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Whole exome sequencing data for paired non-serous endometrial and ovarian carcinomas from 27 patients with concurrent tumours.

Dataset for Synchronous Endometrial and Ovarian Cancer

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Data Access Agreement based on the EGA agreement, with modifications from the University of Edinburgh. Please contact the Data Access Committee for a copy of the form to request access. Synchronous Endometrial and Ovarian Cancer.

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access (the “Data Access Agreement”). By signing this Agreement, the User Institution agrees to be bound by these terms and conditions. Definitions Agreement: means this Data Access Agreement. Authorised Personnel: The individuals at the User Institution to whom the Provider Institution grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access and as set out in Appendix II. Data Producers: The Provider Institution and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. EGA: The European Genome-phenome Archive. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. File Access Security: The minimum standard of file access security measures as set out in Appendix I Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean non-commercial research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. Provider Institution: The Institute of Genetics and Cancer at the University of Edinburgh, a charitable body registered in Scotland (registration number SC005336), incorporated under the Universities (Scotland) Acts and having its administrative offices located at Old College, South Bridge, Edinburgh, EH8 9YL. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to comply with the File Access Security policy set out in Appendix I to protect these Data. 3. The User Institution agrees to undertake to protect the confidentiality of Research Participants in any research papers or publications that they prepare and/or publish by taking all best endeavours to ensure the identities of Research Participants are not disclosed. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application and Data Access Agreement for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards of damages and payments made by the User Institution that may arise (whether directly or indirectly) in any way whatsoever from the User Institution’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (https://www.genome.gov/Pages/Research/WellcomeReport0303.pdf) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to comply with the Publication Policy as set out in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to delete the Data transferred from the Data Producers, once it is no longer required to be used for the Project or after the agreed data retention period has expired (whichever comes first), unless obliged to retain the data for archival purposes in conformity with audit or legal requirements and all in accordance with the File Access Security policy as set out in Appendix I. 12. The User Institution will notify the Provider Institution within 30 days of any changes or departures of any Authorised Personnel. 13. The User Institution will notify the Provider Institution prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the Provider Institution as soon as it becomes aware of a breach of the terms or conditions of this Agreement. 