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RNA-Seq Dataset of Organoid drug profiling identifies methotrexate as a therapy for SCCOHT, a rare pediatric cancer

We generated and characterized tumoroids from small cell carcinoma of the ovary, hypercalcemic type. Furthermore, we identified a drug that is selective and effective against SCCOHT tumoroids.

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DUO:0000007
version: 2021-02-23

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO_0006517

Data Access Agreement of data controlled by the Data Access Commitee of the Princess Maxima Center for Pediatric Oncology

The Princess Maxima Center for pediatric oncology default access policy to enable re-production of research and re-use of data for scientific purposes. Please contact the DAC (EGAC00001001864) for the most up to date policies.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007099 Other
EGAS00001007911 Other
  • Changed sample subject id
  • Changed sample subject id
  • Changed sample subject id
  • Dataset Released

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00007984712 cram 9.8 GB
EGAF00008619341 fastq.gz 956.5 MB
EGAF00008619342 fastq.gz 962.8 MB
EGAF00008619343 fastq.gz 907.6 MB
EGAF00008619344 fastq.gz 912.8 MB
EGAF00008619345 fastq.gz 886.0 MB
EGAF00008619346 fastq.gz 893.1 MB
EGAF00008619347 fastq.gz 1.0 GB
EGAF00008619348 fastq.gz 1.0 GB
EGAF00008619349 fastq.gz 909.4 MB
EGAF00008619350 fastq.gz 913.2 MB
EGAF00008619351 fastq.gz 946.3 MB
EGAF00008619352 fastq.gz 952.4 MB
EGAF00008619353 fastq.gz 1.2 GB
EGAF00008619354 fastq.gz 1.2 GB
EGAF00008619355 fastq.gz 1.0 GB
EGAF00008619356 fastq.gz 1.0 GB
EGAF00008619357 fastq.gz 924.4 MB
EGAF00008619358 fastq.gz 931.7 MB
EGAF00008619359 fastq.gz 967.4 MB
EGAF00008619360 fastq.gz 970.7 MB
EGAF00008619361 fastq.gz 1.1 GB
EGAF00008619362 fastq.gz 1.1 GB
EGAF00008619363 fastq.gz 1.3 GB
EGAF00008619364 fastq.gz 1.3 GB
EGAF00008619366 cram 6.4 GB
EGAF00008619369 cram 12.5 GB
EGAF00008619371 cram 5.4 GB
EGAF00008619373 cram 6.3 GB
EGAF00008619378 cram 6.2 GB
EGAF00008619379 cram 8.8 GB
EGAF00008619380 cram 6.4 GB
EGAF00008619384 cram 8.1 GB
EGAF00008619385 cram 5.0 GB
EGAF00008619386 cram 6.8 GB
EGAF00008619387 cram 3.7 GB
EGAF00008619388 cram 3.9 GB
37 Files (113.4 GB)