About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Single cell RNA-seq, TCR-seq and bulk TCR-seq on HNSCC patients treated with ICB

We performed single cell RNA- and TCR-sequencing (10x Genomics) on immune infiltrates (CD45+ cells) from 18 HNSCC patients enrolled in the IMCISION trial (Vos et al. 2021). Viable immune cells were isolated from pre-treatment and post-treatment primary tumor biopsies of 10 patients responding (1 partial pathological response and 9 major pathological responses) and 7 patients non-responding to anti-PD-1 and anti-CTLA4 combination immunotherapy. One patient treated with anti-PD-1 monotherapy (1 major pathological response) was included in the dataset. Bulk TCR-seq was performed on the PBMCs of responding patients, pre- and post-treatment.

Request Access

DAC for requesting access to the single cell datasets (scRNAseq and scTCRseq) and bulk TCR on HNSCC patients treated with neoadj NIVO/IPI.

To request access to the single cell datasets on HNSCC patients treated with neoadj NIVO/IPI, please provide the following information in your Data Access Request: - Recipient and Recipient Institution - Details of dataset requested, i.e. EGA Study and Dataset Accession Number(s) - Brief abstract of the Project in which the Data will be used (500 words max.) - All Individuals who will be allowed access to the requested datasets by the Recipient Institution. After receipt and review of your Data Access Request by the Data Access Committee, you will receive a Data Transfer Agreement to be completed, signed and returned to KT&C and the Data Access Committee, prior to being granted access to the requested dataset(s). For the avoidance of doubt, the Data Access Committee reserves the right to withhold granting access.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007368 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF00008202428 fastq.gz 77.1 MB Report
EGAF00008202429 fastq.gz 192.4 MB Report
EGAF00008202430 fastq.gz 105.2 MB Report
EGAF00008202431 fastq.gz 262.4 MB Report
EGAF00008202432 fastq.gz 76.5 MB Report
EGAF00008202433 fastq.gz 190.4 MB Report
EGAF00008202434 fastq.gz 1.0 GB Report
EGAF00008202435 fastq.gz 3.5 GB Report
EGAF00008202436 fastq.gz 840.6 MB Report
EGAF00008202437 fastq.gz 2.9 GB Report
EGAF00008202438 fastq.gz 564.7 MB Report
EGAF00008202439 fastq.gz 1.9 GB Report
EGAF00008202440 fastq.gz 746.0 MB Report
EGAF00008202441 fastq.gz 2.6 GB Report
EGAF00008202442 fastq.gz 784.3 MB Report
EGAF00008202443 fastq.gz 2.7 GB Report
EGAF00008202444 fastq.gz 373.8 MB Report
EGAF00008202445 fastq.gz 642.0 MB Report
EGAF00008202446 fastq.gz 500.3 MB Report
EGAF00008202447 fastq.gz 861.9 MB Report
EGAF00008202448 fastq.gz 165.4 MB Report
EGAF00008202449 fastq.gz 511.9 MB Report
EGAF00008202450 fastq.gz 125.9 MB Report
EGAF00008202451 fastq.gz 384.4 MB Report
EGAF00008202452 fastq.gz 241.4 MB Report
EGAF00008202453 fastq.gz 740.8 MB Report
EGAF00008202454 fastq.gz 57.4 MB Report
EGAF00008202455 fastq.gz 142.3 MB Report
EGAF00008202456 fastq.gz 71.8 MB Report
EGAF00008202457 fastq.gz 178.9 MB Report
EGAF00008202458 fastq.gz 128.1 MB Report
EGAF00008202459 fastq.gz 255.1 MB Report
EGAF00008202460 fastq.gz 121.3 MB Report
EGAF00008202461 fastq.gz 241.2 MB Report