15. The Provider Institution may terminate this agreement by written notice to the User Institution. If this Agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this Agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than the Provider Institution. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the Agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this Agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution hereby procures that the Authorised Personnel shall comply with the terms of this Agreement. 19. This Agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of Scotland and shall be subject to the exclusive jurisdiction of the Scottish courts. Agreed for and on behalf of the User Institution Name of User Institution: Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for and on behalf of the Provider Institution Signature: Name: Title: Edinburgh Research Office Authorised Signatory Date: APPENDIX I – DATASET DETAILS Dataset reference (EGA Study ID and Dataset Details) EGA STUDY ID DATASET DETAILS Name of project that created the dataset Names of other Data Producers/collaborators Specific limitations on areas of research Minimum protection measures required File Access Security: Only Authorised Personnel may have access to both the raw and any associated downstream processed filesets for the duration of the Project and these should not be shared with non-Authorised Personnel (see Appendix II). The Data shall be held in unencrypted files on a secure institutional compute system requiring user log in, with Unix user group read/write access for one or more appropriate groups (but not Unix world read/write access) behind a secure firewall. Laptops holding these data shall have password protected logins and screenlocks (set to lock after 5 min of inactivity). If held on USB keys or other portable hard drives, the data must be encrypted and only stored for the minimum length of time required (i.e. for data transfer). The raw datasets provided should be deleted from all file systems no longer than 12 months after the approval has been granted under the terms of this Data Access Agreement. This time period does not apply to any downstream processed data files which can be kept for the duration of the project. The Data shall at all times be used in accordance with the terms of EGA policy on the Implementation of the EU General Data Protection Regulation (GDPR) as set out at: https://ega-archive.org/about/privacy-notice APPENDIX II – PROJECT DETAILS Name of User Institution: (to be completed by the Requestor) Details of dataset requested i.e., EGA Study and Dataset Accession Number (to be completed by the Requestor) Brief abstract of the Project in which the Data will be used (500 words max) (to be completed by the Requestor) All Individuals who the User Institution seeks to be named as registered users Name of Registered User Email Job Title Supervisor (to be completed by the Requestor) All Individuals that should have an account created at the EGA Name of Registered User Email Job Title (to be completed by the Requestor) APPENDIX III – PUBLICATION POLICY The Provider Institution intend to publish the results of their analysis of this dataset and do not consider its deposition into public databases to be the equivalent of such publications. The Provider Institution anticipate that the dataset could be useful to other qualified researchers for a variety of purposes. However, some areas of work are subject to a publication moratorium. The publication moratorium covers