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PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development

The coding variant (p.Arg192His) in the transcription factor PAX4 is associated with an altered risk for type 2 diabetes (T2D) in East Asian populations. In mice, Pax4 is essential for beta cell formation but its role on human beta cell development and/or function is unknown. Participants carrying the PAX4 p.His192 allele exhibited decreased pancreatic beta cell function compared to homozygotes for the p.192Arg allele in a cross-sectional study in which we carried out an intravenous glucose tolerance test and an oral glucose tolerance test. In a pedigree of a patient with young onset diabetes, several members carry a newly identified p.Tyr186X allele. In the human beta cell model, EndoC-βH1, PAX4 knockdown led to impaired insulin secretion, reduced total insulin content, and altered hormone gene expression. Deletion of PAX4 in human induced pluripotent stem cell (hiPSC)-derived islet-like cells resulted in derepression of alpha cell gene expression. In vitro differentiation of hiPSCs carrying PAX4 p.His192 and p.X186 risk alleles exhibited increased polyhormonal endocrine cell formation and reduced insulin content that can be reversed with gene correction. Together, we demonstrate the role of PAX4 in human endocrine cell development, beta cell function, and its contribution to T2D-risk.

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Data Access Policy of the Datasets from the Translational Genomics of Diabetes Lab at Stanford University

DATA ACCESS AGREEMENT This agreement governs the terms on which access will be granted to the RNA sequencing data generated as part of the CALCOCO2 study. In signing this agreement, You are agreeing to be bound by the terms and conditions of access set out in this agreement. For the sake of clarity, the terms of access set out in this agreement apply both to the User and the User’s Institution (as defined below). User Institution and User are referred to within the agreement as “You” and “Your” shall be construed accordingly. Definitions: Investigators means the group of investigators based in Stanford, US and Oxford, UK which have generated the Data. Data means all and any human genetic data obtained from the Investigators. Data Subject means a person, who has been informed of the purpose for which the Data is held and has given his/her informed consent thereto. User means a researcher whose User Institution has previously completed this Data Access Agreement and has received acknowledgement of its acceptance. Publications means, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User Institution means the organization at which the User is employed, affiliated or enrolled. Terms and Conditions: In signing this Agreement: 1. You agree to use the Data only for the advancement of medical research, according to the consent obtained from sample donors. 2. You agree not to use the Data or any part thereof for the creation of products for sale or for any commercial purpose. 3. