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ONGOING CHROMOSOMAL INSTABILITY ACROSS ANEUPLOID SUBTYPES OF CHILDHOOD B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA ASSOCIATES WITH DISEASE PROGRESSION

Single-cells from primary cB-ALL samples were isolated using an inverted microscope coupled to a micromanipulator equipped with glass capillary for cell collection. A minimum of 20 cells were isolated per sample in microdrops of 2.5 μl of phosphate buffered saline (PBS) with 0.5% polyvinylpyrrolidone. Cell lysis and DNA amplification was performed using the SurePlex DNA Amplification System (Illumina). Genomic DNA was subsequently fragmented and tagged with the VeriSeq PGS transposome and the TruSeq Index adapters by PCR for library preparation (VeriSeq PGS Library Prep Kit, Illumina). Equal volumes of normalized libraries were pooled and sequenced on an Illumina MySeq platform with 1×75-bp single-end sequencing. Reads were subsequently aligned to the human reference genome (GRCh38/hg38) using Bowtie2 (version 2.2.4).

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DAC

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000019 Whole Genome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000047787 bam 83.7 MB
EGAF50000047788 bam 75.4 MB
EGAF50000047789 bam 67.8 MB
EGAF50000047790 bam 66.2 MB
EGAF50000047791 bam 52.6 MB
EGAF50000047792 bam 77.8 MB
EGAF50000047793 bam 77.4 MB
EGAF50000047794 bam 59.6 MB
EGAF50000047795 bam 58.8 MB
EGAF50000047796 bam 85.5 MB
EGAF50000047797 bam 81.5 MB
EGAF50000047798 bam 61.1 MB
EGAF50000047799 bam 71.8 MB
EGAF50000047800 bam 84.8 MB
EGAF50000047801 bam 74.1 MB
EGAF50000047802 bam 68.1 MB
EGAF50000047803 bam 73.6 MB
EGAF50000047804 bam 79.1 MB
EGAF50000047805 bam 85.5 MB
EGAF50000047806 bam 71.1 MB
EGAF50000047807 bam 25.4 MB
EGAF50000047808 bam 28.2 MB
EGAF50000047809 bam 20.9 MB
EGAF50000047810 bam 13.6 MB
EGAF50000047811 bam 25.9 MB
EGAF50000047812 bam 11.3 MB
EGAF50000047813 bam 29.3 MB
EGAF50000047814 bam 70.8 MB
EGAF50000047815 bam 24.2 MB
EGAF50000047816 bam 21.6 MB
EGAF50000047817 bam 26.3 MB
EGAF50000047818 bam 23.8 MB
EGAF50000047819 bam 29.4 MB
EGAF50000047820 bam 25.5 MB
EGAF50000047821 bam 27.0 MB
EGAF50000047822 bam 30.0 MB
EGAF50000047823 bam 29.7 MB
EGAF50000047824 bam 23.4 MB
EGAF50000047825 bam 27.8 MB
EGAF50000047826 bam 21.7 MB
EGAF50000047827 bam 19.4 MB
EGAF50000047828 bam 22.8 MB
EGAF50000047829 bam 24.5 MB
EGAF50000047830 bam 22.6 MB
EGAF50000047831 bam 26.4 MB
EGAF50000047832 bam 27.4 MB
EGAF50000047833 bam 29.9 MB
EGAF50000047834 bam 31.1 MB
EGAF50000047835 bam 22.7 MB
EGAF50000047836 bam 25.6 MB
EGAF50000047837 bam 26.3 MB
EGAF50000047838 bam 28.8 MB
EGAF50000047839 bam 26.1 MB
EGAF50000047840 bam 26.8 MB
EGAF50000047841 bam 23.2 MB
EGAF50000047842 bam 25.0 MB
EGAF50000047843 bam 27.3 MB
EGAF50000047844 bam 24.5 MB
EGAF50000047845 bam 26.3 MB
EGAF50000047846 bam 23.3 MB
EGAF50000047847 bam 26.0 MB
EGAF50000047848 bam 20.3 MB
EGAF50000047849 bam 24.1 MB
EGAF50000047850 bam 25.9 MB
EGAF50000047851 bam 22.3 MB
EGAF50000047852 bam 28.9 MB
