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Resistance to selective FGFR2 inhibitors across FGFR2-driven malignancies

18 patients were biopsied at resistance to an FGFR inhibitor with tumor WES and/or WTS performed to identify resistance mechanisms to selective FGFR2 inhibitors across FGFR2-driven malignancies.

Request Access

Policy to have access to the data of "Resistance to selective FGFR2 inhibitors across FGFR2-driven malignancies"

Preamble Gustave Roussy set up a Data Access Committee (DAC) to process requests for access to the “Resistance to selective FGFR2 inhibitors across FGFR2-driven malignancies” data, from now on named LUFR_FGFR2 data. Article I. Data Access Committee Article I.1 Composition LUFR_FGFR2 study’s DAC is composed of Luc FRIBOULET, Francesco FACCHINETTI and Alicia Tran Dien. Article I.1 Missions LUFR_FGFR2 Study’s DAC is responsible for authorizing access to the data. Article II. Request for access to data Article II.1 Composition of the application file The data access request requires on demand: - A summary of the study (synopsis template) : it can be very light. We just need to know the general question that is going to be addressed; - The CNIL declaration : we can take care of the submission part to the CNIL, once we receive it; - The standard contractual clauses signed if your country is located outside of the European Community (check if your country is concerned : https://www.cnil.fr/en/data-protection-around-the-world) - The opinion issued by an Institution Review Board / or ethical committee that evaluated the project and the composition of the committee(s), if any; - The confidentiality form - The documentation necessary to demonstrate compliance with all its data protection and security obligations (a security charter); - This data access policy signed Article II.2 Application procedures The request for access to the data is free. It is done by mail to the following addresses Luc.FRIBOULET@gustaveroussy.fr FRANCESCO.FACCHINETTI@gustaveroussy.fr ALICIA.TRAN-DIEN@gustaveroussy.fr Article II.3. Examination of applications Following the filing of the file with the DAC, the latter: - verify its good orientation and completeness. Otherwise, the DAC will contact the requester for further information; - instruct the request for access to the data within one month after receiving the complete file. This time is given as an indication. Article III. Conditions of use of the data The applicants undertake to respect all the following measures and to have them respected by their staff as well as any other person(s) assisting them with the use of the data: - To collect only data adequate, relevant, limited and strictly necessary to the specific treatment that it with these data; - Do not use the data to which they can access for purposes other than those indicated in the application file; - Disclose this data only to persons duly authorized by reason of their duties and who have been indicated in the data access request file; - Do not make any copy of this data except that it is necessary for the execution of their research; - Respect the patient decision to withdraw his/her data from the project - Take all necessary measures to avoid misuse or fraudulent use of this data; - Ensure that only secure means of communication will be used to transfer this data; - At the end of the research project, to fully restore the data, computer files and any information related to these data. When this task falls within its remit, the applicants undertake to ensure that the persons from whom they collect and / or use the data have been previously informed of the specific treatment that they are carrying out with their data. Article IV. Notification of data breach As soon as it becomes aware of this and within a maximum of seventy-two (72) hours, the requester notifies the DAC of any data breach. The requester provides to the DAC at the time of notification of the incident, or if this is not reasonably possible as soon as possible after the notification of the data breach, the following information regarding their violation: 1) The nature of the data breach; 2) The estimated number of people involved; 3) Categories of the person(s) involved; 4) The categories of Data concerned; 5) The estimated number of Data violated; Measures taken to remedy the data breach, including, measures to limit adverse effects and potential risks. The applicants shall as far as possible assist the DAC in reporting the data breach to the relevant control authorization and / or to the person(s) involved in the data breach. Article V. Data destruction At the end of the research, the applicants undertake, after having made sure of the terms relating to reversibility: - Destroy all data - Return all data to the DAC - Return the data to the subcontractor designated by the DAC The return must be accompanied by the destruction of all data (including copies) in the information systems of the applicant and their collaborators.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000305 Exome Sequencing
EGAS50000000306 RNASeq