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 4. You agree not to attempt to link the data provided under this agreement to other information or archive data available for the data sets provided, even if access to that data has been formally granted to you, or it is freely available without restriction, without specific permission being sought from the relevant access committees. 5. You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others, except as necessary for data/safety monitoring or programme management. Should You wish to share the Data with a collaborator outside the same Institution, the third party must make a separate application for access to the Data. 6. You agree to use the data for the approved purpose and project described in your application; use of the data for a new purpose or project will require a new application and approval. 7. You agree to acknowledge in any work based in whole or part on the Data, the published paper from which the Data derives. 8. You accept that the Investigators, the original data creators, depositors or copyright holders, or the funders of the Data or any part of the Data supplied: a. bear no legal responsibility for the accuracy or comprehensiveness of the Data; and b. accept no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason. 9. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted. 10. You recognise that nothing in this agreement shall operate to transfer to the User Institution any intellectual property rights relating to the Data. The User Institution has the right to develop intellectual property based on comparisons with their own data. 11. You accept that this agreement will terminate immediately upon any breach of this agreement by You and You will be required to destroy any Data held. 12. You accept that it may be necessary for the Investigators or its appointed agent to alter the terms of this agreement from time to time in order to address new concerns. In this event, the Investigators or its appointed agent will contact You to inform You of any changes and You agree that Your continued use of the Data shall be dependent on the parties entering into a new version of the Agreement. 13. You accept that the Data is protected by and subject to international laws and that You are responsible for ensuring compliance with any such applicable law. The Translational Genomics of Diabetes Lab Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures in countries that have no national laws comparable to that which pertain in the EAA. 14. This agreement shall be construed, interpreted and governed by the laws of US and UK and shall be subject to the non-exclusive jurisdiction of the US and UK courts.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006036 RNASeq

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005802408 fastq.gz 660.2 MB
EGAF00005802409 fastq.gz 677.6 MB
EGAF00005802410 fastq.gz 1.3 GB
EGAF00005802411 fastq.gz 1.3 GB
EGAF00005802412 fastq.gz 522.0 MB
EGAF00005802413 fastq.gz 535.0 MB
EGAF00005802414 fastq.gz 637.5 MB
EGAF00005802415 fastq.gz 654.1 MB
EGAF00005810097 fastq.gz 1.6 GB
EGAF00005810098 fastq.gz 1.6 GB
