Ribo-Seq dataset of Targeting the dark proteome to expand the lineage-retained antigen landscape in neuroblastoma
This dataset contains ribosome profiling (Ribo-seq) data generated to map actively translated open reading frames, including non-canonical ORFs from the "dark proteome", in neuroblastoma, supporting the identification of translation-validated tumor antigens. Ribosome-protected mRNA fragments (~28–30 nt) were isolated from 47 neuroblastoma samples comprising cell lines, patient-derived tumoroids, and primary patient tumors spanning the adrenergic (ADRN) and mesenchymal (MES) lineage states. Libraries were prepared following a modified version of the McGlincy & Ingolia 2017 protocol and sequenced single-end (1x50 bp) on the Illumina NextSeq 2000 platform. Raw data are provided as single-end fastq.gz
- 04/05/2026
- 47 samples
- DAC: EGAC00001001864
- Technologies: Illumina NovaSeq 6000, NextSeq 2000
DUO:0000007 version: 2021-02-23
disease specific research
This data use permission indicates that use is allowed provided it is related to the specified disease.
ModifiersMONDO_0006517
Data Access Agreement of data controlled by the Data Access Commitee of the Princess Maxima Center for Pediatric Oncology
The Princess Maxima Center for pediatric oncology default access policy to enable re-production of research and re-use of data for scientific purposes. Please contact the DAC (EGAC00001001864) for the most up to date policies.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001008445 | Other |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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| EGAF00009042002 | fastq.gz | 359.2 MB |
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| EGAF00009042003 | fastq.gz | 1.1 GB |
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| EGAF00009042004 | fastq.gz | 1.0 GB |
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| EGAF00009042005 | fastq.gz | 1.4 GB |
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| EGAF00009042006 | fastq.gz | 1.9 GB |
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| EGAF00009042007 | fastq.gz | 1.3 GB |
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| EGAF00009042008 | fastq.gz | 1.4 GB |
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| EGAF00009042009 | fastq.gz | 1.2 GB |
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| EGAF00009042010 | fastq.gz | 1.4 GB |
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| EGAF00009042011 | fastq.gz | 1.4 GB |
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| EGAF00009042012 | fastq.gz | 1.5 GB |
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| EGAF00009042013 | fastq.gz | 1.3 GB |
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| EGAF00009042014 | fastq.gz | 1.5 GB |
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| EGAF00009042015 | fastq.gz | 1.5 GB |
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| EGAF00009042016 | fastq.gz | 2.0 GB |
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| EGAF00009042017 | fastq.gz | 1.3 GB |
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| EGAF00009042018 | fastq.gz | 831.9 MB |
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| EGAF00009042019 | fastq.gz | 1.2 GB |
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| EGAF00009042020 | fastq.gz | 3.8 GB |
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| EGAF00009042021 | fastq.gz | 1.2 GB |
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| EGAF00009042022 | fastq.gz | 1.2 GB |
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| EGAF00009042023 | fastq.gz | 1.0 GB |
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| EGAF00009042024 | fastq.gz | 1.1 GB |
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| EGAF00009042025 | fastq.gz | 4.8 GB |
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| EGAF00009042026 | fastq.gz | 4.0 GB |
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| EGAF00009042027 | fastq.gz | 4.4 GB |
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| EGAF00009042028 | fastq.gz | 4.3 GB |
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| EGAF00009042029 | fastq.gz | 5.3 GB |
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| EGAF00009042030 | fastq.gz | 1.1 GB |
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| EGAF00009042031 | fastq.gz | 5.8 GB |
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| EGAF00009042032 | fastq.gz | 5.8 GB |
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| EGAF00009042033 | fastq.gz | 1.3 GB |
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| EGAF00009042035 | fastq.gz | 5.1 GB |
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| EGAF00009042036 | fastq.gz | 897.1 MB |
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| EGAF00009042038 | fastq.gz | 6.3 GB |
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| EGAF00009042039 | fastq.gz | 4.3 GB |
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| EGAF00009042040 | fastq.gz | 884.0 MB |
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| EGAF00009042041 | fastq.gz | 2.5 GB |
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| EGAF00009042042 | fastq.gz | 852.9 MB |
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| EGAF00009042044 | fastq.gz | 918.2 MB |
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| EGAF00009042045 | fastq.gz | 4.5 GB |
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| EGAF00009042046 | fastq.gz | 853.9 MB |
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| EGAF00009042051 | fastq.gz | 1.3 GB |
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| EGAF00009042055 | fastq.gz | 10.1 GB |
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| EGAF00009042059 | fastq.gz | 12.7 GB |
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| EGAF00009042063 | fastq.gz | 4.8 GB |
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| EGAF00009042069 | fastq.gz | 1.2 GB |
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| 47 Files (126.0 GB) | ||||