EGAF00008202462 fastq.gz 119.3 MB Report
EGAF00008202463 fastq.gz 238.6 MB Report
EGAF00008202464 fastq.gz 95.7 MB Report
EGAF00008202465 fastq.gz 190.4 MB Report
EGAF00008202466 fastq.gz 40.9 MB Report
EGAF00008202467 fastq.gz 60.0 MB Report
EGAF00008202468 fastq.gz 38.9 MB Report
EGAF00008202469 fastq.gz 57.0 MB Report
EGAF00008202470 fastq.gz 38.0 MB Report
EGAF00008202471 fastq.gz 55.9 MB Report
EGAF00008202472 fastq.gz 30.5 MB Report
EGAF00008202473 fastq.gz 44.7 MB Report
EGAF00008202474 fastq.gz 30.2 MB Report
EGAF00008202475 fastq.gz 44.4 MB Report
EGAF00008202476 fastq.gz 23.3 MB Report
EGAF00008202477 fastq.gz 34.2 MB Report
EGAF00008202478 fastq.gz 21.1 MB Report
EGAF00008202479 fastq.gz 31.0 MB Report
EGAF00008202480 fastq.gz 26.2 MB Report
EGAF00008202481 fastq.gz 38.5 MB Report
EGAF00008202482 fastq.gz 17.4 MB Report
EGAF00008202483 fastq.gz 25.5 MB Report
EGAF00008202484 fastq.gz 25.8 MB Report
EGAF00008202485 fastq.gz 38.1 MB Report
EGAF00008202486 fastq.gz 13.1 MB Report
EGAF00008202487 fastq.gz 19.2 MB Report
EGAF00008202488 fastq.gz 25.5 MB Report
EGAF00008202489 fastq.gz 37.7 MB Report
EGAF00008202490 fastq.gz 13.8 MB Report
EGAF00008202491 fastq.gz 20.2 MB Report
EGAF00008202492 fastq.gz 15.3 MB Report
EGAF00008202493 fastq.gz 22.4 MB Report
EGAF00008202494 fastq.gz 13.8 MB Report
EGAF00008202495 fastq.gz 20.3 MB Report
EGAF00008202496 fastq.gz 16.0 MB Report
EGAF00008202497 fastq.gz 23.3 MB Report
EGAF00008202498 fastq.gz 35.7 MB Report
EGAF00008202499 fastq.gz 52.5 MB Report
EGAF00008202500 fastq.gz 39.4 MB Report
EGAF00008202501 fastq.gz 58.0 MB Report
EGAF00008202502 fastq.gz 34.8 MB Report
EGAF00008202503 fastq.gz 51.0 MB Report
EGAF00008202504 fastq.gz 30.3 MB Report
EGAF00008202505 fastq.gz 44.4 MB Report
EGAF00008202506 fastq.gz 76.4 MB Report
EGAF00008202507 fastq.gz 113.2 MB Report
EGAF00008202508 fastq.gz 93.5 MB Report
EGAF00008202509 fastq.gz 138.3 MB Report
EGAF00008202510 fastq.gz 92.2 MB Report
EGAF00008202511 fastq.gz 136.4 MB Report
EGAF00008202512 fastq.gz 92.6 MB Report
EGAF00008202513 fastq.gz 137.3 MB Report
EGAF00008202514 fastq.gz 74.4 MB Report
EGAF00008202515 fastq.gz 110.0 MB Report
EGAF00008202516 fastq.gz 35.0 MB Report
EGAF00008202517 fastq.gz 51.8 MB Report
EGAF00008202518 fastq.gz 63.5 MB Report
EGAF00008202519 fastq.gz 93.9 MB Report
EGAF00008202520 fastq.gz 43.0 MB Report
EGAF00008202521 fastq.gz 63.6 MB Report
EGAF00008202522 fastq.gz 915.5 MB Report
EGAF00008202523 fastq.gz 3.1 GB Report
EGAF00008202524 fastq.gz 674.8 MB Report
EGAF00008202525 fastq.gz 2.3 GB Report
EGAF00008202526 fastq.gz 1.2 GB Report
EGAF00008202527 fastq.gz 4.1 GB Report
EGAF00008202528 fastq.gz 357.5 MB Report
EGAF00008202529 fastq.gz 615.3 MB Report
EGAF00008202530 fastq.gz 406.0 MB Report
EGAF00008202531 fastq.gz 704.0 MB Report
EGAF00008202532 fastq.gz 339.5 MB Report
EGAF00008202533 fastq.gz 586.3 MB Report
EGAF00008202534 fastq.gz 456.1 MB Report
EGAF00008202535 fastq.gz 789.2 MB Report
EGAF00008202536 fastq.gz 326.9 MB Report
EGAF00008202537 fastq.gz 565.5 MB Report
EGAF00008202538 fastq.gz 370.6 MB Report
EGAF00008202539 fastq.gz 646.4 MB Report
EGAF00008202540 fastq.gz 243.5 MB Report
EGAF00008202541 fastq.gz 415.3 MB Report
EGAF00008202542 fastq.gz 242.4 MB Report