any publications (including oral communications) that describe the use of the Data. The User Institution agrees to follow the publication criteria set out below: For research papers, submission for publication should not occur until six months after these data were first made available on the relevant hosting database, unless the Provider Institution has provided written consent to agree to an earlier submission. In any publications resulting from the Data provided here, the Data sets must be correctly referenced, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers (e.g., EGAS00000000029), and acknowledge its use in a form agreed by the User Institution with the Provider Institution. Any publication must cite the following acknowledgement: 'This publication would not have been possible without the support of the Institute of Genetics and Cancer at the University of Edinburgh, and the Nicola Murray Centre for Ovarian Cancer Research' Prior to publication, the User Institution shall check with the Data Producers to ensure that the most relevant publications, with respect to the Data, are cited in their work.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001008259 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00008887167 fastq.gz 2.2 GB
EGAF00008887168 fastq.gz 2.3 GB
EGAF00008887169 fastq.gz 2.4 GB
EGAF00008887170 fastq.gz 2.5 GB
EGAF00008887171 fastq.gz 2.1 GB
EGAF00008887172 fastq.gz 2.2 GB
EGAF00008887173 fastq.gz 1.2 GB
EGAF00008887174 fastq.gz 1.2 GB
EGAF00008887175 fastq.gz 1.2 GB
EGAF00008887176 fastq.gz 1.2 GB
EGAF00008887177 fastq.gz 1.2 GB
EGAF00008887178 fastq.gz 1.2 GB
EGAF00008887179 fastq.gz 1.3 GB
EGAF00008887180 fastq.gz 1.2 GB
EGAF00008887181 fastq.gz 2.6 GB
EGAF00008887182 fastq.gz 2.7 GB
EGAF00008887183 fastq.gz 1.3 GB
EGAF00008887184 fastq.gz 1.2 GB
EGAF00008887185 fastq.gz 1.3 GB
EGAF00008887186 fastq.gz 1.3 GB
EGAF00008887187 fastq.gz 1.3 GB
EGAF00008887188 fastq.gz 1.3 GB
EGAF00008887189 fastq.gz 1.3 GB
EGAF00008887190 fastq.gz 1.3 GB
EGAF00008887191 fastq.gz 2.0 GB
EGAF00008887192 fastq.gz 1.9 GB
EGAF00008887193 fastq.gz 627.7 MB
EGAF00008887194 fastq.gz 613.3 MB
EGAF00008887195 fastq.gz 641.8 MB
EGAF00008887196 fastq.gz 631.6 MB
EGAF00008887197 fastq.gz 636.1 MB
EGAF00008887198 fastq.gz 623.3 MB
EGAF00008887199 fastq.gz 650.4 MB
EGAF00008887200 fastq.gz 640.3 MB
EGAF00008887201 fastq.gz 3.0 GB
EGAF00008887202 fastq.gz 3.0 GB
EGAF00008887203 fastq.gz 3.6 GB
EGAF00008887204 fastq.gz 3.7 GB
EGAF00008887205 fastq.gz 2.0 GB
EGAF00008887206 fastq.gz 2.0 GB
EGAF00008887207 fastq.gz 683.5 MB
EGAF00008887208 fastq.gz 672.5 MB
EGAF00008887209 fastq.gz 651.3 MB
EGAF00008887210 fastq.gz 669.4 MB
EGAF00008887211 fastq.gz 694.9 MB
EGAF00008887212 fastq.gz 688.5 MB
EGAF00008887213 fastq.gz 666.6 MB
EGAF00008887214 fastq.gz 686.5 MB
EGAF00008887215 fastq.gz 2.9 GB
EGAF00008887216 fastq.gz 2.9 GB
EGAF00008887217 fastq.gz 2.6 GB
EGAF00008887218 fastq.gz 2.7 GB
EGAF00008887219 fastq.gz 2.6 GB
EGAF00008887220 fastq.gz 2.7 GB
EGAF00008887221 fastq.gz 742.1 MB
EGAF00008887222 fastq.gz 726.9 MB
EGAF00008887223 fastq.gz 707.9 MB
EGAF00008887224 fastq.gz 737.4 MB
EGAF00008887225 fastq.gz 743.5 MB
EGAF00008887226 fastq.gz 735.6 MB
EGAF00008887227 fastq.gz 716.3 MB
EGAF00008887228 fastq.gz 748.8 MB
EGAF00008887229 fastq.gz 2.0 GB
EGAF00008887230 fastq.gz 2.0 GB
EGAF00008887231 fastq.gz 2.3 GB
EGAF00008887232 fastq.gz 2.4 GB
EGAF00008887233 fastq.gz 2.2 GB
EGAF00008887234 fastq.gz 2.2 GB
EGAF00008887235 fastq.gz 555.1 MB
