Transcriptomic data for Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers cell cycle arrest during hypoxic kidney injury

Transcriptomic data for manuscript titled: Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers cell cycle arrest during hypoxic kidney injury.

17/01/2025
16 samples
DAC: EGAC00001003512
Technology: NextSeq 2000

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID	Study Title	Study Type
EGAS00001007904	Tubulointerstitial fibrosis is the histological hallmark of chronic kidney disease (CKD). Hypoxia and inflammation (i.e., interleukin (IL)-1β signalling) are independent mediators of tubulointerstitial fibrosis. However, the physiological response of human kidney tubular cells to IL-1β/IL-1RI signalling under the hypoxic conditions of CKD is poorly understood and remains a clinical imperative for therapeutic targeting. This study reports that hypoxia and IL-1β act in synergy to trigger cell cycle arrest/cellular senescence of ex vivo patient-derived primary proximal tubular epithelial cells (PTECs).	Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID	File Type	Size
EGAF00008641221	fastq.gz	200.0 MB
EGAF00008641222	fastq.gz	200.0 MB
EGAF00008641223	fastq.gz	202.1 MB
EGAF00008641224	fastq.gz	203.3 MB
EGAF00008641225	fastq.gz	217.6 MB
EGAF00008641226	fastq.gz	220.0 MB
EGAF00008641227	fastq.gz	216.9 MB
EGAF00008641228	fastq.gz	219.9 MB
EGAF00008641229	fastq.gz	197.9 MB
EGAF00008641230	fastq.gz	198.2 MB
EGAF00008641231	fastq.gz	200.5 MB
EGAF00008641232	fastq.gz	201.6 MB
EGAF00008641233	fastq.gz	215.8 MB
EGAF00008641234	fastq.gz	217.9 MB
EGAF00008641235	fastq.gz	215.4 MB
EGAF00008641236	fastq.gz	218.1 MB
EGAF00008641237	fastq.gz	188.3 MB
EGAF00008641238	fastq.gz	188.5 MB
EGAF00008641239	fastq.gz	190.4 MB
EGAF00008641240	fastq.gz	191.4 MB
EGAF00008641241	fastq.gz	205.0 MB
EGAF00008641242	fastq.gz	207.4 MB
EGAF00008641243	fastq.gz	204.4 MB
EGAF00008641244	fastq.gz	207.6 MB
EGAF00008641245	fastq.gz	183.2 MB
EGAF00008641246	fastq.gz	183.3 MB
EGAF00008641247	fastq.gz	185.6 MB
EGAF00008641248	fastq.gz	186.5 MB
EGAF00008641249	fastq.gz	198.9 MB
EGAF00008641250	fastq.gz	200.8 MB
EGAF00008641251	fastq.gz	198.6 MB
EGAF00008641252	fastq.gz	201.1 MB
EGAF00008641253	fastq.gz	191.9 MB
EGAF00008641254	fastq.gz	192.3 MB
EGAF00008641255	fastq.gz	194.5 MB
EGAF00008641256	fastq.gz	195.8 MB
EGAF00008641257	fastq.gz	209.0 MB
EGAF00008641258	fastq.gz	211.5 MB
EGAF00008641259	fastq.gz	208.5 MB
EGAF00008641260	fastq.gz	211.8 MB
EGAF00008641261	fastq.gz	191.2 MB
EGAF00008641262	fastq.gz	191.9 MB
EGAF00008641263	fastq.gz	193.9 MB
EGAF00008641264	fastq.gz	195.1 MB
EGAF00008641265	fastq.gz	207.6 MB
EGAF00008641266	fastq.gz	210.3 MB
EGAF00008641267	fastq.gz	207.2 MB
EGAF00008641268	fastq.gz	210.6 MB