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000100431 fastq.gz 2.9 GB
EGAF50000100432 fastq.gz 2.7 GB
EGAF50000100433 fastq.gz 3.6 GB
EGAF50000100434 fastq.gz 3.9 GB
EGAF50000100435 fastq.gz 3.3 GB
EGAF50000100436 fastq.gz 3.6 GB
EGAF50000100437 fastq.gz 2.9 GB
EGAF50000100438 fastq.gz 2.9 GB
EGAF50000100439 fastq.gz 3.8 GB
EGAF50000100440 fastq.gz 3.7 GB
EGAF50000100441 fastq.gz 2.8 GB
EGAF50000100442 fastq.gz 2.9 GB
EGAF50000100443 fastq.gz 3.3 GB
EGAF50000100444 fastq.gz 3.4 GB
EGAF50000100445 fastq.gz 2.7 GB
EGAF50000100446 fastq.gz 2.7 GB
EGAF50000100447 fastq.gz 2.9 GB
EGAF50000100448 fastq.gz 2.9 GB
EGAF50000100449 fastq.gz 2.1 GB
EGAF50000100450 fastq.gz 2.1 GB
EGAF50000100451 fastq.gz 3.6 GB
EGAF50000100452 fastq.gz 3.6 GB
EGAF50000100453 fastq.gz 2.1 GB
EGAF50000100454 fastq.gz 2.1 GB
EGAF50000100455 fastq.gz 3.9 GB
EGAF50000100456 fastq.gz 4.0 GB
EGAF50000100457 fq.gz 4.3 GB
EGAF50000100458 fq.gz 4.2 GB
EGAF50000100459 fq.gz 4.7 GB
EGAF50000100460 fq.gz 4.6 GB
EGAF50000100461 fastq.gz 3.1 GB
EGAF50000100462 fastq.gz 3.4 GB
EGAF50000100463 fastq.gz 4.8 GB
EGAF50000100464 fastq.gz 4.7 GB
EGAF50000100465 fastq.gz 4.0 GB
EGAF50000100466 fastq.gz 4.2 GB
EGAF50000100467 fastq.gz 3.8 GB
EGAF50000100468 fastq.gz 4.0 GB
EGAF50000100469 fq.gz 1.9 GB
EGAF50000100470 fq.gz 1.9 GB
EGAF50000100471 fq.gz 2.3 GB
EGAF50000100472 fq.gz 2.4 GB
EGAF50000100473 fq.gz 2.4 GB
EGAF50000100474 fq.gz 2.4 GB
EGAF50000100475 fq.gz 1.7 GB
EGAF50000100476 fq.gz 1.7 GB
EGAF50000100477 fq.gz 2.0 GB
EGAF50000100478 fq.gz 2.1 GB
EGAF50000100479 fq.gz 1.4 GB
EGAF50000100480 fq.gz 1.5 GB
EGAF50000100481 fq.gz 1.6 GB
EGAF50000100482 fq.gz 1.6 GB
EGAF50000100483 fq.gz 2.3 GB
EGAF50000100484 fq.gz 2.2 GB
EGAF50000100485 fastq.gz 2.5 GB
EGAF50000100486 fastq.gz 2.6 GB
EGAF50000100487 fastq.gz 3.4 GB
EGAF50000100488 fastq.gz 3.7 GB
EGAF50000100489 fastq.gz 3.2 GB
EGAF50000100490 fastq.gz 3.4 GB
EGAF50000100491 fastq.gz 3.4 GB
EGAF50000100492 fastq.gz 3.6 GB
EGAF50000100493 fastq.gz 2.5 GB
EGAF50000100494 fastq.gz 2.6 GB
EGAF50000100495 fastq.gz 4.3 GB
EGAF50000100496 fastq.gz 4.3 GB
EGAF50000100497 fastq.gz 2.4 GB
EGAF50000100498 fastq.gz 2.6 GB
EGAF50000100499 fastq.gz 4.2 GB
EGAF50000100500 fastq.gz 3.9 GB
EGAF50000100501 fastq.gz 2.7 GB
EGAF50000100502 fastq.gz 2.7 GB
EGAF50000100503 fastq.gz 5.3 GB
EGAF50000100504 fastq.gz 5.3 GB
EGAF50000100505 fastq.gz 2.2 GB
EGAF50000100506 fastq.gz 2.2 GB
EGAF50000100507 fastq.gz 3.6 GB
EGAF50000100508 fastq.gz 3.7 GB
EGAF50000100509 fastq.gz 1.6 GB
EGAF50000100510 fastq.gz 1.6 GB
EGAF50000100511 fastq.gz 3.9 GB
EGAF50000100512 fastq.gz 4.0 GB
EGAF50000100513 fastq.gz 2.2 GB
EGAF50000100514 fastq.gz 2.2 GB
EGAF50000100515 fastq.gz 4.4 GB
EGAF50000100516 fastq.gz 4.7 GB
EGAF50000100517 fastq.gz 4.3 GB
EGAF50000100518 fastq.gz 4.4 GB
EGAF50000100519 fq.gz 6.3 GB
EGAF50000100520 fq.gz 6.4 GB
EGAF50000100521 fq.gz 4.6 GB
EGAF50000100522 fq.gz 4.7 GB
EGAF50000100523 fq.gz 4.3 GB
EGAF50000100524 fq.gz 4.4 GB
EGAF50000100525 fastq.gz 5.2 GB
EGAF50000100526 fastq.gz 5.2 GB
EGAF50000100527 fq.gz 3.8 GB
EGAF50000100528 fq.gz 3.8 GB
EGAF50000100529 fq.gz 3.3 GB
EGAF50000100530 fq.gz 3.3 GB
EGAF50000100531 fq.gz 4.1 GB
EGAF50000100532 fq.gz 4.1 GB
EGAF50000100533 fq.gz 4.0 GB
EGAF50000100534 fq.gz 4.0 GB
EGAF50000100535 fq.gz 3.8 GB
EGAF50000100536 fq.gz 4.0 GB
EGAF50000100537 fq.gz 3.5 GB
EGAF50000100538 fq.gz 3.4 GB
EGAF50000100539 fq.gz 4.4 GB
EGAF50000100540 fq.gz 4.4 GB
EGAF50000100541 fq.gz 3.6 GB
EGAF50000100542 fq.gz 3.7 GB
EGAF50000100543 fq.gz 4.7 GB
EGAF50000100544 fq.gz 4.6 GB
EGAF50000100545 fq.gz 3.5 GB
EGAF50000100546 fq.gz 3.7 GB
EGAF50000100547 fq.gz 3.2 GB
EGAF50000100548 fq.gz 3.3 GB
EGAF50000100549 fq.gz 5.1 GB
EGAF50000100550 fq.gz 5.2 GB
EGAF50000100551 fq.gz 6.2 GB
EGAF50000100552 fq.gz 6.0 GB
EGAF50000100553 fq.gz 7.5 GB
EGAF50000100554 fq.gz 7.7 GB
EGAF50000100555 fq.gz 3.3 GB
EGAF50000100556 fq.gz 3.2 GB
126 Files (444.9 GB)