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As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Single-cell RNA sequencing of pediatric Hodgkin Lymphoma to study the inhibition of T cell subtypes

Here, we applied single-cell RNA-sequencing (scRNA-seq) on isolated HRS cells and the immune cells from the same pediatric classical Hodgkin Lymphoma (cHL) tumors. Specifically, 13 cHL patients and 3 reactive lymph node control samples were included in this cohort. This allowed us to identify genes of cell surface proteins that are consistently overexpressed in HRS cells and can potentially be used as targets for antibody-drug conjugates or CAR T cells. Finally, we identify potential interactions by which HRS cells inhibit T cells, among which the Galectin-1/CD69 and HLA-DRA/LAG3 interactions. However, high levels of inter-patient heterogeneity of the interaction strength were observed. In conclusion, this study identifies new potential therapeutic targets for cHL and highlights the importance of studying heterogeneity when identifying therapy targets.

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Data Access Agreement Princess Máxima Center for pediatric oncology

The Princess Maxima Center for pediatric oncology default access policy to enable re-production of research and re-use of data for scientific purposes. Please contact the DAC (EGAC00001001864) for the most up to date policies.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000432 RNASeq

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF50000145308 fastq.gz 12.3 GB
EGAF50000145309 fastq.gz 12.2 GB
EGAF50000145310 fastq.gz 29.1 GB Report
EGAF50000145311 fastq.gz 28.7 GB Report
EGAF50000145312 fastq.gz 4.9 GB Report
EGAF50000145313 fastq.gz 350.1 MB Report
EGAF50000145314 fastq.gz 366.3 MB Report
EGAF50000145315 fastq.gz 344.4 MB Report
EGAF50000145316 fastq.gz 362.1 MB Report
EGAF50000145317 fastq.gz 371.1 MB Report
EGAF50000145318 fastq.gz 387.7 MB Report
EGAF50000145319 fastq.gz 363.9 MB Report
EGAF50000145320 fastq.gz 382.4 MB Report
EGAF50000145321 fastq.gz 170.2 MB Report
EGAF50000145322 fastq.gz 15.3 GB Report
EGAF50000145323 fastq.gz 688.3 MB Report
EGAF50000145324 fastq.gz 166.0 MB Report
EGAF50000145325 fastq.gz 676.6 MB Report
EGAF50000145326 fastq.gz 174.7 MB Report
EGAF50000145327 fastq.gz 703.6 MB Report
EGAF50000145328 fastq.gz 172.8 MB Report
EGAF50000145329 fastq.gz 694.0 MB Report
EGAF50000145330 fastq.gz 223.9 MB Report
EGAF50000145331 fastq.gz 914.7 MB Report
EGAF50000145332 fastq.gz 221.6 MB Report
EGAF50000145333 fastq.gz 901.7 MB Report
EGAF50000145334 fastq.gz 181.0 MB Report
EGAF50000145335 fastq.gz 728.5 MB Report
EGAF50000145336 fastq.gz 181.5 MB Report
EGAF50000145337 fastq.gz 732.6 MB Report
EGAF50000145338 fastq.gz 156.5 MB Report
EGAF50000145339 fastq.gz 635.9 MB Report
EGAF50000145340 fastq.gz 157.2 MB Report
EGAF50000145341 fastq.gz 640.0 MB Report
EGAF50000145342 fastq.gz 181.8 MB Report
EGAF50000145343 fastq.gz 742.6 MB Report
EGAF50000145344 fastq.gz 182.5 MB Report
