Single-Cell DNA Methylation Profiling via scTAMseq
This dataset comprises single-cell DNA methylation and nuclear genotyping profiles of 7 total bone marrow aspirates (donors A.1-A.7) and 5 CD34+-enriched bone marrow samples (donors B.1-B.5) generated using the scTAMseq protocol. Sequencing was performed on the Mission Bio Tapestri platform, targeting a panel of 448 CpGs to assess epigenetic patterns and We also included 147 genomic regions commonly mutated in clonal hematopoiesis and 20 regions targeting chromosome Y. Samples B.1 & B.5, B.2 & B.4 and A.2 & A.5 were, in pairs, multiplexed into single tapestri lanes.
- 06/03/2025
- 9 samples
- DAC: EGAC00001003526
- Technology: Illumina NovaSeq 6000
Research use only. Project specific restriction
We will share data for scientific research upon reasonably justified requests. Users must present a signed Data Access Agreement available upon request. Terms of the DAA are not negotiable. Before asking for request through EGA, please email lars.velten@crg.eu
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001008056 | Other |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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| EGAF00008674373 | fastq.gz | 102.3 GB |
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| EGAF00008674374 | fastq.gz | 102.3 GB |
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| EGAF00008674375 | fastq.gz | 69.8 GB |
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| EGAF00008674376 | fastq.gz | 79.9 GB |
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| EGAF00008674377 | fastq.gz | 131.2 GB |
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| EGAF00008674378 | fastq.gz | 141.2 GB |
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| EGAF00008674379 | fastq.gz | 88.9 GB |
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| EGAF00008674380 | fastq.gz | 91.6 GB |
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| EGAF00008674381 | fastq.gz | 37.5 GB |
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| EGAF00008674382 | fastq.gz | 41.4 GB |
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| EGAF00008674383 | fastq.gz | 44.0 GB |
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| EGAF00008674384 | fastq.gz | 43.9 GB |
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| EGAF00008674385 | fastq.gz | 16.3 GB |
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| EGAF00008674386 | fastq.gz | 18.5 GB |
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| EGAF00008674387 | fastq.gz | 84.1 GB |
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| EGAF00008674388 | fastq.gz | 94.6 GB |
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| EGAF00008674389 | fastq.gz | 55.1 GB |
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| EGAF00008674390 | fastq.gz | 61.4 GB |
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| 18 Files (1.3 TB) | ||||
