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Phase II Trial with Correlative Genomic Analysis of Durvalumab plus Pazopanib Combination in Patients with Advanced Soft Tissue Sarcomas

This study includes an open-label, phase 2 study to determine the activity of the anti-VEGF receptor tyrosine-kinase inhibitor, pazopanib, combined with the anti-PD-L1 immune checkpoint inhibitor, durvalumab, in unselected advanced sarcomas. We conducted whole exome and transcriptomic sequencing with pre-treatment tissue biopsy to correlate clinical outcomes with molecular and genomic biomarkers to identify patients who would most likely benefit from the combination treatment.

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Data policy

We generally respect the guidelines of NIH genomic data sharing policy, but can be overriden by consensual decision of DAC in exceptional cases.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000082 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000057154 fq.gz 3.3 GB
EGAF50000057155 fq.gz 3.4 GB
EGAF50000057156 fq.gz 2.6 GB
EGAF50000057157 fq.gz 2.8 GB
EGAF50000057158 fq.gz 2.5 GB
EGAF50000057159 fq.gz 2.6 GB
EGAF50000057160 fq.gz 2.5 GB
EGAF50000057161 fq.gz 2.7 GB
EGAF50000057162 fq.gz 2.4 GB
EGAF50000057163 fq.gz 2.6 GB
EGAF50000057164 fq.gz 2.3 GB
EGAF50000057165 fq.gz 2.3 GB
EGAF50000057166 fq.gz 2.7 GB
EGAF50000057167 fq.gz 2.8 GB
EGAF50000057168 fq.gz 2.8 GB
EGAF50000057169 fq.gz 3.0 GB
EGAF50000057170 fq.gz 2.4 GB
EGAF50000057171 fq.gz 2.6 GB
EGAF50000057172 fq.gz 2.5 GB
EGAF50000057173 fq.gz 2.6 GB
EGAF50000057174 fq.gz 6.4 GB
EGAF50000057175 fq.gz 6.0 GB
EGAF50000057176 fq.gz 3.0 GB
EGAF50000057177 fq.gz 3.1 GB
EGAF50000057178 fq.gz 2.5 GB
EGAF50000057179 fq.gz 2.6 GB
EGAF50000057180 fq.gz 4.7 GB
EGAF50000057181 fq.gz 4.5 GB
EGAF50000057182 fq.gz 5.3 GB
EGAF50000057183 fq.gz 5.6 GB
EGAF50000057184 fq.gz 5.8 GB
EGAF50000057185 fq.gz 6.2 GB
EGAF50000057186 fq.gz 6.9 GB
EGAF50000057187 fq.gz 7.2 GB
EGAF50000057188 fq.gz 2.5 GB
EGAF50000057189 fq.gz 2.7 GB
EGAF50000057190 fq.gz 4.8 GB
EGAF50000057191 fq.gz 5.3 GB
EGAF50000057192 fq.gz 44.8 MB
EGAF50000057193 fq.gz 2.2 GB
EGAF50000057194 fq.gz 6.4 GB
EGAF50000057195 fq.gz 6.7 GB
EGAF50000057196 fq.gz 6.0 GB
EGAF50000057197 fq.gz 6.3 GB
EGAF50000057198 fq.gz 6.1 GB
EGAF50000057199 fq.gz 6.5 GB
EGAF50000057200 fq.gz 3.3 GB
EGAF50000057201 fq.gz 3.5 GB
EGAF50000057202 fq.gz 5.4 GB
EGAF50000057203 fq.gz 5.5 GB
EGAF50000057204 fq.gz 2.6 GB
EGAF50000057205 fq.gz 2.7 GB
EGAF50000057206 fq.gz 5.7 GB
EGAF50000057207 fq.gz 6.0 GB
EGAF50000057208 fq.gz 4.9 GB
EGAF50000057209 fq.gz 5.8 GB
EGAF50000057210 fq.gz 4.7 GB
EGAF50000057211 fq.gz 5.1 GB
EGAF50000057212 fq.gz 4.4 GB
EGAF50000057213 fq.gz 4.7 GB
EGAF50000057214 fq.gz 4.9 GB
EGAF50000057215 fq.gz 5.2 GB
EGAF50000057216 fq.gz 5.2 GB
EGAF50000057217 fq.gz 5.5 GB
EGAF50000057218 fq.gz 4.4 GB
EGAF50000057219 fq.gz 4.6 GB
