Paediatric MN1::ZNF341-associated cancer scRNA-seq
A lethal round-cell malignancy with an MN1::ZNF341 fusion has recently been reported. Here, using single-cell RNA sequencing data derived from monozygotic twins, we find the tumour to be transcriptionally distinct from neuroblastoma. Instead, it exhibits steroidogenic differentiation. These data, in combination with the clinical, radiological, histopathological and additional molecular findings, corroborate suggestions that this tumour is a distinct and aggressive childhood cancer.
- 17/07/2026
- 1 sample
- DAC: EGAC00001000205
- Technology: Illumina NovaSeq 6000
- Archive: European Genome-phenome Archive (EGA)
Wellcome Trust Sanger Institute Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001003445 | Transcriptome Analysis |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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| EGAF00008901583 | cram | 16.2 GB |
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| EGAF00008901584 | cram | 15.3 GB |
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| EGAF00008901585 | cram | 15.0 GB |
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| EGAF00008903543 | cram | 20.2 GB |
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| EGAF00008903544 | cram | 21.2 GB |
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| EGAF00008903545 | cram | 22.6 GB |
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| 6 Files (110.5 GB) | ||||