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Single-cell RNA-seq of immune cells from human tumor fragments after 48 hour culture ex vivo (Kaptein et al., 2024)

Single-cell RNA-seq profiling of immune cells from human ovarian carcinoma, renal carcinoma and melanoma samples after 48h of ex vivo culture using the patient-derived tumor fragment platform (5 samples total). Samples were cultured in various conditions, including: untreated, CD8-IL2v-treated, CD8-IL2v + LCKi -treated, aPD1-treated, CD8-IL2v + aPD1 -treated, Untargeted IL2-treated, aCD3-treated and aCD3 + CD8-IL2-treated . FASTQ files contain gene expression data, feature barcode antibody capture or TCR data on immune cells from all conditions combined per patient.

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Netherlands Cancer Institute - Antoni van Leeuwenhoek (NKI-AVL) general policy

Data is available under reasonable request. All data requests will be reviewed by the NKI IRB and must be supported by the Principal Investigator of the study. The researcher will need to sign a data access agreement with the NKI after approval.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007712 RNASeq

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000092481 fastq.gz 2.2 GB
EGAF50000092482 fastq.gz 5.7 GB
EGAF50000092491 fastq.gz 806.3 MB
EGAF50000092492 fastq.gz 1.6 GB
EGAF50000092493 fastq.gz 1.7 GB
EGAF50000092494 fastq.gz 699.4 MB
EGAF50000092495 fastq.gz 4.1 GB
EGAF50000092496 fastq.gz 10.4 GB
EGAF50000092497 fastq.gz 731.4 MB
EGAF50000092498 fastq.gz 1.5 GB
EGAF50000092499 fastq.gz 2.0 GB
EGAF50000092500 fastq.gz 819.0 MB
EGAF50000092501 fastq.gz 10.3 GB
EGAF50000092502 fastq.gz 4.0 GB
EGAF50000092503 fastq.gz 884.6 MB
EGAF50000092504 fastq.gz 432.3 MB
EGAF50000092505 fastq.gz 942.7 MB
EGAF50000092506 fastq.gz 2.3 GB
EGAF50000092507 fastq.gz 538.2 MB
EGAF50000092508 fastq.gz 1.3 GB
EGAF50000092509 fastq.gz 312.1 MB
EGAF50000092510 fastq.gz 628.7 MB
EGAF50000092511 fastq.gz 787.1 MB
EGAF50000092512 fastq.gz 1.9 GB
EGAF50000092515 fastq.gz 3.7 GB
EGAF50000092516 fastq.gz 9.6 GB
EGAF50000092517 fastq.gz 4.6 GB
EGAF50000092518 fastq.gz 12.0 GB
EGAF50000092523 fastq.gz 1.6 GB
EGAF50000092524 fastq.gz 794.4 MB
EGAF50000092527 txt 10.3 MB
EGAF50000092528 txt 525.8 MB
32 Files (89.5 GB)