EGAF50000145345 fastq.gz 747.1 MB Report
EGAF50000145346 fastq.gz 210.5 MB Report
EGAF50000145347 fastq.gz 868.9 MB Report
EGAF50000145348 fastq.gz 211.2 MB Report
EGAF50000145349 fastq.gz 873.7 MB Report
EGAF50000145350 fastq.gz 195.7 MB Report
EGAF50000145351 fastq.gz 766.3 MB Report
EGAF50000145352 fastq.gz 193.9 MB Report
EGAF50000145353 fastq.gz 754.7 MB Report
EGAF50000145354 fastq.gz 158.1 MB Report
EGAF50000145355 fastq.gz 610.2 MB Report
EGAF50000145356 fastq.gz 156.4 MB Report
EGAF50000145357 fastq.gz 599.6 MB Report
EGAF50000145358 fastq.gz 229.2 MB Report
EGAF50000145359 fastq.gz 904.3 MB Report
EGAF50000145360 fastq.gz 227.2 MB Report
EGAF50000145361 fastq.gz 890.9 MB Report
EGAF50000145362 fastq.gz 147.0 MB Report
EGAF50000145363 fastq.gz 574.2 MB Report
EGAF50000145364 fastq.gz 145.3 MB Report
EGAF50000145365 fastq.gz 563.6 MB Report
EGAF50000145366 fastq.gz 152.6 MB Report
EGAF50000145367 fastq.gz 601.7 MB Report
EGAF50000145368 fastq.gz 151.1 MB Report
EGAF50000145369 fastq.gz 592.0 MB Report
EGAF50000145370 fastq.gz 185.0 MB Report
EGAF50000145371 fastq.gz 739.4 MB Report
EGAF50000145372 fastq.gz 182.8 MB Report
EGAF50000145373 fastq.gz 726.0 MB Report
EGAF50000145374 fastq.gz 159.8 MB Report
EGAF50000145375 fastq.gz 644.0 MB Report
EGAF50000145376 fastq.gz 158.2 MB Report
EGAF50000145377 fastq.gz 633.9 MB Report
EGAF50000145378 fastq.gz 253.2 MB Report
EGAF50000145379 fastq.gz 1.0 GB Report
EGAF50000145380 fastq.gz 250.5 MB Report
EGAF50000145381 fastq.gz 998.4 MB Report
EGAF50000145382 fastq.gz 287.8 MB Report
EGAF50000145383 fastq.gz 889.8 MB Report
EGAF50000145384 fastq.gz 285.8 MB Report
EGAF50000145385 fastq.gz 878.7 MB Report
EGAF50000145386 fastq.gz 305.2 MB Report
EGAF50000145387 fastq.gz 904.6 MB Report
EGAF50000145388 fastq.gz 302.6 MB Report
EGAF50000145389 fastq.gz 890.9 MB Report
EGAF50000145390 fastq.gz 202.9 MB Report
EGAF50000145391 fastq.gz 600.4 MB Report
EGAF50000145392 fastq.gz 202.6 MB Report
EGAF50000145393 fastq.gz 597.0 MB Report
EGAF50000145394 fastq.gz 204.4 MB Report
EGAF50000145395 fastq.gz 606.4 MB Report
EGAF50000145396 fastq.gz 203.8 MB Report
EGAF50000145397 fastq.gz 602.2 MB Report
EGAF50000145398 fastq.gz 186.1 MB Report
EGAF50000145399 fastq.gz 545.4 MB Report
EGAF50000145400 fastq.gz 186.2 MB Report
EGAF50000145401 fastq.gz 543.7 MB Report
EGAF50000145402 fastq.gz 229.7 MB Report
EGAF50000145403 fastq.gz 682.0 MB Report
EGAF50000145404 fastq.gz 229.5 MB Report
EGAF50000145405 fastq.gz 679.3 MB Report
EGAF50000145406 fastq.gz 203.7 MB Report
EGAF50000145407 fastq.gz 614.3 MB Report
EGAF50000145408 fastq.gz 203.5 MB Report
EGAF50000145409 fastq.gz 610.9 MB Report
EGAF50000145410 fastq.gz 190.4 MB Report
EGAF50000145411 fastq.gz 573.6 MB Report
EGAF50000145412 fastq.gz 189.7 MB Report
EGAF50000145413 fastq.gz 569.3 MB Report
EGAF50000145414 fastq.gz 210.9 MB Report
EGAF50000145415 fastq.gz 630.1 MB Report
EGAF50000145416 fastq.gz 210.8 MB Report
EGAF50000145417 fastq.gz 627.6 MB Report
110 Files (149.4 GB)