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RNA-seq dataset of Dynamic APOBEC3A-associated mutagenesis shapes the genomic landscape of ETV6::RUNX1-positive B-cell precursor acute lymphoblastic leukemia

RNA sequencing was performed on Illumina Novaseq 6000 to generate 150 base-pair paired-end reads of 57 ETV6::RUNX1-positive BCP-ALL samples, aiming for 30M unique reads per sample. CRAMs were generated by read mapping to human reference genome hg38 using STAR-Fusion. The CRAMs were used to quantify the reference transcriptome using featureCounts from Rsubread.

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DUO:0000007
version: 2021-02-23

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO_0006517

Data Access Agreement of data controlled by the Data Access Commitee of the Princess Maxima Center for Pediatric Oncology

The Princess Maxima Center for pediatric oncology default access policy to enable re-production of research and re-use of data for scientific purposes. Please contact the DAC (EGAC00001001864) for the most up to date policies.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001008419 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00009220165 cram 5.2 GB
EGAF00009220167 cram 5.3 GB
EGAF00009220169 cram 6.4 GB
EGAF00009220171 cram 5.7 GB
EGAF00009220173 cram 8.4 GB
EGAF00009220174 cram 6.7 GB
EGAF00009220177 cram 5.5 GB
EGAF00009220179 cram 6.2 GB
EGAF00009220182 cram 5.5 GB
EGAF00009220184 cram 6.5 GB
EGAF00009220190 cram 7.6 GB
EGAF00009220193 cram 6.2 GB
EGAF00009220199 cram 3.8 GB
EGAF00009220200 cram 8.9 GB
EGAF00009220204 cram 3.8 GB
EGAF00009220218 cram 5.7 GB
EGAF00009220237 cram 3.9 GB
EGAF00009220239 cram 6.3 GB
EGAF00009220275 cram 7.8 GB
EGAF00009220348 cram 4.3 GB
EGAF00009220349 cram 4.6 GB
EGAF00009220350 cram 3.9 GB
EGAF00009220351 cram 5.6 GB
EGAF00009220352 cram 5.0 GB
EGAF00009220353 cram 8.6 GB
EGAF00009220354 cram 7.2 GB
EGAF00009220355 cram 8.8 GB
EGAF00009220356 cram 7.2 GB
EGAF00009220357 cram 7.2 GB
EGAF00009220358 cram 8.2 GB
EGAF00009220359 cram 6.3 GB
EGAF00009220360 cram 8.4 GB
EGAF00009220361 cram 6.7 GB
EGAF00009220362 cram 4.4 GB
EGAF00009220363 cram 5.5 GB
EGAF00009220365 cram 4.6 GB
EGAF00009220366 cram 5.1 GB
EGAF00009220367 cram 9.4 GB
EGAF00009220369 cram 5.0 GB
EGAF00009222528 cram 4.5 GB
EGAF00009222529 cram 4.4 GB
EGAF00009222530 cram 6.2 GB
EGAF00009222531 cram 5.1 GB
EGAF00009222532 cram 6.0 GB
EGAF00009222533 cram 5.8 GB
EGAF00009222534 cram 5.3 GB
EGAF00009222535 cram 9.2 GB
EGAF00009222536 cram 8.6 GB
EGAF00009222537 cram 7.5 GB
EGAF00009222538 cram 9.9 GB
EGAF00009222539 cram 4.8 GB
EGAF00009222540 cram 6.5 GB
EGAF00009222541 cram 8.7 GB
EGAF00009222543 cram 5.7 GB
EGAF00009222545 cram 5.1 GB
EGAF00009222548 cram 8.4 GB
EGAF00009222549 cram 5.0 GB
57 Files (358.2 GB)