fastq.gz 2.4 GB Report
EGAF00008090790 fastq.gz 2.4 GB Report
EGAF00008090791 fastq.gz 2.1 GB Report
EGAF00008090792 fastq.gz 2.1 GB Report
EGAF00008090793 fastq.gz 1.9 GB Report
EGAF00008090794 fastq.gz 1.9 GB Report
EGAF00008090795 fastq.gz 2.5 GB Report
EGAF00008090796 fastq.gz 2.5 GB Report
EGAF00008090797 fastq.gz 2.4 GB Report
EGAF00008090798 fastq.gz 2.4 GB Report
EGAF00008090799 fastq.gz 2.6 GB Report
EGAF00008090800 fastq.gz 2.6 GB Report
EGAF00008090801 fastq.gz 20.5 GB Report
EGAF00008090802 fastq.gz 21.7 GB Report
EGAF00008090803 fastq.gz 18.4 GB Report
EGAF00008090804 fastq.gz 19.9 GB Report
EGAF00008090805 fastq.gz 18.6 GB Report
EGAF00008090806 fastq.gz 19.8 GB Report
EGAF00008090807 fastq.gz 19.5 GB Report
EGAF00008090808 fastq.gz 20.5 GB Report
EGAF00008090809 fastq.gz 19.2 GB Report
EGAF00008090810 fastq.gz 20.6 GB Report
EGAF00008090811 fastq.gz 18.4 GB Report
EGAF00008090812 fastq.gz 19.8 GB Report
EGAF00008090813 fastq.gz 20.9 GB Report
EGAF00008090814 fastq.gz 22.6 GB Report
EGAF00008090815 fastq.gz 19.3 GB Report
EGAF00008090816 fastq.gz 20.4 GB Report
EGAF00008090817 fastq.gz 2.2 GB Report
EGAF00008090818 fastq.gz 2.2 GB Report
EGAF00008090819 fastq.gz 2.1 GB Report
EGAF00008090820 fastq.gz 2.1 GB Report
EGAF00008090821 fastq.gz 2.1 GB Report
EGAF00008090822 fastq.gz 2.1 GB Report
EGAF00008090823 fastq.gz 1.7 GB Report
EGAF00008090824 fastq.gz 1.7 GB Report
EGAF00008090825 fastq.gz 1.7 GB Report
EGAF00008090826 fastq.gz 1.7 GB Report
EGAF00008090827 fastq.gz 1.9 GB Report
EGAF00008090828 fastq.gz 1.9 GB Report
EGAF00008090829 fastq.gz 1.7 GB Report
EGAF00008090830 fastq.gz 1.7 GB Report
EGAF00008090831 fastq.gz 2.0 GB Report
EGAF00008090832 fastq.gz 2.0 GB Report
EGAF00008090833 fastq.gz 22.4 GB Report
EGAF00008090834 fastq.gz 24.0 GB Report
EGAF00008090835 fastq.gz 17.9 GB Report
EGAF00008090836 fastq.gz 19.4 GB Report
EGAF00008090837 fastq.gz 19.3 GB Report
EGAF00008090838 fastq.gz 20.7 GB Report
EGAF00008090839 fastq.gz 21.8 GB Report
EGAF00008090840 fastq.gz 23.4 GB Report
EGAF00008090841 fastq.gz 19.4 GB Report
EGAF00008090842 fastq.gz 20.9 GB Report
EGAF00008090843 fastq.gz 21.2 GB Report
EGAF00008090844 fastq.gz 22.9 GB Report
EGAF00008090845 fastq.gz 21.8 GB Report
EGAF00008090846 fastq.gz 23.5 GB Report
EGAF00008090847 fastq.gz 21.4 GB Report
EGAF00008090848 fastq.gz 22.5 GB Report
EGAF00008090849 fastq.gz 2.1 GB Report
EGAF00008090850 fastq.gz 2.1 GB Report
EGAF00008090851 fastq.gz 2.1 GB Report
EGAF00008090852 fastq.gz 2.1 GB Report
EGAF00008090853 fastq.gz 2.1 GB Report
EGAF00008090854 fastq.gz 2.1 GB Report
EGAF00008090855 fastq.gz 1.8 GB Report
EGAF00008090856 fastq.gz 1.8 GB Report
EGAF00008090857 fastq.gz 1.9 GB Report
EGAF00008090858 fastq.gz 1.9 GB Report
EGAF00008090859 fastq.gz 2.1 GB Report
EGAF00008090860 fastq.gz 2.1 GB Report
EGAF00008090861 fastq.gz 2.0 GB Report
EGAF00008090862 fastq.gz 2.1 GB Report
EGAF00008090863 fastq.gz 2.1 GB Report
EGAF00008090864 fastq.gz 2.1 GB Report
EGAF00008090865 fastq.gz 1.6 GB Report
EGAF00008090866 fastq.gz 3.6 GB Report
EGAF00008090867 fastq.gz 7.3 GB Report
EGAF00008090868 fastq.gz 7.3 GB Report
EGAF00008090869 fastq.gz 3.1 GB Report
EGAF00008090870 fastq.gz 3.3 GB Report
EGAF00008090871 fastq.gz 54.4 GB Report
EGAF00008090872 fastq.gz 45.1 GB Report
EGAF00008090873 fastq.gz 1.7 GB Report
EGAF00008090874 fastq.gz 4.0 GB Report
EGAF00008090875 fastq.gz 8.0 GB Report
EGAF00008090876 fastq.gz 8.2 GB Report
EGAF00008090877 fastq.gz 3.4 GB Report
EGAF00008090878 fastq.gz 3.6 GB Report
EGAF00008090879 fastq.gz 62.0 GB Report
EGAF00008090880 fastq.gz 49.6 GB Report
EGAF00008090881 fastq.gz 1.8 GB Report
EGAF00008090882 fastq.gz 4.1 GB Report
EGAF00008090883 fastq.gz 8.2 GB Report
EGAF00008090884 fastq.gz 8.3 GB Report
EGAF00008090885 fastq.gz 3.6 GB Report
EGAF00008090886 fastq.gz 3.7 GB Report
EGAF00008090887 fastq.gz 64.7 GB Report
EGAF00008090888 fastq.gz 52.4 GB Report
EGAF00008090889 fastq.gz 1.9 GB Report
EGAF00008090890 fastq.gz 4.4 GB Report
EGAF00008090891 fastq.gz 8.7 GB Report
EGAF00008090892 fastq.gz 8.7 GB Report
EGAF00008090893 fastq.gz 3.5 GB Report
EGAF00008090894 fastq.gz 3.7 GB Report
EGAF00008090895 fastq.gz 60.5 GB Report
EGAF00008090896 fastq.gz 49.3 GB Report
EGAF00008090897 fastq.gz 1.6 GB Report
EGAF00008090898 fastq.gz 3.7 GB Report
EGAF00008090899 fastq.gz 7.5 GB Report
EGAF00008090900 fastq.gz 7.6 GB Report
EGAF00008090901 fastq.gz 3.5 GB Report
EGAF00008090902 fastq.gz 3.4 GB Report
EGAF00008090903 fastq.gz 57.5 GB Report
EGAF00008090904 fastq.gz 46.8 GB Report
232 Files (3.0 TB)