PRADO trial - Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab plus nivolumab in stage III melanoma
The dataset includes WES sequencing data on PRE- treatment biopsies of lymph node metastasis (n=79) The technology used for sequencing is llumina HiSeq. The PRADO trial tested a personalized response-directed treatment approach based on the pathologic response after neoadjuvant ipilimumab plus nivolumab in stage III melanoma patients. In patients achieving a major pathologic response, in their index lymph node (the largest lymph node metastasis at baseline), therapeutic lymph node dissection (TLND) and adjuvant therapy were omitted. Patients with partial response underwent TLND only, whereas patients with pathologic non-response underwent TLND and adjuvant systemic therapy ± synchronous radiotherapy.
- 08/04/2024
- 158 samples
- DAC: EGAC50000000055
- Technology: Illumina NovaSeq 6000
Netherlands Cancer Institute - Antoni van Leeuwenhoek (NKI-AVL) general policy
Data is available under reasonable request. All data requests will be reviewed by the NKI IRB and must be supported by the Principal Investigator of the study. The researcher will need to sign a data access agreement with the NKI after approval.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000000268 | Exome Sequencing |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF50000093695 | fastq.gz | 3.7 GB | ||
| EGAF50000093696 | fastq.gz | 3.8 GB | ||
| EGAF50000093697 | fastq.gz | 3.4 GB | ||
| EGAF50000093698 | fastq.gz | 3.4 GB | ||
| EGAF50000093699 | fastq.gz | 2.7 GB | ||
| EGAF50000093700 | fastq.gz | 2.8 GB | ||
| EGAF50000093701 | fastq.gz | 3.0 GB | ||
| EGAF50000093702 | fastq.gz | 2.9 GB | ||
| EGAF50000093703 | fastq.gz | 3.6 GB | ||
| EGAF50000093704 | fastq.gz | 3.7 GB | ||
| EGAF50000093705 | fastq.gz | 3.1 GB | ||
| EGAF50000093706 | fastq.gz | 3.1 GB | ||
| EGAF50000093707 | fastq.gz | 3.6 GB | ||
| EGAF50000093708 | fastq.gz | 3.5 GB | ||
| EGAF50000093709 | fastq.gz | 2.2 GB | ||
| EGAF50000093710 | fastq.gz | 2.4 GB | ||
| EGAF50000093711 | fastq.gz | 3.4 GB | ||
| EGAF50000093712 | fastq.gz | 3.5 GB | ||
| EGAF50000093713 | fastq.gz | 3.3 GB | ||
| EGAF50000093714 | fastq.gz | 3.3 GB | ||
| EGAF50000093715 | fastq.gz | 3.5 GB | ||
| EGAF50000093716 | fastq.gz | 3.6 GB | ||
| EGAF50000093717 | fastq.gz | 3.5 GB | ||
| EGAF50000093718 | fastq.gz | 3.6 GB | ||
| EGAF50000093719 | fastq.gz | 3.2 GB | ||
| EGAF50000093720 | fastq.gz | 3.3 GB | ||