EGAF00008887236 fastq.gz 541.7 MB
EGAF00008887237 fastq.gz 555.5 MB
EGAF00008887238 fastq.gz 553.0 MB
EGAF00008887239 fastq.gz 567.6 MB
EGAF00008887240 fastq.gz 553.4 MB
EGAF00008887241 fastq.gz 566.3 MB
EGAF00008887242 fastq.gz 565.8 MB
EGAF00008887243 fastq.gz 3.6 GB
EGAF00008887244 fastq.gz 3.7 GB
EGAF00008887245 fastq.gz 774.9 MB
EGAF00008887246 fastq.gz 759.8 MB
EGAF00008887247 fastq.gz 743.5 MB
EGAF00008887248 fastq.gz 770.3 MB
EGAF00008887249 fastq.gz 777.9 MB
EGAF00008887250 fastq.gz 769.2 MB
EGAF00008887251 fastq.gz 751.8 MB
EGAF00008887252 fastq.gz 781.8 MB
EGAF00008887253 fastq.gz 3.6 GB
EGAF00008887254 fastq.gz 3.7 GB
EGAF00008887255 fastq.gz 841.9 MB
EGAF00008887256 fastq.gz 826.9 MB
EGAF00008887257 fastq.gz 795.6 MB
EGAF00008887258 fastq.gz 826.4 MB
EGAF00008887259 fastq.gz 844.3 MB
EGAF00008887260 fastq.gz 831.2 MB
EGAF00008887261 fastq.gz 802.0 MB
EGAF00008887262 fastq.gz 834.1 MB
EGAF00008887263 fastq.gz 2.9 GB
EGAF00008887264 fastq.gz 3.0 GB
EGAF00008887265 fastq.gz 4.8 GB
EGAF00008887266 fastq.gz 4.9 GB
EGAF00008887267 fastq.gz 4.5 GB
EGAF00008887268 fastq.gz 4.6 GB
EGAF00008887269 fastq.gz 676.4 MB
EGAF00008887270 fastq.gz 657.1 MB
EGAF00008887271 fastq.gz 650.1 MB
EGAF00008887272 fastq.gz 668.4 MB
EGAF00008887273 fastq.gz 690.8 MB
EGAF00008887274 fastq.gz 678.3 MB
EGAF00008887275 fastq.gz 670.4 MB
EGAF00008887276 fastq.gz 690.3 MB
EGAF00008887277 fastq.gz 1.6 GB
EGAF00008887278 fastq.gz 1.6 GB
EGAF00008887279 fastq.gz 1.9 GB
EGAF00008887280 fastq.gz 2.0 GB
EGAF00008887281 fastq.gz 2.9 GB
EGAF00008887282 fastq.gz 3.0 GB
EGAF00008887283 fastq.gz 3.2 GB
EGAF00008887284 fastq.gz 3.3 GB
EGAF00008887285 fastq.gz 4.4 GB
EGAF00008887286 fastq.gz 4.4 GB
EGAF00008887287 fastq.gz 3.0 GB
EGAF00008887288 fastq.gz 3.1 GB
EGAF00008887289 fastq.gz 3.5 GB
EGAF00008887290 fastq.gz 3.6 GB
EGAF00008887291 fastq.gz 966.1 MB
EGAF00008887292 fastq.gz 933.0 MB
EGAF00008887293 fastq.gz 922.8 MB
EGAF00008887294 fastq.gz 945.5 MB
EGAF00008887295 fastq.gz 973.4 MB
EGAF00008887296 fastq.gz 944.4 MB
EGAF00008887297 fastq.gz 932.9 MB
EGAF00008887298 fastq.gz 957.2 MB
EGAF00008887299 fastq.gz 3.3 GB
EGAF00008887300 fastq.gz 3.3 GB
EGAF00008887301 fastq.gz 2.7 GB
EGAF00008887302 fastq.gz 2.7 GB
EGAF00008887303 fastq.gz 3.6 GB
EGAF00008887304 fastq.gz 3.6 GB
EGAF00008887305 fastq.gz 4.9 GB
EGAF00008887306 fastq.gz 5.0 GB
EGAF00008887307 fastq.gz 2.8 GB
EGAF00008887308 fastq.gz 2.9 GB
EGAF00008887309 fastq.gz 2.5 GB
EGAF00008887310 fastq.gz 2.6 GB
EGAF00008887311 fastq.gz 4.2 GB
EGAF00008887312 fastq.gz 4.3 GB
EGAF00008887313 fastq.gz 5.6 GB
EGAF00008887314 fastq.gz 5.6 GB
EGAF00008887315 fastq.gz 2.7 GB
EGAF00008887316 fastq.gz 2.7 GB
EGAF00008887317 fastq.gz 3.7 GB
EGAF00008887318 fastq.gz 3.7 GB
EGAF00008887319 fastq.gz 3.2 GB
EGAF00008887320 fastq.gz 3.2 GB
EGAF00008887321 fastq.gz 2.8 GB
EGAF00008887322 fastq.gz 2.8 GB
EGAF00008887323 fastq.gz 5.5 GB
EGAF00008887324 fastq.gz 5.5 GB
EGAF00008887325 fastq.gz 726.0 MB
EGAF00008887326 fastq.gz 714.8 MB
EGAF00008887327 fastq.gz 683.9 MB
EGAF00008887328 fastq.gz 712.8 MB
EGAF00008887329 fastq.gz 732.0 MB
EGAF00008887330 fastq.gz 724.6 MB
EGAF00008887331 fastq.gz 695.9 MB
EGAF00008887332 fastq.gz 725.6 MB
EGAF00008887333 fastq.gz 8.1 GB
EGAF00008887334 fastq.gz 8.1 GB
EGAF00008887335 fastq.gz 7.3 GB
EGAF00008887336 fastq.gz 7.4 GB
EGAF00008887337 fastq.gz 10.2 GB
EGAF00008887338 fastq.gz 10.2 GB
EGAF00008887339 fastq.gz 12.5 GB
EGAF00008887340 fastq.gz 12.6 GB
174 Files (394.2 GB)