EGAF00005810099 fastq.gz 1.1 GB
EGAF00005810100 fastq.gz 1.1 GB
EGAF00005810101 fastq.gz 572.7 MB
EGAF00005810102 fastq.gz 590.5 MB
EGAF00005810103 fastq.gz 1.2 GB
EGAF00005810104 fastq.gz 1.2 GB
EGAF00005810105 fastq.gz 539.6 MB
EGAF00005810106 fastq.gz 559.4 MB
EGAF00005810107 fastq.gz 1.3 GB
EGAF00005810108 fastq.gz 1.4 GB
EGAF00005810109 fastq.gz 635.8 MB
EGAF00005810110 fastq.gz 659.8 MB
EGAF00005810111 fastq.gz 678.6 MB
EGAF00005810112 fastq.gz 703.2 MB
EGAF00005810113 fastq.gz 504.9 MB
EGAF00005810114 fastq.gz 524.7 MB
EGAF00005810115 fastq.gz 487.3 MB
EGAF00005810116 fastq.gz 496.4 MB
EGAF00005810117 fastq.gz 688.5 MB
EGAF00005810118 fastq.gz 708.6 MB
EGAF00005810119 fastq.gz 1.3 GB
EGAF00005810120 fastq.gz 1.4 GB
EGAF00005810121 fastq.gz 517.4 MB
EGAF00005810122 fastq.gz 525.6 MB
EGAF00005810123 fastq.gz 657.2 MB
EGAF00005810124 fastq.gz 678.3 MB
EGAF00005810125 fastq.gz 510.1 MB
EGAF00005810126 fastq.gz 542.0 MB
EGAF00005810127 fastq.gz 724.9 MB
EGAF00005810128 fastq.gz 745.3 MB
EGAF00005810129 fastq.gz 461.3 MB
EGAF00005810130 fastq.gz 470.9 MB
EGAF00005810131 fastq.gz 527.7 MB
EGAF00005810132 fastq.gz 556.3 MB
EGAF00005810133 fastq.gz 1.1 GB
EGAF00005810134 fastq.gz 1.1 GB
EGAF00005810135 fastq.gz 539.2 MB
EGAF00005810136 fastq.gz 558.9 MB
EGAF00005810137 fastq.gz 1.3 GB
EGAF00005810138 fastq.gz 1.4 GB
EGAF00005810139 fastq.gz 735.1 MB
EGAF00005810140 fastq.gz 750.4 MB
EGAF00005810141 fastq.gz 630.0 MB
EGAF00005810142 fastq.gz 643.2 MB
EGAF00005810143 fastq.gz 546.3 MB
EGAF00005810144 fastq.gz 555.7 MB
EGAF00005810145 fastq.gz 1.3 GB
EGAF00005810146 fastq.gz 1.4 GB
EGAF00005810147 fastq.gz 665.8 MB
EGAF00005810148 fastq.gz 688.6 MB
EGAF00005810149 fastq.gz 546.3 MB
EGAF00005810150 fastq.gz 570.5 MB
EGAF00005810151 fastq.gz 660.0 MB
EGAF00005810152 fastq.gz 677.3 MB
EGAF00005810153 fastq.gz 1.0 GB
EGAF00005810154 fastq.gz 1.1 GB
EGAF00005810155 fastq.gz 1.3 GB
EGAF00005810156 fastq.gz 1.3 GB
EGAF00005810157 fastq.gz 524.0 MB
EGAF00005810158 fastq.gz 533.6 MB
EGAF00005810159 fastq.gz 753.4 MB
EGAF00005810160 fastq.gz 779.5 MB
EGAF00005810161 fastq.gz 636.0 MB
EGAF00005810162 fastq.gz 657.0 MB
EGAF00005810163 fastq.gz 1.2 GB
EGAF00005810164 fastq.gz 1.3 GB
EGAF00005810165 fastq.gz 1.3 GB
EGAF00005810166 fastq.gz 1.3 GB
EGAF00005810167 fastq.gz 541.3 MB
EGAF00005810168 fastq.gz 544.1 MB
EGAF00005810169 fastq.gz 680.3 MB
EGAF00005810170 fastq.gz 702.5 MB
EGAF00005810171 fastq.gz 1.3 GB
EGAF00005810172 fastq.gz 1.4 GB
EGAF00005810173 fastq.gz 543.3 MB
EGAF00005810174 fastq.gz 561.3 MB
EGAF00005810175 fastq.gz 657.8 MB
EGAF00005810176 fastq.gz 686.5 MB
EGAF00005810177 fastq.gz 460.7 MB
EGAF00005810178 fastq.gz 470.1 MB
EGAF00005810179 fastq.gz 479.1 MB
EGAF00005810180 fastq.gz 490.6 MB
EGAF00005810181 fastq.gz 616.2 MB
EGAF00005810182 fastq.gz 634.3 MB
EGAF00005810183 fastq.gz 652.8 MB
EGAF00005810184 fastq.gz 672.7 MB
EGAF00005810185 fastq.gz 550.9 MB
EGAF00005810186 fastq.gz 551.0 MB
EGAF00005810187 fastq.gz 1.4 GB
EGAF00005810188 fastq.gz 1.5 GB
EGAF00005810189 fastq.gz 713.8 MB
EGAF00005810190 fastq.gz 741.1 MB
EGAF00005810191 fastq.gz 1.2 GB
