Genomic and transcriptomic landscape of T-cell lymphoblastic lymphoma compared to T-cell acute lymphoblastic leukemia: similar subtypes and different fusions
Due to the lower incidence of T-LBL and difficulties in obtaining diagnostic T-LBL material, extensive research on T-LBL has been hampered whereas genetic aberrations in T-ALL are thoroughly characterized. Given the similarities and differences between T-LBL and T-ALL, the question has been raised whether T-LBL and T-ALL represent two different diseases or different manifestations of the same disease. This study aims to identify the genomic and transcriptomic landscape of T-LBL and compare the findings to what is found T-ALL. Comparison of the molecular aberrations between T-LBL and T-ALL can provide insights into the overlap and differences in malignant development between the two entities, which could lead to improved risk stratification in T-LBL in order to eventually adapt T-LBL treatment protocols based on molecular-genetic prognostic factors.
- 02/04/2024
- 1 sample
- DAC: EGAC00001001864
DUO:0000007 version: 2021-02-23
disease specific research
This data use permission indicates that use is allowed provided it is related to the specified disease.
ModifiersMONDO_0006517
Data Access Agreement of data controlled by the Data Access Commitee of the Princess Maxima Center for Pediatric Oncology
The Princess Maxima Center for pediatric oncology default access policy to enable re-production of research and re-use of data for scientific purposes. Please contact the DAC (EGAC00001001864) for the most up to date policies.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001007099 | Other | |
| EGAS00001007767 | Other |
- Changed sample subject id
- Changed sample subject id
- Changed sample subject id
- Dataset Released
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
i
|
|---|---|---|---|---|
| EGAF00007984696 | cram | 4.0 GB | Report |
|
| EGAF00008422809 | cram | 2.6 GB | Report |
|
| EGAF00008422810 | cram | 3.3 GB | Report |
|
| EGAF00008422811 | cram | 3.6 GB | Report |
|
| EGAF00008422813 | cram | 1.4 GB | Report |
|
| EGAF00008422814 | cram | 1.2 GB | Report |
|
| EGAF00008422815 | cram | 1.3 GB | Report |
|
| EGAF00008422816 | cram | 2.5 GB | Report |
|
| EGAF00008422817 | cram | 2.9 GB | Report |
|
| EGAF00008422818 | cram | 3.7 GB | Report |
|
| EGAF00008422819 | cram | 1.2 GB | Report |
|
| EGAF00008422820 | cram | 2.9 GB | Report |
|
| EGAF00008422821 | cram | 3.7 GB | Report |
|
| EGAF00008422822 | cram | 4.9 GB | Report |
|
| EGAF00008422823 | cram | 1.8 GB | Report |
|
| EGAF00008422824 | cram | 3.7 GB | Report |
|
| EGAF00008422825 | cram | 1.9 GB | Report |
|
| EGAF00008422826 | cram | 3.9 GB | Report |
|
| EGAF00008422827 | cram | 5.4 GB | Report |
|
| EGAF00008422828 | cram | 6.1 GB | Report |
|
| EGAF00008422829 | cram | 3.0 GB | Report |
|
| EGAF00008422830 | cram | 3.6 GB | Report |
|
| EGAF00008422831 | cram | 1.6 GB | Report |
|
| EGAF00008422832 | cram | 1.7 GB | Report |
|
| EGAF00008422833 | cram | 4.7 GB | Report |
|
| EGAF00008422834 | cram | 5.3 GB | Report |
|
| EGAF00008422835 | cram | 3.0 GB | Report |
|
| EGAF00008422836 | cram | 7.1 GB | Report |
|
| EGAF00008422837 | cram | 3.1 GB | Report |
|
| 29 Files (95.0 GB) | ||||