| EGAF50000093721 | fastq.gz | 3.7 GB | ||
| EGAF50000093722 | fastq.gz | 3.8 GB | ||
| EGAF50000093723 | fastq.gz | 2.8 GB | ||
| EGAF50000093724 | fastq.gz | 2.8 GB | ||
| EGAF50000093725 | fastq.gz | 4.3 GB | ||
| EGAF50000093726 | fastq.gz | 4.4 GB | ||
| EGAF50000093727 | fastq.gz | 5.9 GB | ||
| EGAF50000093728 | fastq.gz | 6.1 GB | ||
| EGAF50000093729 | fastq.gz | 5.4 GB | ||
| EGAF50000093730 | fastq.gz | 5.6 GB | ||
| EGAF50000093731 | fastq.gz | 5.8 GB | ||
| EGAF50000093732 | fastq.gz | 5.6 GB | ||
| EGAF50000093733 | fastq.gz | 6.1 GB | ||
| EGAF50000093734 | fastq.gz | 5.9 GB | ||
| EGAF50000093735 | fastq.gz | 4.8 GB | ||
| EGAF50000093736 | fastq.gz | 5.0 GB | ||
| EGAF50000093737 | fastq.gz | 3.9 GB | ||
| EGAF50000093738 | fastq.gz | 4.0 GB | ||
| EGAF50000093739 | fastq.gz | 4.4 GB | ||
| EGAF50000093740 | fastq.gz | 4.6 GB | ||
| EGAF50000093741 | fastq.gz | 4.7 GB | ||
| EGAF50000093742 | fastq.gz | 4.9 GB | ||
| EGAF50000093743 | fastq.gz | 4.3 GB | ||
| EGAF50000093744 | fastq.gz | 4.3 GB | ||
| EGAF50000093745 | fastq.gz | 3.9 GB | ||
| EGAF50000093746 | fastq.gz | 3.8 GB | ||
| EGAF50000093747 | fastq.gz | 5.3 GB | ||
| EGAF50000093748 | fastq.gz | 4.8 GB | ||
| EGAF50000093749 | fastq.gz | 5.1 GB | ||
| EGAF50000093750 | fastq.gz | 5.3 GB | ||
| EGAF50000093751 | fastq.gz | 4.1 GB | ||
| EGAF50000093752 | fastq.gz | 4.3 GB | ||
| EGAF50000093753 | fastq.gz | 4.2 GB | ||
| EGAF50000093754 | fastq.gz | 4.1 GB | ||
| EGAF50000093755 | fastq.gz | 3.5 GB | ||
| EGAF50000093756 | fastq.gz | 3.8 GB | ||
| EGAF50000093757 | fastq.gz | 4.2 GB | ||
| EGAF50000093758 | fastq.gz | 4.0 GB | ||
| EGAF50000093759 | fastq.gz | 5.7 GB | ||
| EGAF50000093760 | fastq.gz | 5.8 GB | ||
| EGAF50000093761 | fastq.gz | 4.8 GB | ||
| EGAF50000093762 | fastq.gz | 4.9 GB | ||
| EGAF50000093763 | fastq.gz | 3.5 GB | ||
| EGAF50000093764 | fastq.gz | 3.5 GB | ||
| EGAF50000093765 | fastq.gz | 4.6 GB | ||
| EGAF50000093766 | fastq.gz | 4.7 GB | ||
| EGAF50000093767 | fastq.gz | 4.8 GB | ||
| EGAF50000093768 | fastq.gz | 5.0 GB | ||
| EGAF50000093769 | fastq.gz | 4.5 GB | ||
| EGAF50000093770 | fastq.gz | 4.3 GB | ||
| EGAF50000093771 | fastq.gz | 5.3 GB | ||
| EGAF50000093772 | fastq.gz | 5.5 GB | ||
| EGAF50000093773 | fastq.gz | 7.1 GB | ||
| EGAF50000093774 | fastq.gz | 6.8 GB | ||
| EGAF50000093775 | fastq.gz | 5.2 GB | ||
| EGAF50000093776 | fastq.gz | 5.4 GB | ||
| EGAF50000093777 | fastq.gz | 5.5 GB | ||
| EGAF50000093778 | fastq.gz | 5.6 GB | ||
| EGAF50000093779 | fastq.gz | 6.8 GB | ||
