RNA-seq data of Metabolic profiling of patient-derived organoids reveals nucleotide synthesis as a metabolic vulnerability in malignant rhabdoid tumors
Patient-matched normal kidney organoid (103H) and MRT tumoroid (103T2) models were treated for 24h with either DMSO (ctrl), 400nM MTX, or 50nM BAY to investigate the direct effects of drug treatment on the expression of key metabolic enzymes in the nucleotide biosynthesis pathways.
- 23/07/2024
- 1 sample
- DAC: EGAC00001001864
- Technology: Illumina NovaSeq X
DUO:0000007 version: 2021-02-23
disease specific research
This data use permission indicates that use is allowed provided it is related to the specified disease.
ModifiersMONDO_0006517
Data Access Agreement of data controlled by the Data Access Commitee of the Princess Maxima Center for Pediatric Oncology
The Princess Maxima Center for pediatric oncology default access policy to enable re-production of research and re-use of data for scientific purposes. Please contact the DAC (EGAC00001001864) for the most up to date policies.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001007877 | Other |
- Changed sample subject id
- Dataset Released
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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|---|---|---|---|---|
| EGAF00008512039 | bam | 2.5 GB | Report |
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| EGAF00008512040 | bam | 2.6 GB | Report |
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| EGAF00008512041 | bam | 2.4 GB | Report |
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| EGAF00008512042 | bam | 2.1 GB | Report |
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| EGAF00008512043 | bam | 2.6 GB | Report |
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| EGAF00008512044 | bam | 3.8 GB | Report |
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| EGAF00008512045 | bam | 3.5 GB | Report |
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| EGAF00008512046 | bam | 2.9 GB | Report |
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| EGAF00008512047 | bam | 4.7 GB | Report |
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| EGAF00008512048 | bam | 3.5 GB | Report |
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| EGAF00008512049 | bam | 2.2 GB | Report |
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| EGAF00008512050 | bam | 1.9 GB | Report |
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| 12 Files (34.6 GB) | ||||
