About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Whole genome sequencing of tumor samples from advanced pre-treated NSCLC patients recruited in a phase I/II single-arm trial utilising CVA21, an oncolytic coxsackie virus, in combination with pembrolizumab.

This dataset contains paired tumor and matched normal whole-genome sequencing (WGS) data from longitudinally collected samples of patients enrolled in an Australian clinical study involving multiple cancer types. For each patient, one or more tumor biopsies were obtained at different treatment time points (Scr, Day 0, Day 15, Day 22, Day 33), and matched normal samples were collected either from blood or non-tumor tissue.

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WEHI Data Access Committee data access policy

1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. 3. The User Institution agrees to protect the confidentiality and privacy of Research Participants in any research papers or publications that they prepare by using their best efforts to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the User Institution that may arise (whether directly or indirectly) in any way whatsoever from the User Institution’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Authorship guide and the Toronto Statement. This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research relating to the Data. 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify WEHI within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify WEHI prior to any significant changes to the protocol for the Project. 14. The User Institution will notify WEHI as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. WEHI may terminate this agreement by written notice to the User Institution at any time and for any reason or no reason. If this agreement is terminated, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than WEHI. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected by WEHI or its delegate to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of Victoria, Australia, and shall be subject to the exclusive jurisdiction of the Victorian courts. 20. The User Institution agrees that its rights and obligations hereunder are not assignable. 21. This agreement does not constitute any party the agent of another or imply that the parties intend constituting a partnership, joint venture or other form of association in which any party may be liable for the acts or omissions of the other.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001008258 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF00008887483 fastq.gz 22.4 GB
EGAF00008887484 fastq.gz 24.3 GB
EGAF00008887485 fastq.gz 22.7 GB
EGAF00008887486 fastq.gz 24.4 GB
EGAF00008887487 fastq.gz 28.4 GB
EGAF00008887488 fastq.gz 33.7 GB
EGAF00008887489 fastq.gz 9.5 GB
EGAF00008887490 fastq.gz 10.7 GB
EGAF00008887491 fastq.gz 49.0 GB
EGAF00008887492 fastq.gz 54.5 GB
EGAF00008887493 fastq.gz 40.2 GB
EGAF00008887494 fastq.gz 45.8 GB
EGAF00008887495 fastq.gz 42.7 GB
EGAF00008887496 fastq.gz 47.9 GB
EGAF00008887497 fastq.gz 21.9 GB
EGAF00008887498 fastq.gz 23.4 GB
EGAF00008887499 fastq.gz 21.9 GB