| EGAF50000093780 | fastq.gz | 7.1 GB | ||
| EGAF50000093781 | fastq.gz | 5.5 GB | ||
| EGAF50000093782 | fastq.gz | 5.6 GB | ||
| EGAF50000093783 | fastq.gz | 5.9 GB | ||
| EGAF50000093784 | fastq.gz | 6.1 GB | ||
| EGAF50000093785 | fastq.gz | 7.0 GB | ||
| EGAF50000093786 | fastq.gz | 7.3 GB | ||
| EGAF50000093787 | fastq.gz | 4.7 GB | ||
| EGAF50000093788 | fastq.gz | 4.9 GB | ||
| EGAF50000093789 | fastq.gz | 5.5 GB | ||
| EGAF50000093790 | fastq.gz | 5.3 GB | ||
| EGAF50000093791 | fastq.gz | 4.1 GB | ||
| EGAF50000093792 | fastq.gz | 3.9 GB | ||
| EGAF50000093793 | fastq.gz | 5.2 GB | ||
| EGAF50000093794 | fastq.gz | 5.4 GB | ||
| EGAF50000093795 | fastq.gz | 5.0 GB | ||
| EGAF50000093796 | fastq.gz | 4.9 GB | ||
| EGAF50000093797 | fastq.gz | 4.6 GB | ||
| EGAF50000093798 | fastq.gz | 4.7 GB | ||
| EGAF50000093799 | fastq.gz | 5.3 GB | ||
| EGAF50000093800 | fastq.gz | 5.5 GB | ||
| EGAF50000093801 | fastq.gz | 5.2 GB | ||
| EGAF50000093802 | fastq.gz | 5.0 GB | ||
| EGAF50000093803 | fastq.gz | 5.3 GB | ||
| EGAF50000093804 | fastq.gz | 5.6 GB | ||
| EGAF50000093805 | fastq.gz | 4.1 GB | ||
| EGAF50000093806 | fastq.gz | 4.2 GB | ||
| EGAF50000093807 | fastq.gz | 4.3 GB | ||
| EGAF50000093808 | fastq.gz | 4.5 GB | ||
| EGAF50000093809 | fastq.gz | 5.5 GB | ||
| EGAF50000093810 | fastq.gz | 5.2 GB | ||
| EGAF50000093811 | fastq.gz | 4.3 GB | ||
| EGAF50000093812 | fastq.gz | 4.4 GB | ||
| EGAF50000093813 | fastq.gz | 3.7 GB | ||
| EGAF50000093814 | fastq.gz | 3.9 GB | ||
| EGAF50000093815 | fastq.gz | 4.4 GB | ||
| EGAF50000093816 | fastq.gz | 4.3 GB | ||
| EGAF50000093817 | fastq.gz | 4.2 GB | ||
| EGAF50000093818 | fastq.gz | 4.4 GB | ||
| EGAF50000093819 | fastq.gz | 3.9 GB | ||
| EGAF50000093820 | fastq.gz | 4.0 GB | ||
| EGAF50000093821 | fastq.gz | 4.8 GB | ||
| EGAF50000093822 | fastq.gz | 4.6 GB | ||
| EGAF50000093823 | fastq.gz | 4.0 GB | ||
| EGAF50000093824 | fastq.gz | 4.1 GB | ||
| EGAF50000093825 | fastq.gz | 4.3 GB | ||
| EGAF50000093826 | fastq.gz | 4.4 GB | ||
| EGAF50000093827 | fastq.gz | 5.3 GB | ||
| EGAF50000093828 | fastq.gz | 5.2 GB | ||
| EGAF50000093829 | fastq.gz | 4.9 GB | ||
| EGAF50000093830 | fastq.gz | 5.0 GB | ||
| EGAF50000093831 | fastq.gz | 5.3 GB | ||
| EGAF50000093832 | fastq.gz | 5.2 GB | ||
| EGAF50000093833 | fastq.gz | 4.7 GB | ||
| EGAF50000093834 | fastq.gz | 4.8 GB | ||
| EGAF50000093835 | fastq.gz | 4.4 GB | ||
| EGAF50000093836 | fastq.gz | 4.6 GB | ||
| EGAF50000093837 | fastq.gz | 5.3 GB | ||