EGAF00005810192 fastq.gz 1.2 GB
EGAF00005810193 fastq.gz 519.1 MB
EGAF00005810194 fastq.gz 537.0 MB
EGAF00005810195 fastq.gz 699.6 MB
EGAF00005810196 fastq.gz 716.0 MB
EGAF00005810197 fastq.gz 1.4 GB
EGAF00005810198 fastq.gz 1.4 GB
EGAF00005810199 fastq.gz 483.1 MB
EGAF00005810200 fastq.gz 486.4 MB
EGAF00005810201 fastq.gz 527.3 MB
EGAF00005810202 fastq.gz 542.0 MB
EGAF00005810203 fastq.gz 1.3 GB
EGAF00005810204 fastq.gz 1.3 GB
EGAF00005810205 fastq.gz 1.6 GB
EGAF00005810206 fastq.gz 1.6 GB
EGAF00005810207 fastq.gz 790.8 MB
EGAF00005810208 fastq.gz 817.2 MB
EGAF00005810209 fastq.gz 671.1 MB
EGAF00005810210 fastq.gz 697.3 MB
EGAF00005810211 fastq.gz 514.0 MB
EGAF00005810212 fastq.gz 521.1 MB
EGAF00005810213 fastq.gz 1.3 GB
EGAF00005810214 fastq.gz 1.3 GB
EGAF00005810215 fastq.gz 699.0 MB
EGAF00005810216 fastq.gz 725.8 MB
EGAF00005810217 fastq.gz 1.4 GB
EGAF00005810218 fastq.gz 1.4 GB
EGAF00005810219 fastq.gz 526.4 MB
EGAF00005810220 fastq.gz 543.3 MB
EGAF00005810221 fastq.gz 684.8 MB
EGAF00005810222 fastq.gz 715.6 MB
EGAF00005810223 fastq.gz 1.4 GB
EGAF00005810224 fastq.gz 1.4 GB
EGAF00005810225 fastq.gz 1.3 GB
EGAF00005810226 fastq.gz 1.4 GB
EGAF00005810227 fastq.gz 682.3 MB
EGAF00005810228 fastq.gz 707.1 MB
EGAF00005810229 fastq.gz 471.3 MB
EGAF00005810230 fastq.gz 495.4 MB
EGAF00005810231 fastq.gz 627.8 MB
EGAF00005810232 fastq.gz 639.8 MB
EGAF00005810233 fastq.gz 1.3 GB
EGAF00005810234 fastq.gz 1.3 GB
EGAF00005810235 fastq.gz 645.7 MB
EGAF00005810236 fastq.gz 678.1 MB
EGAF00005810237 fastq.gz 1.3 GB
EGAF00005810238 fastq.gz 1.3 GB
EGAF00005810239 fastq.gz 491.1 MB
EGAF00005810240 fastq.gz 501.4 MB
EGAF00005810241 fastq.gz 1.2 GB
EGAF00005810242 fastq.gz 1.2 GB
EGAF00005810243 fastq.gz 638.7 MB
EGAF00005810244 fastq.gz 660.3 MB
EGAF00005810245 fastq.gz 1.3 GB
EGAF00005810246 fastq.gz 1.3 GB
EGAF00005810247 fastq.gz 723.1 MB
EGAF00005810248 fastq.gz 743.9 MB
EGAF00005810249 fastq.gz 678.6 MB
EGAF00005810250 fastq.gz 696.1 MB
EGAF00005810251 fastq.gz 1.0 GB
EGAF00005810252 fastq.gz 1.1 GB
EGAF00005810253 fastq.gz 428.6 MB
EGAF00005810254 fastq.gz 434.6 MB
EGAF00005810255 fastq.gz 605.5 MB
EGAF00005810256 fastq.gz 624.9 MB
EGAF00005810257 fastq.gz 1.4 GB
EGAF00005810258 fastq.gz 1.4 GB
EGAF00005810259 fastq.gz 567.2 MB
EGAF00005810260 fastq.gz 580.8 MB
EGAF00005810261 fastq.gz 486.6 MB
EGAF00005810262 fastq.gz 494.9 MB
EGAF00005810263 fastq.gz 1.2 GB
EGAF00005810264 fastq.gz 1.2 GB
EGAF00005810265 fastq.gz 551.3 MB
EGAF00005810266 fastq.gz 581.5 MB
EGAF00005810267 fastq.gz 627.1 MB
EGAF00005810268 fastq.gz 642.4 MB
EGAF00005810269 fastq.gz 1.2 GB
EGAF00005810270 fastq.gz 1.2 GB
EGAF00005810271 fastq.gz 515.7 MB
EGAF00005810272 fastq.gz 527.4 MB
EGAF00005810273 fastq.gz 491.1 MB
EGAF00005810274 fastq.gz 495.0 MB
EGAF00005810275 fastq.gz 652.3 MB
EGAF00005810276 fastq.gz 670.3 MB
EGAF00005810277 fastq.gz 645.4 MB
EGAF00005810278 fastq.gz 662.0 MB
EGAF00005810279 fastq.gz 561.8 MB
EGAF00005810280 fastq.gz 584.2 MB
EGAF00005810281 fastq.gz 715.5 MB
EGAF00005810282 fastq.gz 739.8 MB
EGAF00005810283 fastq.gz 1.4 GB
EGAF00005810284 fastq.gz 1.4 GB
EGAF00005810285 fastq.gz 811.6 MB
