Acral Melanoma PDXs from the admixed Brazilian Population - Tumour and unfiltered PDX sample CRAM files - RNAseq
Patient Derived Xenograft RNAseq sample CRAM files mapped to build GRCh38. Acral melanoma (AM) is an aggressive melanoma subtype with limited therapeutic options and poor outcomes. In non-European descent and admixed populations, like in Latin America, it can account for a significant proportion of cutaneous melanoma cases. Here, we performed comprehensive genomic and functional profiling of AM from a uniquely diverse Brazilian cohort. Whole-exome and transcriptome sequencing was performed on both tumours and patient-derived xenograft (PDX) samples. The PDX were obtained from a comprehensive collection of patient-derived xenograft (AM-PDX) models that we established which faithfully retained the histopathological and genomic features of the original tumours.
- 15/10/2025
- 1 sample
- DAC: EGAC00001000205
- Technology: Illumina NovaSeq 6000
Wellcome Trust Sanger Institute Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001008150 | Transcriptome Analysis |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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|---|---|---|---|---|
| EGAF00008888853 | cram | 3.0 GB |
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| EGAF00008888854 | cram | 2.3 GB |
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| EGAF00008888855 | cram | 2.3 GB |
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| EGAF00008888856 | cram | 2.3 GB |
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| EGAF00008888857 | cram | 2.5 GB |
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| EGAF00008888858 | cram | 2.7 GB |
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| EGAF00008888859 | cram | 3.0 GB |
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| EGAF00008888860 | cram | 3.3 GB |
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| EGAF00008888861 | cram | 2.5 GB |
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| EGAF00008888862 | cram | 2.4 GB |
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| EGAF00008888863 | cram | 2.2 GB |
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| EGAF00008888864 | cram | 2.8 GB |
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| EGAF00008888865 | cram | 2.6 GB |
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| EGAF00008888866 | cram | 1.8 GB |
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| EGAF00008888867 | cram | 2.0 GB |
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| EGAF00008888868 | cram | 2.9 GB |
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| EGAF00008888869 | cram | 2.5 GB |
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| EGAF00008888870 | cram | 2.0 GB |
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| EGAF00008888871 | cram | 2.2 GB |
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| EGAF00008888872 | cram | 2.4 GB |
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| EGAF00008888873 | cram | 2.1 GB |
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| EGAF00008888874 | cram | 2.0 GB |
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| EGAF00008888875 | cram | 2.6 GB |
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| EGAF00008888876 | cram | 2.9 GB |
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| EGAF00008888877 | cram | 1.1 GB |
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| EGAF00008888878 | cram | 2.6 GB |
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| EGAF00008888879 | cram | 2.8 GB |
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| EGAF00008888880 | cram | 1.3 GB |
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| EGAF00008888881 | cram | 1.1 GB |
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| EGAF00008888882 | cram | 2.2 GB |
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| EGAF00008888883 | cram | 2.2 GB |
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| EGAF00008888884 | cram | 2.0 GB |
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| EGAF00008888885 | cram | 2.7 GB |
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| EGAF00008888886 | cram | 2.6 GB |
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| EGAF00008888887 | cram | 2.4 GB |
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| EGAF00008888888 | cram | 2.3 GB |
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| EGAF00008888889 | cram | 1.3 GB |
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| EGAF00008888890 | cram | 2.3 GB |
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| EGAF00008888891 | cram | 2.2 GB |
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| EGAF00008888892 | cram | 2.5 GB |
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| EGAF00008888893 | cram | 1.7 GB |
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| EGAF00008888894 | cram | 2.2 GB |
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| EGAF00008888895 | cram | 2.8 GB |
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| EGAF00008888896 | cram | 2.0 GB |
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| EGAF00008888897 | cram | 2.4 GB |
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| EGAF00008888898 | cram | 1.7 GB |
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| EGAF00008888899 | cram | 1.7 GB |
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| EGAF00008888900 | cram | 2.2 GB |
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| EGAF00008888901 | cram | 2.6 GB |
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| EGAF00008888902 | cram | 2.0 GB |
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| EGAF00008888903 | cram | 1.8 GB |
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| EGAF00008888904 | cram | 2.6 GB |
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| EGAF00008888905 | cram | 2.3 GB |
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| EGAF00008888906 | cram | 2.2 GB |
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| EGAF00008888907 | cram | 1.8 GB |
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| EGAF00008888908 | cram | 2.6 GB |
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| EGAF00008888909 | cram | 1.4 GB |
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| EGAF00008888910 | cram | 2.6 GB |
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| EGAF00008888911 | cram | 1.9 GB |
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| EGAF00008888912 | cram | 2.5 GB |
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| EGAF00008888913 | cram | 2.5 GB |
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| EGAF00008888914 | cram | 2.6 GB |
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| EGAF00008888915 | cram | 2.4 GB |
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| EGAF00008888916 | cram | 2.8 GB |
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| EGAF00008888917 | cram | 2.8 GB |
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| EGAF00008888918 | cram | 2.9 GB |
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| 66 Files (151.9 GB) | ||||