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Targeted sequencing (paired) of HR genes in primary and metastatic patient-derived xenografts (PDXs) of colorectal cancer (CRC)

The dataset includes DNA targeted paired-wise (2 FASTQ per sample) sequencing of a manually curated panel of 44 genes with a documented role in homologous recombination (HR), a pathway of DNA damage response. Sequencing was conducted in 69 tumors from patients with metastatic colorectal cancer after serial passaging in mice (patient-derived xenografts, PDXs). For each PDX model profiled for HR gene mutations, therapeutic annotation of response to FOLFIRI (a chemotherapeutic regimen consisting of the combination of 5-fluorouracil and irinotecan) is available.

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General policy for IRCC datasets

Translational Cancer Medicine laboratory of Candiolo IRCC institute. Dataset available on request

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000075 Exome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000056491 fastq.gz 127.5 MB
EGAF50000056492 fastq.gz 131.9 MB
EGAF50000056493 fastq.gz 125.4 MB
EGAF50000056494 fastq.gz 125.2 MB
EGAF50000056495 fastq.gz 98.0 MB
EGAF50000056496 fastq.gz 96.5 MB
EGAF50000056497 fastq.gz 77.0 MB
EGAF50000056498 fastq.gz 75.8 MB
EGAF50000056499 fastq.gz 83.8 MB
EGAF50000056500 fastq.gz 85.8 MB
EGAF50000056501 fastq.gz 124.4 MB
EGAF50000056502 fastq.gz 122.3 MB
EGAF50000056503 fastq.gz 127.9 MB
EGAF50000056504 fastq.gz 126.0 MB
EGAF50000056505 fastq.gz 142.6 MB
EGAF50000056506 fastq.gz 137.3 MB
EGAF50000056507 fastq.gz 97.4 MB
EGAF50000056508 fastq.gz 94.6 MB
EGAF50000056509 fastq.gz 113.4 MB
EGAF50000056510 fastq.gz 112.0 MB
EGAF50000056511 fastq.gz 151.7 MB
EGAF50000056512 fastq.gz 154.3 MB
EGAF50000056513 fastq.gz 124.4 MB
EGAF50000056514 fastq.gz 123.0 MB
EGAF50000056515 fastq.gz 116.7 MB
EGAF50000056516 fastq.gz 118.6 MB
EGAF50000056517 fastq.gz 86.5 MB
EGAF50000056518 fastq.gz 84.9 MB
EGAF50000056519 fastq.gz 94.6 MB
EGAF50000056520 fastq.gz 98.2 MB
EGAF50000056521 fastq.gz 106.8 MB
EGAF50000056522 fastq.gz 105.5 MB
EGAF50000056523 fastq.gz 155.1 MB
EGAF50000056524 fastq.gz 159.8 MB
EGAF50000056525 fastq.gz 133.0 MB
EGAF50000056526 fastq.gz 133.1 MB
EGAF50000056527 fastq.gz 143.8 MB
EGAF50000056528 fastq.gz 144.6 MB
EGAF50000056529 fastq.gz 101.2 MB
EGAF50000056530 fastq.gz 102.7 MB
EGAF50000056531 fastq.gz 133.1 MB
EGAF50000056532 fastq.gz 131.1 MB
EGAF50000056533 fastq.gz 102.5 MB
EGAF50000056534 fastq.gz 104.5 MB
EGAF50000056535 fastq.gz 79.2 MB
EGAF50000056536 fastq.gz 80.6 MB
EGAF50000056537 fastq.gz 176.8 MB
EGAF50000056538 fastq.gz 174.0 MB
EGAF50000056539 fastq.gz 139.1 MB
EGAF50000056540 fastq.gz 143.8 MB
EGAF50000056541 fastq.gz 128.9 MB
EGAF50000056542 fastq.gz 130.8 MB
EGAF50000056543 fastq.gz 82.0 MB
EGAF50000056544 fastq.gz 80.6 MB