| EGAF50000093838 | fastq.gz | 5.2 GB | ||
| EGAF50000093839 | fastq.gz | 4.8 GB | ||
| EGAF50000093840 | fastq.gz | 4.9 GB | ||
| EGAF50000093841 | fastq.gz | 6.1 GB | ||
| EGAF50000093842 | fastq.gz | 6.3 GB | ||
| EGAF50000093843 | fastq.gz | 4.4 GB | ||
| EGAF50000093844 | fastq.gz | 4.4 GB | ||
| EGAF50000093845 | fastq.gz | 7.4 GB | ||
| EGAF50000093846 | fastq.gz | 7.8 GB | ||
| EGAF50000093847 | fastq.gz | 4.2 GB | ||
| EGAF50000093848 | fastq.gz | 4.5 GB | ||
| EGAF50000093849 | fastq.gz | 4.1 GB | ||
| EGAF50000093850 | fastq.gz | 4.3 GB | ||
| EGAF50000093851 | fastq.gz | 5.4 GB | ||
| EGAF50000093852 | fastq.gz | 5.4 GB | ||
| EGAF50000093853 | fastq.gz | 4.1 GB | ||
| EGAF50000093854 | fastq.gz | 4.2 GB | ||
| EGAF50000093855 | fastq.gz | 5.6 GB | ||
| EGAF50000093856 | fastq.gz | 5.4 GB | ||
| EGAF50000093857 | fastq.gz | 4.8 GB | ||
| EGAF50000093858 | fastq.gz | 5.0 GB | ||
| EGAF50000093859 | fastq.gz | 3.8 GB | ||
| EGAF50000093860 | fastq.gz | 3.9 GB | ||
| EGAF50000093861 | fastq.gz | 5.1 GB | ||
| EGAF50000093862 | fastq.gz | 4.9 GB | ||
| EGAF50000093863 | fastq.gz | 5.9 GB | ||
| EGAF50000093864 | fastq.gz | 6.1 GB | ||
| EGAF50000093865 | fastq.gz | 7.7 GB | ||
| EGAF50000093866 | fastq.gz | 7.4 GB | ||
| EGAF50000093867 | fastq.gz | 5.1 GB | ||
| EGAF50000093868 | fastq.gz | 5.1 GB | ||
| EGAF50000093869 | fastq.gz | 5.5 GB | ||
| EGAF50000093870 | fastq.gz | 5.6 GB | ||
| EGAF50000093871 | fastq.gz | 4.0 GB | ||
| EGAF50000093872 | fastq.gz | 4.0 GB | ||
| EGAF50000093873 | fastq.gz | 4.0 GB | ||
| EGAF50000093874 | fastq.gz | 4.1 GB | ||
| EGAF50000093875 | fastq.gz | 4.3 GB | ||
| EGAF50000093876 | fastq.gz | 4.4 GB | ||
| EGAF50000093877 | fastq.gz | 3.7 GB | ||
| EGAF50000093878 | fastq.gz | 3.6 GB | ||
| EGAF50000093879 | fastq.gz | 4.0 GB | ||
| EGAF50000093880 | fastq.gz | 3.9 GB | ||
| EGAF50000093881 | fastq.gz | 3.4 GB | ||
| EGAF50000093882 | fastq.gz | 3.5 GB | ||
| EGAF50000093883 | fastq.gz | 3.1 GB | ||
| EGAF50000093884 | fastq.gz | 3.2 GB | ||
| EGAF50000093885 | fastq.gz | 3.6 GB | ||
| EGAF50000093886 | fastq.gz | 3.7 GB | ||
| EGAF50000093887 | fastq.gz | 3.5 GB | ||
| EGAF50000093888 | fastq.gz | 3.6 GB | ||
| EGAF50000093889 | fastq.gz | 4.8 GB | ||
| EGAF50000093890 | fastq.gz | 4.7 GB | ||
| EGAF50000093891 | fastq.gz | 3.0 GB | ||
| EGAF50000093892 | fastq.gz | 2.9 GB | ||
| EGAF50000093893 | fastq.gz | 2.7 GB | ||
| EGAF50000093894 | fastq.gz | 2.7 GB | ||
| EGAF50000093895 | fastq.gz | 3.2 GB | ||