EGAF00008887500 fastq.gz 23.2 GB
EGAF00008887501 fastq.gz 30.6 GB
EGAF00008887502 fastq.gz 32.9 GB
EGAF00008887503 fastq.gz 18.4 GB
EGAF00008887504 fastq.gz 20.9 GB
EGAF00008887505 fastq.gz 13.0 GB
EGAF00008887506 fastq.gz 14.3 GB
EGAF00008887507 fastq.gz 13.0 GB
EGAF00008887508 fastq.gz 14.6 GB
EGAF00008887509 fastq.gz 13.0 GB
EGAF00008887510 fastq.gz 14.4 GB
EGAF00008887511 fastq.gz 45.4 GB
EGAF00008887512 fastq.gz 52.3 GB
EGAF00008887513 fastq.gz 44.8 GB
EGAF00008887514 fastq.gz 48.2 GB
EGAF00008887515 fastq.gz 45.3 GB
EGAF00008887516 fastq.gz 48.1 GB
EGAF00008887517 fastq.gz 37.3 GB
EGAF00008887518 fastq.gz 40.0 GB
EGAF00008887519 fastq.gz 37.3 GB
EGAF00008887520 fastq.gz 40.2 GB
EGAF00008887521 fastq.gz 39.2 GB
EGAF00008887522 fastq.gz 42.2 GB
EGAF00008887523 fastq.gz 39.2 GB
EGAF00008887524 fastq.gz 42.3 GB
EGAF00008887525 fastq.gz 16.9 GB
EGAF00008887526 fastq.gz 18.2 GB
EGAF00008887527 fastq.gz 16.9 GB
EGAF00008887528 fastq.gz 18.3 GB
EGAF00008887529 fastq.gz 43.0 GB
EGAF00008887530 fastq.gz 48.0 GB
EGAF00008887531 fastq.gz 88.6 GB
EGAF00008887532 fastq.gz 96.3 GB
EGAF00008887533 fastq.gz 66.1 GB
EGAF00008887534 fastq.gz 69.6 GB
EGAF00008887535 fastq.gz 35.5 GB
EGAF00008887536 fastq.gz 38.2 GB
EGAF00008887537 fastq.gz 36.1 GB
EGAF00008887538 fastq.gz 38.5 GB
EGAF00008887539 fastq.gz 34.3 GB
EGAF00008887540 fastq.gz 37.0 GB
EGAF00008887541 fastq.gz 34.7 GB
EGAF00008887542 fastq.gz 37.1 GB
EGAF00008887543 fastq.gz 39.3 GB
EGAF00008887544 fastq.gz 42.1 GB
EGAF00008887545 fastq.gz 39.3 GB
EGAF00008887546 fastq.gz 41.7 GB
EGAF00008887547 fastq.gz 44.3 GB
EGAF00008887548 fastq.gz 47.6 GB
EGAF00008887549 fastq.gz 44.3 GB
EGAF00008887550 fastq.gz 47.2 GB
EGAF00008887551 fastq.gz 93.2 GB
EGAF00008887552 fastq.gz 100.3 GB
EGAF00008887553 fastq.gz 26.4 GB
EGAF00008887554 fastq.gz 28.6 GB
EGAF00008887555 fastq.gz 26.3 GB
EGAF00008887556 fastq.gz 29.2 GB
EGAF00008887557 fastq.gz 26.4 GB
EGAF00008887558 fastq.gz 28.8 GB
EGAF00008887559 fastq.gz 26.1 GB
EGAF00008887560 fastq.gz 28.0 GB
EGAF00008887561 fastq.gz 26.1 GB
EGAF00008887562 fastq.gz 28.6 GB
EGAF00008887563 fastq.gz 25.9 GB
EGAF00008887564 fastq.gz 28.1 GB
EGAF00008887565 fastq.gz 31.9 GB
EGAF00008887566 fastq.gz 34.8 GB
EGAF00008887567 fastq.gz 31.9 GB
EGAF00008887568 fastq.gz 35.4 GB
EGAF00008887569 fastq.gz 31.6 GB
EGAF00008887570 fastq.gz 34.7 GB
EGAF00008887571 fastq.gz 25.4 GB
EGAF00008887572 fastq.gz 27.7 GB
EGAF00008887573 fastq.gz 25.6 GB
EGAF00008887574 fastq.gz 28.6 GB
EGAF00008887575 fastq.gz 25.3 GB
EGAF00008887576 fastq.gz 27.9 GB
EGAF00008887577 fastq.gz 27.1 GB
EGAF00008887578 fastq.gz 29.3 GB
EGAF00008887579 fastq.gz 27.2 GB
EGAF00008887580 fastq.gz 29.9 GB
EGAF00008887581 fastq.gz 26.8 GB
EGAF00008887582 fastq.gz 29.2 GB
EGAF00008887583 fastq.gz 23.6 GB
EGAF00008887584 fastq.gz 25.8 GB
EGAF00008887585 fastq.gz 23.6 GB
EGAF00008887586 fastq.gz 26.3 GB
EGAF00008887587 fastq.gz 23.5 GB
EGAF00008887588 fastq.gz 25.9 GB
EGAF00008887589 fastq.gz 22.6 GB
EGAF00008887590 fastq.gz 24.6 GB
EGAF00008887591 fastq.gz 22.5 GB
EGAF00008887592 fastq.gz 25.1 GB
EGAF00008887593 fastq.gz 22.5 GB
EGAF00008887594 fastq.gz 24.7 GB
112 Files (3.8 TB)