EGAF00008202543 fastq.gz 412.6 MB Report
EGAF00008202544 fastq.gz 221.6 MB Report
EGAF00008202545 fastq.gz 378.3 MB Report
EGAF00008202546 fastq.gz 264.3 MB Report
EGAF00008202547 fastq.gz 452.6 MB Report
EGAF00008202548 fastq.gz 141.0 MB Report
EGAF00008202549 fastq.gz 236.5 MB Report
EGAF00008202550 fastq.gz 120.7 MB Report
EGAF00008202551 fastq.gz 201.9 MB Report
EGAF00008202552 fastq.gz 195.8 MB Report
EGAF00008202553 fastq.gz 328.8 MB Report
EGAF00008202554 fastq.gz 195.5 MB Report
EGAF00008202555 fastq.gz 329.6 MB Report
EGAF00008202556 fastq.gz 596.9 MB Report
EGAF00008202557 fastq.gz 941.9 MB Report
EGAF00008202558 fastq.gz 595.3 MB Report
EGAF00008202559 fastq.gz 938.2 MB Report
EGAF00008202560 fastq.gz 545.8 MB Report
EGAF00008202561 fastq.gz 860.0 MB Report
EGAF00008202562 fastq.gz 648.7 MB Report
EGAF00008202563 fastq.gz 1.0 GB Report
EGAF00008202564 fastq.gz 204.9 MB Report
EGAF00008202565 fastq.gz 315.9 MB Report
EGAF00008202566 fastq.gz 176.3 MB Report
EGAF00008202567 fastq.gz 271.5 MB Report
EGAF00008202568 fastq.gz 279.6 MB Report
EGAF00008202569 fastq.gz 431.3 MB Report
EGAF00008202570 fastq.gz 284.2 MB Report
EGAF00008202571 fastq.gz 440.9 MB Report
EGAF00008202572 fastq.gz 180.3 MB Report
EGAF00008202573 fastq.gz 305.0 MB Report
EGAF00008202574 fastq.gz 118.4 MB Report
EGAF00008202575 fastq.gz 200.1 MB Report
EGAF00008202576 fastq.gz 85.2 MB Report
EGAF00008202577 fastq.gz 144.0 MB Report
EGAF00008202578 fastq.gz 87.6 MB Report
EGAF00008202579 fastq.gz 148.6 MB Report
EGAF00008202580 fastq.gz 43.6 MB Report
EGAF00008202581 fastq.gz 67.3 MB Report
EGAF00008202582 fastq.gz 28.7 MB Report
EGAF00008202583 fastq.gz 44.3 MB Report
EGAF00008202584 fastq.gz 20.7 MB Report
EGAF00008202585 fastq.gz 31.9 MB Report
EGAF00008202586 fastq.gz 21.2 MB Report
EGAF00008202587 fastq.gz 33.0 MB Report
EGAF00008202588 fastq.gz 260.6 MB Report
EGAF00008202589 fastq.gz 441.3 MB Report
EGAF00008202590 fastq.gz 298.6 MB Report
EGAF00008202591 fastq.gz 515.8 MB Report
EGAF00008202592 fastq.gz 365.9 MB Report
EGAF00008202593 fastq.gz 623.8 MB Report
EGAF00008202594 fastq.gz 272.0 MB Report
EGAF00008202595 fastq.gz 463.9 MB Report
EGAF00008202596 fastq.gz 650.2 MB Report
EGAF00008202597 fastq.gz 1.0 GB Report
EGAF00008202598 fastq.gz 742.2 MB Report
EGAF00008202599 fastq.gz 1.2 GB Report
EGAF00008202600 fastq.gz 908.6 MB Report
EGAF00008202601 fastq.gz 1.4 GB Report
EGAF00008202602 fastq.gz 679.5 MB Report
EGAF00008202603 fastq.gz 1.1 GB Report
EGAF00008202604 fastq.gz 834.4 MB Report
EGAF00008202605 fastq.gz 1.5 GB Report
EGAF00008202606 fastq.gz 770.3 MB Report
EGAF00008202607 fastq.gz 1.4 GB Report
EGAF00008202608 fastq.gz 900.2 MB Report
EGAF00008202609 fastq.gz 1.6 GB Report
EGAF00008202610 fastq.gz 23.8 MB Report
EGAF00008202611 fastq.gz 40.6 MB Report
EGAF00008202612 fastq.gz 439.0 MB Report
EGAF00008202613 fastq.gz 762.6 MB Report
EGAF00008202614 fastq.gz 570.2 MB Report
EGAF00008202615 fastq.gz 998.1 MB Report
EGAF00008202616 fastq.gz 220.8 MB Report
EGAF00008202617 fastq.gz 381.1 MB Report
EGAF00008202618 fastq.gz 572.0 MB Report
EGAF00008202619 fastq.gz 995.9 MB Report
EGAF00008202620 fastq.gz 1.1 GB Report
EGAF00008202621 fastq.gz 1.7 GB Report
EGAF00008202622 fastq.gz 986.2 MB Report