| EGAF50000093896 | fastq.gz | 3.2 GB | ||
| EGAF50000093897 | fastq.gz | 3.6 GB | ||
| EGAF50000093898 | fastq.gz | 3.7 GB | ||
| EGAF50000093899 | fastq.gz | 3.2 GB | ||
| EGAF50000093900 | fastq.gz | 3.1 GB | ||
| EGAF50000093901 | fastq.gz | 2.7 GB | ||
| EGAF50000093902 | fastq.gz | 2.8 GB | ||
| EGAF50000093903 | fastq.gz | 4.0 GB | ||
| EGAF50000093904 | fastq.gz | 4.1 GB | ||
| EGAF50000093905 | fastq.gz | 2.9 GB | ||
| EGAF50000093906 | fastq.gz | 3.0 GB | ||
| EGAF50000093907 | fastq.gz | 3.6 GB | ||
| EGAF50000093908 | fastq.gz | 3.7 GB | ||
| EGAF50000093909 | fastq.gz | 3.2 GB | ||
| EGAF50000093910 | fastq.gz | 3.2 GB | ||
| EGAF50000093911 | fastq.gz | 3.2 GB | ||
| EGAF50000093912 | fastq.gz | 3.1 GB | ||
| EGAF50000093913 | fastq.gz | 3.9 GB | ||
| EGAF50000093914 | fastq.gz | 4.0 GB | ||
| EGAF50000093915 | fastq.gz | 3.0 GB | ||
| EGAF50000093916 | fastq.gz | 3.1 GB | ||
| EGAF50000093917 | fastq.gz | 3.3 GB | ||
| EGAF50000093918 | fastq.gz | 3.3 GB | ||
| EGAF50000093919 | fastq.gz | 3.8 GB | ||
| EGAF50000093920 | fastq.gz | 3.6 GB | ||
| EGAF50000093921 | fastq.gz | 4.2 GB | ||
| EGAF50000093922 | fastq.gz | 4.3 GB | ||
| EGAF50000093923 | fastq.gz | 3.4 GB | ||
| EGAF50000093924 | fastq.gz | 3.5 GB | ||
| EGAF50000093925 | fastq.gz | 2.8 GB | ||
| EGAF50000093926 | fastq.gz | 2.9 GB | ||
| EGAF50000093927 | fastq.gz | 4.0 GB | ||
| EGAF50000093928 | fastq.gz | 4.2 GB | ||
| EGAF50000093929 | fastq.gz | 2.9 GB | ||
| EGAF50000093930 | fastq.gz | 3.0 GB | ||
| EGAF50000093931 | fastq.gz | 3.1 GB | ||
| EGAF50000093932 | fastq.gz | 3.0 GB | ||
| EGAF50000093933 | fastq.gz | 3.0 GB | ||
| EGAF50000093934 | fastq.gz | 3.1 GB | ||
| EGAF50000093935 | fastq.gz | 2.9 GB | ||
| EGAF50000093936 | fastq.gz | 2.9 GB | ||
| EGAF50000093937 | fastq.gz | 3.1 GB | ||
| EGAF50000093938 | fastq.gz | 3.2 GB | ||
| EGAF50000093939 | fastq.gz | 2.5 GB | ||
| EGAF50000093940 | fastq.gz | 2.5 GB | ||
| EGAF50000093941 | fastq.gz | 2.6 GB | ||
| EGAF50000093942 | fastq.gz | 2.8 GB | ||
| EGAF50000093943 | fastq.gz | 3.0 GB | ||
| EGAF50000093944 | fastq.gz | 2.9 GB | ||
| EGAF50000093945 | fastq.gz | 3.7 GB | ||
| EGAF50000093946 | fastq.gz | 3.8 GB | ||
| EGAF50000093947 | fastq.gz | 2.8 GB | ||
| EGAF50000093948 | fastq.gz | 2.9 GB | ||
| EGAF50000093949 | fastq.gz | 2.5 GB | ||
| EGAF50000093950 | fastq.gz | 2.6 GB | ||
| EGAF50000093951 | fastq.gz | 3.2 GB | ||
| EGAF50000093952 | fastq.gz | 3.1 GB | ||
| EGAF50000093953 | fastq.gz | 2.8 GB | ||