EGAF50000057220 fq.gz 5.8 GB
EGAF50000057221 fq.gz 6.0 GB
EGAF50000057222 fq.gz 4.8 GB
EGAF50000057223 fq.gz 5.0 GB
EGAF50000057224 fq.gz 5.4 GB
EGAF50000057225 fq.gz 5.8 GB
EGAF50000057226 fq.gz 7.1 GB
EGAF50000057227 fq.gz 7.4 GB
EGAF50000057228 fq.gz 5.4 GB
EGAF50000057229 fq.gz 5.8 GB
EGAF50000057230 fq.gz 5.3 GB
EGAF50000057231 fq.gz 5.6 GB
EGAF50000057232 fq.gz 6.3 GB
EGAF50000057233 fq.gz 6.5 GB
EGAF50000057234 fq.gz 5.3 GB
EGAF50000057235 fq.gz 5.6 GB
EGAF50000057236 fq.gz 5.2 GB
EGAF50000057237 fq.gz 5.8 GB
EGAF50000057238 fq.gz 5.0 GB
EGAF50000057239 fq.gz 5.3 GB
EGAF50000057240 fq.gz 5.2 GB
EGAF50000057241 fq.gz 5.5 GB
EGAF50000057242 fq.gz 0 Bytes
EGAF50000057243 fq.gz 5.6 GB
EGAF50000057244 fq.gz 6.5 GB
EGAF50000057245 fq.gz 6.2 GB
EGAF50000057246 fq.gz 4.9 GB
EGAF50000057247 fq.gz 5.3 GB
EGAF50000057248 fq.gz 4.6 GB
EGAF50000057249 fq.gz 5.0 GB
EGAF50000057250 fq.gz 5.7 GB
EGAF50000057251 fq.gz 6.0 GB
EGAF50000057252 fq.gz 6.1 GB
EGAF50000057253 fq.gz 6.5 GB
EGAF50000057254 fq.gz 5.8 GB
EGAF50000057255 fq.gz 6.1 GB
EGAF50000057256 fq.gz 6.1 GB
EGAF50000057257 fq.gz 6.5 GB
EGAF50000057258 fq.gz 5.2 GB
EGAF50000057259 fq.gz 5.5 GB
EGAF50000057260 fq.gz 5.5 GB
EGAF50000057261 fq.gz 5.7 GB
EGAF50000057262 fq.gz 2.4 GB
EGAF50000057263 fq.gz 516.8 MB
EGAF50000057264 fq.gz 3.2 GB
EGAF50000057265 fq.gz 3.4 GB
EGAF50000057266 fq.gz 3.4 GB
EGAF50000057267 fq.gz 3.6 GB
EGAF50000057268 fq.gz 3.0 GB
EGAF50000057269 fq.gz 2.9 GB
EGAF50000057270 fq.gz 2.9 GB
EGAF50000057271 fq.gz 3.1 GB
EGAF50000057272 fq.gz 2.9 GB
EGAF50000057273 fq.gz 3.0 GB
EGAF50000057274 fq.gz 2.6 GB
EGAF50000057275 fq.gz 2.7 GB
EGAF50000057276 fq.gz 2.7 GB
EGAF50000057277 fq.gz 2.9 GB
EGAF50000057278 fq.gz 3.5 GB
EGAF50000057279 fq.gz 3.7 GB
EGAF50000057280 fq.gz 2.7 GB
EGAF50000057281 fq.gz 2.9 GB
EGAF50000057282 fq.gz 2.9 GB
EGAF50000057283 fq.gz 3.1 GB
EGAF50000057284 fq.gz 2.6 GB
EGAF50000057285 fq.gz 2.8 GB
EGAF50000057286 fq.gz 2.6 GB
EGAF50000057287 fq.gz 2.7 GB
EGAF50000057288 fq.gz 2.9 GB
EGAF50000057289 fq.gz 3.0 GB
EGAF50000057290 fq.gz 2.8 GB
EGAF50000057291 fq.gz 3.0 GB
EGAF50000057292 fq.gz 3.0 GB
EGAF50000057293 fq.gz 3.1 GB
EGAF50000057294 fq.gz 3.7 GB
EGAF50000057295 fq.gz 3.9 GB
EGAF50000057296 fq.gz 2.9 GB
EGAF50000057297 fq.gz 3.1 GB
EGAF50000057298 fq.gz 3.2 GB
EGAF50000057299 fq.gz 3.4 GB
EGAF50000057300 fq.gz 2.9 GB
EGAF50000057301 fq.gz 3.1 GB
EGAF50000057302 fq.gz 5.4 GB
EGAF50000057303 fq.gz 5.1 GB
EGAF50000057304 fq.gz 5.7 GB
EGAF50000057305 fq.gz 6.0 GB
EGAF50000057306 fq.gz 4.7 GB
EGAF50000057307 fq.gz 5.4 GB
EGAF50000057308 fq.gz 5.1 GB
EGAF50000057309 fq.gz 5.5 GB
EGAF50000057310 fq.gz 5.1 GB
EGAF50000057311 fq.gz 5.4 GB
EGAF50000057312 fq.gz 4.6 GB
EGAF50000057313 fq.gz 4.9 GB
EGAF50000057314 fq.gz 5.3 GB
EGAF50000057315 fq.gz 5.8 GB
EGAF50000057316 fq.gz 5.8 GB
EGAF50000057317 fq.gz 6.2 GB
EGAF50000057318 fq.gz 4.7 GB
EGAF50000057319 fq.gz 5.1 GB
166 Files (721.8 GB)