EGAF00005810286 fastq.gz 833.3 MB
EGAF00005810287 fastq.gz 1.6 GB
EGAF00005810288 fastq.gz 1.6 GB
EGAF00005810289 fastq.gz 724.2 MB
EGAF00005810290 fastq.gz 744.7 MB
EGAF00005810291 fastq.gz 1.4 GB
EGAF00005810292 fastq.gz 1.5 GB
EGAF00005810293 fastq.gz 487.0 MB
EGAF00005810294 fastq.gz 498.8 MB
EGAF00005810295 fastq.gz 620.8 MB
EGAF00005810296 fastq.gz 634.4 MB
EGAF00005810297 fastq.gz 1.5 GB
EGAF00005810298 fastq.gz 1.5 GB
EGAF00005810299 fastq.gz 1.2 GB
EGAF00005810300 fastq.gz 1.2 GB
EGAF00005810301 fastq.gz 745.5 MB
EGAF00005810302 fastq.gz 773.1 MB
EGAF00005810303 fastq.gz 1.4 GB
EGAF00005810304 fastq.gz 1.4 GB
EGAF00005810305 fastq.gz 675.6 MB
EGAF00005810306 fastq.gz 697.0 MB
EGAF00005810307 fastq.gz 567.7 MB
EGAF00005810308 fastq.gz 580.1 MB
EGAF00005810309 fastq.gz 512.7 MB
EGAF00005810310 fastq.gz 529.0 MB
EGAF00005810311 fastq.gz 735.4 MB
EGAF00005810312 fastq.gz 755.7 MB
EGAF00005810313 fastq.gz 576.3 MB
EGAF00005810314 fastq.gz 591.1 MB
EGAF00005810315 fastq.gz 672.8 MB
EGAF00005810316 fastq.gz 687.8 MB
EGAF00005810317 fastq.gz 1.3 GB
EGAF00005810318 fastq.gz 1.3 GB
EGAF00005810319 fastq.gz 459.0 MB
EGAF00005810320 fastq.gz 472.0 MB
EGAF00005810321 fastq.gz 1.4 GB
EGAF00005810322 fastq.gz 1.5 GB
EGAF00005810323 fastq.gz 596.1 MB
EGAF00005810324 fastq.gz 609.9 MB
EGAF00005810325 fastq.gz 691.8 MB
EGAF00005810326 fastq.gz 714.0 MB
EGAF00005810327 fastq.gz 1.3 GB
EGAF00005810328 fastq.gz 1.4 GB
EGAF00005810329 fastq.gz 585.0 MB
EGAF00005810330 fastq.gz 591.0 MB
EGAF00005810331 fastq.gz 489.8 MB
EGAF00005810332 fastq.gz 506.4 MB
EGAF00005810333 fastq.gz 539.0 MB
EGAF00005810334 fastq.gz 555.7 MB
EGAF00005810335 fastq.gz 986.4 MB
EGAF00005810336 fastq.gz 1.0 GB
EGAF00005810337 fastq.gz 559.5 MB
EGAF00005810338 fastq.gz 574.5 MB
EGAF00005810339 fastq.gz 1.4 GB
EGAF00005810340 fastq.gz 1.4 GB
EGAF00005810341 fastq.gz 1.3 GB
EGAF00005810342 fastq.gz 1.3 GB
EGAF00005810343 fastq.gz 706.5 MB
EGAF00005810344 fastq.gz 729.2 MB
EGAF00005810345 fastq.gz 569.5 MB
EGAF00005810346 fastq.gz 578.1 MB
EGAF00005810347 fastq.gz 533.1 MB
EGAF00005810348 fastq.gz 548.4 MB
EGAF00005810349 fastq.gz 615.9 MB
EGAF00005810350 fastq.gz 630.7 MB
EGAF00005810351 fastq.gz 485.7 MB
EGAF00005810352 fastq.gz 490.5 MB
EGAF00005810353 fastq.gz 1.2 GB
EGAF00005810354 fastq.gz 1.2 GB
EGAF00005810355 fastq.gz 509.8 MB
EGAF00005810356 fastq.gz 517.1 MB
EGAF00005810357 fastq.gz 1.3 GB
EGAF00005810358 fastq.gz 1.4 GB
EGAF00005810359 fastq.gz 669.6 MB
EGAF00005810360 fastq.gz 702.1 MB
EGAF00005810361 fastq.gz 482.2 MB
EGAF00005810362 fastq.gz 495.1 MB
EGAF00005810363 fastq.gz 538.1 MB
EGAF00005810364 fastq.gz 569.1 MB
EGAF00005810365 fastq.gz 1.3 GB
EGAF00005810366 fastq.gz 1.3 GB
EGAF00005810367 fastq.gz 558.2 MB
EGAF00005810368 fastq.gz 590.9 MB
EGAF00005810369 fastq.gz 526.4 MB
EGAF00005810370 fastq.gz 543.3 MB
EGAF00005810371 fastq.gz 666.6 MB
EGAF00005810372 fastq.gz 689.0 MB
EGAF00005810373 fastq.gz 724.0 MB
EGAF00005810374 fastq.gz 756.7 MB
EGAF00005810375 fastq.gz 1.4 GB
EGAF00005810376 fastq.gz 1.5 GB
EGAF00005810377 fastq.gz 1.3 GB
EGAF00005810378 fastq.gz 1.3 GB
EGAF00005810379 fastq.gz 527.1 MB
