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Low-coverage whole-genome sequencing (lcWGS) data of Genome in a Bottle (GIAB) reference samples

This dataset contains low-coverage whole-genome sequencing (lcWGS) data generated from three GIAB reference samples (HG001–HG003) for method benchmarking and concordance analysis in FFPE-GWAS workflows. The data were generated using Illumina NovaSeq with paired-end 150bp reads and downsampled to 2x coverage.

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Data Access Policy for FFPE-Based GWAS Data

Data access is controlled by the institutional Data Access Committee (DAC) at the Center for Human Genetics, Philipps-University Marburg. The DAC ensures that all data use complies with the informed consent provided by the study participants and adheres to applicable data protection regulations (e.g. GDPR). Researchers requesting access must: - Submit a detailed data access application specifying the research objectives. - Agree not to attempt re-identification of any participant. - Use the data exclusively for the approved project and not share it with third parties. - Acknowledge the source of the data in any publication or presentation. - Agree to destroy the data after completion of the project, unless further use is approved. The DAC will evaluate requests based on scientific merit, compatibility with participant consent, and data security provisions. Access will be granted for a defined time period, subject to renewal.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001008103 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00008722281 fq.gz 3.9 GB
EGAF00008722282 fq.gz 4.2 GB
EGAF00008722283 fq.gz 4.7 GB
EGAF00008722284 fq.gz 4.8 GB
EGAF00008722285 fq.gz 3.1 GB
EGAF00008722286 fq.gz 3.1 GB
6 Files (23.9 GB)