| EGAF50000093954 | fastq.gz | 2.9 GB | ||
| EGAF50000093955 | fastq.gz | 2.5 GB | ||
| EGAF50000093956 | fastq.gz | 2.6 GB | ||
| EGAF50000093957 | fastq.gz | 2.7 GB | ||
| EGAF50000093958 | fastq.gz | 2.8 GB | ||
| EGAF50000093959 | fastq.gz | 2.2 GB | ||
| EGAF50000093960 | fastq.gz | 2.2 GB | ||
| EGAF50000093961 | fastq.gz | 2.9 GB | ||
| EGAF50000093962 | fastq.gz | 3.0 GB | ||
| EGAF50000093963 | fastq.gz | 3.1 GB | ||
| EGAF50000093964 | fastq.gz | 3.2 GB | ||
| EGAF50000093965 | fastq.gz | 3.2 GB | ||
| EGAF50000093966 | fastq.gz | 3.3 GB | ||
| EGAF50000093967 | fastq.gz | 3.4 GB | ||
| EGAF50000093968 | fastq.gz | 3.5 GB | ||
| EGAF50000093969 | fastq.gz | 3.2 GB | ||
| EGAF50000093970 | fastq.gz | 3.4 GB | ||
| EGAF50000093971 | fastq.gz | 2.6 GB | ||
| EGAF50000093972 | fastq.gz | 2.7 GB | ||
| EGAF50000093973 | fastq.gz | 2.9 GB | ||
| EGAF50000093974 | fastq.gz | 2.9 GB | ||
| EGAF50000093975 | fastq.gz | 3.2 GB | ||
| EGAF50000093976 | fastq.gz | 3.3 GB | ||
| EGAF50000093977 | fastq.gz | 2.8 GB | ||
| EGAF50000093978 | fastq.gz | 2.9 GB | ||
| EGAF50000093979 | fastq.gz | 3.4 GB | ||
| EGAF50000093980 | fastq.gz | 3.5 GB | ||
| EGAF50000093981 | fastq.gz | 3.5 GB | ||
| EGAF50000093982 | fastq.gz | 3.5 GB | ||
| EGAF50000093983 | fastq.gz | 2.8 GB | ||
| EGAF50000093984 | fastq.gz | 2.9 GB | ||
| EGAF50000093985 | fastq.gz | 2.6 GB | ||
| EGAF50000093986 | fastq.gz | 2.7 GB | ||
| EGAF50000093987 | fastq.gz | 3.2 GB | ||
| EGAF50000093988 | fastq.gz | 3.3 GB | ||
| EGAF50000093989 | fastq.gz | 2.6 GB | ||
| EGAF50000093990 | fastq.gz | 2.5 GB | ||
| EGAF50000093991 | fastq.gz | 2.4 GB | ||
| EGAF50000093992 | fastq.gz | 2.5 GB | ||
| EGAF50000093993 | fastq.gz | 3.3 GB | ||
| EGAF50000093994 | fastq.gz | 3.3 GB | ||
| EGAF50000093995 | fastq.gz | 3.1 GB | ||
| EGAF50000093996 | fastq.gz | 3.2 GB | ||
| EGAF50000093997 | fastq.gz | 2.7 GB | ||
| EGAF50000093998 | fastq.gz | 2.8 GB | ||
| EGAF50000093999 | fastq.gz | 3.3 GB | ||
| EGAF50000094000 | fastq.gz | 3.4 GB | ||
| EGAF50000094001 | fastq.gz | 3.0 GB | ||
| EGAF50000094002 | fastq.gz | 3.0 GB | ||
| EGAF50000094003 | fastq.gz | 3.0 GB | ||
| EGAF50000094004 | fastq.gz | 3.2 GB | ||
| EGAF50000094005 | fastq.gz | 3.9 GB | ||
| EGAF50000094006 | fastq.gz | 4.0 GB | ||
| EGAF50000094007 | fastq.gz | 3.5 GB | ||
| EGAF50000094008 | fastq.gz | 3.6 GB | ||
| EGAF50000094009 | fastq.gz | 2.3 GB | ||
| EGAF50000094010 | fastq.gz | 2.5 GB | ||
| 316 Files (1.3 TB) | ||||