EGAF00008202623 fastq.gz 1.6 GB Report
EGAF00008202624 fastq.gz 1.2 GB Report
EGAF00008202625 fastq.gz 1.9 GB Report
EGAF00008202626 fastq.gz 31.6 MB Report
EGAF00008202627 fastq.gz 49.6 MB Report
EGAF00008202628 fastq.gz 401.8 MB Report
EGAF00008202629 fastq.gz 637.4 MB Report
EGAF00008202630 fastq.gz 518.1 MB Report
EGAF00008202631 fastq.gz 833.0 MB Report
EGAF00008202632 fastq.gz 201.4 MB Report
EGAF00008202633 fastq.gz 317.8 MB Report
EGAF00008202634 fastq.gz 519.8 MB Report
EGAF00008202635 fastq.gz 827.2 MB Report
EGAF00008202636 fastq.gz 160.4 MB Report
EGAF00008202637 fastq.gz 491.2 MB Report
EGAF00008202638 fastq.gz 185.8 MB Report
EGAF00008202639 fastq.gz 569.6 MB Report
EGAF00008202640 fastq.gz 345.2 MB Report
EGAF00008202641 fastq.gz 1.1 GB Report
EGAF00008202642 fastq.gz 200.6 MB Report
EGAF00008202643 fastq.gz 615.4 MB Report
EGAF00008202644 fastq.gz 221.4 MB Report
EGAF00008202645 fastq.gz 692.8 MB Report
EGAF00008202646 fastq.gz 295.7 MB Report
EGAF00008202647 fastq.gz 698.0 MB Report
EGAF00008202648 fastq.gz 418.8 MB Report
EGAF00008202649 fastq.gz 990.4 MB Report
EGAF00008202650 fastq.gz 309.1 MB Report
EGAF00008202651 fastq.gz 733.5 MB Report
EGAF00008202652 fastq.gz 277.1 MB Report
EGAF00008202653 fastq.gz 655.7 MB Report
EGAF00008202654 fastq.gz 64.9 MB Report
EGAF00008202655 fastq.gz 227.0 MB Report
EGAF00008202656 fastq.gz 80.3 MB Report
EGAF00008202657 fastq.gz 267.9 MB Report
EGAF00008202658 fastq.gz 103.1 MB Report
EGAF00008202659 fastq.gz 350.9 MB Report
EGAF00008202660 fastq.gz 73.0 MB Report
EGAF00008202661 fastq.gz 242.3 MB Report
EGAF00008202662 fastq.gz 51.1 MB Report
EGAF00008202663 fastq.gz 170.0 MB Report
EGAF00008202664 fastq.gz 39.9 MB Report
EGAF00008202665 fastq.gz 133.9 MB Report
EGAF00008202666 fastq.gz 77.1 MB Report
EGAF00008202667 fastq.gz 258.4 MB Report
EGAF00008202668 fastq.gz 68.1 MB Report
EGAF00008202669 fastq.gz 225.8 MB Report
EGAF00008202670 fastq.gz 40.6 MB Report
EGAF00008202671 fastq.gz 133.8 MB Report
EGAF00008202672 fastq.gz 49.6 MB Report
EGAF00008202673 fastq.gz 174.0 MB Report
EGAF00008202674 fastq.gz 38.0 MB Report
EGAF00008202675 fastq.gz 125.2 MB Report
EGAF00008202676 fastq.gz 37.6 MB Report
EGAF00008202677 fastq.gz 123.7 MB Report
EGAF00008202678 fastq.gz 93.3 MB Report
EGAF00008202679 fastq.gz 310.2 MB Report
EGAF00008202680 fastq.gz 116.7 MB Report
EGAF00008202681 fastq.gz 401.7 MB Report
EGAF00008202682 fastq.gz 89.3 MB Report
EGAF00008202683 fastq.gz 297.2 MB Report
EGAF00008202684 fastq.gz 75.6 MB Report
EGAF00008202685 fastq.gz 252.5 MB Report
EGAF00008202686 fastq.gz 145.7 MB Report
EGAF00008202687 fastq.gz 489.1 MB Report
EGAF00008202688 fastq.gz 227.1 MB Report
EGAF00008202689 fastq.gz 768.1 MB Report
EGAF00008202690 fastq.gz 235.0 MB Report
EGAF00008202691 fastq.gz 812.6 MB Report
EGAF00008202692 fastq.gz 218.0 MB Report
EGAF00008202693 fastq.gz 738.3 MB Report
EGAF00008202694 fastq.gz 112.1 MB Report
EGAF00008202695 fastq.gz 395.4 MB Report
EGAF00008202696 fastq.gz 147.3 MB Report
EGAF00008202697 fastq.gz 493.4 MB Report
EGAF00008202698 fastq.gz 154.5 MB Report
EGAF00008202699 fastq.gz 521.3 MB Report
EGAF00008202700 fastq.gz 111.0 MB Report
EGAF00008202701 fastq.gz 371.1 MB Report
274 Files (115.7 GB)