EGAF00005810380 fastq.gz 544.2 MB
EGAF00005810381 fastq.gz 1.3 GB
EGAF00005810382 fastq.gz 1.3 GB
EGAF00005810383 fastq.gz 542.7 MB
EGAF00005810384 fastq.gz 551.8 MB
EGAF00005810385 fastq.gz 663.2 MB
EGAF00005810386 fastq.gz 687.7 MB
EGAF00005810387 fastq.gz 523.8 MB
EGAF00005810388 fastq.gz 546.7 MB
EGAF00005810389 fastq.gz 767.9 MB
EGAF00005810390 fastq.gz 784.9 MB
EGAF00005810391 fastq.gz 1.6 GB
EGAF00005810392 fastq.gz 1.6 GB
EGAF00005810393 fastq.gz 796.7 MB
EGAF00005810394 fastq.gz 817.4 MB
EGAF00005810395 fastq.gz 562.7 MB
EGAF00005810396 fastq.gz 591.4 MB
EGAF00005810397 fastq.gz 1.3 GB
EGAF00005810398 fastq.gz 1.4 GB
EGAF00005810399 fastq.gz 539.8 MB
EGAF00005810400 fastq.gz 557.3 MB
EGAF00005810401 fastq.gz 541.8 MB
EGAF00005810402 fastq.gz 562.6 MB
EGAF00005810403 fastq.gz 669.5 MB
EGAF00005810404 fastq.gz 690.4 MB
EGAF00005810405 fastq.gz 655.4 MB
EGAF00005810406 fastq.gz 675.1 MB
EGAF00005810407 fastq.gz 1.3 GB
EGAF00005810408 fastq.gz 1.3 GB
EGAF00005810409 fastq.gz 1.2 GB
EGAF00005810410 fastq.gz 1.2 GB
EGAF00005810411 fastq.gz 1.2 GB
EGAF00005810412 fastq.gz 1.3 GB
EGAF00005810413 fastq.gz 810.7 MB
EGAF00005810414 fastq.gz 837.5 MB
EGAF00005810415 fastq.gz 599.2 MB
EGAF00005810416 fastq.gz 613.9 MB
EGAF00005810417 fastq.gz 622.9 MB
EGAF00005810418 fastq.gz 639.1 MB
EGAF00005810419 fastq.gz 458.2 MB
EGAF00005810420 fastq.gz 471.4 MB
EGAF00005810421 fastq.gz 1.4 GB
EGAF00005810422 fastq.gz 1.4 GB
EGAF00005810423 fastq.gz 546.7 MB
EGAF00005810424 fastq.gz 553.1 MB
EGAF00005810425 fastq.gz 568.2 MB
EGAF00005810426 fastq.gz 581.5 MB
EGAF00005810427 fastq.gz 1.5 GB
EGAF00005810428 fastq.gz 1.5 GB
EGAF00005810429 fastq.gz 550.3 MB
EGAF00005810430 fastq.gz 564.9 MB
EGAF00005810431 fastq.gz 697.0 MB
EGAF00005810432 fastq.gz 715.3 MB
EGAF00005810433 fastq.gz 1.4 GB
EGAF00005810434 fastq.gz 1.4 GB
EGAF00005810435 fastq.gz 1.2 GB
EGAF00005810436 fastq.gz 1.3 GB
EGAF00005810437 fastq.gz 645.5 MB
EGAF00005810438 fastq.gz 670.6 MB
EGAF00005810439 fastq.gz 1.5 GB
EGAF00005810440 fastq.gz 1.5 GB
EGAF00005810441 fastq.gz 587.3 MB
EGAF00005810442 fastq.gz 607.8 MB
EGAF00005810443 fastq.gz 525.4 MB
EGAF00005810444 fastq.gz 544.1 MB
EGAF00005810445 fastq.gz 577.8 MB
EGAF00005810446 fastq.gz 593.4 MB
EGAF00005810447 fastq.gz 1.3 GB
EGAF00005810448 fastq.gz 1.3 GB
EGAF00005810449 fastq.gz 585.8 MB
EGAF00005810450 fastq.gz 610.1 MB
EGAF00005810451 fastq.gz 1.1 GB
EGAF00005810452 fastq.gz 1.2 GB
EGAF00005810453 fastq.gz 615.6 MB
EGAF00005810454 fastq.gz 628.9 MB
EGAF00005810455 fastq.gz 1.2 GB
EGAF00005810456 fastq.gz 1.2 GB
EGAF00005810457 fastq.gz 608.0 MB
EGAF00005810458 fastq.gz 627.0 MB
EGAF00005810459 fastq.gz 1.4 GB
EGAF00005810460 fastq.gz 1.4 GB
EGAF00005810461 fastq.gz 1.1 GB
EGAF00005810462 fastq.gz 1.1 GB
EGAF00005810463 fastq.gz 601.7 MB
EGAF00005810464 fastq.gz 615.1 MB
EGAF00005810465 fastq.gz 615.9 MB
EGAF00005810466 fastq.gz 636.0 MB
EGAF00005810467 fastq.gz 591.7 MB
EGAF00005810468 fastq.gz 610.8 MB
EGAF00005810469 fastq.gz 631.4 MB
EGAF00005810470 fastq.gz 656.4 MB
EGAF00005810471 fastq.gz 705.7 MB
EGAF00005810472 fastq.gz 718.8 MB
384 Files (324.9 GB)