EGAF00008641269	fastq.gz	194.4 MB
EGAF00008641270	fastq.gz	194.9 MB
EGAF00008641271	fastq.gz	197.2 MB
EGAF00008641272	fastq.gz	198.4 MB
EGAF00008641273	fastq.gz	211.2 MB
EGAF00008641274	fastq.gz	213.9 MB
EGAF00008641275	fastq.gz	211.1 MB
EGAF00008641276	fastq.gz	214.1 MB
EGAF00008641277	fastq.gz	199.3 MB
EGAF00008641278	fastq.gz	199.7 MB
EGAF00008641279	fastq.gz	201.7 MB
EGAF00008641280	fastq.gz	202.8 MB
EGAF00008641281	fastq.gz	217.1 MB
EGAF00008641282	fastq.gz	219.8 MB
EGAF00008641283	fastq.gz	216.5 MB
EGAF00008641284	fastq.gz	219.7 MB
EGAF00008641285	fastq.gz	214.2 MB
EGAF00008641286	fastq.gz	214.6 MB
EGAF00008641287	fastq.gz	217.0 MB
EGAF00008641288	fastq.gz	218.1 MB
EGAF00008641289	fastq.gz	232.7 MB
EGAF00008641290	fastq.gz	235.0 MB
EGAF00008641291	fastq.gz	231.9 MB
EGAF00008641292	fastq.gz	235.1 MB
EGAF00008641293	fastq.gz	197.3 MB
EGAF00008641294	fastq.gz	197.8 MB
EGAF00008641295	fastq.gz	199.9 MB
EGAF00008641296	fastq.gz	201.0 MB
EGAF00008641297	fastq.gz	215.0 MB
EGAF00008641298	fastq.gz	217.5 MB
EGAF00008641299	fastq.gz	214.2 MB
EGAF00008641300	fastq.gz	217.5 MB
EGAF00008641301	fastq.gz	201.0 MB
EGAF00008641302	fastq.gz	201.5 MB
EGAF00008641303	fastq.gz	203.7 MB
EGAF00008641304	fastq.gz	204.7 MB
EGAF00008641305	fastq.gz	218.7 MB
EGAF00008641306	fastq.gz	221.3 MB
EGAF00008641307	fastq.gz	218.1 MB
EGAF00008641308	fastq.gz	221.1 MB
EGAF00008641309	fastq.gz	180.0 MB
EGAF00008641310	fastq.gz	180.6 MB
EGAF00008641311	fastq.gz	182.5 MB
EGAF00008641312	fastq.gz	183.4 MB
EGAF00008641313	fastq.gz	193.5 MB
EGAF00008641314	fastq.gz	195.7 MB
EGAF00008641315	fastq.gz	193.0 MB
EGAF00008641316	fastq.gz	195.7 MB
EGAF00008641317	fastq.gz	197.9 MB
EGAF00008641318	fastq.gz	197.9 MB
EGAF00008641319	fastq.gz	200.3 MB
EGAF00008641320	fastq.gz	201.4 MB
EGAF00008641321	fastq.gz	215.8 MB
EGAF00008641322	fastq.gz	217.9 MB
EGAF00008641323	fastq.gz	214.9 MB
EGAF00008641324	fastq.gz	218.1 MB
EGAF00008641325	fastq.gz	192.1 MB
EGAF00008641326	fastq.gz	192.6 MB
EGAF00008641327	fastq.gz	194.6 MB
EGAF00008641328	fastq.gz	195.8 MB
EGAF00008641329	fastq.gz	209.9 MB
EGAF00008641330	fastq.gz	212.5 MB
EGAF00008641331	fastq.gz	209.4 MB
EGAF00008641332	fastq.gz	212.4 MB
EGAF00008641333	fastq.gz	194.9 MB
EGAF00008641334	fastq.gz	195.3 MB
EGAF00008641335	fastq.gz	197.2 MB
EGAF00008641336	fastq.gz	198.1 MB
EGAF00008641337	fastq.gz	212.7 MB
EGAF00008641338	fastq.gz	215.2 MB
EGAF00008641339	fastq.gz	212.1 MB
EGAF00008641340	fastq.gz	215.2 MB
EGAF00008641341	fastq.gz	190.3 MB
EGAF00008641342	fastq.gz	190.8 MB
EGAF00008641343	fastq.gz	192.9 MB
EGAF00008641344	fastq.gz	193.9 MB
EGAF00008641345	fastq.gz	207.3 MB
EGAF00008641346	fastq.gz	209.5 MB
EGAF00008641347	fastq.gz	206.5 MB
EGAF00008641348	fastq.gz	209.6 MB
128 Files (26.2 GB)