EGAF50000056545 fastq.gz 125.3 MB
EGAF50000056546 fastq.gz 129.8 MB
EGAF50000056547 fastq.gz 85.9 MB
EGAF50000056548 fastq.gz 85.2 MB
EGAF50000056549 fastq.gz 107.2 MB
EGAF50000056550 fastq.gz 109.0 MB
EGAF50000056551 fastq.gz 86.2 MB
EGAF50000056552 fastq.gz 85.5 MB
EGAF50000056553 fastq.gz 102.4 MB
EGAF50000056554 fastq.gz 99.9 MB
EGAF50000056555 fastq.gz 136.1 MB
EGAF50000056556 fastq.gz 138.0 MB
EGAF50000056557 fastq.gz 77.3 MB
EGAF50000056558 fastq.gz 78.5 MB
EGAF50000056559 fastq.gz 122.3 MB
EGAF50000056560 fastq.gz 121.9 MB
EGAF50000056561 fastq.gz 94.3 MB
EGAF50000056562 fastq.gz 95.5 MB
EGAF50000056563 fastq.gz 104.4 MB
EGAF50000056564 fastq.gz 104.3 MB
EGAF50000056565 fastq.gz 143.5 MB
EGAF50000056566 fastq.gz 142.1 MB
EGAF50000056567 fastq.gz 97.6 MB
EGAF50000056568 fastq.gz 99.4 MB
EGAF50000056569 fastq.gz 65.5 MB
EGAF50000056570 fastq.gz 66.4 MB
EGAF50000056571 fastq.gz 120.2 MB
EGAF50000056572 fastq.gz 120.8 MB
EGAF50000056573 fastq.gz 110.5 MB
EGAF50000056574 fastq.gz 107.0 MB
EGAF50000056575 fastq.gz 117.4 MB
EGAF50000056576 fastq.gz 119.8 MB
EGAF50000056577 fastq.gz 152.7 MB
EGAF50000056578 fastq.gz 151.3 MB
EGAF50000056579 fastq.gz 87.2 MB
EGAF50000056580 fastq.gz 88.6 MB
EGAF50000056581 fastq.gz 128.7 MB
EGAF50000056582 fastq.gz 129.9 MB
EGAF50000056583 fastq.gz 91.0 MB
EGAF50000056584 fastq.gz 92.8 MB
EGAF50000056585 fastq.gz 166.2 MB
EGAF50000056586 fastq.gz 163.2 MB
EGAF50000056587 fastq.gz 98.0 MB
EGAF50000056588 fastq.gz 98.2 MB
EGAF50000056589 fastq.gz 111.3 MB
EGAF50000056590 fastq.gz 111.4 MB
EGAF50000056591 fastq.gz 102.7 MB
EGAF50000056592 fastq.gz 104.9 MB
EGAF50000056593 fastq.gz 143.8 MB
EGAF50000056594 fastq.gz 147.8 MB
EGAF50000056595 fastq.gz 128.5 MB
EGAF50000056596 fastq.gz 130.0 MB
EGAF50000056597 fastq.gz 109.5 MB
EGAF50000056598 fastq.gz 111.7 MB
EGAF50000056599 fastq.gz 151.0 MB
EGAF50000056600 fastq.gz 149.7 MB
EGAF50000056601 fastq.gz 121.2 MB
EGAF50000056602 fastq.gz 122.3 MB
EGAF50000056603 fastq.gz 116.7 MB
EGAF50000056604 fastq.gz 114.2 MB
EGAF50000056605 fastq.gz 118.7 MB
EGAF50000056606 fastq.gz 121.4 MB
EGAF50000056607 fastq.gz 133.1 MB
EGAF50000056608 fastq.gz 135.5 MB
EGAF50000056609 fastq.gz 114.1 MB
EGAF50000056610 fastq.gz 114.6 MB
EGAF50000056611 fastq.gz 205.8 MB
EGAF50000056612 fastq.gz 210.6 MB
EGAF50000056613 fastq.gz 99.5 MB
EGAF50000056614 fastq.gz 97.2 MB
EGAF50000056615 fastq.gz 98.1 MB
EGAF50000056616 fastq.gz 100.7 MB
EGAF50000056617 fastq.gz 127.6 MB
EGAF50000056618 fastq.gz 124.3 MB
EGAF50000056619 fastq.gz 134.0 MB
EGAF50000056620 fastq.gz 137.5 MB
EGAF50000056621 fastq.gz 104.5 MB
EGAF50000056622 fastq.gz 103.4 MB
EGAF50000056623 fastq.gz 143.5 MB
EGAF50000056624 fastq.gz 138.9 MB
EGAF50000056625 fastq.gz 175.6 MB
EGAF50000056626 fastq.gz 178.5 MB
EGAF50000056627 fastq.gz 127.4 MB
EGAF50000056628 fastq.gz 129.3 MB
138 Files (16.3 GB)