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RNA-seq data of Metabolic profiling of patient-derived organoids reveals nucleotide synthesis as a metabolic vulnerability in malignant rhabdoid tumors

Patient-matched normal kidney organoid (103H) and MRT tumoroid (103T2) models were treated for 24h with either DMSO (ctrl), 400nM MTX, or 50nM BAY to investigate the direct effects of drug treatment on the expression of key metabolic enzymes in the nucleotide biosynthesis pathways.

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DUO:0000007
version: 2021-02-23

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO_0006517

Data Access Agreement of data controlled by the Data Access Commitee of the Princess Maxima Center for Pediatric Oncology

The Princess Maxima Center for pediatric oncology default access policy to enable re-production of research and re-use of data for scientific purposes. Please contact the DAC (EGAC00001001864) for the most up to date policies.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007877 Other
  • Changed sample subject id
  • Dataset Released

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00008512039 bam 2.5 GB Report
EGAF00008512040 bam 2.6 GB Report
EGAF00008512041 bam 2.4 GB Report
EGAF00008512042 bam 2.1 GB Report
EGAF00008512043 bam 2.6 GB Report
EGAF00008512044 bam 3.8 GB Report
EGAF00008512045 bam 3.5 GB Report
EGAF00008512046 bam 2.9 GB Report
EGAF00008512047 bam 4.7 GB Report
EGAF00008512048 bam 3.5 GB Report
EGAF00008512049 bam 2.2 GB Report
EGAF00008512050 bam 1.9 GB Report
12 Files (34.6 GB)