EGAF50000047853 bam 26.5 MB
EGAF50000047854 bam 27.6 MB
EGAF50000047855 bam 25.2 MB
EGAF50000047856 bam 24.4 MB
EGAF50000047857 bam 20.6 MB
EGAF50000047858 bam 29.5 MB
EGAF50000047859 bam 25.6 MB
EGAF50000047860 bam 24.7 MB
EGAF50000047861 bam 28.5 MB
EGAF50000047862 bam 26.5 MB
EGAF50000047863 bam 29.4 MB
EGAF50000047864 bam 28.1 MB
EGAF50000047865 bam 30.1 MB
EGAF50000047866 bam 31.7 MB
EGAF50000047867 bam 21.6 MB
EGAF50000047868 bam 18.9 MB
EGAF50000047869 bam 22.7 MB
EGAF50000047870 bam 19.4 MB
EGAF50000047871 bam 19.2 MB
EGAF50000047872 bam 21.9 MB
EGAF50000047873 bam 22.6 MB
EGAF50000047874 bam 11.7 MB
EGAF50000047875 bam 22.9 MB
EGAF50000047876 bam 18.9 MB
EGAF50000047877 bam 21.8 MB
EGAF50000047878 bam 22.5 MB
EGAF50000047879 bam 27.8 MB
EGAF50000047880 bam 26.6 MB
EGAF50000047881 bam 25.9 MB
EGAF50000047882 bam 24.6 MB
EGAF50000047883 bam 27.4 MB
EGAF50000047884 bam 24.1 MB
EGAF50000047885 bam 23.8 MB
EGAF50000047886 bam 26.5 MB
EGAF50000047887 bam 25.9 MB
EGAF50000047888 bam 23.0 MB
EGAF50000047889 bam 19.2 MB
EGAF50000047890 bam 20.0 MB
EGAF50000047891 bam 22.2 MB
EGAF50000047892 bam 24.1 MB
EGAF50000047893 bam 22.8 MB
EGAF50000047894 bam 29.2 MB
EGAF50000047895 bam 23.5 MB
EGAF50000047896 bam 18.1 MB
EGAF50000047897 bam 28.8 MB
EGAF50000047898 bam 27.1 MB
EGAF50000047899 bam 28.5 MB
EGAF50000047900 bam 26.5 MB
EGAF50000047901 bam 28.3 MB
EGAF50000047902 bam 27.1 MB
EGAF50000047903 bam 27.8 MB
EGAF50000047904 bam 29.5 MB
EGAF50000047905 bam 34.2 MB
EGAF50000047906 bam 17.6 MB
EGAF50000047907 bam 34.1 MB
EGAF50000047908 bam 30.5 MB
EGAF50000047909 bam 35.7 MB
EGAF50000047910 bam 29.4 MB
EGAF50000047911 bam 31.3 MB
EGAF50000047912 bam 31.3 MB
EGAF50000047913 bam 32.1 MB
EGAF50000047914 bam 33.6 MB
EGAF50000047915 bam 24.9 MB
EGAF50000047916 bam 17.3 MB
EGAF50000047917 bam 31.4 MB
EGAF50000047918 bam 28.4 MB
EGAF50000047919 bam 24.6 MB
EGAF50000047920 bam 25.6 MB
EGAF50000047921 bam 23.0 MB
EGAF50000047922 bam 29.0 MB
EGAF50000047923 bam 19.9 MB
EGAF50000047924 bam 23.5 MB
EGAF50000047925 bam 19.5 MB
EGAF50000047926 bam 20.6 MB
EGAF50000047927 bam 23.1 MB
EGAF50000047928 bam 23.2 MB
EGAF50000047929 bam 20.7 MB
EGAF50000047930 bam 21.4 MB
EGAF50000047931 bam 19.3 MB
EGAF50000047932 bam 22.3 MB
EGAF50000047933 bam 17.1 MB
EGAF50000047934 bam 17.4 MB
EGAF50000047935 bam 21.0 MB
EGAF50000047936 bam 12.8 MB
EGAF50000047937 bam 20.5 MB
EGAF50000047938 bam 14.1 MB
EGAF50000047939 bam 14.2 MB
EGAF50000047940 bam 17.7 MB
EGAF50000047941 bam 20.0 MB
EGAF50000047942 bam 15.3 MB
EGAF50000047943 bam 13.0 MB
EGAF50000047944 bam 20.9 MB
EGAF50000047945 bam 11.8 MB
EGAF50000047946 bam 22.3 MB
EGAF50000047947 bam 17.9 MB
EGAF50000047948 bam 21.9 MB
EGAF50000047949 bam 15.7 MB
EGAF50000047950 bam 16.2 MB
EGAF50000047951 bam 19.6 MB
EGAF50000047952 bam 19.8 MB
EGAF50000047953 bam 19.3 MB
EGAF50000047954 bam 19.1 MB
EGAF50000047955 bam 19.2 MB
EGAF50000047956 bam 17.7 MB
EGAF50000047957 bam 21.7 MB
EGAF50000047958 bam 18.0 MB
EGAF50000047959 bam 67.9 MB
EGAF50000047960 bam 17.7 MB
EGAF50000047961 bam 22.2 MB
EGAF50000047962 bam 20.8 MB
176 Files (5.3 GB)